SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6djw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_B_CUB4_0
(BETA-CARBONIC
ANHYDRASE)
6djw RBR-TYPE E3
UBIQUITIN
TRANSFERASE,RBR-TYPE
E3 UBIQUITIN
TRANSFERASE

(Bactrocera
dorsalis)
4 / 6 CYH A 324
CYH A 288
PRO A 287
SER A 331
ZN  A1004 (-2.3A)
ZN  A1004 (-2.3A)
None
ZN  A1004 ( 4.9A)
1.41A 1ekjA-6djwA:
0.0
1ekjB-6djwA:
0.0
1ekjA-6djwA:
undetectable
1ekjB-6djwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHS_A_CLMA999_0
(PROTEIN
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE))
6djw RBR-TYPE E3
UBIQUITIN
TRANSFERASE,RBR-TYPE
E3 UBIQUITIN
TRANSFERASE

(Bactrocera
dorsalis)
5 / 12 ILE A  72
ILE A  52
ILE A  85
VAL A  44
LEU A  46
None
1.02A 1qhsA-6djwA:
undetectable
1qhsA-6djwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHY_A_CLMA999_0
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE)
6djw RBR-TYPE E3
UBIQUITIN
TRANSFERASE,RBR-TYPE
E3 UBIQUITIN
TRANSFERASE

(Bactrocera
dorsalis)
5 / 12 ILE A  72
ILE A  52
ILE A  85
VAL A  44
LEU A  46
None
1.03A 1qhyA-6djwA:
undetectable
1qhyA-6djwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA153_0
(ILEAL BILE
ACID-BINDING PROTEIN)
6djw RBR-TYPE E3
UBIQUITIN
TRANSFERASE,RBR-TYPE
E3 UBIQUITIN
TRANSFERASE

(Bactrocera
dorsalis)
4 / 5 THR A 321
PHE A 339
PHE A 299
TYR A 302
None
1.35A 3em0A-6djwA:
undetectable
3em0A-6djwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J7Z_A_ERYA9000_0
(23S RRNA
50S RIBOSOMAL
PROTEIN L22
ERMCL NASCENT CHAIN)
6djw RBR-TYPE E3
UBIQUITIN
TRANSFERASE,RBR-TYPE
E3 UBIQUITIN
TRANSFERASE

(Bactrocera
dorsalis)
3 / 3 LYS A  71
ILE A 218
PHE A 239
None
0.97A 3j7zS-6djwA:
undetectable
3j7za-6djwA:
undetectable
3j7zS-6djwA:
undetectable
3j7za-6djwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUG_A_SUEA1201_2
(NS3 PROTEASE, NS4A
PROTEIN)
6djw RBR-TYPE E3
UBIQUITIN
TRANSFERASE,RBR-TYPE
E3 UBIQUITIN
TRANSFERASE

(Bactrocera
dorsalis)
4 / 5 GLN A 351
TYR A 320
LEU A 341
LYS A 340
None
0.95A 3sugA-6djwA:
undetectable
3sugA-6djwA:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IMS_A_ACTA708_0
(ACETOLACTATE
SYNTHASE CATALYTIC
SUBUNIT,
MITOCHONDRIAL)
6djw RBR-TYPE E3
UBIQUITIN
TRANSFERASE,RBR-TYPE
E3 UBIQUITIN
TRANSFERASE

(Bactrocera
dorsalis)
3 / 3 GLY A  27
GLY A  28
GLN A  92
None
0.45A 5imsA-6djwA:
undetectable
5imsA-6djwA:
undetectable