SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6eid'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_R_TFPR201_1
(PROTEIN S100-A4)		 6eid ARCHAEAL-TYPE OPSIN
2
(Chlamydomonas
reinhardtii) 		5 / 10 GLY A 185
ILE A 228
PHE A 237
PHE A 178
GLY A 163
 LYR  A 257 ( 4.2A)
None
OLC  A1101 (-3.4A)
OLC  A1101 ( 4.0A)
LYR  A 257 ( 3.7A)
 0.99A 3ko0R-6eidA:
undetectable
3ko0T-6eidA:
0.6		 3ko0R-6eidA:
18.81
3ko0T-6eidA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_R_TFPR201_1
(PROTEIN S100-A4)		 6eid ARCHAEAL-TYPE OPSIN
2
(Chlamydomonas
reinhardtii) 		5 / 10 GLY A 185
PHE A 237
PHE A 178
GLY A 163
PHE A 230
 LYR  A 257 ( 4.2A)
OLC  A1101 (-3.4A)
OLC  A1101 ( 4.0A)
LYR  A 257 ( 3.7A)
LYR  A 257 ( 4.7A)
 1.48A 3ko0R-6eidA:
undetectable
3ko0T-6eidA:
0.6		 3ko0R-6eidA:
18.81
3ko0T-6eidA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_A_ACTA5_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 6eid ARCHAEAL-TYPE OPSIN
2
(Chlamydomonas
reinhardtii) 		3 / 3 LYS A  93
SER A  52
GLN A  56
 None
 1.31A 3si7A-6eidA:
undetectable		 3si7A-6eidA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1477_0
(MJ0495-LIKE PROTEIN)		 6eid ARCHAEAL-TYPE OPSIN
2
(Chlamydomonas
reinhardtii) 		4 / 6 THR A 246
GLY A 248
ILE A 252
LEU A  55
 None
OLC  A1102 ( 3.7A)
None
None
 0.73A 4ac9C-6eidA:
undetectable		 4ac9C-6eidA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1477_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 6eid ARCHAEAL-TYPE OPSIN
2
(Chlamydomonas
reinhardtii) 		4 / 6 THR A 246
GLY A 248
ILE A 252
LEU A  55
 None
OLC  A1102 ( 3.7A)
None
None
 0.78A 4acaC-6eidA:
undetectable		 4acaC-6eidA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M93_B_ACTB303_0
(S25-26 FAB (IGG1K)
HEAVY CHAIN
S25-26 FAB (IGG1K)
LIGHT CHAIN)		 6eid ARCHAEAL-TYPE OPSIN
2
(Chlamydomonas
reinhardtii) 		4 / 5 GLY A 163
SER A 166
ALA A 167
GLU A 235
 LYR  A 257 ( 3.7A)
None
None
None
 1.07A 4m93B-6eidA:
undetectable
4m93C-6eidA:
undetectable		 4m93B-6eidA:
undetectable
4m93C-6eidA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EID_A_EDTA1111_0
(ARCHAEAL-TYPE OPSIN
2)		 6eid ARCHAEAL-TYPE OPSIN
2
(Chlamydomonas
reinhardtii) 		4 / 4 GLN A  49
ASN A  53
PHE A  98
TYR A 243
 EDT  A1111 (-4.1A)
EDT  A1111 (-2.6A)
EDT  A1111 (-4.1A)
EDT  A1111 (-4.7A)
 0.00A 6eidA-6eidA:
42.8		 6eidA-6eidA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_B_ACTB403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 6eid ARCHAEAL-TYPE OPSIN
2
(Chlamydomonas
reinhardtii) 		3 / 3 PHE A 102
ARG A 115
GLN A 117
 None
 1.18A 6g1pB-6eidA:
undetectable		 6g1pB-6eidA:
23.02