SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6dll'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A52_A_ESTA1_1
(ESTROGEN RECEPTOR)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		5 / 10 ALA A  59
GLU A  58
LEU A  20
ARG A 311
LEU A 109
 None
 1.41A 1a52A-6dllA:
undetectable		 1a52A-6dllA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A52_B_ESTB2_1
(ESTROGEN RECEPTOR)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		5 / 10 ALA A  59
GLU A  58
LEU A  20
ARG A 311
LEU A 109
 None
 1.43A 1a52B-6dllA:
undetectable		 1a52B-6dllA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB2_0
(ACTINOMYCIN D)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		3 / 3 THR A 217
PRO A 193
THR A 192
 None
 0.88A 1a7yB-6dllA:
undetectable		 1a7yB-6dllA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQE_A_FLPA1650_1
(PROTEIN
(PROSTAGLANDIN H2
SYNTHASE-1))		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		5 / 12 LEU A 325
ILE A 155
GLY A 157
ALA A 156
LEU A 309
 None
 1.00A 1cqeA-6dllA:
undetectable		 1cqeA-6dllA:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQE_B_FLPB2650_1
(PROTEIN
(PROSTAGLANDIN H2
SYNTHASE-1))		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		5 / 12 LEU A 325
ILE A 155
GLY A 157
ALA A 156
LEU A 309
 None
 0.99A 1cqeB-6dllA:
undetectable		 1cqeB-6dllA:
9.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC2_0
(ACTINOMYCIN D)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		3 / 3 THR A 217
PRO A 193
THR A 192
 None
 0.84A 1dscC-6dllA:
undetectable		 1dscC-6dllA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC8_0
(ACTINOMYCIN D)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		3 / 3 THR A 192
THR A 217
PRO A 193
 None
 0.73A 1dscC-6dllA:
undetectable		 1dscC-6dllA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_A_ESTA600_1
(ESTROGEN RECEPTOR)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		5 / 9 ALA A  59
GLU A  58
LEU A  20
ARG A 311
LEU A 109
 None
 1.35A 1ereA-6dllA:
undetectable		 1ereA-6dllA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_B_ESTB600_1
(ESTROGEN RECEPTOR)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		5 / 9 ALA A  59
GLU A  58
LEU A  20
ARG A 311
LEU A 109
 None
 1.37A 1ereB-6dllA:
undetectable		 1ereB-6dllA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_C_ESTC600_1
(ESTROGEN RECEPTOR)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		5 / 9 ALA A  59
GLU A  58
LEU A  20
ARG A 311
LEU A 109
 None
 1.35A 1ereC-6dllA:
undetectable		 1ereC-6dllA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_D_ESTD600_1
(ESTROGEN RECEPTOR)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		5 / 9 ALA A  59
GLU A  58
LEU A  20
ARG A 311
LEU A 109
 None
 1.37A 1ereD-6dllA:
undetectable		 1ereD-6dllA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_RALA600_1
(ESTROGEN RECEPTOR)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		5 / 12 GLU A  49
LEU A  48
LEU A 301
ARG A 335
ILE A 290
 CL  A 402 ( 4.6A)
None
CL  A 402 (-4.8A)
CL  A 402 (-3.5A)
None
 1.01A 1errA-6dllA:
undetectable		 1errA-6dllA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_C_DVAC8_0
(ACTINOMYCIN D)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		3 / 3 THR A 192
THR A 217
PRO A 193
 None
 0.83A 1fjaC-6dllA:
undetectable		 1fjaC-6dllA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_D_DVAD8_0
(ACTINOMYCIN D)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		3 / 3 THR A 192
THR A 217
PRO A 193
 None
 0.83A 1fjaD-6dllA:
undetectable		 1fjaD-6dllA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GWR_B_ESTB600_1
(OESTROGEN RECEPTOR)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		5 / 9 ALA A  59
GLU A  58
LEU A  20
ARG A 311
LEU A 109
 None
 1.40A 1gwrB-6dllA:
undetectable		 1gwrB-6dllA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1501_0
(FERROCHELATASE)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		5 / 12 ILE A 382
LEU A 247
