SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6eki'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AM6_A_HAEA555_1
(CARBONIC ANHYDRASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		7 / 7 HIS A 117
HIS A 119
HIS A 136
LEU A 201
THR A 202
THR A 203
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
ZN  A 301 (-4.4A)
None
None
 0.21A 1am6A-6ekiA:
29.8		 1am6A-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AM6_A_HAEA555_1
(CARBONIC ANHYDRASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 7 HIS A 119
HIS A 117
THR A 203
THR A 202
TRP A  33
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
None
ZN  A 301 (-4.4A)
None
 1.48A 1am6A-6ekiA:
29.8		 1am6A-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AM6_A_HAEA555_1
(CARBONIC ANHYDRASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		4 / 7 HIS A 119
HIS A 136
HIS A 117
THR A 202
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
ZN  A 301 (-3.3A)
ZN  A 301 (-4.4A)
 1.10A 1am6A-6ekiA:
29.8		 1am6A-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AM6_A_HAEA555_1
(CARBONIC ANHYDRASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		4 / 7 HIS A 136
HIS A 117
HIS A 119
THR A 203
 ZN  A 301 (-3.2A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
None
 1.06A 1am6A-6ekiA:
29.8		 1am6A-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AZM_A_AZMA262_1
(CARBONIC ANHYDRASE I)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 8 HIS A 117
HIS A 119
HIS A 136
LEU A 201
THR A 202
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
ZN  A 301 (-4.4A)
None
 0.23A 1azmA-6ekiA:
29.5		 1azmA-6ekiA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BZM_A_MZMA262_1
(CARBONIC ANHYDRASE I)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 8 HIS A 117
HIS A 119
HIS A 136
LEU A 201
THR A 202
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
ZN  A 301 (-4.4A)
None
 0.25A 1bzmA-6ekiA:
29.5		 1bzmA-6ekiA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CIL_A_ETSA263_1
(CARBONIC ANHYDRASE
II)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		11 / 12 HIS A  92
GLN A 115
HIS A 117
HIS A 119
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
None
 0.36A 1cilA-6ekiA:
29.9		 1cilA-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CIL_A_ETSA263_1
(CARBONIC ANHYDRASE
II)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		7 / 12 HIS A  92
HIS A 119
HIS A 136
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
ZN  A 301 (-4.4A)
None
None
 1.50A 1cilA-6ekiA:
29.9		 1cilA-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CIL_A_ETSA263_1
(CARBONIC ANHYDRASE
II)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 12 HIS A  92
HIS A 119
VAL A 138
LEU A 201
THR A 202
THR A 203
 None
ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
None
 1.14A 1cilA-6ekiA:
29.9		 1cilA-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMY_A_AZMA400_1
(MURINE CARBONIC
ANHYDRASE V)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		9 / 11 HIS A 117
HIS A 119
HIS A 136
VAL A 138
LEU A 146
LEU A 201
THR A 202
THR A 203
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
None
 0.34A 1dmyA-6ekiA:
26.9		 1dmyA-6ekiA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMY_A_AZMA400_1
(MURINE CARBONIC
ANHYDRASE V)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 11 HIS A 136
HIS A 117
HIS A 119
TYR A 197
THR A 203
 ZN  A 301 (-3.2A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
None
None
 1.15A 1dmyA-6ekiA:
26.9		 1dmyA-6ekiA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMY_B_AZMB900_1
(MURINE CARBONIC
ANHYDRASE V)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		10 / 12 GLN A 115
HIS A 117
HIS A 119
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
None
 0.35A 1dmyB-6ekiA:
26.9		 1dmyB-6ekiA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMY_B_AZMB900_1
(MURINE CARBONIC
ANHYDRASE V)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 12 HIS A 119
HIS A 136
LEU A 201
THR A 202
THR A 203
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
ZN  A 301 (-4.4A)
None
None
 1.49A 1dmyB-6ekiA:
26.9		 1dmyB-6ekiA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMY_B_AZMB900_1
(MURINE CARBONIC
ANHYDRASE V)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 12 HIS A 119
