SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6ekg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ID5_B_SAMB301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 6ekg CHEMOTAXIS PROTEIN
CHEY
(Methanococcus
maripaludis) 		5 / 11 GLY Y  65
ASP Y  95
ALA Y  96
ASP Y  57
ILE Y  58
 None
None
None
MG  Y 201 (-2.5A)
None
 1.22A 3id5B-6ekgY:
undetectable		 3id5B-6ekgY:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ID5_F_SAMF301_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 6ekg CHEMOTAXIS PROTEIN
CHEY
(Methanococcus
maripaludis) 		5 / 11 GLY Y  65
ASP Y  95
ALA Y  96
ASP Y  57
ILE Y  58
 None
None
None
MG  Y 201 (-2.5A)
None
 1.23A 3id5F-6ekgY:
2.3		 3id5F-6ekgY:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 6ekg CHEMOTAXIS PROTEIN
CHEY
(Methanococcus
maripaludis) 		4 / 8 ILE Y  79
ILE Y  81
VAL Y  10
GLY Y  65
 None
 0.82A 4acaC-6ekgY:
8.1		 4acaC-6ekgY:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJE_A_TOYA202_1
(AADB)		 6ekg CHEMOTAXIS PROTEIN
CHEY
(Methanococcus
maripaludis) 		4 / 8 ASP Y  12
ASP Y  57
ASP Y  11
ILE Y 105
 MG  Y 201 (-2.6A)
MG  Y 201 (-2.5A)
MG  Y 201 ( 4.5A)
None
 0.96A 4xjeA-6ekgY:
undetectable		 4xjeA-6ekgY:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CFS_A_TOYA203_1
(AAD(2''),GENTAMICIN
2''-NUCLEOTIDYLTRANS
FERASE,GENTAMICIN
RESISTANCE PROTEIN)		 6ekg CHEMOTAXIS PROTEIN
CHEY
(Methanococcus
maripaludis) 		4 / 8 ASP Y  12
ASP Y  57
ASP Y  11
ILE Y 105
 MG  Y 201 (-2.6A)
MG  Y 201 (-2.5A)
MG  Y 201 ( 4.5A)
None
 1.00A 5cfsA-6ekgY:
undetectable		 5cfsA-6ekgY:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYB_A_KKKA508_1
(CYP51, STEROL
14ALPHA-DEMETHYLASE)		 6ekg CHEMOTAXIS PROTEIN
CHEY
(Methanococcus
maripaludis) 		5 / 12 PHE Y 118
PHE Y 109
PHE Y 122
ILE Y  33
LEU Y  24
 None
 1.19A 6aybA-6ekgY:
undetectable		 6aybA-6ekgY:
10.55