SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6dxp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2501_0
(FERROCHELATASE)
6dxp -
(-)
5 / 12 LEU A 104
PHE A 108
LEU A   7
VAL A   4
VAL A 168
None
1.35A 1hrkB-6dxpA:
3.5
1hrkB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2R_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)
6dxp -
(-)
4 / 7 ARG A 157
VAL A 152
PHE A 170
GLU A 174
None
1.44A 1k2rA-6dxpA:
undetectable
1k2rB-6dxpA:
undetectable
1k2rA-6dxpA:
undetectable
1k2rB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2R_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)
6dxp -
(-)
4 / 7 PHE A 170
GLU A 174
ARG A 157
VAL A 152
None
1.40A 1k2rA-6dxpA:
undetectable
1k2rB-6dxpA:
undetectable
1k2rA-6dxpA:
undetectable
1k2rB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMW_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 PHE A 170
GLU A 174
ARG A 157
VAL A 152
None
1.41A 1mmwA-6dxpA:
undetectable
1mmwB-6dxpA:
undetectable
1mmwA-6dxpA:
undetectable
1mmwB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM4_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 ARG A 157
VAL A 152
PHE A 170
GLU A 174
None
1.43A 1om4A-6dxpA:
undetectable
1om4B-6dxpA:
undetectable
1om4A-6dxpA:
undetectable
1om4B-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM4_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 PHE A 170
GLU A 174
ARG A 157
VAL A 152
None
1.44A 1om4A-6dxpA:
undetectable
1om4B-6dxpA:
undetectable
1om4A-6dxpA:
undetectable
1om4B-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM5_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 8 ARG A 157
VAL A 152
PHE A 170
GLU A 174
None
1.40A 1om5A-6dxpA:
undetectable
1om5B-6dxpA:
undetectable
1om5A-6dxpA:
undetectable
1om5B-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6I_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 PHE A 170
GLU A 174
ARG A 157
VAL A 152
None
1.41A 1p6iA-6dxpA:
undetectable
1p6iB-6dxpA:
undetectable
1p6iA-6dxpA:
undetectable
1p6iB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 6 ARG A 157
VAL A 152
PHE A 170
GLU A 174
None
1.42A 1rs6A-6dxpA:
undetectable
1rs6B-6dxpA:
undetectable
1rs6A-6dxpA:
undetectable
1rs6B-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6H_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 8 ARG A 157
VAL A 152
PHE A 170
GLU A 174
None
1.42A 2g6hA-6dxpA:
undetectable
2g6hB-6dxpA:
undetectable
2g6hA-6dxpA:
undetectable
2g6hB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6H_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 6 PHE A 170
GLU A 174
ARG A 157
VAL A 152
None
1.41A 2g6hA-6dxpA:
undetectable
2g6hB-6dxpA:
undetectable
2g6hA-6dxpA:
undetectable
2g6hB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6K_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 ARG A 157
VAL A 152
PHE A 170
GLU A 174
None
1.41A 2g6kA-6dxpA:
undetectable
2g6kB-6dxpA:
undetectable
2g6kA-6dxpA:
undetectable
2g6kB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6K_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 PHE A 170
GLU A 174
ARG A 157
VAL A 152
None
1.42A 2g6kA-6dxpA:
undetectable
2g6kB-6dxpA:
undetectable
2g6kA-6dxpA:
undetectable
2g6kB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6M_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 ARG A 157
VAL A 152
PHE A 170
GLU A 174
None
1.41A 2g6mA-6dxpA:
undetectable
2g6mB-6dxpA:
undetectable
2g6mA-6dxpA:
undetectable
2g6mB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6M_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 PHE A 170
GLU A 174
ARG A 157
VAL A 152
None
1.43A 2g6mA-6dxpA:
undetectable
2g6mB-6dxpA:
undetectable
2g6mA-6dxpA:
undetectable
2g6mB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)
6dxp -
(-)
5 / 11 LEU A 104
PHE A 108
LEU A   7
VAL A   4
VAL A 168
None
1.32A 2po5B-6dxpA:
2.5
2po5B-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_D_DVAD10_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)
