SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6ei1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3001_1
(SERUM ALBUMIN)		 6ei1 ZINC FINGER WITH
UFM1-SPECIFIC
PEPTIDASE DOMAIN
PROTEIN
(Homo
sapiens) 		5 / 9 HIS A 488
LEU A 486
ARG A 493
LEU A 458
HIS A 455
 None
 1.45A 1hk2A-6ei1A:
0.4		 1hk2A-6ei1A:
8.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M8E_B_H4BB903_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 6ei1 ZINC FINGER WITH
UFM1-SPECIFIC
PEPTIDASE DOMAIN
PROTEIN
(Homo
sapiens) 		3 / 3 ARG A 338
ILE A 498
TRP A 341
 None
 0.94A 1m8eB-6ei1A:
undetectable		 1m8eB-6ei1A:
11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 6ei1 ZINC FINGER WITH
UFM1-SPECIFIC
PEPTIDASE DOMAIN
PROTEIN
(Homo
sapiens) 		3 / 3 ARG A 338
ILE A 498
TRP A 341
 None
 0.85A 1nodB-6ei1A:
undetectable		 1nodB-6ei1A:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QOM_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE)		 6ei1 ZINC FINGER WITH
UFM1-SPECIFIC
PEPTIDASE DOMAIN
PROTEIN
(Homo
sapiens) 		3 / 3 ARG A 338
ILE A 498
TRP A 341
 None
 1.01A 1qomA-6ei1A:
undetectable		 1qomA-6ei1A:
11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU2_A_MRCA1993_2
(ISOLEUCYL-TRNA
SYNTHETASE)		 6ei1 ZINC FINGER WITH
UFM1-SPECIFIC
PEPTIDASE DOMAIN
PROTEIN
(Homo
sapiens) 		3 / 3 GLU A 428
TRP A 401
LYS A 481
 None
 1.42A 1qu2A-6ei1A:
1.3		 1qu2A-6ei1A:
7.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB2_2
(CES1 PROTEIN)		 6ei1 ZINC FINGER WITH
UFM1-SPECIFIC
PEPTIDASE DOMAIN
PROTEIN
(Homo
sapiens) 		4 / 4 LEU A 508
PRO A 482
ILE A 550
LEU A 486
 None
 1.02A 1ya4B-6ei1A:
undetectable		 1ya4B-6ei1A:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC3_2
(CES1 PROTEIN)		 6ei1 ZINC FINGER WITH
UFM1-SPECIFIC
PEPTIDASE DOMAIN
PROTEIN
(Homo
sapiens) 		4 / 4 LEU A 508
PRO A 482
ILE A 550
LEU A 486
 None
 1.01A 1ya4C-6ei1A:
undetectable		 1ya4C-6ei1A:
8.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AB2_A_SNLA502_1
(MINERALOCORTICOID
RECEPTOR)		 6ei1 ZINC FINGER WITH
UFM1-SPECIFIC
PEPTIDASE DOMAIN
PROTEIN
(Homo
sapiens) 		5 / 12 LEU A 373
PHE A 365
MET A 385
MET A 396
CYH A 381
 None
 1.48A 2ab2A-6ei1A:
undetectable		 2ab2A-6ei1A:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AB2_B_SNLB503_1
(MINERALOCORTICOID
RECEPTOR)		 6ei1 ZINC FINGER WITH
UFM1-SPECIFIC
PEPTIDASE DOMAIN
PROTEIN
(Homo
sapiens) 		5 / 12 LEU A 373
PHE A 365
MET A 385
MET A 396
CYH A 381
 None
 1.46A 2ab2B-6ei1A:
undetectable		 2ab2B-6ei1A:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FK8_A_SAMA302_1
(METHOXY MYCOLIC ACID
SYNTHASE 4)		 6ei1 ZINC FINGER WITH
UFM1-SPECIFIC
PEPTIDASE DOMAIN
PROTEIN
(Homo
