SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6ehi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_D_SAMD200_0
(METHIONINE REPRESSOR)		 6ehi NUCLEASE NUCT
(Helicobacter
pylori) 		5 / 12 ALA A 116
GLY A 114
ALA A 122
LEU A   6
PRO A   7
 ACT  A 201 (-3.6A)
ACT  A 201 (-3.3A)
GOL  A 202 ( 3.8A)
None
None
 1.10A 1mjqC-6ehiA:
undetectable
1mjqD-6ehiA:
undetectable		 1mjqC-6ehiA:
undetectable
1mjqD-6ehiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_J_SAMJ200_0
(METHIONINE REPRESSOR)		 6ehi NUCLEASE NUCT
(Helicobacter
pylori) 		5 / 12 ALA A 116
GLY A 114
ALA A 122
LEU A   6
PRO A   7
 ACT  A 201 (-3.6A)
ACT  A 201 (-3.3A)
GOL  A 202 ( 3.8A)
None
None
 1.11A 1mjqI-6ehiA:
undetectable
1mjqJ-6ehiA:
undetectable		 1mjqI-6ehiA:
undetectable
1mjqJ-6ehiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q97_B_ADNB486_1
(SR PROTEIN KINASE)		 6ehi NUCLEASE NUCT
(Helicobacter
pylori) 		4 / 4 VAL A  28
ALA A 104
LEU A  17
PHE A 112
 None
 1.12A 1q97B-6ehiA:
undetectable		 1q97B-6ehiA:
12.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKF_A_AB1A501_1
(PROTEASE RETROPEPSIN)		 6ehi NUCLEASE NUCT
(Helicobacter
pylori) 		5 / 12 ALA A  24
ILE A 110
ILE A  18
ALA A 104
ILE A 106
 None
 0.92A 2rkfA-6ehiA:
undetectable		 2rkfA-6ehiA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_A_TOPA1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 6ehi NUCLEASE NUCT
(Helicobacter
pylori) 		5 / 11 ILE A  56
ALA A 104
LEU A  17
ILE A  44
PHE A  35
 None
 0.87A 2w9sA-6ehiA:
undetectable		 2w9sA-6ehiA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_B_TOPB1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 6ehi NUCLEASE NUCT
(Helicobacter
pylori) 		5 / 11 ILE A  56
ALA A 104
LEU A  17
ILE A  44
PHE A  35
 None
 0.87A 2w9sB-6ehiA:
undetectable		 2w9sB-6ehiA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_C_TOPC1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 6ehi NUCLEASE NUCT
(Helicobacter
pylori) 		5 / 10 ILE A  56
ALA A 104
LEU A  17
ILE A  44
PHE A  35
 None
 0.86A 2w9sC-6ehiA:
undetectable		 2w9sC-6ehiA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_D_TOPD1158_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 6ehi NUCLEASE NUCT
(Helicobacter
pylori) 		5 / 10 ILE A  56
ALA A 104
LEU A  17
ILE A  44
PHE A  35
 None
 0.82A 2w9sD-6ehiA:
undetectable		 2w9sD-6ehiA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_E_TOPE1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 6ehi NUCLEASE NUCT
(Helicobacter
pylori) 		4 / 8 ALA A 104
LEU A  17
ILE A  44
PHE A  35
 None
 0.80A 2w9sE-6ehiA:
undetectable		 2w9sE-6ehiA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_E_TOPE1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 6ehi NUCLEASE NUCT
(Helicobacter
pylori) 		4 / 8 ILE A  56
LEU A  17
ILE A  44
PHE A  35
 None
 0.76A 2w9sE-6ehiA:
undetectable		 2w9sE-6ehiA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_F_TOPF1159_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 6ehi NUCLEASE NUCT
(Helicobacter
pylori) 		5 / 10 ILE A  56
ALA A 104
LEU A  17
ILE A  44
PHE A  35
 None
 0.81A 2w9sF-6ehiA:
undetectable		 2w9sF-6ehiA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A8I_B_C2FB401_0
(AMINOMETHYLTRANSFERA
SE)		 6ehi NUCLEASE NUCT
(Helicobacter
pylori) 		5 / 12 ILE A  56
TYR A  58
VAL A  82
PHE A  35
TYR A  77
 None
 1.48A 3a8iB-6ehiA:
undetectable		 3a8iB-6ehiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW3_B_TOPB208_1
(DIHYDROFOLATE
REDUCTASE)		 6ehi NUCLEASE NUCT
(Helicobacter
pylori) 		5 / 9 ALA A  48
LEU A  74
VAL A  28
ILE A  40
ILE A  21
 None
 1.28A 3jw3B-6ehiA:
undetectable		 3jw3B-6ehiA:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_A_SAMA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 6ehi NUCLEASE NUCT
(Helicobacter
pylori) 		4 / 8 ALA A 116
ASP A  39
ILE A  40
ILE A  21
 ACT  A 201 (-3.6A)
None
None
None
 0.88A 4ndnB-6ehiA:
undetectable		 4ndnB-6ehiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_C_SAMC405_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 6ehi NUCLEASE NUCT
(Helicobacter
pylori) 		4 / 8 ALA A 116
ASP A  39
ILE A  40
ILE A  21
 ACT  A 201 (-3.6A)
None
None
None
 0.91A 4ndnD-6ehiA:
undetectable		 4ndnD-6ehiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP8_C_ASCC501_0
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)		 6ehi NUCLEASE NUCT
(Helicobacter
pylori) 		5 / 12 LEU A  17
ILE A 106
ILE A  40
ALA A  43
ILE A  30
 None
 0.98A 4rp8C-6ehiA:
undetectable		 4rp8C-6ehiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YMG_A_SAMA1001_0
(PUTATIVE
SAM-DEPENDENT
O-METHYLTRANFERASE)		 6ehi NUCLEASE NUCT
(Helicobacter
pylori) 		5 / 12 TYR A  60
TYR A  96
TYR A  58
ALA A  31
TYR A 146
 None
 1.28A 4ymgA-6ehiA:
2.6		 4ymgA-6ehiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YMG_B_SAMB1001_0
(PUTATIVE
SAM-DEPENDENT
O-METHYLTRANFERASE)		 6ehi NUCLEASE NUCT
(Helicobacter
pylori) 		5 / 12 TYR A  60
TYR A  96
TYR A  58
ALA A  31
TYR A 146
 None
 1.28A 4ymgB-6ehiA:
2.8		 4ymgB-6ehiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D75_A_FK5A301_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP3)		 6ehi NUCLEASE NUCT
(Helicobacter
pylori) 		5 / 11 VAL A  82
ILE A  56
ALA A  43
ILE A  21
PHE A  35
 None
 1.18A 5d75A-6ehiA:
undetectable		 5d75A-6ehiA:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBN_B_SAMB401_0
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 6ehi NUCLEASE NUCT
(Helicobacter
pylori) 		4 / 7 ALA A 116
ASP A  39
ILE A  40
ILE A  21
 ACT  A 201 (-3.6A)
None
None
None
 0.88A 6fbnA-6ehiA:
undetectable		 6fbnA-6ehiA:
undetectable