6dxp -
(-)
3 / 3 GLY A 127
GLY A 161
GLY A 164
None
0.32A 3bogD-6dxpA:
undetectable
3bogD-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_C_DXCC576_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)
6dxp -
(-)
4 / 8 PRO A  54
ALA A  58
ALA A  62
ILE A  69
None
0.78A 3dtuC-6dxpA:
undetectable
3dtuD-6dxpA:
undetectable
3dtuC-6dxpA:
undetectable
3dtuD-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 ARG A 157
VAL A 152
PHE A 170
GLU A 174
None
1.42A 3fc5A-6dxpA:
undetectable
3fc5B-6dxpA:
undetectable
3fc5A-6dxpA:
undetectable
3fc5B-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC5_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 PHE A 170
GLU A 174
ARG A 157
VAL A 152
None
1.41A 3fc5A-6dxpA:
undetectable
3fc5B-6dxpA:
undetectable
3fc5A-6dxpA:
undetectable
3fc5B-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 ARG A 157
VAL A 152
PHE A 170
GLU A 174
None
1.48A 3hsnA-6dxpA:
undetectable
3hsnB-6dxpA:
undetectable
3hsnA-6dxpA:
undetectable
3hsnB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSN_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 PHE A 170
GLU A 174
ARG A 157
VAL A 152
None
1.43A 3hsnA-6dxpA:
undetectable
3hsnB-6dxpA:
undetectable
3hsnA-6dxpA:
undetectable
3hsnB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSO_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 PHE A 170
GLU A 174
ARG A 157
VAL A 152
None
1.40A 3hsoA-6dxpA:
undetectable
3hsoB-6dxpA:
undetectable
3hsoA-6dxpA:
undetectable
3hsoB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSP_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 PHE A 170
GLU A 174
ARG A 157
VAL A 152
None
1.42A 3hspA-6dxpA:
undetectable
3hspB-6dxpA:
undetectable
3hspA-6dxpA:
undetectable
3hspB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 PHE A 170
GLU A 174
ARG A 157
VAL A 152
None
1.38A 3jt3A-6dxpA:
undetectable
3jt3B-6dxpA:
undetectable
3jt3A-6dxpA:
undetectable
3jt3B-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 PHE A 170
GLU A 174
ARG A 157
VAL A 152
None
1.41A 3jt4A-6dxpA:
undetectable
3jt4B-6dxpA:
undetectable
3jt4A-6dxpA:
undetectable
3jt4B-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 ARG A 157
VAL A 152
PHE A 170
GLU A 174
None
1.46A 3jt5A-6dxpA:
undetectable
3jt5B-6dxpA:
undetectable
3jt5A-6dxpA:
undetectable
3jt5B-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 PHE A 170
GLU A 174
ARG A 157
VAL A 152
None
1.42A 3jt5A-6dxpA:
undetectable
3jt5B-6dxpA:
undetectable
3jt5A-6dxpA:
undetectable
3jt5B-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 PHE A 170
GLU A 174
ARG A 157
VAL A 152
None
1.39A 3jt6A-6dxpA:
undetectable
3jt6B-6dxpA:
undetectable
3jt6A-6dxpA:
undetectable
3jt6B-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT9_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 PHE A 170
GLU A 174
ARG A 157
VAL A 152
None
1.39A 3jt9A-6dxpA:
undetectable
3jt9B-6dxpA:
undetectable
3jt9A-6dxpA:
undetectable
3jt9B-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JTA_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 PHE A 170
GLU A 174
ARG A 157
VAL A 152
None
1.37A 3jtaA-6dxpA:
undetectable
3jtaB-6dxpA:
undetectable
3jtaA-6dxpA:
undetectable
3jtaB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2R_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)
6dxp -
(-)
4 / 7 ARG A 157
VAL A 152
PHE A 170
GLU A 174
None
1.43A 3n2rA-6dxpA:
undetectable
3n2rB-6dxpA:
undetectable
3n2rA-6dxpA:
undetectable
3n2rB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5V_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)
6dxp -
(-)
4 / 7 PHE A 170
GLU A 174
ARG A 157
VAL A 152
None
1.41A 3n5vA-6dxpA:
undetectable
3n5vB-6dxpA:
undetectable
3n5vA-6dxpA:
undetectable
3n5vB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 PHE A 170
GLU A 174
ARG A 157
VAL A 152
None
1.40A 3nlmA-6dxpA:
undetectable
3nlmB-6dxpA:
undetectable
3nlmA-6dxpA:
undetectable
3nlmB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 PHE A 170