PRO A 248
VAL A 251
VAL A  79
 None
 1.20A 1hrkA-6dllA:
undetectable		 1hrkA-6dllA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE8_0
(ACTINOMYCIN D)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		3 / 3 THR A 192
THR A 217
PRO A 193
 None
 0.87A 1i3wE-6dllA:
undetectable		 1i3wE-6dllA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG8_0
(ACTINOMYCIN D)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		3 / 3 THR A 192
THR A 217
PRO A 193
 None
 0.85A 1i3wG-6dllA:
undetectable		 1i3wG-6dllA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_H_DVAH8_0
(ACTINOMYCIN D)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		3 / 3 THR A 192
THR A 217
PRO A 193
 None
 0.86A 1i3wH-6dllA:
undetectable		 1i3wH-6dllA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD2_0
(ACTINOMYCIN D)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		3 / 3 THR A 217
PRO A 193
THR A 192
 None
 0.84A 1mnvD-6dllA:
undetectable		 1mnvD-6dllA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OVF_B_DVAB2_0
(ACTINOMYCIN D)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		3 / 3 THR A 217
PRO A 193
THR A 192
 None
 0.87A 1ovfB-6dllA:
undetectable		 1ovfB-6dllA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PBC_A_BHAA396_0
(P-HYDROXYBENZOATE
HYDROXYLASE)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		9 / 10 GLY A  46
VAL A  47
TRP A 185
LEU A 199
TYR A 201
LEU A 210
SER A 212
TYR A 222
ALA A 296
 None
None
None
None
None
None
None
FAD  A 401 (-4.3A)
FAD  A 401 ( 4.7A)
 0.36A 1pbcA-6dllA:
63.9		 1pbcA-6dllA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PBF_A_BHAA396_0
(P-HYDROXYBENZOATE
HYDROXYLASE)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		5 / 9 VAL A  47
LEU A 199
TYR A 201
SER A 212
ARG A 220
 None
 0.76A 1pbfA-6dllA:
64.1		 1pbfA-6dllA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PBF_A_BHAA396_0
(P-HYDROXYBENZOATE
HYDROXYLASE)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		7 / 9 VAL A  47
TRP A 185
LEU A 199
TYR A 201
LEU A 210
SER A 212
ALA A 296
 None
None
None
None
None
None
FAD  A 401 ( 4.7A)
 0.43A 1pbfA-6dllA:
64.1		 1pbfA-6dllA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PCG_B_ESTB2_1
(ESTROGEN RECEPTOR)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		5 / 10 ALA A  59
GLU A  58
LEU A  20
ARG A 311
LEU A 109
 None
 1.42A 1pcgB-6dllA:
undetectable		 1pcgB-6dllA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_A_ESTA600_1
(ESTRADIOL RECEPTOR)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		5 / 10 ALA A 296
GLU A  49
LEU A 301
ARG A 335
ILE A 290
 FAD  A 401 ( 4.7A)
CL  A 402 ( 4.6A)
CL  A 402 (-4.8A)
CL  A 402 (-3.5A)
None
 1.02A 1qkuA-6dllA:
undetectable		 1qkuA-6dllA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_B_ESTB600_1
(ESTRADIOL RECEPTOR)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		5 / 10 ALA A 296
GLU A  49
LEU A 301
ARG A 335
ILE A 290
 FAD  A 401 ( 4.7A)
CL  A 402 ( 4.6A)
CL  A 402 (-4.8A)
CL  A 402 (-3.5A)
None
 1.03A 1qkuB-6dllA:
undetectable		 1qkuB-6dllA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_C_ESTC600_1
(ESTRADIOL RECEPTOR)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		5 / 10 ALA A 296
GLU A  49
LEU A 301
ARG A 335
ILE A 290
 FAD  A 401 ( 4.7A)
CL  A 402 ( 4.6A)
CL  A 402 (-4.8A)
CL  A 402 (-3.5A)
None
 1.03A 1qkuC-6dllA:
undetectable		 1qkuC-6dllA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL8_0
(7-AMINO-ACTINOMYCIN
D)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		3 / 3 THR A 192
THR A 217
PRO A 193
 None
 0.86A 1unjL-6dllA:
undetectable		 1unjL-6dllA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR2_0
(7-AMINO-ACTINOMYCIN
D)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		3 / 3 THR A 217
PRO A 193
THR A 192
 None
 0.86A 1unjR-6dllA:
undetectable		 1unjR-6dllA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_W_DVAW8_0
(7-AMINO-ACTINOMYCIN
D)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		3 / 3 THR A 192
