SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6eio'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB2_0
(ACTINOMYCIN D)		 6eio ANTIFREEZE PROTEIN
(uncultured
bacterium) 		3 / 3 THR A 210
PRO A 181
THR A 208
 None
 0.89A 1a7yB-6eioA:
undetectable		 1a7yB-6eioA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_D_ASDD1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 6eio ANTIFREEZE PROTEIN
(uncultured
bacterium) 		4 / 7 ILE A 134
GLY A 135
LEU A 186
PHE A 212
 None
 0.89A 2vctD-6eioA:
undetectable		 2vctD-6eioA:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_A_RBFA190_1
(RIBOFLAVIN UPTAKE
PROTEIN)		 6eio ANTIFREEZE PROTEIN
(uncultured
bacterium) 		5 / 12 GLY A 214
ALA A 193
ALA A 191
LEU A 187
LEU A 230
 None
 1.16A 3p5nA-6eioA:
undetectable		 3p5nA-6eioA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_B_RBFB190_1
(RIBOFLAVIN UPTAKE
PROTEIN)		 6eio ANTIFREEZE PROTEIN
(uncultured
bacterium) 		5 / 12 GLY A 214
ALA A 193
ALA A 191
LEU A 187
LEU A 230
 None
 1.15A 3p5nB-6eioA:
undetectable		 3p5nB-6eioA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q70_A_RITA2001_2
(CANDIDAPEPSIN-2)		 6eio ANTIFREEZE PROTEIN
(uncultured
bacterium) 		4 / 6 THR A 210
ILE A 171
ASP A 156
THR A 229
 None
 0.90A 3q70A-6eioA:
undetectable		 3q70A-6eioA:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5T_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 6eio ANTIFREEZE PROTEIN
(uncultured
bacterium) 		4 / 6 ILE A 171
GLN A 172
ILE A  50
ASP A 118
 None
 1.20A 4w5tA-6eioA:
undetectable		 4w5tA-6eioA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XV2_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 6eio ANTIFREEZE PROTEIN
(uncultured
bacterium) 		4 / 4 GLY A  79
VAL A  66
PHE A 206
ILE A 222
 None
 0.90A 4xv2B-6eioA:
undetectable		 4xv2B-6eioA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESM_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 6eio ANTIFREEZE PROTEIN
(uncultured
bacterium) 		4 / 7 TYR A 144
ILE A 173
GLY A 132
LEU A 137
 None
 0.99A 5esmA-6eioA:
undetectable		 5esmA-6eioA:
9.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VC0_A_RITA602_1
(CYTOCHROME P450 3A4)		 6eio ANTIFREEZE PROTEIN
(uncultured
bacterium) 		5 / 12 ASP A 225
LEU A 250
ALA A  55
ILE A 217
ALA A 218
 None
 1.10A 5vc0A-6eioA:
undetectable		 5vc0A-6eioA:
9.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBD_A_TRPA903_0
(PROTEIN ARGONAUTE-2)		 6eio ANTIFREEZE PROTEIN
(uncultured
bacterium) 		4 / 6 ILE A 171
GLN A 172
ILE A  50
ASP A 118
 None
 1.15A 6cbdA-6eioA:
undetectable		 6cbdA-6eioA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7L_B_Y00B405_1
(BETA-1 ADRENERGIC
RECEPTOR)		 6eio ANTIFREEZE PROTEIN
(uncultured
bacterium) 		4 / 6 GLY A  79
LEU A  80
VAL A 216
PHE A 206
 None
 0.96A 6h7lB-6eioA:
undetectable		 6h7lB-6eioA:
26.32