SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6e2q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_A_SAMA801_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 6e2q -
(-) 		5 / 12 ILE A 289
THR A 267
GLY A 294
GLY A 292
LEU A 316
 None
 0.92A 1rjdA-6e2qA:
undetectable		 1rjdA-6e2qA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_B_SAMB802_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 6e2q -
(-) 		5 / 12 ILE A 289
THR A 267
GLY A 294
GLY A 292
LEU A 316
 None
 0.92A 1rjdB-6e2qA:
undetectable		 1rjdB-6e2qA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 6e2q -
(-) 		5 / 12 ILE A 289
THR A 267
GLY A 294
GLY A 292
LEU A 316
 None
 0.90A 1rjdC-6e2qA:
undetectable		 1rjdC-6e2qA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP3_B_AICB2001_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 6e2q -
(-) 		5 / 10 GLU A 311
ASN A 293
THR A 291
GLU A 259
SER A 263
 None
 1.47A 3kp3A-6e2qA:
0.2
3kp3B-6e2qA:
0.4		 3kp3A-6e2qA:
undetectable
3kp3B-6e2qA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD393_1
(TETX2 PROTEIN)		 6e2q -
(-) 		4 / 5 ILE A 104
ILE A  67
TYR A  62
GLU A  66
 None
 1.22A 4a99D-6e2qA:
undetectable		 4a99D-6e2qA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB307_1
(CHITOSANASE)		 6e2q -
(-) 		4 / 7 GLU M 294
THR M 298
GLY M 295
THR M 299
 None
 0.92A 4qwpB-6e2qM:
undetectable		 4qwpB-6e2qM:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z69_A_DIFA1008_1
(SERUM ALBUMIN)		 6e2q -
(-) 		5 / 9 ALA A  86
PHE A  85
VAL A  41
LEU A 113
VAL A 112
 None
 1.33A 4z69A-6e2qA:
undetectable		 4z69A-6e2qA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_B_SAMB301_0
(UNCHARACTERIZED
PROTEIN MJ0489)		 6e2q -
(-) 		6 / 12 GLY A 295
ILE A 289
LEU A 314
THR A 291
GLY A 371
PHE A 365
 None
 1.27A 5d4uB-6e2qA:
undetectable		 5d4uB-6e2qA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUJ_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 6e2q -
(-) 		4 / 8 ALA A 286
VAL A 272
LEU A 356
ILE A 290
 None
 0.77A 5nujA-6e2qA:
undetectable		 5nujA-6e2qA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_A_ADNA506_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 6e2q -
(-) 		4 / 6 TYR A 266
LEU A 309
GLU A 311
LEU A 314
 None
 1.17A 5xooA-6e2qA:
undetectable		 5xooA-6e2qA:
undetectable