SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6e29'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHF_B_FOLB187_0
(DIHYDROFOLATE
REDUCTASE)		 6e29 -
(-) 		5 / 12 ILE D 198
PHE D 241
THR D 191
ILE D 217
LEU D 220
 None
 1.14A 1dhfB-6e29D:
undetectable		 1dhfB-6e29D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3003_1
(SERUM ALBUMIN)		 6e29 -
(-) 		4 / 6 HIS D 121
ILE D 137
ALA D 113
VAL D 104
 None
 0.89A 1hk1A-6e29D:
undetectable		 1hk1A-6e29D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3003_1
(SERUM ALBUMIN)		 6e29 -
(-) 		4 / 6 HIS D 121
ILE D 137
ALA D 125
VAL D 104
 None
 1.01A 1hk1A-6e29D:
undetectable		 1hk1A-6e29D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6001_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 6e29 -
(-) 		3 / 3 SER D  24
GLY D  25
ARG D  63
 None
 0.60A 1t9wA-6e29D:
undetectable		 1t9wA-6e29D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_A_P1BA1478_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 6e29 -
(-) 		4 / 7 ILE D 242
ARG D 239
ALA D 213
ILE D 217
 None
 0.80A 2xkwA-6e29D:
undetectable		 2xkwA-6e29D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E22_B_LOCB700_2
(TUBULIN BETA-2B
CHAIN)		 6e29 -
(-) 		5 / 11 LEU D  92
LEU D  95
ASN D  33
ALA D  40
VAL D  48
 None
 1.08A 3e22B-6e29D:
undetectable		 3e22B-6e29D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E22_D_LOCD700_2
(TUBULIN BETA-2B
CHAIN)		 6e29 -
(-) 		5 / 11 LEU D  92
LEU D  95
ASN D  33
ALA D  40
VAL D  48
 None
 1.09A 3e22D-6e29D:
undetectable		 3e22D-6e29D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_A_RITA600_1
(CYTOCHROME P450 3A4)		 6e29 -
(-) 		5 / 12 LEU D 229
PHE D 241
ILE D 217
ALA D 189
ILE D 206
 None
 1.08A 3nxuA-6e29D:
undetectable		 3nxuA-6e29D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_B_RITB600_1
(CYTOCHROME P450 3A4)		 6e29 -
(-) 		5 / 12 LEU D 229
PHE D 241
ILE D 217
ALA D 189
ILE D 206
 None
 1.12A 3nxuB-6e29D:
undetectable		 3nxuB-6e29D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WZD_A_LEVA1201_2
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 6e29 -
(-) 		4 / 5 LYS D 211
ILE D 216
VAL D 231
ASP D 235
 None
 1.09A 3wzdA-6e29D:
undetectable		 3wzdA-6e29D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_G_TMQG202_1
(DIHYDROFOLATE
REDUCTASE)		 6e29 -
(-) 		5 / 12 ILE D 237
ALA D 213
ILE D 217
GLN D 234
ILE D 238
 None
 1.04A 4m2xG-6e29D:
undetectable		 4m2xG-6e29D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_D_LOCD502_2
(TUBULIN BETA CHAIN)		 6e29 -
(-) 		5 / 12 LEU D  92
LEU D  95
ASN D  33
ALA D  40
VAL D  48
 None
 1.14A 4x1kD-6e29D:
undetectable		 4x1kD-6e29D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_D_LOCD502_2
(TUBULIN BETA CHAIN)		 6e29 -
(-) 		5 / 11 LEU D  92
LEU D  95
ASN D  33
ALA D  40
VAL D  48
 None
 1.09A 4x20D-6e29D:
undetectable		 4x20D-6e29D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MQT_C_STIC302_1
(DEOXYCYTIDINE KINASE)		 6e29 -
(-) 		5 / 12 GLU D 320
GLU D 261
ARG D  31
LEU D 230
GLU D 224
 None
 1.21A 5mqtC-6e29D:
undetectable		 5mqtC-6e29D:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EF6_A_BEZA401_0
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 6e29 -
(-) 		5 / 9 LEU D 196
SER D 209
ILE D 217
ARG D 195
ILE D 212
 None
 1.25A 6ef6A-6e29D:
undetectable		 6ef6A-6e29D:
undetectable