SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6du8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT3_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 6du8 -
(-) 		4 / 7 LEU A 294
LEU A 288
LEU A 200
GLN A 202
 None
 0.90A 1kt3A-6du8A:
undetectable		 1kt3A-6du8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_B_ADNB1502_1
(CLASS B ACID
PHOSPHATASE)		 6du8 -
(-) 		4 / 7 GLU A 252
LEU A 253
THR A 246
TYR A 247
 None
 1.04A 1rmtB-6du8A:
undetectable		 1rmtB-6du8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRE_B_CHDB701_0
(FERROCHELATASE)		 6du8 -
(-) 		3 / 3 LYS A 204
GLY A 238
PRO A 239
 None
 0.90A 2hreB-6du8A:
undetectable		 2hreB-6du8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		 6du8 -
(-) 		4 / 6 ALA A 287
LEU A 288
ALA A 244
THR A 243
 None
 0.92A 3b6hA-6du8A:
undetectable		 3b6hA-6du8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_C_CGEC501_1
(CYTOCHROME P450 2B4)		 6du8 -
(-) 		5 / 9 VAL A 548
PHE A 547
PHE A 517
ILE A 520
PHE A 488
 None
 1.16A 3me6C-6du8A:
undetectable		 3me6C-6du8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_D_CGED501_1
(CYTOCHROME P450 2B4)		 6du8 -
(-) 		5 / 9 VAL A 548
PHE A 547
PHE A 517
ILE A 520
PHE A 488
 None
 1.18A 3me6D-6du8A:
undetectable		 3me6D-6du8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DZ2_A_FK5A200_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 6du8 -
(-) 		5 / 11 TYR A 366
PHE A 362
VAL A 109
ILE A 108
ILE A 453
 None
 1.41A 4dz2A-6du8A:
undetectable
4dz2B-6du8A:
undetectable		 4dz2A-6du8A:
undetectable
4dz2B-6du8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DZ2_B_FK5B200_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 6du8 -
(-) 		5 / 11 TYR A 366
PHE A 362
VAL A 109
ILE A 108
ILE A 453
 None
 1.38A 4dz2A-6du8A:
undetectable
4dz2B-6du8A:
undetectable		 4dz2A-6du8A:
undetectable
4dz2B-6du8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DZ3_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 6du8 -
(-) 		5 / 10 TYR A 366
PHE A 362
VAL A 109
ILE A 108
ILE A 453
 None
 1.37A 4dz3A-6du8A:
undetectable		 4dz3A-6du8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DZ3_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 6du8 -
(-) 		5 / 10 TYR A 366
PHE A 362
VAL A 109
ILE A 108
ILE A 453
 None
 1.36A 4dz3B-6du8A:
undetectable		 4dz3B-6du8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NNR_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP2)		 6du8 -
(-) 		5 / 10 TYR A 366
PHE A 362
VAL A 109
ILE A 108
ILE A 453
 None
 1.43A 4nnrB-6du8A:
undetectable		 4nnrB-6du8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1F_A_3WFA501_1
(NUCLEAR RECEPTOR
SUBFAMILY 1 GROUP I
MEMBER 2)		 6du8 -
(-) 		5 / 12 ASP A 304
LEU A 165
SER A 281
LEU A 200
ILE A 303
 None
 1.13A 4x1fA-6du8A:
undetectable		 4x1fA-6du8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1G_A_3WFA501_1
(NUCLEAR RECEPTOR
SUBFAMILY 1 GROUP I
MEMBER 2)		 6du8 -
(-) 		6 / 12 ASP A 304
SER A 306
LEU A 165
SER A 281
LEU A 200
ILE A 303
 None
 1.30A 4x1gA-6du8A:
undetectable		 4x1gA-6du8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HS6_A_J3ZA302_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE 14)		 6du8 -
(-) 		4 / 8 GLN A 202
LEU A 285
TRP A 158
LEU A 288
 None
 1.11A 5hs6A-6du8A:
undetectable		 5hs6A-6du8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BP4_A_SAMA505_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-9 SPECIFIC)		 6du8 -
(-) 		3 / 3 ILE A 363
ASN A 445
CYH A 115
 None
 0.84A 6bp4A-6du8A:
undetectable		 6bp4A-6du8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_A_Y00A406_1
(BETA-1 ADRENERGIC
RECEPTOR)		 6du8 -
(-) 		4 / 6 VAL A 548
PHE A 517
PHE A 488
PHE A 484
 None
 0.96A 6h7lA-6du8A:
3.6		 6h7lA-6du8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_1
(BETA-1 ADRENERGIC
RECEPTOR)		 6du8 -
(-) 		4 / 6 VAL A 548
PHE A 517
PHE A 488
PHE A 484
 None
 0.96A 6h7lB-6du8A:
3.4		 6h7lB-6du8A:
undetectable