SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6dnh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_C_NCAC1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 6dnh PRE-MRNA 3' END
PROCESSING PROTEIN
WDR33
(Homo
sapiens) 		4 / 6 ARG B 227
SER B 221
ARG B 241
GLU B 203
 None
 1.47A 2c8aC-6dnhB:
undetectable		 2c8aC-6dnhB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X1L_A_ADNA601_1
(METHIONYL-TRNA
SYNTHETASE)		 6dnh PRE-MRNA 3' END
PROCESSING PROTEIN
WDR33
(Homo
sapiens) 		5 / 11 ALA B 336
ALA B 338
GLY B 351
ILE B 378
HIS B 330
 None
 1.10A 2x1lA-6dnhB:
undetectable		 2x1lA-6dnhB:
8.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X1L_C_ADNC601_1
(METHIONYL-TRNA
SYNTHETASE)		 6dnh PRE-MRNA 3' END
PROCESSING PROTEIN
WDR33
(Homo
sapiens) 		5 / 11 ALA B 336
ALA B 338
GLY B 351
ILE B 378
HIS B 330
 None
 1.04A 2x1lC-6dnhB:
undetectable		 2x1lC-6dnhB:
8.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YK1_H_NCTH300_1
(FAB FRAGMENT, HEAVY
CHAIN
FAB FRAGMENT, LIGHT
CHAIN)		 6dnh PRE-MRNA 3' END
PROCESSING PROTEIN
WDR33
(Homo
sapiens) 		5 / 10 GLY B 393
SER B 392
TYR B 415
ALA B 373
TRP B 402
 None
 1.48A 2yk1H-6dnhB:
undetectable
2yk1L-6dnhB:
undetectable		 2yk1H-6dnhB:
13.88
2yk1L-6dnhB:
13.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_3
(PHOSPHOLIPASE A2)		 6dnh PRE-MRNA 3' END
PROCESSING PROTEIN
WDR33
(Homo
sapiens) 		4 / 7 VAL B 125
ILE B 378
GLY B 351
ARG B 308
 None
 0.90A 3bjwF-6dnhB:
undetectable		 3bjwF-6dnhB:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DHID8_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 6dnh PRE-MRNA 3' END
PROCESSING PROTEIN
WDR33
(Homo
sapiens) 		4 / 4 SER B 263
GLY B 262
GLY B 244
GLY B 224
 None
 0.91A 3bogB-6dnhB:
undetectable
3bogD-6dnhB:
undetectable		 3bogB-6dnhB:
undetectable
3bogD-6dnhB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4POO_A_SAMA301_0
(PUTATIVE RNA
METHYLASE)		 6dnh PRE-MRNA 3' END
PROCESSING PROTEIN
WDR33
(Homo
sapiens) 		5 / 12 GLY B 393
ASP B 396
SER B 349
ASN B 395
THR B 335
 None
 1.02A 4pooA-6dnhB:
undetectable		 4pooA-6dnhB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B6I_A_ADNA302_1
(FLUORINASE)		 6dnh PRE-MRNA 3' END
PROCESSING PROTEIN
WDR33
(Homo
sapiens) 		4 / 7 TRP B 229
THR B 219
THR B 225
SER B 221
 None
 1.31A 5b6iA-6dnhB:
undetectable		 5b6iA-6dnhB:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B6I_B_ADNB302_1
(FLUORINASE)		 6dnh PRE-MRNA 3' END
PROCESSING PROTEIN
WDR33
(Homo
sapiens) 		4 / 6 TRP B 229
THR B 219
THR B 225
SER B 221
 None
 1.33A 5b6iB-6dnhB:
undetectable		 5b6iB-6dnhB:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Q_BEZQ801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 6dnh PRE-MRNA 3' END
PROCESSING PROTEIN
WDR33
(Homo
sapiens) 		4 / 5 SER B 349
ALA B 336
HIS B 330
LEU B 356
 None
 1.45A 5dzkc-6dnhB:
undetectable
5dzkq-6dnhB:
undetectable		 5dzkc-6dnhB:
undetectable
5dzkq-6dnhB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_A_PAUA602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 6dnh PRE-MRNA 3' END
PROCESSING PROTEIN
WDR33
(Homo
sapiens) 		4 / 7 GLY B 350
SER B 355
GLY B 354
ALA B 334
 None
 0.84A 5e26A-6dnhB:
undetectable
5e26B-6dnhB:
undetectable		 5e26A-6dnhB:
undetectable
5e26B-6dnhB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_D_PAUD601_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 6dnh PRE-MRNA 3' END
PROCESSING PROTEIN
WDR33
(Homo
sapiens) 		4 / 8 ALA B 334
GLY B 350
SER B 355
GLY B 354
 None
 0.84A 5e26C-6dnhB:
undetectable
5e26D-6dnhB:
undetectable		 5e26C-6dnhB:
undetectable
5e26D-6dnhB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MAF_A_XINA403_2
(MATERNAL EMBRYONIC
LEUCINE ZIPPER
KINASE)		 6dnh CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 4
(Homo
sapiens) 		4 / 5 LEU C  28
CYH C  55
CYH C  49
ASP C  80
 None
ZN  C 301 (-2.8A)
ZN  C 301 (-2.4A)
None
 1.26A 5mafA-6dnhC:
undetectable		 5mafA-6dnhC:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NN8_A_ACRA1016_1
(LYSOSOMAL
ALPHA-GLUCOSIDASE)		 6dnh CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 4
(Homo
sapiens) 		4 / 5 ASP C  34
GLY C  37
TRP C  71
CYH C  76
 None
None
None
ZN  C 302 (-2.4A)
 1.18A 5nn8A-6dnhC:
undetectable		 5nn8A-6dnhC:
7.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_A_EY4A501_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 6dnh PRE-MRNA 3' END
PROCESSING PROTEIN
WDR33
(Homo
sapiens) 		4 / 5 VAL B 260
TRP B 273
PRO B 275
THR B 283
 None
 1.38A 6cduA-6dnhB:
undetectable
6cduB-6dnhB:
undetectable		 6cduA-6dnhB:
undetectable
6cduB-6dnhB:
undetectable