SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6ejm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WOP_A_FFOA2887_1
(AMINOMETHYLTRANSFERA
SE)		 6ejm SINGLE CHAIN FV
FRAGMENT
(Mus
musculus) 		3 / 3 ASP H 142
GLU H  44
ARG H 110
 None
 0.65A 1wopA-6ejmH:
1.7		 1wopA-6ejmH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB512_1
(PHOSPHOLIPASE A2)		 6ejm SINGLE CHAIN FV
FRAGMENT
(Mus
musculus) 		4 / 5 VAL H  75
VAL H  86
THR H 138
ARG H  76
 None
 1.12A 3bjwA-6ejmH:
undetectable		 3bjwA-6ejmH:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_1
(PHOSPHOLIPASE A2)		 6ejm SINGLE CHAIN FV
FRAGMENT
(Mus
musculus) 		4 / 5 VAL H  75
VAL H  86
THR H 138
ARG H  76
 None
 1.21A 3bjwC-6ejmH:
undetectable		 3bjwC-6ejmH:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AE1_A_NCAA1536_0
(DIPHTHERIA TOXIN)		 6ejm SINGLE CHAIN FV
FRAGMENT
(Mus
musculus) 		4 / 6 GLY H 278
TYR H 265
ALA H 279
TYR H 266
 None
 0.98A 4ae1A-6ejmH:
3.3		 4ae1A-6ejmH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F5Z_A_BEZA302_0
(HALOALKANE
DEHALOGENASE)		 6ejm SINGLE CHAIN FV
FRAGMENT
(Mus
musculus) 		4 / 8 ASP H 142
TRP H 144
VAL H 237
LEU H 215
 None
 1.09A 4f5zA-6ejmH:
undetectable		 4f5zA-6ejmH:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIA_A_0U9A601_1
(CHOLESTEROL
24-HYDROXYLASE)		 6ejm SINGLE CHAIN FV
FRAGMENT
(Mus
musculus) 		5 / 12 LEU H 268
PHE H 277
ARG H 225
THR H  88
THR H 138
 None
 1.28A 4fiaA-6ejmH:
undetectable		 4fiaA-6ejmH:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIA_A_198A602_1
(CHOLESTEROL
24-HYDROXYLASE)		 6ejm SINGLE CHAIN FV
FRAGMENT
(Mus
musculus) 		5 / 12 LEU H 268
PHE H 277
ARG H 225
THR H  88
THR H 138
 None
 1.28A 4fiaA-6ejmH:
undetectable		 4fiaA-6ejmH:
12.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 6ejm SINGLE CHAIN FV
FRAGMENT
(Mus
musculus) 		5 / 12 ILE H 227
GLN H 180
TYR H 265
GLN H  77
LEU H  83
 None
 1.50A 4qztA-6ejmH:
undetectable		 4qztA-6ejmH:
undetectable