GLU A 174
ARG A 157
VAL A 152
None
1.37A 3nloA-6dxpA:
undetectable
3nloB-6dxpA:
undetectable
3nloA-6dxpA:
undetectable
3nloB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 ARG A 157
VAL A 152
PHE A 170
GLU A 174
None
1.46A 3nlvA-6dxpA:
undetectable
3nlvB-6dxpA:
undetectable
3nlvA-6dxpA:
undetectable
3nlvB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU9_A_478A401_2
(PROTEASE)
6dxp -
(-)
5 / 10 LEU A  38
ASP A  36
GLY A  35
VAL A   6
VAL A   4
None
1.14A 3nu9B-6dxpA:
undetectable
3nu9B-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q99_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 PHE A 170
GLU A 174
ARG A 157
VAL A 152
None
1.39A 3q99A-6dxpA:
undetectable
3q99B-6dxpA:
undetectable
3q99A-6dxpA:
undetectable
3q99B-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q9A_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 ARG A 157
VAL A 152
PHE A 170
GLU A 174
None
1.43A 3q9aA-6dxpA:
undetectable
3q9aB-6dxpA:
undetectable
3q9aA-6dxpA:
undetectable
3q9aB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q9A_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 PHE A 170
GLU A 174
ARG A 157
VAL A 152
None
1.43A 3q9aA-6dxpA:
undetectable
3q9aB-6dxpA:
undetectable
3q9aA-6dxpA:
undetectable
3q9aB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 ARG A 157
VAL A 152
PHE A 170
GLU A 174
None
1.42A 3tylA-6dxpA:
undetectable
3tylB-6dxpA:
undetectable
3tylA-6dxpA:
undetectable
3tylB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 PHE A 170
GLU A 174
ARG A 157
VAL A 152
None
1.38A 3tymA-6dxpA:
undetectable
3tymB-6dxpA:
undetectable
3tymA-6dxpA:
undetectable
3tymB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 PHE A 170
GLU A 174
ARG A 157
VAL A 152
None
1.41A 3tynA-6dxpA:
undetectable
3tynB-6dxpA:
undetectable
3tynA-6dxpA:
undetectable
3tynB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 ARG A 157
VAL A 152
PHE A 170
GLU A 174
None
1.45A 3ufoA-6dxpA:
undetectable
3ufoB-6dxpA:
undetectable
3ufoA-6dxpA:
undetectable
3ufoB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 ARG A 157
VAL A 152
PHE A 170
GLU A 174
None
1.43A 3ufsA-6dxpA:
undetectable
3ufsB-6dxpA:
undetectable
3ufsA-6dxpA:
undetectable
3ufsB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UY4_A_PAUA302_0
(PANTOTHENATE
SYNTHETASE)
6dxp -
(-)
4 / 8 ARG A 133
VAL A  90
VAL A 137
ASP A  36
None
1.16A 3uy4A-6dxpA:
undetectable
3uy4A-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)
6dxp -
(-)
5 / 12 LEU A 104
PHE A 108
LEU A   7
VAL A   4
VAL A 168
None
1.31A 3w1wB-6dxpA:
3.3
3w1wB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C39_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 ARG A 157
VAL A 152
PHE A 170
GLU A 174
None
1.42A 4c39A-6dxpA:
undetectable
4c39B-6dxpA:
undetectable
4c39A-6dxpA:
undetectable
4c39B-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTW_B_H4BB1720_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 PHE A 170
GLU A 174
ARG A 157
VAL A 152
None
1.43A 4ctwA-6dxpA:
undetectable
4ctwB-6dxpA:
undetectable
4ctwA-6dxpA:
undetectable
4ctwB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTX_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 PHE A 170
GLU A 174
ARG A 157
VAL A 152
None
1.41A 4ctxA-6dxpA:
undetectable
4ctxB-6dxpA:
undetectable
4ctxA-6dxpA:
undetectable
4ctxB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 ARG A 157
VAL A 152
PHE A 170
GLU A 174
None
1.48A 4d1nA-6dxpA:
undetectable
4d1nB-6dxpA:
undetectable
4d1nA-6dxpA:
undetectable
4d1nB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_C_H4BC760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 ARG A 157
VAL A 152
PHE A 170
GLU A 174
None
1.42A 4d1nC-6dxpA:
undetectable
4d1nD-6dxpA:
undetectable
4d1nC-6dxpA:
undetectable
4d1nD-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_D_H4BD760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 6 PHE A 170
GLU A 174
ARG A 157
VAL A 152
None
1.44A 4d1nC-6dxpA:
undetectable
4d1nD-6dxpA:
