SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6ejj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DIT_P_2PPP1_1
(ALPHA-THROMBIN
PEPTIDE INHIBITOR
CVS995)		 6ejj WLAC PROTEIN
(Campylobacter
jejuni) 		4 / 6 LEU A 262
ILE A 189
GLU A 275
PRO A 270
 None
None
UDP  A 401 (-2.7A)
NA  A 403 (-4.3A)
 1.13A 1ditH-6ejjA:
undetectable
1ditP-6ejjA:
undetectable		 1ditH-6ejjA:
15.81
1ditP-6ejjA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4007_1
(SERUM ALBUMIN)		 6ejj WLAC PROTEIN
(Campylobacter
jejuni) 		4 / 8 LEU A 317
ASN A 322
ASP A 209
LEU A 208
 None
 0.93A 1e7cA-6ejjA:
undetectable		 1e7cA-6ejjA:
8.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_A_URFA1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 6ejj WLAC PROTEIN
(Campylobacter
jejuni) 		4 / 6 ASN A 106
ILE A  37
SER A  86
THR A 111
 None
 1.06A 1h7xA-6ejjA:
2.2		 1h7xA-6ejjA:
6.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_B_URFB1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 6ejj WLAC PROTEIN
(Campylobacter
jejuni) 		4 / 6 ASN A 106
ILE A  37
SER A  86
THR A 111
 None
 1.08A 1h7xB-6ejjA:
2.8		 1h7xB-6ejjA:
6.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_C_URFC1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 6ejj WLAC PROTEIN
(Campylobacter
jejuni) 		4 / 6 ASN A 106
ILE A  37
SER A  86
THR A 111
 None
 1.07A 1h7xC-6ejjA:
2.9		 1h7xC-6ejjA:
6.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H7X_D_URFD1033_1
(DIHYDROPYRIMIDINE
DEHYDROGENASE)		 6ejj WLAC PROTEIN
(Campylobacter
jejuni) 		4 / 6 ASN A 106
ILE A  37
SER A  86
THR A 111
 None
 1.06A 1h7xD-6ejjA:
4.4		 1h7xD-6ejjA:
6.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDU_B_CIAB2003_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 6ejj WLAC PROTEIN
(Campylobacter
jejuni) 		5 / 12 ALA A 221
ILE A 220
ILE A 189
LEU A 313
MET A 200
 UDP  A 401 ( 4.0A)
None
None
None
None
 0.86A 1uduB-6ejjA:
undetectable		 1uduB-6ejjA:
12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOZ_A_CIAA501_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 6ejj WLAC PROTEIN
(Campylobacter
jejuni) 		5 / 12 ALA A 221
ILE A 220
ILE A 189
LEU A 313
MET A 200
 UDP  A 401 ( 4.0A)
None
None
None
None
 0.99A 1xozA-6ejjA:
undetectable		 1xozA-6ejjA:
11.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGN_A_PCFA1179_0
(WNT INHIBITORY
FACTOR 1)		 6ejj WLAC PROTEIN
(Campylobacter
jejuni) 		5 / 12 LEU A 165
ILE A 114
LEU A 113
ILE A  92
ILE A 103
 None
 1.14A 2ygnA-6ejjA:
undetectable		 2ygnA-6ejjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FW3_A_ETSA302_1
(CARBONIC ANHYDRASE 4)		 6ejj WLAC PROTEIN
(Campylobacter
jejuni) 		5 / 12 HIS A 169
VAL A  52
ILE A  36
VAL A  34
LEU A  21
 None
 0.81A 3fw3A-6ejjA:
undetectable		 3fw3A-6ejjA:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_B_NIOB5661_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 6ejj WLAC PROTEIN
(Campylobacter
jejuni) 		4 / 8 ILE A  36
ARG A  19
ASN A  26
THR A  23
 None
 0.91A 3hrdA-6ejjA:
undetectable
3hrdB-6ejjA:
undetectable		 3hrdA-6ejjA:
10.82
3hrdB-6ejjA:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_E_CLME221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6ejj WLAC PROTEIN
(Campylobacter
jejuni) 		3 / 3 PHE A 170
CYH A 168
HIS A 169
 None
 1.04A 3u9fF-6ejjA:
undetectable		 3u9fF-6ejjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_I_CLMI221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6ejj WLAC PROTEIN
