SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6egx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UOB_A_PNNA1311_0
(DEACETOXYCEPHALOSPOR
IN C SYNTHETASE)		 6egx STRUCTURAL PROTEIN
VP1
(Sacbrood
virus) 		5 / 12 LEU A 130
LEU A  42
VAL A  47
PHE A  56
ILE A  58
 None
 1.49A 1uobA-6egxA:
undetectable		 1uobA-6egxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_PCFA1179_0
(WNT INHIBITORY
FACTOR 1)		 6egx STRUCTURAL PROTEIN
VP2
(Sacbrood
virus) 		5 / 12 ILE B  64
ILE B 169
MET B 114
PHE B 116
VAL B 128
 None
 1.13A 2ygnA-6egxB:
undetectable		 2ygnA-6egxB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_A_SVRA508_1
(PHOSPHOLIPASE A2)		 6egx STRUCTURAL PROTEIN
VP1
STRUCTURAL PROTEIN
VP2
(Sacbrood
virus) 		4 / 5 VAL A 176
GLN B 138
PHE B 134
ARG A 184
 None
 1.38A 3bjwE-6egxA:
undetectable		 3bjwE-6egxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC505_2
(PHOSPHOLIPASE A2)		 6egx STRUCTURAL PROTEIN
VP1
STRUCTURAL PROTEIN
VP2
(Sacbrood
virus) 		4 / 5 VAL A 176
GLN B 138
PHE B 134
ARG A 184
 None
 1.34A 3bjwH-6egxA:
undetectable		 3bjwH-6egxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_2
(PHOSPHOLIPASE A2)		 6egx STRUCTURAL PROTEIN
VP1
STRUCTURAL PROTEIN
VP2
(Sacbrood
virus) 		4 / 5 VAL A 176
GLN B 138
PHE B 134
ARG A 184
 None
 1.40A 3bjwB-6egxA:
undetectable		 3bjwB-6egxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_A_ACTA604_0
(GBAA_1210 PROTEIN)		 6egx STRUCTURAL PROTEIN
VP1
STRUCTURAL PROTEIN
VP2
(Sacbrood
virus;
Sacbrood
virus) 		4 / 6 GLY A 192
VAL A 176
HIS B 174
THR A 194
 None
 0.97A 3tj7A-6egxA:
undetectable
3tj7B-6egxA:
undetectable		 3tj7A-6egxA:
undetectable
3tj7B-6egxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC606_0
(GBAA_1210 PROTEIN)		 6egx STRUCTURAL PROTEIN
VP1
STRUCTURAL PROTEIN
VP2
(Sacbrood
virus;
Sacbrood
virus) 		4 / 6 GLY A 192
VAL A 176
HIS B 174
THR A 194
 None
 0.99A 3tj7C-6egxA:
undetectable
3tj7D-6egxA:
undetectable		 3tj7C-6egxA:
undetectable
3tj7D-6egxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_D_ACTD605_0
(GBAA_1210 PROTEIN)		 6egx STRUCTURAL PROTEIN
VP1
STRUCTURAL PROTEIN
VP2
(Sacbrood
virus;
Sacbrood
virus) 		4 / 6 VAL A 176
HIS B 174
THR A 194
GLY A 192
 None
 1.02A 3tj7C-6egxA:
undetectable
3tj7D-6egxA:
undetectable		 3tj7C-6egxA:
undetectable
3tj7D-6egxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA306_1
(CHITOSANASE)		 6egx STRUCTURAL PROTEIN
VP2
(Sacbrood
virus) 		3 / 3 SER B 136
ASP B 140
GLN B  81
 None
 0.96A 4oltA-6egxB:
undetectable
4oltB-6egxB:
undetectable		 4oltA-6egxB:
undetectable
4oltB-6egxB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD4_C_AOQC4003_1
(CYTOCHROME B)		 6egx STRUCTURAL PROTEIN
VP1
(Sacbrood
virus) 		5 / 12 ILE A  58
ILE A 144
LEU A  49
MET A 209
ILE A 106
 None
 1.06A 4pd4C-6egxA:
undetectable		 4pd4C-6egxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V20_A_ACTA1444_0
(CELLOBIOHYDROLASE)		 6egx STRUCTURAL PROTEIN
VP1
(Sacbrood
virus) 		4 / 5 GLY A 192
THR A 194
HIS A 122
GLY A 197
 None
 1.08A 4v20A-6egxA:
undetectable		 4v20A-6egxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_B_SORB1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 6egx STRUCTURAL PROTEIN
VP1
STRUCTURAL PROTEIN
VP2
(Sacbrood
virus;
Sacbrood
virus) 		4 / 7 ARG A 184
PHE A 178
ARG A  95
ILE B 142
 None
 1.38A 5a06B-6egxA:
undetectable		 5a06B-6egxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA-1B
CHAIN)		 6egx STRUCTURAL PROTEIN
VP2
(Sacbrood
virus) 		4 / 6 TYR B 110
PRO B  85
TYR B 222
LEU B 112
 None
 1.17A 5bmvB-6egxB:
undetectable		 5bmvB-6egxB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1N_G_DVAG9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 6egx STRUCTURAL PROTEIN
VP1
(Sacbrood
virus) 		3 / 3 ALA A  89
ASN A  92
LEU A  93
 None
 0.19A 5i1nB-6egxA:
undetectable		 5i1nB-6egxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1O_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 6egx STRUCTURAL PROTEIN
VP1
(Sacbrood
virus) 		3 / 3 ALA A  89
ASN A  92
LEU A  93
 None
 0.42A 5i1oC-6egxA:
undetectable		 5i1oC-6egxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1P_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 6egx STRUCTURAL PROTEIN
VP1
(Sacbrood
virus) 		3 / 3 ALA A  89
ASN A  92
LEU A  93
 None
 0.37A 5i1pA-6egxA:
undetectable		 5i1pA-6egxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VNC_C_GCSC801_1
(GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2)		 6egx STRUCTURAL PROTEIN
VP1
(Sacbrood
virus) 		5 / 10 GLY A 192
VAL A 127
ASN A 125
PRO A  59
GLY A 197
 None
 1.37A 5vncC-6egxA:
undetectable		 5vncC-6egxA:
undetectable