VAL A 138
LEU A 201
THR A 202
THR A 203
 ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
None
 0.76A 1dmyB-6ekiA:
26.9		 1dmyB-6ekiA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMY_B_AZMB900_1
(MURINE CARBONIC
ANHYDRASE V)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 12 HIS A 136
HIS A 117
HIS A 119
TYR A 197
THR A 203
 ZN  A 301 (-3.2A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
None
None
 1.13A 1dmyB-6ekiA:
26.9		 1dmyB-6ekiA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSG_B_MK1B902_1
(HIV-1 PROTEASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 10 ARG A 247
ILE A 152
GLY A 150
PRO A  62
VAL A  63
ILE A  65
 None
 1.28A 1hsgA-6ekiA:
undetectable		 1hsgA-6ekiA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JD0_A_AZMA1400_1
(CARBONIC ANHYDRASE
XII)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		9 / 9 GLN A 115
HIS A 117
HIS A 119
HIS A 136
VAL A 138
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
ZN  A 301 (-4.4A)
None
None
 0.42A 1jd0A-6ekiA:
29.5		 1jd0A-6ekiA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JD0_B_AZMB2401_1
(CARBONIC ANHYDRASE
XII)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		7 / 11 GLN A 115
HIS A 117
GLU A 134
HIS A 136
VAL A 138
VAL A 148
TRP A 212
 None
ZN  A 301 (-3.3A)
None
ZN  A 301 (-3.2A)
None
None
None
 1.46A 1jd0B-6ekiA:
29.2		 1jd0B-6ekiA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JD0_B_AZMB2401_1
(CARBONIC ANHYDRASE
XII)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		11 / 11 GLN A 115
HIS A 117
HIS A 119
GLU A 123
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
None
 0.42A 1jd0B-6ekiA:
29.2		 1jd0B-6ekiA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JD0_B_AZMB2401_1
(CARBONIC ANHYDRASE
XII)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 11 HIS A 119
GLU A 123
VAL A 138
LEU A 201
THR A 202
THR A 203
 ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
None
None
ZN  A 301 (-4.4A)
None
 0.98A 1jd0B-6ekiA:
29.2		 1jd0B-6ekiA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OQ5_A_CELA701_1
(CARBONIC ANHYDRASE
II)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 12 ASN A  90
HIS A 119
LEU A 201
THR A 202
PRO A 205
 None
ZN  A 301 (-3.3A)
None
ZN  A 301 (-4.4A)
None
 1.02A 1oq5A-6ekiA:
30.2		 1oq5A-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OQ5_A_CELA701_1
(CARBONIC ANHYDRASE
II)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		8 / 12 GLN A 115
HIS A 117
HIS A 119
VAL A 138
LEU A 201
THR A 202
PRO A 205
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
None
None
 0.30A 1oq5A-6ekiA:
30.2		 1oq5A-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS6_A_DXCA75_0
(PPCA)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		4 / 8 ILE A 162
LEU A 187
PHE A 116
GLY A  84
 None
 0.89A 1os6A-6ekiA:
undetectable		 1os6A-6ekiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJ6_A_AZMA400_1
(CARBONIC ANHYDRASE
XIV)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		9 / 10 GLN A 115
HIS A 117
HIS A 119
HIS A 136
VAL A 138
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
ZN  A 301 (-4.4A)
None
None
 0.35A 1rj6A-6ekiA:
29.2		 1rj6A-6ekiA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJ6_B_AZMB401_1
(CARBONIC ANHYDRASE
XIV)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		9 / 10 GLN A 115
HIS A 117
HIS A 119
HIS A 136
VAL A 138
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
ZN  A 301 (-4.4A)
None
None
 0.35A 1rj6B-6ekiA:
29.1		 1rj6B-6ekiA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDT_B_MK1B902_1
(PROTEASE RETROPEPSIN)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 10 ARG A 247
ILE A 152
GLY A 150
PRO A  62
VAL A  63
ILE A  65
 None
 1.22A 1sdtA-6ekiA:
undetectable		 1sdtA-6ekiA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDU_B_MK1B902_1
(PROTEASE RETROPEPSIN)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 11 ARG A 247
ILE A 152
GLY A 150
VAL A  63
ILE A  65
 None
 0.92A 1sduA-6ekiA:
undetectable		 1sduA-6ekiA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDU_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 12 ARG A 247
ILE A 152
GLY A 150
VAL A  63
ILE A  65
 None
 0.84A 1sduB-6ekiA:
undetectable		 1sduB-6ekiA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YDA_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		8 / 10 GLN A 115
HIS A 117
HIS A 136
VAL A 138
VAL A 148
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
ZN  A 301 (-4.4A)
None
None
 0.31A 1ydaA-6ekiA:
29.7		 1ydaA-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YDB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		9 / 11 GLN A 115
HIS A 117
HIS A 119
HIS A 136
VAL A 138
VAL A 148
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
ZN  A 301 (-4.4A)
None
None
 0.23A 1ydbA-6ekiA:
29.8		 1ydbA-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YDB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 11 HIS A 119
HIS A 136
THR A 202
THR A 203
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
ZN  A 301 (-4.4A)
None
None
 1.48A 1ydbA-6ekiA:
29.8		 1ydbA-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YDD_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		8 / 10 GLN A 115
HIS A 117
HIS A 119
HIS A 136
VAL A 138
VAL A 148
THR A 202
THR A 203
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
ZN  A 301 (-4.4A)
None
 0.22A 1yddA-6ekiA:
30.0		 1yddA-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YDD_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 10 HIS A 119
HIS A 117
VAL A 138
THR A 202
THR A 203
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
None
ZN  A 301 (-4.4A)
None
 1.42A 1yddA-6ekiA:
30.0		 1yddA-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9Y_A_FUNA500_1
(CARBONIC ANHYDRASE
II)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		9 / 12 GLN A 115
HIS A 117
HIS A 119
VAL A 138
VAL A 148
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
None
None
None
ZN  A 301 (-4.4A)
None
None
 0.33A 1z9yA-6ekiA:
29.9		 1z9yA-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9Y_A_FUNA500_1
(CARBONIC ANHYDRASE
II)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 12 HIS A 119
VAL A 138
LEU A 201
THR A 202
THR A 203
 ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
None
 0.90A 1z9yA-6ekiA:
29.9		 1z9yA-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZGF_A_TRUA300_1
(CARBONIC ANHYDRASE
II)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 12 ASN A  90
HIS A 119
VAL A 138
LEU A 201
THR A 202
THR A 203
 None
ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
None
 1.03A 1zgfA-6ekiA:
30.1		 1zgfA-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZGF_A_TRUA300_1
(CARBONIC ANHYDRASE
II)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		10 / 12 GLN A 115
HIS A 117
HIS A 119
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
None
 0.27A 1zgfA-6ekiA:
30.1		 1zgfA-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZGF_A_TRUA300_1
(CARBONIC ANHYDRASE
II)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 12 HIS A 119
HIS A 136
LEU A 201
THR A 202
THR A 203
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
ZN  A 301 (-4.4A)
None
None
 1.45A 1zgfA-6ekiA:
30.1		 1zgfA-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZSB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		7 / 12 GLN A 115
HIS A 117
GLU A 134
HIS A 136
VAL A 138
VAL A 148
TRP A 212
 None
ZN  A 301 (-3.3A)
None
ZN  A 301 (-3.2A)
None
None
None
 1.42A 1zsbA-6ekiA:
30.1		 1zsbA-6ekiA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZSB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		11 / 12 GLN A 115
HIS A 117
HIS A 119
GLU A 123
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
None
 0.32A 1zsbA-6ekiA:
30.1		 1zsbA-6ekiA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZSB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 12 HIS A 119
GLU A 123
VAL A 138
LEU A 201
THR A 202
THR A 203
 ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
None
None
ZN  A 301 (-4.4A)
None
 0.96A 1zsbA-6ekiA:
30.1		 1zsbA-6ekiA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZSB_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 12 HIS A 119
HIS A 136
LEU A 201
THR A 202
THR A 203
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
ZN  A 301 (-4.4A)
None
None
 1.48A 1zsbA-6ekiA:
30.1		 1zsbA-6ekiA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVO_B_MK1B902_1
(POL POLYPROTEIN)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 9 ARG A 247
ILE A 152
GLY A 150
VAL A  63
