SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6e9p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_B_BEZB12_0
(CES1 PROTEIN)		 6e9p -
(-) 		4 / 4 GLY A 129
SER A  97
VAL A  58
LEU A 124
 None
 1.13A 1yajB-6e9pA:
undetectable		 1yajB-6e9pA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QL8_B_BEZB143_0
(PUTATIVE REDOX
PROTEIN)		 6e9p -
(-) 		4 / 6 ARG A  81
THR A  76
ALA A  79
PRO A  65
 None
EDO  A 503 (-3.2A)
None
EDO  A 503 (-4.5A)
 1.38A 2ql8A-6e9pA:
undetectable
2ql8B-6e9pA:
undetectable		 2ql8A-6e9pA:
undetectable
2ql8B-6e9pA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_B_CELB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 6e9p -
(-) 		5 / 12 LEU A 130
LEU A 124
ILE A  55
GLY A 101
SER A  97
 None
 1.24A 3kk6B-6e9pA:
undetectable		 3kk6B-6e9pA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RGL_A_GLYA301_0
(GLYCYL-TRNA
SYNTHETASE ALPHA
SUBUNIT)		 6e9p -
(-) 		4 / 8 ALA A 261
GLY A 258
THR A 257
ARG A 265
 None
 0.96A 3rglA-6e9pA:
undetectable		 3rglA-6e9pA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A201_1
(POL POLYPROTEIN)		 6e9p -
(-) 		5 / 9 LEU A 218
ALA A 233
ASP A 234
GLY A 204
VAL A 216
 None
 0.93A 3u7sA-6e9pA:
undetectable		 3u7sA-6e9pA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRI_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 6e9p -
(-) 		4 / 5 LEU A  12
GLY A 131
ILE A  96
VAL A  93
 None
 0.90A 3wriA-6e9pA:
undetectable		 3wriA-6e9pA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRI_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 6e9p -
(-) 		4 / 5 LEU A  12
GLY A 131
ILE A  96
VAL A  93
 None
 0.91A 3wriB-6e9pA:
undetectable		 3wriB-6e9pA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XV2_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 6e9p -
(-) 		4 / 4 GLY A 100
VAL A  49
PHE A  16
ILE A  55
 None
 1.13A 4xv2B-6e9pA:
undetectable		 4xv2B-6e9pA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_B_MZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 6e9p -
(-) 		5 / 10 ASP A 118
VAL A 117
VAL A 112
LEU A 132
THR A 134
 None
 1.25A 4yhaB-6e9pA:
undetectable		 4yhaB-6e9pA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_C_MZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 6e9p -
(-) 		5 / 11 ASP A 118
VAL A 117
VAL A 112
LEU A 132
THR A 134
 None
 1.22A 4yhaC-6e9pA:
undetectable		 4yhaC-6e9pA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NCS_A_ACTA303_0
(N-ACETYLNEURAMINIC
ACID (SIALIC ACID)
SYNTHETASE)		 6e9p -
(-) 		3 / 3 ILE A  72
THR A  71
PRO A  32
 None
ACT  A 502 (-3.8A)
None
 0.64A 6ncsA-6e9pA:
16.5		 6ncsA-6e9pA:
undetectable