SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6ejg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EII_A_RTLA135_1
(CELLULAR
RETINOL-BINDING
PROTEIN II)		 6ejg SINGLE CHAIN FV
FRAGMENT
(Mus
musculus) 		4 / 7 GLN C 175
SER C 176
TYR C 263
GLN C  80
 None
 1.42A 1eiiA-6ejgC:
undetectable		 1eiiA-6ejgC:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H8S_A_AICA1000_1
(MUTANT AL2 6E7P9G)		 6ejg SINGLE CHAIN FV
FRAGMENT
(Mus
musculus) 		7 / 12 TYR C  78
PHE C 140
TRP C 202
ASN C 204
VAL C 206
ALA C 266
TRP C 279
 None
 0.66A 1h8sA-6ejgC:
31.3		 1h8sA-6ejgC:
19.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1IBG_H_OBNH1_2
(IGG2B-KAPPA 40-50
FAB (HEAVY CHAIN)
IGG2B-KAPPA 40-50
FAB (LIGHT CHAIN))		 6ejg SINGLE CHAIN FV
FRAGMENT
(Mus
musculus) 		4 / 7 THR C  69
SER C  70
SER C 133
ARG C 134
 None
 0.75A 1ibgL-6ejgC:
22.7		 1ibgL-6ejgC:
91.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KW0_A_H4BA429_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 6ejg SINGLE CHAIN FV
FRAGMENT
(Mus
musculus) 		5 / 12 VAL C 287
LEU C 252
LEU C 285
THR C 256
GLU C 215
 None
 1.30A 1kw0A-6ejgC:
undetectable		 1kw0A-6ejgC:
12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMT_A_H4BA1426_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 6ejg SINGLE CHAIN FV
FRAGMENT
(Mus
musculus) 		5 / 11 VAL C 287
LEU C 252
LEU C 285
THR C 256
GLU C 215
 None
 1.27A 1mmtA-6ejgC:
undetectable		 1mmtA-6ejgC:
12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q0Y_H_MOIH401_1
(FAB 9B1, HEAVY CHAIN
FAB 9B1, LIGHT CHAIN)		 6ejg SINGLE CHAIN FV
FRAGMENT
(Mus
musculus) 		4 / 7 TRP C 216
ILE C 228
LEU C 276
TRP C 202
 None
 1.26A 1q0yH-6ejgC:
15.8
1q0yL-6ejgC:
18.4		 1q0yH-6ejgC:
16.91
1q0yL-6ejgC:
17.67