(Campylobacter
jejuni) 		3 / 3 PHE A 170
CYH A 168
HIS A 169
 None
 1.08A 3u9fG-6ejjA:
undetectable		 3u9fG-6ejjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_K_CLMK221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6ejj WLAC PROTEIN
(Campylobacter
jejuni) 		3 / 3 PHE A 170
CYH A 168
HIS A 169
 None
 1.16A 3u9fL-6ejjA:
undetectable		 3u9fL-6ejjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_R_CLMR221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6ejj WLAC PROTEIN
(Campylobacter
jejuni) 		3 / 3 PHE A 170
CYH A 168
HIS A 169
 None
 1.06A 3u9fS-6ejjA:
undetectable		 3u9fS-6ejjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA503_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 6ejj WLAC PROTEIN
(Campylobacter
jejuni) 		4 / 6 ARG A 191
ILE A 189
VAL A 272
LEU A 262
 UDP  A 401 (-3.5A)
None
UDP  A 401 (-4.3A)
None
 1.10A 4em2A-6ejjA:
undetectable		 4em2A-6ejjA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I00_A_ZMRA509_2
(NEURAMINIDASE)		 6ejj WLAC PROTEIN
(Campylobacter
jejuni) 		4 / 5 LEU A  21
TRP A 350
ILE A 114
ASN A 106
 None
 1.49A 4i00A-6ejjA:
undetectable		 4i00A-6ejjA:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_A_ACTA502_0
(RNA-DEPENDENT RNA
POLYMERASE)		 6ejj WLAC PROTEIN
(Campylobacter
jejuni) 		4 / 5 LYS A 352
LEU A 353
GLU A 349
LEU A 164
 None
 1.09A 4k4yA-6ejjA:
undetectable		 4k4yA-6ejjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_E_ACTE503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 6ejj WLAC PROTEIN
(Campylobacter
jejuni) 		4 / 4 LYS A 352
LEU A 353
GLU A 349
LEU A 164
 None
 1.09A 4k4yE-6ejjA:
undetectable		 4k4yE-6ejjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_I_ACTI503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 6ejj WLAC PROTEIN
(Campylobacter
jejuni) 		4 / 5 LYS A 352
LEU A 353
GLU A 349
LEU A 164
 None
 1.10A 4k4yI-6ejjA:
undetectable		 4k4yI-6ejjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VNC_C_GCSC801_1
(GLYCOGEN [STARCH]
SYNTHASE ISOFORM 2)		 6ejj WLAC PROTEIN
(Campylobacter
jejuni) 		5 / 10 GLY A  16
HIS A 118
ASN A 166
LYS A 196
GLU A 267
 UDP  A 401 (-3.0A)
CL  A 404 ( 4.5A)
None
UDP  A 401 (-2.9A)
NA  A 403 (-3.6A)
 0.83A 5vncC-6ejjA:
24.4		 5vncC-6ejjA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_C_CHDC401_0
(BILE SALT HYDROLASE)		 6ejj WLAC PROTEIN
(Campylobacter
jejuni) 		4 / 8 LEU A  12
ILE A   8
LEU A  28
ALA A  25
 None
 0.82A 5y7pC-6ejjA:
undetectable		 5y7pC-6ejjA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_B_ACRB602_1
(-)		 6ejj WLAC PROTEIN
(Campylobacter
jejuni) 		5 / 12 GLU A  18
GLY A  15
GLY A  16
VAL A  20
ASN A 166
 A2G  A 406 ( 3.1A)
A2G  A 406 (-3.4A)
UDP  A 401 (-3.0A)
None
None
 0.69A 6gneB-6ejjA:
26.6		 6gneB-6ejjA:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_B_ACRB602_1
(-)		 6ejj WLAC PROTEIN
(Campylobacter
jejuni) 		5 / 12 GLU A  18
GLY A  16
VAL A  20
ASN A 166
ARG A 191
 A2G  A 406 ( 3.1A)
UDP  A 401 (-3.0A)
None
None
UDP  A 401 (-3.5A)
 0.93A 6gneB-6ejjA:
26.6		 6gneB-6ejjA:
9.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_2
(-)		 6ejj WLAC PROTEIN
(Campylobacter
jejuni) 		5 / 12 GLU A  18
GLY A  16
HIS A 118
ARG A 191
GLU A 267
 A2G  A 406 ( 3.1A)
UDP  A 401 (-3.0A)
CL  A 404 ( 4.5A)
UDP  A 401 (-3.5A)
NA  A 403 (-3.6A)
 1.02A 6gngA-6ejjA:
13.5		 6gngA-6ejjA:
9.22