sapiens) 		3 / 3 SER A 351
THR A 420
GLN A 394
 None
 0.80A 2fk8A-6ei1A:
undetectable		 2fk8A-6ei1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 6ei1 ZINC FINGER WITH
UFM1-SPECIFIC
PEPTIDASE DOMAIN
PROTEIN
(Homo
sapiens) 		3 / 3 ARG A 338
ILE A 498
TRP A 341
 None
 0.86A 2nodB-6ei1A:
undetectable		 2nodB-6ei1A:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_A_SAMA300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 6ei1 ZINC FINGER WITH
UFM1-SPECIFIC
PEPTIDASE DOMAIN
PROTEIN
(Homo
sapiens) 		3 / 3 SER A 492
HIS A 350
ASP A 314
 None
 0.84A 2oxtA-6ei1A:
undetectable		 2oxtA-6ei1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_A_ACTA141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 6ei1 ZINC FINGER WITH
UFM1-SPECIFIC
PEPTIDASE DOMAIN
PROTEIN
(Homo
sapiens) 		3 / 3 VAL A 337
ASP A 336
GLU A 499
 None
 0.74A 2qeuA-6ei1A:
undetectable		 2qeuA-6ei1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E68_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 6ei1 ZINC FINGER WITH
UFM1-SPECIFIC
PEPTIDASE DOMAIN
PROTEIN
(Homo
sapiens) 		3 / 3 ARG A 338
ILE A 498
TRP A 341
 None
 0.90A 3e68A-6ei1A:
undetectable		 3e68A-6ei1A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E6T_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 6ei1 ZINC FINGER WITH
UFM1-SPECIFIC
PEPTIDASE DOMAIN
PROTEIN
(Homo
sapiens) 		3 / 3 ARG A 338
ILE A 498
TRP A 341
 None
 0.91A 3e6tB-6ei1A:
undetectable		 3e6tB-6ei1A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7I_B_H4BB2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 6ei1 ZINC FINGER WITH
UFM1-SPECIFIC
PEPTIDASE DOMAIN
PROTEIN
(Homo
sapiens) 		3 / 3 ARG A 338
ILE A 498
TRP A 341
 None
 0.88A 3e7iB-6ei1A:
undetectable		 3e7iB-6ei1A:
11.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 6ei1 ZINC FINGER WITH
UFM1-SPECIFIC
PEPTIDASE DOMAIN
PROTEIN
(Homo
sapiens) 		3 / 3 ARG A 338
ILE A 498
TRP A 341
 None
 0.97A 3nw2A-6ei1A:
undetectable		 3nw2A-6ei1A:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 6ei1 ZINC FINGER WITH
UFM1-SPECIFIC
PEPTIDASE DOMAIN
PROTEIN
(Homo
sapiens) 		3 / 3 ARG A 338
ILE A 498
TRP A 341
 None
 0.91A 3nw2B-6ei1A:
undetectable		 3nw2B-6ei1A:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PMZ_E_TUBE220_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 6ei1 ZINC FINGER WITH
UFM1-SPECIFIC
PEPTIDASE DOMAIN
PROTEIN
(Homo
sapiens) 		4 / 6 TYR A 362
GLN A 366
ILE A 390
SER A 492
 None
 1.32A 3pmzD-6ei1A:
undetectable		 3pmzD-6ei1A:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 6ei1 ZINC FINGER WITH
UFM1-SPECIFIC
PEPTIDASE DOMAIN
PROTEIN
(Homo
sapiens) 		4 / 8 ILE A 397
ILE A 424
SER A 352
GLY A 359