undetectable
4d1nC-6dxpA:
undetectable
4d1nD-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D30_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 PHE A 170
GLU A 174
ARG A 157
VAL A 152
None
1.40A 4d30A-6dxpA:
undetectable
4d30B-6dxpA:
undetectable
4d30A-6dxpA:
undetectable
4d30B-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D32_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 ARG A 157
VAL A 152
PHE A 170
GLU A 174
None
1.37A 4d32A-6dxpA:
undetectable
4d32B-6dxpA:
undetectable
4d32A-6dxpA:
undetectable
4d32B-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 ARG A 157
VAL A 152
PHE A 170
GLU A 174
None
1.44A 4fvwA-6dxpA:
undetectable
4fvwB-6dxpA:
undetectable
4fvwA-6dxpA:
undetectable
4fvwB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 PHE A 170
GLU A 174
ARG A 157
VAL A 152
None
1.40A 4fvwA-6dxpA:
undetectable
4fvwB-6dxpA:
undetectable
4fvwA-6dxpA:
undetectable
4fvwB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 PHE A 170
GLU A 174
ARG A 157
VAL A 152
None
1.42A 4fvyA-6dxpA:
undetectable
4fvyB-6dxpA:
undetectable
4fvyA-6dxpA:
undetectable
4fvyB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 ARG A 157
VAL A 152
PHE A 170
GLU A 174
None
1.43A 4fvzA-6dxpA:
undetectable
4fvzB-6dxpA:
undetectable
4fvzA-6dxpA:
undetectable
4fvzB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 PHE A 170
GLU A 174
ARG A 157
VAL A 152
None
1.40A 4fvzA-6dxpA:
undetectable
4fvzB-6dxpA:
undetectable
4fvzA-6dxpA:
undetectable
4fvzB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FW0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 PHE A 170
GLU A 174
ARG A 157
VAL A 152
None
1.41A 4fw0A-6dxpA:
undetectable
4fw0B-6dxpA:
undetectable
4fw0A-6dxpA:
undetectable
4fw0B-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSF_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 ARG A 157
VAL A 152
PHE A 170
GLU A 174
None
1.40A 4jsfA-6dxpA:
undetectable
4jsfB-6dxpA:
undetectable
4jsfA-6dxpA:
undetectable
4jsfB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 PHE A 170
GLU A 174
ARG A 157
VAL A 152
None
1.41A 4jsjA-6dxpA:
undetectable
4jsjB-6dxpA:
undetectable
4jsjA-6dxpA:
undetectable
4jsjB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5D_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 ARG A 157
VAL A 152
PHE A 170
GLU A 174
None
1.44A 4k5dA-6dxpA:
undetectable
4k5dB-6dxpA:
undetectable
4k5dA-6dxpA:
undetectable
4k5dB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5E_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 6 PHE A 170
GLU A 174
ARG A 157
VAL A 152
None
1.43A 4k5eA-6dxpA:
undetectable
4k5eB-6dxpA:
undetectable
4k5eA-6dxpA:
undetectable
4k5eB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 ARG A 157
VAL A 152
PHE A 170
GLU A 174
None
1.42A 4luxA-6dxpA:
undetectable
4luxB-6dxpA:
undetectable
4luxA-6dxpA:
undetectable
4luxB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCH_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 ARG A 157
VAL A 152
PHE A 170
GLU A 174
None
1.42A 4uchA-6dxpA:
undetectable
4uchB-6dxpA:
undetectable
4uchA-6dxpA:
undetectable
4uchB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCH_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 8 PHE A 170
GLU A 174
ARG A 157
VAL A 152
None
1.37A 4uchA-6dxpA:
undetectable
4uchB-6dxpA:
undetectable
4uchA-6dxpA:
undetectable
4uchB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH5_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)
6dxp -
(-)
4 / 7 ARG A 157
VAL A 152
PHE A 170
GLU A 174
None
1.44A 4uh5A-6dxpA:
undetectable
4uh5B-6dxpA:
undetectable
4uh5A-6dxpA:
undetectable
4uh5B-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_D_H4BD760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 PHE A 170
GLU A 174
ARG A 157
VAL A 152
None
1.38A 4v3uC-6dxpA:
undetectable
4v3uD-6dxpA:
undetectable
4v3uC-6dxpA:
undetectable
4v3uD-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3W_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 PHE A 170
