SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6ehn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DRA_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 6ehn CARBOHYDRATE
ESTERASE MZ0003
(unidentified
prokaryotic
organism) 		5 / 12 GLU A 164
LEU A  73
ILE A 129
LEU A  98
ILE A 123
 None
 1.02A 1draA-6ehnA:
undetectable		 1draA-6ehnA:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DRA_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)		 6ehn CARBOHYDRATE
ESTERASE MZ0003
(unidentified
prokaryotic
organism) 		5 / 12 GLU A 164
LEU A  73
ILE A 129
LEU A  98
ILE A 123
 None
 1.02A 1draB-6ehnA:
undetectable		 1draB-6ehnA:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_A_DVAA6_0
(MINI-GRAMICIDIN A)		 6ehn CARBOHYDRATE
ESTERASE MZ0003
(unidentified
prokaryotic
organism) 		3 / 3 ALA A 388
VAL A 386
TRP A 161
 None
 0.87A 1tkqA-6ehnA:
undetectable		 1tkqA-6ehnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_A_STRA1001_2
(MINERALOCORTICOID
RECEPTOR)		 6ehn CARBOHYDRATE
ESTERASE MZ0003
(unidentified
prokaryotic
organism) 		4 / 4 LEU A 315
LEU A 274
SER A 275
LEU A 308
 None
 1.14A 1ya3A-6ehnA:
undetectable		 1ya3A-6ehnA:
14.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_A_NCAA506_0
(NAD-DEPENDENT
DEACETYLASE 2)		 6ehn CARBOHYDRATE
ESTERASE MZ0003
(unidentified
prokaryotic
organism) 		4 / 6 ALA A  94
PHE A  86
ILE A 176
ASP A  96
 None
 0.97A 1yc2A-6ehnA:
undetectable		 1yc2A-6ehnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO5_A_CHDA131_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 6ehn CARBOHYDRATE
ESTERASE MZ0003
(unidentified
prokaryotic
organism) 		5 / 12 ILE A 212
ILE A 316
LEU A 315
CYH A 319
THR A 262
 None
 1.20A 2qo5A-6ehnA:
1.4		 2qo5A-6ehnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA608_1
(CHITINASE A)		 6ehn CARBOHYDRATE
ESTERASE MZ0003
(unidentified
prokaryotic
organism) 		4 / 6 ASN A 265
SER A 243
HIS A 384
ASP A 385
 None
GOL  A 501 (-2.7A)
None
None
 1.15A 3aruA-6ehnA:
undetectable		 3aruA-6ehnA:
9.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BSZ_F_RTLF178_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 6ehn CARBOHYDRATE
ESTERASE MZ0003
(unidentified
prokaryotic
organism) 		5 / 11 LEU A  21
ALA A 347
ALA A 320
MET A 353
GLN A  34
 None
 1.34A 3bszF-6ehnA:
undetectable		 3bszF-6ehnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKA_A_SAMA400_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE H)		 6ehn CARBOHYDRATE
ESTERASE MZ0003
(unidentified
prokaryotic
organism) 		5 / 12 GLY A 357
ARG A 352
GLY A 355
ASP A 360
GLU A 396
 None
 1.40A 3tkaA-6ehnA:
2.3		 3tkaA-6ehnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A84_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 6ehn CARBOHYDRATE
ESTERASE MZ0003
(unidentified
prokaryotic
organism) 		5 / 12 ASP A 390
VAL A 393
ILE A 263
ILE A 316
LEU A 370
 None
 1.26A 4a84A-6ehnA:
undetectable		 4a84A-6ehnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD393_1
(TETX2 PROTEIN)		 6ehn CARBOHYDRATE
ESTERASE MZ0003
(unidentified
prokaryotic
organism) 		4 / 5 ILE A 129
GLN A  81
ILE A  99
TYR A 100
 None
 1.15A 4a99D-6ehnA:
undetectable		 4a99D-6ehnA:
12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HFP_B_15UB402_1
(PROTHROMBIN)		 6ehn CARBOHYDRATE
ESTERASE MZ0003
(unidentified
prokaryotic
organism) 		5 / 12 ALA A 273
ILE A 212
GLU A 340
GLY A 246
GLY A 241
 None
 1.19A 4hfpB-6ehnA:
undetectable		 4hfpB-6ehnA:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM5_A_SREA603_1
(TRANSPORTER)		 6ehn CARBOHYDRATE
ESTERASE MZ0003
(unidentified
prokaryotic
organism) 		5 / 9 PRO A  20
VAL A 350
ALA A 349
TYR A 351
GLY A 346
 None
 1.26A 4mm5A-6ehnA:
undetectable		 4mm5A-6ehnA:
9.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMA_A_CXXA603_1
(TRANSPORTER)		 6ehn CARBOHYDRATE
ESTERASE MZ0003
(unidentified
prokaryotic
organism) 		5 / 11 PRO A  20
VAL A 350
ALA A 349
TYR A 351
GLY A 346
 None
 1.26A 4mmaA-6ehnA:
undetectable		 4mmaA-6ehnA:
9.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_A_29EA603_1
(TRANSPORTER)		 6ehn CARBOHYDRATE
ESTERASE MZ0003
(unidentified
prokaryotic
organism) 		5 / 10 PRO A  20
VAL A 350
ALA A 349
TYR A 351
GLY A 346
 None
 1.23A 4mmdA-6ehnA:
undetectable		 4mmdA-6ehnA:
9.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_B_29EB603_1
(TRANSPORTER)		 6ehn CARBOHYDRATE
ESTERASE MZ0003
(unidentified
prokaryotic
organism) 		5 / 12 PRO A  20
VAL A 350
ALA A 349
TYR A 351
GLY A 346
 None
 1.20A 4mmdB-6ehnA:
undetectable		 4mmdB-6ehnA:
9.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UG5_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 6ehn CARBOHYDRATE
ESTERASE MZ0003
(unidentified
prokaryotic
organism) 		3 / 3 ARG A 137
THR A 211
TRP A 293
 None
 1.18A 4ug5A-6ehnA:
undetectable		 4ug5A-6ehnA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T7B_A_IPHA901_0
(PROTEIN ARGONAUTE-2)		 6ehn CARBOHYDRATE
ESTERASE MZ0003
(unidentified
prokaryotic
organism) 		4 / 6 PRO A 323
VAL A 324
ALA A 320
THR A 356
 None
 1.09A 5t7bA-6ehnA:
2.4		 5t7bA-6ehnA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYC_A_1YNA502_1
(PROTEIN CYP51)		 6ehn CARBOHYDRATE
ESTERASE MZ0003
(unidentified
prokaryotic
organism) 		5 / 12 ALA A 166
PHE A 226
ALA A 216
THR A 248
LEU A 115
 None
 1.33A 6aycA-6ehnA:
undetectable		 6aycA-6ehnA:
25.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0I_B_TA1B502_1
(TUBULIN BETA CHAIN)		 6ehn CARBOHYDRATE
ESTERASE MZ0003
(unidentified
prokaryotic
organism) 		5 / 12 ASP A 311
LEU A 359
ALA A 347
GLY A 271
LEU A 250
 None
 1.05A 6b0iB-6ehnA:
undetectable		 6b0iB-6ehnA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBD_A_TRPA903_0
(PROTEIN ARGONAUTE-2)		 6ehn CARBOHYDRATE
ESTERASE MZ0003
(unidentified
prokaryotic
organism) 		4 / 6 ILE A 163
GLN A 162
ILE A 395
ASP A 392
 None
 1.02A 6cbdA-6ehnA:
2.1		 6cbdA-6ehnA:
undetectable