SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6ejb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KI3_B_PE2B2_1
(THYMIDINE KINASE)		 6ejb XYLOSYLTRANSFERASE 1
(Homo
sapiens) 		5 / 12 ILE A 608
ILE A 609
GLN A 341
ARG A 344
GLU A 607
 None
 1.40A 1ki3B-6ejbA:
undetectable		 1ki3B-6ejbA:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NP1_B_HSMB304_1
(NITROPHORIN 1)		 6ejb XYLOSYLTRANSFERASE 1
(Homo
sapiens) 		3 / 3 ASP A 764
LEU A 759
LEU A 760
 None
 0.80A 1np1B-6ejbA:
undetectable		 1np1B-6ejbA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE9_A_BEZA352_0
(D-AMINO ACID OXIDASE)		 6ejb XYLOSYLTRANSFERASE 1
(Homo
sapiens) 		4 / 5 TYR A 350
TYR A 356
ARG A 957
GLY A 956
 None
 0.92A 1ve9A-6ejbA:
undetectable		 1ve9A-6ejbA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_A_KLNA1501_1
(CYTOCHROME P450 3A4)		 6ejb XYLOSYLTRANSFERASE 1
(Homo
sapiens) 		5 / 10 PHE A 458
SER A 539
LEU A 525
THR A 524
GLY A 491
 None
 1.29A 2v0mA-6ejbA:
undetectable		 2v0mA-6ejbA:
9.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_C_ZMRC1776_1
(NEURAMINIDASE A)		 6ejb XYLOSYLTRANSFERASE 1
(Homo
sapiens) 		5 / 12 ARG A 957
ASP A 433
PHE A 330
LEU A 422
TYR A 617
 None
 1.48A 2ya7C-6ejbA:
undetectable		 2ya7C-6ejbA:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLB_B_TMQB612_1
(DHFR-TS)		 6ejb XYLOSYLTRANSFERASE 1
(Homo
sapiens) 		5 / 12 PHE A 596
ILE A 328
PHE A 418
ILE A 349
TYR A 617
 None
 1.21A 3clbB-6ejbA:
undetectable		 3clbB-6ejbA:
10.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_B_REMB350_2
(RENIN)		 6ejb XYLOSYLTRANSFERASE 1
(Homo
sapiens) 		4 / 4 VAL A 839
TYR A 867
PRO A 810
PHE A 837
 None
 1.28A 3d91B-6ejbA:
undetectable		 3d91B-6ejbA:
12.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL5_B_1UNB201_1
(PROTEASE)		 6ejb XYLOSYLTRANSFERASE 1
(Homo
sapiens) 		5 / 10 LEU A 469
ASP A 480
GLY A 261
ILE A 265
THR A 283
 None
 1.14A 3el5A-6ejbA:
undetectable		 3el5A-6ejbA:
27.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCO_A_CHDA3_0
(FERROCHELATASE,
MITOCHONDRIAL)		 6ejb XYLOSYLTRANSFERASE 1
(Homo
sapiens) 		4 / 4 LEU A 858
PRO A 762
LEU A 842
ARG A 847
 None
 1.45A 3hcoA-6ejbA:
undetectable		 3hcoA-6ejbA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_A_THHA642_1
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 6ejb XYLOSYLTRANSFERASE 1
(Homo
sapiens) 		3 / 3 ASN A 421
ASP A 426
ARG A 557
 None
 0.85A 3k13A-6ejbA:
undetectable		 3k13A-6ejbA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_2
(CARBONIC ANHYDRASE)		 6ejb XYLOSYLTRANSFERASE 1
(Homo
sapiens) 		3 / 3 GLN A 588
PHE A 584
TYR A 615
 None
 0.94A 3ucjB-6ejbA:
undetectable		 3ucjB-6ejbA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJ8_A_SUVA2001_2
(HUMAN OX1R FUSION
PROTEIN TO P.ABYSII
GLYCOGEN SYNTHASE)		 6ejb XYLOSYLTRANSFERASE 1
(Homo
sapiens) 		4 / 6 TRP A 555
HIS A 335
ILE A 568
VAL A 569
 None
 0.87A 4zj8A-6ejbA:
4.5		 4zj8A-6ejbA:
8.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_A_SAMA401_1
(PAVINE
N-METHYLTRANSFERASE)		 6ejb XYLOSYLTRANSFERASE 1
(Homo
sapiens) 		4 / 5 PHE A 508
SER A 509
ASN A 499
ASP A 444
 None
 1.42A 5kpcA-6ejbA:
undetectable		 5kpcA-6ejbA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9A_A_AR3A201_1
(PEPTIDYL-TRNA
HYDROLASE)		 6ejb XYLOSYLTRANSFERASE 1
(Homo
sapiens) 		4 / 6 ALA A 338
GLN A 341
GLN A 606
ASP A 693
 None
 1.09A 5y9aA-6ejbA:
undetectable		 5y9aA-6ejbA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_A_GLYA715_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 6ejb XYLOSYLTRANSFERASE 1
(Homo
sapiens) 		4 / 6 ASP A 944
SER A 947
ARG A 344
ARG A 340
 None
 1.06A 6dwdA-6ejbA:
undetectable
6dwdC-6ejbA:
undetectable		 6dwdA-6ejbA:
undetectable
6dwdC-6ejbA:
undetectable