GLU A 174
ARG A 157
VAL A 152
None
1.31A 4v3wA-6dxpA:
undetectable
4v3wB-6dxpA:
undetectable
4v3wA-6dxpA:
undetectable
4v3wB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3X_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 PHE A 170
GLU A 174
ARG A 157
VAL A 152
None
1.41A 4v3xA-6dxpA:
undetectable
4v3xB-6dxpA:
undetectable
4v3xA-6dxpA:
undetectable
4v3xB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 ARG A 157
VAL A 152
PHE A 170
GLU A 174
None
1.40A 4v3yA-6dxpA:
undetectable
4v3yB-6dxpA:
undetectable
4v3yA-6dxpA:
undetectable
4v3yB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z3O_F_MFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT
B,PARE30-PARC55
FUSED TOPO IV FROM
S. PNEUMONIAE
E-SITE DNA)
6dxp -
(-)
4 / 5 ARG A 183
ARG A 140
GLY A 141
GLU A 147
None
None
FMN  A 301 (-3.8A)
FMN  A 301 (-4.3A)
1.24A 4z3oA-6dxpA:
undetectable
4z3oB-6dxpA:
undetectable
4z3oA-6dxpA:
undetectable
4z3oB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 PHE A 170
GLU A 174
ARG A 157
VAL A 152
None
1.39A 5agmA-6dxpA:
undetectable
5agmB-6dxpA:
undetectable
5agmA-6dxpA:
undetectable
5agmB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 6 ARG A 157
VAL A 152
PHE A 170
GLU A 174
None
1.45A 5agnA-6dxpA:
undetectable
5agnB-6dxpA:
undetectable
5agnA-6dxpA:
undetectable
5agnB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 PHE A 170
GLU A 174
ARG A 157
VAL A 152
None
1.40A 5agnA-6dxpA:
undetectable
5agnB-6dxpA:
undetectable
5agnA-6dxpA:
undetectable
5agnB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 PHE A 170
GLU A 174
ARG A 157
VAL A 152
None
1.37A 5fvuA-6dxpA:
undetectable
5fvuB-6dxpA:
undetectable
5fvuA-6dxpA:
undetectable
5fvuB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 ARG A 157
VAL A 152
PHE A 170
GLU A 174
None
1.46A 5fvvA-6dxpA:
undetectable
5fvvB-6dxpA:
undetectable
5fvvA-6dxpA:
undetectable
5fvvB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 PHE A 170
GLU A 174
ARG A 157
VAL A 152
None
1.39A 5fvvA-6dxpA:
undetectable
5fvvB-6dxpA:
undetectable
5fvvA-6dxpA:
undetectable
5fvvB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 ARG A 157
VAL A 152
PHE A 170
GLU A 174
None
1.38A 5fvwA-6dxpA:
undetectable
5fvwB-6dxpA:
undetectable
5fvwA-6dxpA:
undetectable
5fvwB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 6 ARG A 157
VAL A 152
PHE A 170
GLU A 174
None
1.46A 5unvA-6dxpA:
undetectable
5unvB-6dxpA:
undetectable
5unvA-6dxpA:
undetectable
5unvB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 ARG A 157
VAL A 152
PHE A 170
GLU A 174
None
1.43A 5vujA-6dxpA:
undetectable
5vujB-6dxpA:
undetectable
5vujA-6dxpA:
undetectable
5vujB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_A_RBFA502_2
(RIBOFLAVIN LYASE)
6dxp -
(-)
4 / 5 GLN A  78
ASP A  77
SER A  76
ARG A 113
None
1.43A 5w4zA-6dxpA:
undetectable
5w4zA-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
6dxp -
(-)
4 / 7 PHE A 170
GLU A 174
ARG A 157
VAL A 152
None
1.42A 6auzA-6dxpA:
undetectable
6auzB-6dxpA:
undetectable
6auzA-6dxpA:
undetectable
6auzB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_B_HISB402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)
6dxp -
(-)
5 / 9 LEU A  89
GLY A 161
LEU A 160
THR A 117
VAL A 129
None
1.21A 6czmA-6dxpA:
undetectable
6czmB-6dxpA:
undetectable
6czmA-6dxpA:
undetectable
6czmB-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_E_HISE402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)
6dxp -
(-)
5 / 9 LEU A  89
GLY A 161
LEU A 160
THR A 117
VAL A 129
None
1.22A 6czmD-6dxpA:
undetectable
6czmE-6dxpA:
undetectable
6czmD-6dxpA:
undetectable
6czmE-6dxpA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_F_HISF402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)
6dxp -
(-)
5 / 10 LEU A  89
GLY A 161
LEU A 160
THR A 117
VAL A 129
None
1.23A 6czmE-6dxpA:
undetectable
6czmF-6dxpA:
undetectable
6czmE-6dxpA:
undetectable
6czmF-6dxpA:
undetectable