SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6din'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX4_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 6din DTDP-4-DEHYDRORHAMNO
SE 3,5-EPIMERASE
(Pseudomonas
aeruginosa) 		4 / 7 GLY A  70
THR A 134
PHE A  35
PHE A  14
 None
 1.23A 2qx4A-6dinA:
undetectable
2qx4B-6dinA:
undetectable		 2qx4A-6dinA:
20.61
2qx4B-6dinA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O7W_A_SAMA801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 1)		 6din DTDP-4-DEHYDRORHAMNO
SE 3,5-EPIMERASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 119
ASP A  86
LEU A  87
ARG A  88
GLU A 142
 None
 1.04A 3o7wA-6dinA:
undetectable		 3o7wA-6dinA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_B_SAMB201_0
(YAEB-LIKE PROTEIN
RPA0152)		 6din DTDP-4-DEHYDRORHAMNO
SE 3,5-EPIMERASE
(Pseudomonas
aeruginosa) 		3 / 3 LYS A 132
ARG A  74
LYS A  -2
 None
 1.27A 3okxA-6dinA:
undetectable		 3okxA-6dinA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFG_B_LEUB289_0
(GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT)		 6din DTDP-4-DEHYDRORHAMNO
SE 3,5-EPIMERASE
(Pseudomonas
aeruginosa) 		3 / 3 PHE A 120
SER A  51
SER A  53
 None
 0.90A 3ufgB-6dinA:
undetectable		 3ufgB-6dinA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOC_A_SAMA401_0
(PAVINE
N-METHYLTRANSFERASE)		 6din DTDP-4-DEHYDRORHAMNO
SE 3,5-EPIMERASE
(Pseudomonas
aeruginosa) 		5 / 12 ASP A  82
VAL A  83
VAL A 146
LEU A  61
HIS A  62
 None
 0.94A 5kocA-6dinA:
undetectable		 5kocA-6dinA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_A_ERMA2001_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 6din DTDP-4-DEHYDRORHAMNO
SE 3,5-EPIMERASE
(Pseudomonas
aeruginosa) 		5 / 12 VAL A  83
ALA A  38
PHE A  14
LEU A 102
VAL A  73
 None
 1.04A 5tudA-6dinA:
undetectable		 5tudA-6dinA:
11.06