THR A 217
PRO A 193
 None
 0.80A 1unjW-6dllA:
undetectable		 1unjW-6dllA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE2_0
(7-AMINOACTINOMYCIN D)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		3 / 3 THR A 217
PRO A 193
THR A 192
 None
 0.85A 1unmE-6dllA:
undetectable		 1unmE-6dllA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE8_0
(7-AMINOACTINOMYCIN D)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		3 / 3 THR A 192
THR A 217
PRO A 193
 None
 0.84A 1unmE-6dllA:
undetectable		 1unmE-6dllA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF2_0
(7-AMINOACTINOMYCIN D)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		3 / 3 THR A 217
PRO A 193
THR A 192
 None
 0.87A 1unmF-6dllA:
undetectable		 1unmF-6dllA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AYL_B_FLPB2701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		5 / 12 LEU A 325
ILE A 155
GLY A 157
ALA A 156
LEU A 309
 None
 1.00A 2aylB-6dllA:
undetectable		 2aylB-6dllA:
10.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_A_SAMA2001_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		5 / 12 PHE A 282
LEU A 281
ALA A  10
CYH A 158
VAL A 284
 None
 1.45A 2g70A-6dllA:
undetectable		 2g70A-6dllA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_B_CHDB1605_0
(FERROCHELATASE)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		5 / 12 ILE A 382
LEU A 247
PRO A 248
VAL A 251
VAL A  79
 None
 1.24A 2hrcB-6dllA:
undetectable		 2hrcB-6dllA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_A_RALA600_1
(ESTROGEN RECEPTOR)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		5 / 12 GLU A  49
LEU A  48
LEU A 301
ARG A 335
ILE A 290
 CL  A 402 ( 4.6A)
None
CL  A 402 (-4.8A)
CL  A 402 (-3.5A)
None
 1.11A 2jfaA-6dllA:
undetectable		 2jfaA-6dllA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NPN_A_SAMA4633_0
(PUTATIVE COBALAMIN
SYNTHESIS RELATED
PROTEIN)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		5 / 9 GLY A 285
LEU A 301
ALA A 303
LEU A  16
THR A  52
 FAD  A 401 (-3.6A)
CL  A 402 (-4.8A)
None
None
None
 1.25A 2npnA-6dllA:
undetectable		 2npnA-6dllA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OCF_A_ESTA596_1
(ESTROGEN RECEPTOR)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		5 / 10 ALA A  59
GLU A  58
LEU A  20
ARG A 311
LEU A 109
 None
 1.50A 2ocfA-6dllA:
undetectable		 2ocfA-6dllA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_A_CHDA801_0
(FERROCHELATASE)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		5 / 12 LEU A 373
GLN A 365
LEU A 247
PRO A 248
VAL A 251
 None
 1.10A 2qd4A-6dllA:
undetectable		 2qd4A-6dllA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_A_ACHA1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		4 / 7 TYR A 138
CYH A 152
GLN A 128
ILE A 155
 None
 1.25A 2xz5A-6dllA:
undetectable
2xz5B-6dllA:
undetectable		 2xz5A-6dllA:
undetectable
2xz5B-6dllA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_E_ACHE1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		4 / 7 GLN A 128
ILE A 155
TYR A 138
CYH A 152
 None
 1.33A 2xz5D-6dllA:
undetectable
2xz5E-6dllA:
undetectable		 2xz5D-6dllA:
undetectable
2xz5E-6dllA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
316D_C_DVAC2_0
(8-FLUORO-ACTINOMYCIN
D)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		3 / 3 THR A 217
PRO A 193
THR A 192
 None
 0.84A 316dC-6dllA:
undetectable		 316dC-6dllA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BC9_A_ACRA901_1
(ALPHA AMYLASE,
CATALYTIC REGION)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		4 / 7 ASP A 229
SER A 264
TRP A 234
GLU A 262
 None
 1.10A 3bc9A-6dllA:
undetectable		 3bc9A-6dllA:
9.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		4 / 4 SER A  13
GLY A  14
GLY A 285
GLY A 160
 FAD  A 401 (-2.6A)
None
FAD  A 401 (-3.6A)
FAD  A 401 (-3.8A)
 0.88A 3bogB-6dllA:
undetectable
3bogD-6dllA:
undetectable		 3bogB-6dllA:
undetectable
