SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6ehg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXT_A_MTXA2000_1
(ANTI-METHOTREXATE
CDR1-3 GRAFT VHH)		 6ehg HC3NB1
(Lama
glama) 		5 / 12 ALA C  24
MET C  34
ARG C  72
VAL C  79
ALA C  98
 None
 0.65A 3qxtA-6ehgC:
22.2		 3qxtA-6ehgC:
74.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXT_A_MTXA2000_1
(ANTI-METHOTREXATE
CDR1-3 GRAFT VHH)		 6ehg HC3NB1
(Lama
glama) 		5 / 12 VAL C   2
ALA C  24
MET C  34
ARG C  72
VAL C  79
 None
 0.89A 3qxtA-6ehgC:
22.2		 3qxtA-6ehgC:
74.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXT_B_MTXB2000_1
(ANTI-METHOTREXATE
CDR1-3 GRAFT VHH)		 6ehg HC3NB1
(Lama
glama) 		6 / 12 LEU C   4
ALA C  24
MET C  34
ARG C  72
VAL C  79
ALA C  98
 None
 0.59A 3qxtB-6ehgC:
22.5		 3qxtB-6ehgC:
74.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXT_B_MTXB2000_1
(ANTI-METHOTREXATE
CDR1-3 GRAFT VHH)		 6ehg HC3NB1
(Lama
glama) 		6 / 12 LEU C   4
MET C  34
ARG C  72
VAL C  79
ALA C  98
TYR C 112
 None
 0.61A 3qxtB-6ehgC:
22.5		 3qxtB-6ehgC:
74.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXT_B_MTXB2000_1
(ANTI-METHOTREXATE
CDR1-3 GRAFT VHH)		 6ehg HC3NB1
(Lama
glama) 		6 / 12 VAL C   2
LEU C   4
ALA C  24
MET C  34
ARG C  72
VAL C  79
 None
 0.81A 3qxtB-6ehgC:
22.5		 3qxtB-6ehgC:
74.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXT_B_MTXB2000_1
(ANTI-METHOTREXATE
CDR1-3 GRAFT VHH)		 6ehg HC3NB1
(Lama
glama) 		6 / 12 VAL C   2
LEU C   4
MET C  34
ARG C  72
VAL C  79
TYR C 112
 None
 0.86A 3qxtB-6ehgC:
22.5		 3qxtB-6ehgC:
74.07
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_A_MTXA2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 6ehg HC3NB1
(Lama
glama) 		7 / 12 ALA C  24
MET C  34
ARG C  72
ASN C  74
VAL C  79
ALA C  98
TYR C 112
 None
 0.71A 3qxvA-6ehgC:
22.2		 3qxvA-6ehgC:
57.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_B_MTXB2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 6ehg HC3NB1
(Lama
glama) 		5 / 12 ALA C  24
MET C  34
ARG C  72
VAL C  79
ALA C  98
 None
 0.74A 3qxvB-6ehgC:
22.3		 3qxvB-6ehgC:
57.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_B_MTXB2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 6ehg HC3NB1
(Lama
glama) 		5 / 12 MET C  34
ARG C  72
VAL C  79
ALA C  98
TYR C 112
 None
 0.50A 3qxvB-6ehgC:
22.3		 3qxvB-6ehgC:
57.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_C_MTXC2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 6ehg HC3NB1
(Lama
glama) 		6 / 11 ALA C  24
MET C  34
ARG C  72
ASN C  74
VAL C  79
ALA C  98
 None
 0.70A 3qxvC-6ehgC:
22.4		 3qxvC-6ehgC:
57.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_D_MTXD2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 6ehg HC3NB1
(Lama
glama) 		5 / 12 ALA C  24
MET C  34
ARG C  72
VAL C  79
ALA C  98
 None
 0.71A 3qxvD-6ehgC:
22.4		 3qxvD-6ehgC:
57.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_D_MTXD2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 6ehg HC3NB1
(Lama
glama) 		5 / 12 MET C  34
ARG C  72
VAL C  79
ALA C  98
TYR C 112
 None
 0.61A 3qxvD-6ehgC:
22.4		 3qxvD-6ehgC:
57.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_D_MTXD2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 6ehg HC3NB1
(Lama
glama) 		5 / 12 VAL C   2
ALA C  24
MET C  34
ARG C  72
VAL C  79
 None
 0.91A 3qxvD-6ehgC:
22.4		 3qxvD-6ehgC:
57.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_D_MTXD2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 6ehg HC3NB1
(Lama
glama) 		5 / 12 VAL C   2
MET C  34
ARG C  72
VAL C  79
TYR C 112
 None
 0.92A 3qxvD-6ehgC:
22.4		 3qxvD-6ehgC:
57.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_E_MTXE2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 6ehg HC3NB1
(Lama
glama) 		5 / 12 MET C  34
ARG C  72
VAL C  79
ALA C  98
TYR C 112
 None
 0.59A 3qxvE-6ehgC:
18.8		 3qxvE-6ehgC:
57.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA505_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 6ehg HC3NB1
(Lama
glama) 		3 / 3 THR C 100
ASN C 111
GLU C 109
 None
 0.70A 3v4tA-6ehgC:
undetectable
3v4tC-6ehgC:
undetectable		 3v4tA-6ehgC:
undetectable
3v4tC-6ehgC:
undetectable