SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6dus'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M2Z_D_DEXD401_1
(GLUCOCORTICOID
RECEPTOR)		 6dus TYPE III SECRETION
SYSTEM EFFECTOR
PROTEIN
(Salmonella
enterica) 		5 / 12 ASN A 259
ARG A 184
MET A 279
CYH A 293
ILE A 262
 NAG  A 502 (-3.2A)
None
None
None
None
 1.39A 1m2zD-6dusA:
undetectable		 1m2zD-6dusA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_B_DEXB2999_1
(GLUCOCORTICOID
RECEPTOR)		 6dus TYPE III SECRETION
SYSTEM EFFECTOR
PROTEIN
(Salmonella
enterica) 		5 / 12 ASN A 259
ARG A 184
MET A 279
CYH A 293
ILE A 262
 NAG  A 502 (-3.2A)
None
None
None
None
 1.44A 1p93B-6dusA:
undetectable		 1p93B-6dusA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_D_DEXD4999_1
(GLUCOCORTICOID
RECEPTOR)		 6dus TYPE III SECRETION
SYSTEM EFFECTOR
PROTEIN
(Salmonella
enterica) 		5 / 12 ASN A 259
ARG A 184
MET A 279
CYH A 293
ILE A 262
 NAG  A 502 (-3.2A)
None
None
None
None
 1.37A 1p93D-6dusA:
undetectable		 1p93D-6dusA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EBZ_B_017B201_2
(PROTEASE)		 6dus TYPE III SECRETION
SYSTEM EFFECTOR
PROTEIN
(Salmonella
enterica) 		5 / 11 LEU A  76
ALA A 227
ASP A 226
ASP A 228
ILE A  80
 MPD  A 506 ( 4.9A)
UDP  A 501 (-3.8A)
UDP  A 501 (-3.4A)
MG  A 503 ( 2.4A)
MPD  A 506 (-4.5A)
 1.14A 3ebzB-6dusA:
undetectable		 3ebzB-6dusA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MNO_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 6dus TYPE III SECRETION
SYSTEM EFFECTOR
PROTEIN
(Salmonella
enterica) 		5 / 12 ASN A 259
ARG A 184
MET A 279
CYH A 293
ILE A 262
 NAG  A 502 (-3.2A)
None
None
None
None
 1.35A 3mnoA-6dusA:
undetectable		 3mnoA-6dusA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		 6dus TYPE III SECRETION
SYSTEM EFFECTOR
PROTEIN
(Salmonella
enterica) 		5 / 10 ILE A  65
VAL A  93
TYR A 114
ILE A  80
ILE A  79
 None
None
None
MPD  A 506 (-4.5A)
None
 0.98A 3p4wD-6dusA:
undetectable		 3p4wD-6dusA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_E_DSFE319_1
(GLR4197 PROTEIN)		 6dus TYPE III SECRETION
SYSTEM EFFECTOR
PROTEIN
(Salmonella
enterica) 		5 / 10 ILE A  65
VAL A  93
TYR A 114
ILE A  80
ILE A  79
 None
None
None
MPD  A 506 (-4.5A)
None
 0.98A 3p4wE-6dusA:
undetectable		 3p4wE-6dusA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_B_ACRB701_1
(ALPHA-GLUCOSIDASE)		 6dus TYPE III SECRETION
SYSTEM EFFECTOR
PROTEIN
(Salmonella
enterica) 		5 / 12 ASP A 191
ILE A 289
ASP A 325
ARG A 194
HIS A 247
 NAG  A 502 (-2.9A)
None
MG  A 503 ( 2.9A)
NAG  A 502 ( 4.5A)
None
 1.28A 3phaB-6dusA:
undetectable		 3phaB-6dusA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_C_ACRC701_1
(ALPHA-GLUCOSIDASE)		 6dus TYPE III SECRETION
SYSTEM EFFECTOR
PROTEIN
(Salmonella
enterica) 		5 / 12 ASP A 191
ILE A 289
ASP A 325
ARG A 194
HIS A 247
 NAG  A 502 (-2.9A)
None
MG  A 503 ( 2.9A)
NAG  A 502 ( 4.5A)
None
 1.32A 3phaC-6dusA:
undetectable		 3phaC-6dusA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_D_ACRD701_1
(ALPHA-GLUCOSIDASE)		 6dus TYPE III SECRETION
SYSTEM EFFECTOR
PROTEIN
(Salmonella
enterica) 		5 / 12 ASP A 191
ILE A 289
ASP A 325
ARG A 194
HIS A 247
 NAG  A 502 (-2.9A)
None
MG  A 503 ( 2.9A)
NAG  A 502 ( 4.5A)
None
 1.31A 3phaD-6dusA:
undetectable		 3phaD-6dusA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA804_1
(CATALASE-PEROXIDASE)		 6dus TYPE III SECRETION
SYSTEM EFFECTOR
PROTEIN
(Salmonella
enterica) 		3 / 3 ASN A  56
GLU A  54
ARG A  55
 None
UDP  A 501 (-4.9A)
None
 1.06A 3wxoA-6dusA:
undetectable		 3wxoA-6dusA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MGH_A_ACTA1320_0
(PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE)		 6dus TYPE III SECRETION
SYSTEM EFFECTOR
PROTEIN
(Salmonella
enterica) 		4 / 5 VAL A 246
LEU A 296
ILE A 244
LEU A 240
 None
 0.75A 4mghA-6dusA:
undetectable		 4mghA-6dusA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_C_ADNC401_2
(ADENOSINE KINASE)		 6dus TYPE III SECRETION
SYSTEM EFFECTOR
PROTEIN
(Salmonella
enterica) 		4 / 5 LEU A 329
SER A 327
LEU A 230
ASN A  78
 MPD  A 507 ( 4.7A)
MG  A 503 ( 2.2A)
MPD  A 507 (-4.9A)
None
 1.07A 4n09C-6dusA:
undetectable		 4n09C-6dusA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z69_A_DIFA1006_1
(SERUM ALBUMIN)		 6dus TYPE III SECRETION
SYSTEM EFFECTOR
PROTEIN
(Salmonella
enterica) 		4 / 7 ILE A 322
HIS A 319
GLY A 233
LYS A 234
 None
 1.01A 4z69A-6dusA:
2.5		 4z69A-6dusA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_C_AQ4C602_0
(CYTOCHROME P450 1A1)		 6dus TYPE III SECRETION
SYSTEM EFFECTOR
PROTEIN
(Salmonella
enterica) 		5 / 12 LEU A 125
PHE A 197
GLY A  92
ILE A  67
LEU A 107
 None
 1.16A 6dwnC-6dusA:
undetectable		 6dwnC-6dusA:
undetectable