3bogD-6dllA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_A_SAMA238_0
(N,N-DIMETHYLTRANSFER
ASE)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		5 / 12 ALA A  10
GLY A   9
SER A  13
MET A 110
LEU A  40
 None
FAD  A 401 (-3.4A)
FAD  A 401 (-2.6A)
None
None
 1.00A 3bxoA-6dllA:
2.2		 3bxoA-6dllA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ERD_B_DESB800_1
(ESTROGEN RECEPTOR
ALPHA)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		5 / 10 ALA A  59
GLU A  58
LEU A  20
ARG A 311
LEU A 109
 None
 1.43A 3erdB-6dllA:
undetectable		 3erdB-6dllA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWV_A_RFXA801_1
(TRANSPORTER)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		5 / 12 LEU A 281
GLY A 279
LEU A 132
ILE A 155
ASP A 151
 None
 0.99A 3gwvA-6dllA:
undetectable		 3gwvA-6dllA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWW_A_SFXA801_1
(TRANSPORTER)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		5 / 12 LEU A 281
GLY A 279
LEU A 132
ILE A 155
ASP A 151
 None
 1.04A 3gwwA-6dllA:
undetectable		 3gwwA-6dllA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HZN_D_ACTD229_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		4 / 4 ASP A 144
GLY A 145
LYS A 143
GLU A 142
 None
 1.28A 3hznD-6dllA:
undetectable		 3hznD-6dllA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9F_H_LFXH0_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		4 / 6 ARG A 214
ARG A  42
GLY A  41
GLU A  32
 None
FAD  A 401 (-2.9A)
None
FAD  A 401 (-2.7A)
 1.09A 3k9fA-6dllA:
undetectable
3k9fB-6dllA:
undetectable
3k9fD-6dllA:
undetectable		 3k9fA-6dllA:
10.51
3k9fB-6dllA:
10.51
3k9fD-6dllA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_A_CELA701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		5 / 12 VAL A 284
LEU A 309
SER A 168
ILE A   8
GLY A   9
 None
None
None
None
FAD  A 401 (-3.4A)
 1.12A 3kk6A-6dllA:
undetectable		 3kk6A-6dllA:
10.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_B_CELB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		5 / 12 VAL A 284
LEU A 309
SER A 168
ILE A   8
GLY A   9
 None
None
None
None
FAD  A 401 (-3.4A)
 1.11A 3kk6B-6dllA:
undetectable		 3kk6B-6dllA:
10.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_B_NIMB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		5 / 12 LEU A 325
ILE A 155
GLY A 157
ALA A 156
LEU A 309
 None
 1.02A 3n8xB-6dllA:
0.1		 3n8xB-6dllA:
10.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ6_A_SAMA300_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		5 / 12 LEU A 309
ILE A  26
ILE A   8
ASP A 153
LEU A 281
 None
 1.00A 3uj6A-6dllA:
undetectable		 3uj6A-6dllA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UUD_B_ESTB600_1
(ESTROGEN RECEPTOR)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		5 / 10 ALA A  59
GLU A  58
LEU A  20
ARG A 311
LEU A 109
 None
 1.38A 3uudB-6dllA:
undetectable		 3uudB-6dllA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V5W_A_8PRA701_2
(G-PROTEIN COUPLED
RECEPTOR KINASE 2)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		3 / 3 LEU A 139
MET A   1
ASP A  27
 None
 0.90A 3v5wA-6dllA:
undetectable		 3v5wA-6dllA:
7.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZW_A_SAMA1451_0
(WBDD)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		5 / 12 ALA A 125
GLN A 128
ASN A 126
ILE A 150
VAL A  31
 None
 1.20A 4azwA-6dllA:
undetectable		 4azwA-6dllA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QCK_A_ASDA404_1
(3-KETOSTEROID-9-ALPH
A-MONOOXYGENASE
OXYGENASE SUBUNIT)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		5 / 12 VAL A  31
LEU A 309
ALA A   6
LEU A 281
ASP A 159
 None
 1.26A 4qckA-6dllA:
undetectable		 4qckA-6dllA:
12.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XR4_B_AG2B511_1
(HOMOSPERMIDINE
SYNTHASE)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		3 / 3 VAL A 225
PHE A 239
ARG A 220
 None
 0.91A 4xr4B-6dllA:
2.7		 4xr4B-6dllA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZ8_A_GCSA208_1