ILE A  65
 None
 0.92A 2avoA-6ekiA:
undetectable		 2avoA-6ekiA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AW1_A_COXA264_1
(CARBONIC ANHYDRASE
II)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		10 / 12 GLN A 115
HIS A 117
HIS A 119
VAL A 138
LEU A 146
VAL A 148
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
None
None
None
None
ZN  A 301 (-4.4A)
None
None
 0.31A 2aw1A-6ekiA:
29.9		 2aw1A-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AW1_A_COXA264_1
(CARBONIC ANHYDRASE
II)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 12 HIS A 119
LEU A 146
VAL A 138
LEU A 201
THR A 202
THR A 203
 ZN  A 301 (-3.3A)
None
None
None
ZN  A 301 (-4.4A)
None
 1.17A 2aw1A-6ekiA:
29.9		 2aw1A-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EZ7_A_DHIA301_0
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		4 / 6 TRP A  33
GLN A 115
THR A 203
PRO A 205
 None
 0.51A 2ez7A-6ekiA:
29.5		 2ez7A-6ekiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GEH_A_NHYA300_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		8 / 8 HIS A 117
HIS A 119
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
 0.29A 2gehA-6ekiA:
29.8		 2gehA-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H4N_A_AZMA264_1
(CARBONIC ANHYDRASE
II)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		7 / 9 GLN A 115
HIS A 119
HIS A 136
VAL A 138
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
ZN  A 301 (-4.4A)
None
None
 0.45A 2h4nA-6ekiA:
29.9		 2h4nA-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HKK_A_ALEA300_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		4 / 6 ASN A  90
HIS A  92
GLN A 115
THR A 203
 None
 0.46A 2hkkA-6ekiA:
29.9		 2hkkA-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IT4_A_PPFA500_1
(CARBONIC ANHYDRASE 1)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 8 HIS A 117
HIS A 119
HIS A 136
VAL A 148
LEU A 201
THR A 202
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
ZN  A 301 (-4.4A)
 0.30A 2it4A-6ekiA:
29.8		 2it4A-6ekiA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IT4_A_PPFA500_1
(CARBONIC ANHYDRASE 1)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		4 / 8 HIS A 119
VAL A 138
LEU A 201
THR A 202
 ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
 0.82A 2it4A-6ekiA:
29.8		 2it4A-6ekiA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4S_A_AB1A400_2
(PROTEASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 12 ARG A 247
ILE A 152
GLY A 150
VAL A  63
ILE A  65
 None
 0.85A 2o4sB-6ekiA:
undetectable		 2o4sB-6ekiA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2POU_A_I7AA1000_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 12 ASN A  90
HIS A 119
VAL A 138
LEU A 201
THR A 202
THR A 203
 None
ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
None
 1.04A 2pouA-6ekiA:
29.8		 2pouA-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2POU_A_I7AA1000_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		9 / 12 GLN A 115
HIS A 117
HIS A 119
VAL A 138
VAL A 148
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
None
None
None
ZN  A 301 (-4.4A)
None
None
 0.26A 2pouA-6ekiA:
29.8		 2pouA-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 12 ARG A 247
ILE A 152
GLY A 150
VAL A  63
ILE A  65
 None
 0.89A 2pymB-6ekiA:
undetectable		 2pymB-6ekiA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 12 ARG A 247
ILE A 152
GLY A 150
VAL A  63
ILE A  65
 None
 0.89A 2pynB-6ekiA:
undetectable		 2pynB-6ekiA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 12 ARG A 247
ILE A 152
GLY A 150
VAL A  63
ILE A  65
 None
 0.91A 2q63B-6ekiA:
undetectable		 2q63B-6ekiA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 12 ARG A 247
ILE A 152
GLY A 150
VAL A  63
ILE A  65
 None
 0.86A 2qakB-6ekiA:
undetectable		 2qakB-6ekiA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_B_MK1B902_1
(PROTEASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 12 ARG A 247
ILE A 152
GLY A 150
VAL A  63
ILE A  65
 None
 0.87A 2r5pA-6ekiA:
undetectable		 2r5pA-6ekiA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_D_MK1D902_1
(PROTEASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 12 ARG A 247
ILE A 152
GLY A 150
VAL A  63
ILE A  65
 None
 0.86A 2r5pC-6ekiA:
undetectable		 2r5pC-6ekiA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_B_1UNB900_1
(PROTEASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 9 ARG A 247
ILE A 152
GLY A 150
PRO A  62
VAL A  63
ILE A  65
 None
 1.27A 2r5qA-6ekiA:
undetectable		 2r5qA-6ekiA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_D_1UND900_1
(PROTEASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 9 ARG A 247
ILE A 152
GLY A 150
PRO A  62
VAL A  63
ILE A  65
 None
 1.27A 2r5qC-6ekiA:
undetectable		 2r5qC-6ekiA:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_A_ASDA1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		4 / 8 ILE A 182
GLY A  84
PHE A 116
PHE A 118
 None
 0.64A 2vctA-6ekiA:
undetectable		 2vctA-6ekiA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_B_ASDB1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		4 / 8 ILE A 182
GLY A  84
PHE A 116
PHE A 118
 None
 0.62A 2vctB-6ekiA:
undetectable		 2vctB-6ekiA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_C_ASDC1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		4 / 8 ILE A 182
GLY A  84
PHE A 116
PHE A 118
 None
 0.88A 2vctC-6ekiA:
undetectable		 2vctC-6ekiA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_D_ASDD1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		4 / 7 ILE A 182
GLY A  84
PHE A 116
PHE A 118
 None
 0.59A 2vctD-6ekiA:
undetectable		 2vctD-6ekiA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BL1_A_BL1A300_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		10 / 12 ASN A  90
GLN A 115
HIS A 117
HIS A 119
HIS A 136
VAL A 148
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
ZN  A 301 (-4.4A)
None
None
 0.38A 3bl1A-6ekiA:
29.8		 3bl1A-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BL1_A_BL1A300_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 12 HIS A 119
HIS A 136
LEU A 201
THR A 202
THR A 203
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
ZN  A 301 (-4.4A)
None
None
 1.48A 3bl1A-6ekiA:
29.8		 3bl1A-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BL1_A_BL1A300_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 12 HIS A 119
VAL A 138
LEU A 201
THR A 202
THR A 203
 ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
None
 0.92A 3bl1A-6ekiA:
29.8		 3bl1A-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CAJ_A_EZLA265_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		9 / 10 HIS A 117
HIS A 119
HIS A 136
VAL A 138
LEU A 201
THR A 202
THR A 203
PRO A 205
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
ZN  A 301 (-4.4A)
None
None
None
 0.25A 3cajA-6ekiA:
29.9		 3cajA-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CAJ_A_EZLA265_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 10 HIS A 119
VAL A 148
LEU A 201
THR A 203
PRO A 205
 ZN  A 301 (-3.3A)
None
None
None
None
 0.96A 3cajA-6ekiA:
29.9		 3cajA-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZV_A_AZMA263_1
(CARBONIC ANHYDRASE
13)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		9 / 12 GLN A 115
HIS A 117
HIS A 119
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
 0.50A 3czvA-6ekiA:
30.2
3czvB-6ekiA:
30.2		 3czvA-6ekiA:
19.07
3czvB-6ekiA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZV_B_AZMB263_1
(CARBONIC ANHYDRASE
13)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		9 / 10 GLN A 115
HIS A 117
HIS A 119
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
 0.45A 3czvB-6ekiA:
30.2		 3czvB-6ekiA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZV_B_AZMB263_1
(CARBONIC ANHYDRASE
13)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 10 GLN A 115
HIS A 117
HIS A 136
LEU A 146
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
 1.48A 3czvB-6ekiA:
30.2		 3czvB-6ekiA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZV_B_AZMB263_1
(CARBONIC ANHYDRASE
13)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 10 HIS A 119
HIS A 136
LEU A 201
THR A 202
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
ZN  A 301 (-4.4A)
None
 1.49A 3czvB-6ekiA:
30.2		 3czvB-6ekiA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DAZ_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		9 / 10 GLN A 115
HIS A 117
HIS A 119
HIS A 136
VAL A 138
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
ZN  A 301 (-4.4A)
None
None
 0.29A 3dazA-6ekiA:
