SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6dgk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKP_A_NVPA999_1
(HIV-1 RT, A-CHAIN)		 6dgk -
(-) 		5 / 11 LEU A 115
ASN A 176
VAL A 180
GLY A 179
LEU A 144
 None
 1.42A 1fkpA-6dgkA:
undetectable		 1fkpA-6dgkA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_B_RITB301_2
(PROTEASE)		 6dgk -
(-) 		5 / 11 GLY A 158
VAL A 192
ILE A 182
GLY A 184
ILE A 128
 None
 0.94A 1n49B-6dgkA:
undetectable		 1n49B-6dgkA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_D_RITD401_1
(PROTEASE)		 6dgk -
(-) 		5 / 11 GLY A 158
VAL A 192
ILE A 182
GLY A 184
ILE A 128
 None
 0.93A 1n49C-6dgkA:
undetectable		 1n49C-6dgkA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_1
(POL POLYPROTEIN)		 6dgk -
(-) 		5 / 12 GLY A 158
ILE A 182
GLY A 183
GLY A 184
ILE A 128
 None
 0.78A 2avvA-6dgkA:
undetectable		 2avvA-6dgkA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_3
(HIV-1 PROTEASE)		 6dgk -
(-) 		5 / 12 GLY A 158
ILE A 182
GLY A 183
GLY A 184
ILE A 128
 None
 0.79A 3cyxB-6dgkA:
undetectable		 3cyxB-6dgkA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQY_A_BEZA401_0
(THIOREDOXIN)		 6dgk -
(-) 		4 / 8 ILE A 182
VAL A 178
GLN A 199
SER A 195
 None
 0.89A 5dqyA-6dgkA:
undetectable		 5dqyA-6dgkA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXC_A_ZITA307_1
(PREDICTED
AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 6dgk -
(-) 		4 / 5 ASP A  92
GLU A  96
ARG A 148
THR A  94
 None
 1.27A 5uxcA-6dgkA:
undetectable		 5uxcA-6dgkA:
undetectable