SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6eh1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_A_CFXA1300_2
(BETA-LACTAMASE)		 6eh1 STRUCTURAL PROTEIN
VP2
(Sacbrood
virus) 		4 / 5 TYR B  83
PRO B  85
LEU B 112
ARG B 152
 None
 1.23A 1i2wA-6eh1B:
undetectable		 1i2wA-6eh1B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_H_BEZH515_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 6eh1 STRUCTURAL PROTEIN
VP3
(Sacbrood
virus) 		4 / 6 ARG C 179
TYR C 174
ILE C 116
PRO C  86
 None
 1.22A 1oniH-6eh1C:
undetectable
1oniI-6eh1C:
undetectable		 1oniH-6eh1C:
undetectable
1oniI-6eh1C:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_J_FUAJ711_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6eh1 STRUCTURAL PROTEIN
VP3
(Sacbrood
virus) 		5 / 11 PHE C  90
LEU C 118
VAL C 236
PHE C  80
VAL C 214
 None
 1.09A 1q23J-6eh1C:
undetectable		 1q23J-6eh1C:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H9T_H_SVRH301_1
(THROMBIN)		 6eh1 STRUCTURAL PROTEIN
VP2
STRUCTURAL PROTEIN
VP3
(Sacbrood
virus) 		5 / 11 PRO B 153
ARG B 172
GLN B 147
GLY C  97
GLU C  96
 None
 1.47A 2h9tH-6eh1B:
undetectable		 2h9tH-6eh1B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RK8_A_PPFA3969_1
(PHOSPHOENOLPYRUVATE
CARBOXYKINASE,
CYTOSOLIC [GTP])		 6eh1 STRUCTURAL PROTEIN
VP3
(Sacbrood
virus) 		4 / 8 ARG C 180
ASP C 175
ARG C 179
ALA C 208
 None
 1.30A 2rk8A-6eh1C:
undetectable		 2rk8A-6eh1C:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 6eh1 STRUCTURAL PROTEIN
VP2
STRUCTURAL PROTEIN
VP3
(Sacbrood
virus;
Sacbrood
virus) 		4 / 8 THR C  66
ARG C  89
LEU B 203
ASP B  77
 None
 1.06A 2zw9A-6eh1C:
undetectable		 2zw9A-6eh1C:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJW_A_ACTA603_0
(CHOLINE OXIDASE)		 6eh1 STRUCTURAL PROTEIN
VP3
(Sacbrood
virus) 		3 / 3 ARG C 217
HIS C 151
SER C 135
 None
 0.88A 4mjwA-6eh1C:
undetectable
4mjwB-6eh1C:
undetectable		 4mjwA-6eh1C:
undetectable
4mjwB-6eh1C:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJW_B_ACTB603_0
(CHOLINE OXIDASE)		 6eh1 STRUCTURAL PROTEIN
VP3
(Sacbrood
virus) 		3 / 3 SER C 135
ARG C 217
HIS C 151
 None
 0.84A 4mjwA-6eh1C:
undetectable
4mjwB-6eh1C:
undetectable		 4mjwA-6eh1C:
undetectable
4mjwB-6eh1C:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA-1B
CHAIN)		 6eh1 STRUCTURAL PROTEIN
VP2
(Sacbrood
virus) 		4 / 6 TYR B 110
PRO B  85
TYR B 222
LEU B 112
 None
 1.03A 5bmvB-6eh1B:
undetectable		 5bmvB-6eh1B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NY7_A_NCAA303_0
(AMIDASE)		 6eh1 STRUCTURAL PROTEIN
VP3
(Sacbrood
virus) 		4 / 6 GLY C  87
PRO C  86
THR C 182
SER C 210
 None
 1.00A 5ny7A-6eh1C:
undetectable		 5ny7A-6eh1C:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6K_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 6eh1 STRUCTURAL PROTEIN
VP2
STRUCTURAL PROTEIN
VP3
(Sacbrood
virus;
Sacbrood
virus) 		3 / 3 MET B 156
ASP C 121
ARG C 239
 None
 1.11A 5z6kA-6eh1B:
undetectable		 5z6kA-6eh1B:
undetectable