30.0		 3dazA-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DAZ_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 10 GLN A 115
HIS A 117
HIS A 136
LEU A 146
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
 1.48A 3dazA-6ekiA:
30.0		 3dazA-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DAZ_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 10 HIS A 119
HIS A 136
LEU A 201
THR A 202
THR A 203
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
ZN  A 301 (-4.4A)
None
None
 1.50A 3dazA-6ekiA:
30.0		 3dazA-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DAZ_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 10 HIS A 136
HIS A 119
VAL A 148
LEU A 201
THR A 203
 ZN  A 301 (-3.2A)
ZN  A 301 (-3.3A)
None
None
None
 1.42A 3dazA-6ekiA:
30.0		 3dazA-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DC3_A_AZMA263_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		7 / 12 GLN A 115
HIS A 117
GLU A 134
HIS A 136
VAL A 138
VAL A 148
TRP A 212
 None
ZN  A 301 (-3.3A)
None
ZN  A 301 (-3.2A)
None
None
None
 1.45A 3dc3A-6ekiA:
30.0		 3dc3A-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DC3_A_AZMA263_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		11 / 12 GLN A 115
HIS A 117
HIS A 119
GLU A 123
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
None
 0.32A 3dc3A-6ekiA:
30.0		 3dc3A-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DC3_A_AZMA263_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 12 HIS A 119
GLU A 123
VAL A 138
LEU A 201
THR A 202
THR A 203
 ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
None
None
ZN  A 301 (-4.4A)
None
 0.97A 3dc3A-6ekiA:
30.0		 3dc3A-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCS_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		9 / 10 GLN A 115
HIS A 117
HIS A 119
HIS A 136
VAL A 138
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
ZN  A 301 (-4.4A)
None
None
 0.37A 3dcsA-6ekiA:
30.0		 3dcsA-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCS_A_MZMA263_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 10 HIS A 136
HIS A 119
VAL A 148
LEU A 201
THR A 203
 ZN  A 301 (-3.2A)
ZN  A 301 (-3.3A)
None
None
None
 1.40A 3dcsA-6ekiA:
30.0		 3dcsA-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		10 / 10 HIS A 117
HIS A 119
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
THR A 203
PRO A 205
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
None
None
 0.25A 3dcwA-6ekiA:
30.0		 3dcwA-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		7 / 10 HIS A 119
HIS A 136
LEU A 201
THR A 202
THR A 203
PRO A 205
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
ZN  A 301 (-4.4A)
None
None
None
 1.47A 3dcwA-6ekiA:
30.0		 3dcwA-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCW_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 10 HIS A 119
VAL A 138
LEU A 201
THR A 202
THR A 203
PRO A 205
 ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
None
None
 0.88A 3dcwA-6ekiA:
30.0		 3dcwA-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD0_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		10 / 10 HIS A 117
HIS A 119
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
THR A 203
PRO A 205
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
None
None
 0.25A 3dd0A-6ekiA:
29.9		 3dd0A-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD0_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		7 / 10 HIS A 119
HIS A 136
LEU A 201
THR A 202
THR A 203
PRO A 205
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
ZN  A 301 (-4.4A)
None
None
None
 1.44A 3dd0A-6ekiA:
29.9		 3dd0A-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD0_A_EZLA301_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 10 HIS A 119
VAL A 138
LEU A 201
THR A 202
THR A 203
PRO A 205
 ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
None
None
 0.88A 3dd0A-6ekiA:
29.9		 3dd0A-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKX_B_1UNB201_2
(PROTEASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 11 ARG A 247
ILE A 152
GLY A 150
PRO A  62
VAL A  63
ILE A  65
 None
 1.36A 3ekxB-6ekiA:
undetectable		 3ekxB-6ekiA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKY_A_DR7A100_2
(PROTEASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 9 ILE A 152
GLY A 150
PRO A  62
VAL A  63
ILE A  65
 None
 1.22A 3ekyB-6ekiA:
