SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6ejf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GS4_A_ZK5A1918_1
(ANDROGEN RECEPTOR)		 6ejf -
(-) 		5 / 12 LEU J 166
GLN J 174
TRP J 177
ALA J 216
LEU J 221
 None
 1.08A 1gs4A-6ejfJ:
undetectable		 1gs4A-6ejfJ:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WOP_A_FFOA2888_0
(AMINOMETHYLTRANSFERA
SE)		 6ejf -
(-) 		5 / 10 LEU J 183
LEU J 201
ILE J 178
GLU J 217
LEU J 215
 None
 1.09A 1wopA-6ejfJ:
undetectable		 1wopA-6ejfJ:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JST_A_HLTA101_1
(FOUR-ALPHA-HELIX
BUNDLE)		 6ejf -
(-) 		4 / 5 TRP J 291
ALA J 272
LEU J 246
ALA J 250
 None
 1.30A 2jstA-6ejfJ:
undetectable
2jstB-6ejfJ:
undetectable		 2jstA-6ejfJ:
undetectable
2jstB-6ejfJ:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NPN_A_SAMA4633_0
(PUTATIVE COBALAMIN
SYNTHESIS RELATED
PROTEIN)		 6ejf -
(-) 		5 / 9 GLY J 249
TYR J 284
ALA J 286
LEU J 221
LEU J 287
 None
 1.28A 2npnA-6ejfJ:
undetectable		 2npnA-6ejfJ:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 6ejf

(;
) 		4 / 8 LYS J 175
LEU G 431
ASP G 401
GLU J 217
 None
 1.10A 2zw9A-6ejfJ:
undetectable		 2zw9A-6ejfJ:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 6ejf -
(-) 		5 / 12 ILE G 471
ALA G 440
PRO G 405
ALA G 404
PRO G 400
 None
 1.07A 3jb3A-6ejfG:
undetectable		 3jb3A-6ejfG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_SAMA401_0
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 6ejf -
(-) 		5 / 12 ILE G 467
VAL G 444
LEU G 430
PRO G 459
VAL G 457
 None
 0.93A 4gc9A-6ejfG:
undetectable		 4gc9A-6ejfG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_G_SAMG301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 6ejf -
(-) 		5 / 12 ALA J 281
PRO J 267
PHE J 283
GLY J 220
GLU J 222
 None
 1.35A 5hfjG-6ejfJ:
undetectable		 5hfjG-6ejfJ:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TDZ_A_ADNA905_1
(ATP-CITRATE SYNTHASE)		 6ejf -
(-) 		4 / 6 ASP J 266
ARG J 199
LEU J 196
ASP J 195
 None
 1.15A 5tdzA-6ejfJ:
undetectable		 5tdzA-6ejfJ:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_B_SAMB401_0
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 6ejf -
(-) 		5 / 12 ALA G 404
PRO G 409
LYS G 451
ASP G 398
PRO G 402
 None
 1.34A 5zvgB-6ejfG:
undetectable		 5zvgB-6ejfG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_B_AQ4B602_1
(CYTOCHROME P450 1A1)		 6ejf -
(-) 		4 / 7 GLY G 403
ALA G 404
VAL G 444
LEU G 448
 None
 0.65A 6dwnB-6ejfG:
undetectable		 6dwnB-6ejfG:
undetectable