SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6dip'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G5Y_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 6dip NOCTURNIN
(Homo
sapiens) 		5 / 12 ILE A 320
LEU A 247
ALA A 251
PHE A 240
ILE A 282
 None
 1.07A 1g5yB-6dipA:
undetectable		 1g5yB-6dipA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QCA_A_FUAA221_1
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6dip NOCTURNIN
(Homo
sapiens) 		4 / 7 CYH A 273
SER A 276
PHE A 245
LEU A 238
 None
 0.84A 1qcaA-6dipA:
undetectable		 1qcaA-6dipA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6O_B_SAMB500_0
(HYPOTHETICAL PROTEIN)		 6dip NOCTURNIN
(Homo
sapiens) 		4 / 6 VAL A 321
PHE A 280
PRO A 318
THR A 312
 None
 1.26A 2q6oB-6dipA:
undetectable		 2q6oB-6dipA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O02_B_JN3B1_1
(CELL INVASION
PROTEIN SIPD)		 6dip NOCTURNIN
(Homo
sapiens) 		5 / 10 PHE A 216
ASN A 252
ALA A 266
LEU A 287
LEU A 255
 None
 1.08A 3o02A-6dipA:
undetectable
3o02B-6dipA:
undetectable		 3o02A-6dipA:
12.70
3o02B-6dipA:
12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TOP_B_ACRB1_2
(MALTASE-GLUCOAMYLASE
, INTESTINAL)		 6dip NOCTURNIN
(Homo
sapiens) 		4 / 5 PRO A 233
ILE A 179
TRP A 172
PHE A 216
 None
 1.44A 3topB-6dipA:
0.1		 3topB-6dipA:
6.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P3Q_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 6dip NOCTURNIN
(Homo
sapiens) 		4 / 5 ASP A 234
LEU A 155
ARG A 367
ARG A 290
 None
 1.44A 4p3qA-6dipA:
undetectable		 4p3qA-6dipA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP8_C_ASCC501_1
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)		 6dip NOCTURNIN
(Homo
sapiens) 		3 / 3 SER A 412
TYR A 410
ASP A 377
 None
 0.87A 4rp8C-6dipA:
undetectable		 4rp8C-6dipA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5I_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 6dip NOCTURNIN
(Homo
sapiens) 		3 / 3 ASP A 234
ARG A 367
ARG A 290
 None
 0.64A 4x5iA-6dipA:
undetectable		 4x5iA-6dipA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EAJ_B_FOLB201_1
(DIHYDROFOLATE
REDUCTASE)		 6dip NOCTURNIN
(Homo
sapiens) 		3 / 3 ASP A 234
ARG A 367
ARG A 290
 None
 0.75A 5eajB-6dipA:
undetectable		 5eajB-6dipA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G2P_A_TRPA502_0
(FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA)		 6dip NOCTURNIN
(Homo
sapiens) 		4 / 7 ARG A 127
TYR A 348
LEU A 132
VAL A 130
 None
 0.92A 6g2pA-6dipA:
undetectable		 6g2pA-6dipA:
undetectable