undetectable		 3ekyB-6ekiA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F4X_A_KLTA300_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		11 / 12 ASN A  90
GLN A 115
HIS A 117
HIS A 119
VAL A 138
VAL A 148
LEU A 201
THR A 202
THR A 203
PRO A 205
TRP A 212
 None
None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
None
None
None
ZN  A 301 (-4.4A)
None
None
None
 0.40A 3f4xA-6ekiA:
29.8		 3f4xA-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F4X_A_KLTA300_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		7 / 12 ASN A  90
HIS A 119
VAL A 138
LEU A 201
THR A 202
THR A 203
PRO A 205
 None
ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
None
None
 1.05A 3f4xA-6ekiA:
29.8		 3f4xA-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F4X_A_KLTA300_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		7 / 12 HIS A 117
HIS A 119
VAL A 148
LEU A 201
THR A 202
THR A 203
PRO A 205
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
None
None
 1.07A 3f4xA-6ekiA:
29.8		 3f4xA-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F4X_A_KLTA300_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 12 HIS A 119
LEU A 201
THR A 202
THR A 203
PRO A 205
TRP A 212
 ZN  A 301 (-3.3A)
None
ZN  A 301 (-4.4A)
None
None
None
 1.33A 3f4xA-6ekiA:
29.8		 3f4xA-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FW3_A_ETSA302_1
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		10 / 12 ASN A  90
GLN A 115
HIS A 117
HIS A 119
VAL A 138
VAL A 148
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
None
None
None
ZN  A 301 (-4.4A)
None
None
 0.55A 3fw3A-6ekiA:
27.0		 3fw3A-6ekiA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FW3_A_ETSA302_1
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		10 / 12 ASN A  90
HIS A  92
HIS A 117
HIS A 119
VAL A 138
VAL A 148
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
None
None
None
ZN  A 301 (-4.4A)
None
None
 0.50A 3fw3A-6ekiA:
27.0		 3fw3A-6ekiA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FW3_A_ETSA302_1
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 12 HIS A  92
HIS A 119
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
None
ZN  A 301 (-4.4A)
None
None
 1.34A 3fw3A-6ekiA:
27.0		 3fw3A-6ekiA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FW3_A_ETSA302_1
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 12 HIS A  92
HIS A 119
VAL A 138
LEU A 201
THR A 202
THR A 203
 None
ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
None
 1.04A 3fw3A-6ekiA:
27.0		 3fw3A-6ekiA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FW3_B_ETSB303_1
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		11 / 12 ASN A  90
GLN A 115
HIS A 117
HIS A 119
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
None
 0.43A 3fw3B-6ekiA:
26.8		 3fw3B-6ekiA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FW3_B_ETSB303_1
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 12 HIS A 119
VAL A 138
LEU A 201
THR A 202
THR A 203
 ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
None
 0.92A 3fw3B-6ekiA:
26.8		 3fw3B-6ekiA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HKU_A_TORA300_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		9 / 12 ASN A  90
GLN A 115
HIS A 117
HIS A 119
VAL A 138
VAL A 148
LEU A 201
THR A 203
TRP A 212
 None
None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
None
None
None
None
None
 0.30A 3hkuA-6ekiA:
29.7		 3hkuA-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HKU_A_TORA300_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 12 ASN A  90
HIS A 119
VAL A 138
LEU A 201
THR A 203
 None
ZN  A 301 (-3.3A)
None
None
None
 1.00A 3hkuA-6ekiA:
29.7		 3hkuA-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HKU_A_TORA300_2
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		3 / 3 GLU A 123
HIS A 136
THR A 202
 ZN  A 301 ( 4.7A)
ZN  A 301 (-3.2A)
ZN  A 301 (-4.4A)
 0.20A 3hkuA-6ekiA:
29.7		 3hkuA-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS4_A_AZMA701_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		10 / 11 GLN A 115
HIS A 117
HIS A 119
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
None
 0.22A 3hs4A-6ekiA:
30.2		 3hs4A-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS4_A_AZMA701_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 11 HIS A 119