 None
None
None
AYE  A 601 ( 4.7A)
 0.83A 4acbC-6ei1A:
undetectable		 4acbC-6ei1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EY7_A_E20A604_1
(ACETYLCHOLINESTERASE)		 6ei1 ZINC FINGER WITH
UFM1-SPECIFIC
PEPTIDASE DOMAIN
PROTEIN
(Homo
sapiens) 		5 / 11 TRP A 423
GLY A 357
TYR A 362
HIS A 491
GLY A 490
 AYE  A 601 (-3.0A)
AYE  A 601 ( 4.0A)
None
AYE  A 601 (-4.1A)
AYE  A 601 (-3.8A)
 1.19A 4ey7A-6ei1A:
undetectable		 4ey7A-6ei1A:
7.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EY7_B_E20B605_1
(ACETYLCHOLINESTERASE)		 6ei1 ZINC FINGER WITH
UFM1-SPECIFIC
PEPTIDASE DOMAIN
PROTEIN
(Homo
sapiens) 		5 / 11 TRP A 423
GLY A 357
TYR A 362
HIS A 491
GLY A 490
 AYE  A 601 (-3.0A)
AYE  A 601 ( 4.0A)
None
AYE  A 601 (-4.1A)
AYE  A 601 (-3.8A)
 1.21A 4ey7B-6ei1A:
undetectable		 4ey7B-6ei1A:
7.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_B_SAMB301_1
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 6ei1 ZINC FINGER WITH
UFM1-SPECIFIC
PEPTIDASE DOMAIN
PROTEIN
(Homo
sapiens) 		4 / 5 TYR A 275
GLN A 279
ASP A 313
ASP A 347
 None
 1.26A 4qtuB-6ei1A:
undetectable		 4qtuB-6ei1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4S0V_A_SUVA2001_2
(HUMAN OREXIN
RECEPTOR TYPE 2
FUSION PROTEIN TO P.
ABYSII GLYCOGEN
SYNTHASE)		 6ei1 ZINC FINGER WITH
UFM1-SPECIFIC
PEPTIDASE DOMAIN
PROTEIN
(Homo
sapiens) 		4 / 5 ILE A 484
PRO A 483
TYR A 330
VAL A 340
 None
 1.21A 4s0vA-6ei1A:
undetectable		 4s0vA-6ei1A:
9.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_C_ACTC401_0
(PROTON-GATED ION
CHANNEL)		 6ei1 ZINC FINGER WITH
UFM1-SPECIFIC
PEPTIDASE DOMAIN
PROTEIN
(Homo
sapiens) 		4 / 7 ILE A 462
PHE A 459
VAL A 495
ILE A 510
 None
 0.96A 4zzbC-6ei1A:
undetectable
4zzbD-6ei1A:
undetectable		 4zzbC-6ei1A:
undetectable
4zzbD-6ei1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FUQ_A_ACTA1278_0
(NAD(P)H
DEHYDROGENASE
[QUINONE] 1)		 6ei1 ZINC FINGER WITH
UFM1-SPECIFIC
PEPTIDASE DOMAIN
PROTEIN
(Homo
sapiens) 		4 / 5 SER A 351
GLN A 366
ILE A 390
TYR A 362
 None
 0.99A 5fuqA-6ei1A:
undetectable
5fuqB-6ei1A:
undetectable		 5fuqA-6ei1A:
undetectable
5fuqB-6ei1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_H_RITH602_1
(CYTOCHROME P450 3A5)		 6ei1 ZINC FINGER WITH
UFM1-SPECIFIC
PEPTIDASE DOMAIN
PROTEIN
(Homo
sapiens) 		5 / 12 LEU A 432
GLY A 311
ILE A 424
ALA A 422
THR A 420
 None
 0.85A 5veuH-6ei1A:
undetectable		 5veuH-6ei1A:
10.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_A_RBFA502_2
(RIBOFLAVIN LYASE)		 6ei1 ZINC FINGER WITH
UFM1-SPECIFIC
PEPTIDASE DOMAIN
PROTEIN
(Homo
sapiens) 		4 / 5 GLN A 278
ASP A 355
SER A 351
ARG A 363
 None
 1.39A 5w4zA-6ei1A:
undetectable		 5w4zA-6ei1A:
17.65