SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6dk4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_C_PPFC413_1
(PHOSPHONOACETATE
HYDROLASE)		 6dk4 FERRIC UPTAKE
REGULATION PROTEIN
(Campylobacter
jejuni) 		4 / 8 ASP A  97
HIS A  84
HIS A  30
ILE A  79
 MN  A 201 (-2.5A)
MN  A 201 (-3.4A)
MN  A 201 (-3.4A)
None
 0.85A 1ei6C-6dk4A:
undetectable		 1ei6C-6dk4A:
10.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE1_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 6dk4 FERRIC UPTAKE
REGULATION PROTEIN
(Campylobacter
jejuni) 		3 / 3 ASP A  97
HIS A  86
HIS A  84
 MN  A 201 (-2.5A)
MN  A 201 (-3.3A)
MN  A 201 (-3.4A)
 0.52A 1oe1A-6dk4A:
undetectable		 1oe1A-6dk4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE3_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 6dk4 FERRIC UPTAKE
REGULATION PROTEIN
(Campylobacter
jejuni) 		3 / 3 ASP A  97
HIS A  86
HIS A  84
 MN  A 201 (-2.5A)
MN  A 201 (-3.3A)
MN  A 201 (-3.4A)
 0.51A 1oe3A-6dk4A:
undetectable		 1oe3A-6dk4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_E_GCSE710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 6dk4 FERRIC UPTAKE
REGULATION PROTEIN
(Campylobacter
jejuni) 		5 / 8 HIS A  86
ASP A  78
ILE A  79
HIS A  84
ASP A  97
 MN  A 201 (-3.3A)
MN  A 201 (-2.7A)
None
MN  A 201 (-3.4A)
MN  A 201 (-2.5A)
 1.43A 2xadA-6dk4A:
undetectable		 2xadA-6dk4A:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_F_GCSF710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 6dk4 FERRIC UPTAKE
REGULATION PROTEIN
(Campylobacter
jejuni) 		5 / 8 HIS A  86
ASP A  78
ILE A  79
HIS A  84
ASP A  97
 MN  A 201 (-3.3A)
MN  A 201 (-2.7A)
None
MN  A 201 (-3.4A)
MN  A 201 (-2.5A)
 1.47A 2xadB-6dk4A:
undetectable		 2xadB-6dk4A:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_G_GCSG710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 6dk4 FERRIC UPTAKE
REGULATION PROTEIN
(Campylobacter
jejuni) 		5 / 8 HIS A  86
ASP A  78
ILE A  79
HIS A  84
ASP A  97
 MN  A 201 (-3.3A)
MN  A 201 (-2.7A)
None
MN  A 201 (-3.4A)
MN  A 201 (-2.5A)
 1.44A 2xadC-6dk4A:
undetectable		 2xadC-6dk4A:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAD_H_GCSH710_1
(N-ACYL GLM
PEUDO-TEICOPLANIN
DEACETYLASE
TEICOPLANIN)		 6dk4 FERRIC UPTAKE
REGULATION PROTEIN
(Campylobacter
jejuni) 		5 / 8 HIS A  86
ASP A  78
ILE A  79
HIS A  84
ASP A  97
 MN  A 201 (-3.3A)
MN  A 201 (-2.7A)
None
MN  A 201 (-3.4A)
MN  A 201 (-2.5A)
 1.46A 2xadD-6dk4A:
undetectable		 2xadD-6dk4A:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_A_CUA1338_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 6dk4 FERRIC UPTAKE
REGULATION PROTEIN
(Campylobacter
jejuni) 		3 / 3 ASP A  97
HIS A  86
HIS A  84
 MN  A 201 (-2.5A)
MN  A 201 (-3.3A)
MN  A 201 (-3.4A)
 0.54A 2xxgA-6dk4A:
undetectable		 2xxgA-6dk4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_C_CUC1339_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 6dk4 FERRIC UPTAKE
REGULATION PROTEIN
(Campylobacter
jejuni) 		3 / 3 ASP A  97
HIS A  86
HIS A  84
 MN  A 201 (-2.5A)
MN  A 201 (-3.3A)
MN  A 201 (-3.4A)
 0.57A 2xxgC-6dk4A:
undetectable		 2xxgC-6dk4A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KCX_A_CQLA1_0
(HYPOXIA-INDUCIBLE
FACTOR 1-ALPHA
INHIBITOR)		 6dk4 FERRIC UPTAKE
REGULATION PROTEIN
(Campylobacter
jejuni) 		5 / 10 LEU A  25
HIS A  84
ASP A  97
ILE A  95
HIS A  86
 None
MN  A 201 (-3.4A)
MN  A 201 (-2.5A)
None
MN  A 201 (-3.3A)
 1.30A 3kcxA-6dk4A:
undetectable		 3kcxA-6dk4A:
undetectable