SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6eih'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_U_9CRU502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 6eih 14-3-3 PROTEIN
EPSILON
(Homo
sapiens) 		5 / 12 ALA A 145
ALA A 144
ILE A  53
CYH A  97
LEU A 101
 None
 1.01A 1fm6U-6eihA:
undetectable		 1fm6U-6eihA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NNC_A_ZMRA479_1
(NEURAMINIDASE N9)		 6eih 14-3-3 PROTEIN
EPSILON
(Homo
sapiens) 		5 / 12 ARG A  61
GLU A 183
ARG A 130
ASN A 176
ARG A  57
 None
 0.93A 1nncA-6eihA:
undetectable		 1nncA-6eihA:
11.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_A_ZMRA1477_1
(NEURAMINIDASE)		 6eih 14-3-3 PROTEIN
EPSILON
(Homo
sapiens) 		5 / 12 ARG A  61
GLU A 183
ARG A 130
ASN A 176
ARG A  57
 None
 0.96A 2cmlA-6eihA:
undetectable		 2cmlA-6eihA:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_B_ZMRB2477_1
(NEURAMINIDASE)		 6eih 14-3-3 PROTEIN
EPSILON
(Homo
sapiens) 		5 / 12 ARG A  61
GLU A 183
ARG A 130
ASN A 176
ARG A  57
 None
 0.94A 2cmlB-6eihA:
undetectable		 2cmlB-6eihA:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_C_ZMRC3477_1
(NEURAMINIDASE)		 6eih 14-3-3 PROTEIN
EPSILON
(Homo
sapiens) 		5 / 12 ARG A  61
GLU A 183
ARG A 130
ASN A 176
ARG A  57
 None
 0.92A 2cmlC-6eihA:
undetectable		 2cmlC-6eihA:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_D_ZMRD4477_1
(NEURAMINIDASE)		 6eih 14-3-3 PROTEIN
EPSILON
(Homo
sapiens) 		5 / 12 ARG A  61
GLU A 183
ARG A 130
ASN A 176
ARG A  57
 None
 0.98A 2cmlD-6eihA:
undetectable		 2cmlD-6eihA:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_C_RBVC601_1
(RNA POLYMERASE)		 6eih 14-3-3 PROTEIN
EPSILON
(Homo
sapiens) 		5 / 11 ARG A  57
LEU A  93
LEU A 101
GLY A 126
ASP A 127
 None
 1.27A 3sfuC-6eihA:
undetectable		 3sfuC-6eihA:
8.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7N_A_ZMRA601_1
(NEURAMINIDASE)		 6eih 14-3-3 PROTEIN
EPSILON
(Homo
sapiens) 		5 / 12 ARG A  61
GLU A 183
ARG A 130
ASN A 176
ARG A  57
 None
 0.98A 4b7nA-6eihA:
undetectable		 4b7nA-6eihA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWV_A_BCZA513_1
(NEURAMINIDASE)		 6eih 14-3-3 PROTEIN
EPSILON
(Homo
sapiens) 		3 / 3 ARG A  61
GLU A 183
ARG A  57
 None
 0.75A 4mwvA-6eihA:
undetectable		 4mwvA-6eihA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TJZ_A_BEZA302_0
(4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE)		 6eih 14-3-3 PROTEIN
EPSILON
(Homo
sapiens) 		3 / 3 MET A  33
GLU A   5
ARG A   4
 None
 1.11A 5tjzA-6eihA:
undetectable		 5tjzA-6eihA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A60_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 6eih 14-3-3 PROTEIN
EPSILON
(Homo
sapiens) 		5 / 12 ALA A 145
ALA A 144
ILE A  53
CYH A  97
LEU A 101
 None
 1.05A 6a60D-6eihA:
undetectable		 6a60D-6eihA:
21.43