(GLUCANASE/CHITOSANAS
E)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		4 / 7 GLU A  49
ARG A 335
ASP A 305
ALA A 303
 CL  A 402 ( 4.6A)
CL  A 402 (-3.5A)
None
None
 0.91A 4zz8A-6dllA:
undetectable		 4zz8A-6dllA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQF_A_CZEA613_1
(SERUM ALBUMIN)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		5 / 9 ALA A 156
ASP A 159
GLY A  14
LEU A  17
LEU A 309
 None
 1.21A 5dqfA-6dllA:
undetectable		 5dqfA-6dllA:
9.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DX3_A_ESTA601_1
(ESTROGEN RECEPTOR)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		5 / 10 ALA A  59
GLU A  58
LEU A  20
ARG A 311
GLY A  14
 None
 1.27A 5dx3A-6dllA:
undetectable		 5dx3A-6dllA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DX3_A_ESTA601_1
(ESTROGEN RECEPTOR)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		5 / 10 ALA A  59
GLU A  58
LEU A  20
ARG A 311
LEU A 109
 None
 1.39A 5dx3A-6dllA:
undetectable		 5dx3A-6dllA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DX3_B_ESTB1000_1
(ESTROGEN RECEPTOR)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		5 / 9 ALA A  59
GLU A  58
LEU A  20
ARG A 311
LEU A 109
 None
 1.43A 5dx3B-6dllA:
undetectable		 5dx3B-6dllA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXB_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		5 / 10 ALA A  59
GLU A  58
LEU A  20
ARG A 311
GLY A  14
 None
 1.32A 5dxbA-6dllA:
undetectable		 5dxbA-6dllA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXE_B_ESTB1000_1
(ESTROGEN RECEPTOR)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		5 / 10 ALA A  59
GLU A  58
LEU A  20
ARG A 311
LEU A 109
 None
 1.43A 5dxeB-6dllA:
undetectable		 5dxeB-6dllA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G48_A_1FLA1375_1
(DNA POLYMERASE III
SUBUNIT BETA)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		4 / 8 PRO A 275
ILE A 169
PRO A 129
LEU A 132
 None
 0.91A 5g48A-6dllA:
undetectable		 5g48A-6dllA:
12.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HYR_A_ESTA601_1
(ESTROGEN RECEPTOR)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		5 / 10 ALA A  59
GLU A  58
LEU A  20
ARG A 311
LEU A 109
 None
 1.40A 5hyrA-6dllA:
undetectable		 5hyrA-6dllA:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HYR_B_ESTB601_1
(ESTROGEN RECEPTOR)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		5 / 11 ALA A  59
GLU A  58
LEU A  20
ARG A 311
LEU A 109
 None
 1.40A 5hyrB-6dllA:
undetectable		 5hyrB-6dllA:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		4 / 4 GLN A   4
THR A   3
LEU A  17
LEU A  21
 None
 1.20A 5m5kB-6dllA:
2.6		 5m5kB-6dllA:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WGD_A_ESTA601_1
(ESTROGEN RECEPTOR)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		5 / 9 ALA A  59
GLU A  58
LEU A  20
ARG A 311
LEU A 109
 None
 1.42A 5wgdA-6dllA:
undetectable		 5wgdA-6dllA:
24.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WGQ_A_ESTA601_1
(ESTROGEN RECEPTOR)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		5 / 9 ALA A  59
GLU A  58
LEU A  20
ARG A 311
GLY A  14
 None
 1.29A 5wgqA-6dllA:
undetectable		 5wgqA-6dllA:
24.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WGQ_A_ESTA601_1
(ESTROGEN RECEPTOR)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		5 / 9 ALA A  59
GLU A  58
LEU A  20
ARG A 311
LEU A 109
 None
 1.40A 5wgqA-6dllA:
undetectable		 5wgqA-6dllA:
24.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WGQ_B_ESTB601_1
(ESTROGEN RECEPTOR)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		5 / 10 ALA A  59
GLU A  58
LEU A  20
ARG A 311
LEU A 109
 None
 1.42A 5wgqB-6dllA:
undetectable		 5wgqB-6dllA:
24.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBZ_B_ESTB602_1
(ESTROGEN RECEPTOR)		 6dll P-HYDROXYBENZOATE
HYDROXYLASE
(Pseudomonas
putida) 		5 / 10 ALA A  59
GLU A  58
LEU A  20
ARG A 311
LEU A 109
 None
 1.42A 6cbzB-6dllA:
undetectable		 6cbzB-6dllA:
23.86