HIS A 136
LEU A 201
THR A 202
THR A 203
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
ZN  A 301 (-4.4A)
None
None
 1.46A 3hs4A-6ekiA:
30.2		 3hs4A-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS4_A_AZMA701_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 11 HIS A 119
VAL A 138
LEU A 201
THR A 202
THR A 203
 ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
None
 0.90A 3hs4A-6ekiA:
30.2		 3hs4A-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAI_A_AZMA263_1
(CARBONIC ANHYDRASE 9)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 11 GLN A 115
HIS A 117
GLU A 134
HIS A 136
VAL A 138
TRP A 212
 None
ZN  A 301 (-3.3A)
None
ZN  A 301 (-3.2A)
None
None
 1.46A 3iaiA-6ekiA:
29.0		 3iaiA-6ekiA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAI_A_AZMA263_1
(CARBONIC ANHYDRASE 9)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 11 GLN A 115
HIS A 117
GLU A 134
VAL A 138
THR A 202
 None
ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
 1.15A 3iaiA-6ekiA:
29.0		 3iaiA-6ekiA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAI_A_AZMA263_1
(CARBONIC ANHYDRASE 9)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		10 / 11 GLN A 115
HIS A 117
HIS A 119
GLU A 123
HIS A 136
VAL A 138
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
ZN  A 301 (-3.2A)
None
None
ZN  A 301 (-4.4A)
None
None
 0.29A 3iaiA-6ekiA:
29.0		 3iaiA-6ekiA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAI_A_AZMA263_1
(CARBONIC ANHYDRASE 9)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 11 HIS A 119
GLU A 123
VAL A 148
LEU A 201
THR A 203
 ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
None
None
None
 0.91A 3iaiA-6ekiA:
29.0		 3iaiA-6ekiA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAI_B_AZMB263_1
(CARBONIC ANHYDRASE 9)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 11 GLN A 115
HIS A 117
GLU A 134
HIS A 136
VAL A 138
TRP A 212
 None
ZN  A 301 (-3.3A)
None
ZN  A 301 (-3.2A)
None
None
 1.46A 3iaiB-6ekiA:
29.2		 3iaiB-6ekiA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAI_B_AZMB263_1
(CARBONIC ANHYDRASE 9)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 11 GLN A 115
HIS A 117
GLU A 134
VAL A 138
THR A 202
 None
ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
 1.16A 3iaiB-6ekiA:
29.2		 3iaiB-6ekiA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAI_B_AZMB263_1
(CARBONIC ANHYDRASE 9)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		10 / 11 GLN A 115
HIS A 117
HIS A 119
GLU A 123
HIS A 136
VAL A 138
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
ZN  A 301 (-3.2A)
None
None
ZN  A 301 (-4.4A)
None
None
 0.29A 3iaiB-6ekiA:
29.2		 3iaiB-6ekiA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAI_B_AZMB263_1
(CARBONIC ANHYDRASE 9)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 11 HIS A 119
GLU A 123
VAL A 148
LEU A 201
THR A 203
 ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
None
None
None
 0.90A 3iaiB-6ekiA:
29.2		 3iaiB-6ekiA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAI_C_AZMC263_1
(CARBONIC ANHYDRASE 9)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 11 GLN A 115
HIS A 117
GLU A 134
HIS A 136
VAL A 138
TRP A 212
 None
ZN  A 301 (-3.3A)
None
ZN  A 301 (-3.2A)
None
None
 1.47A 3iaiC-6ekiA:
29.2		 3iaiC-6ekiA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAI_C_AZMC263_1
(CARBONIC ANHYDRASE 9)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 11 GLN A 115
HIS A 117
GLU A 134
VAL A 138
THR A 202
 None
ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
 1.16A 3iaiC-6ekiA:
29.2		 3iaiC-6ekiA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAI_C_AZMC263_1
(CARBONIC ANHYDRASE 9)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		10 / 11 GLN A 115
HIS A 117
HIS A 119
GLU A 123
HIS A 136
VAL A 138
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
ZN  A 301 (-3.2A)
None
None
ZN  A 301 (-4.4A)
None
None
 0.27A 3iaiC-6ekiA:
29.2		 3iaiC-6ekiA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAI_C_AZMC263_1
(CARBONIC ANHYDRASE 9)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 11 HIS A 119
GLU A 123
VAL A 148
LEU A 201
THR A 203
 ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
None
None
None
 0.90A 3iaiC-6ekiA:
29.2		 3iaiC-6ekiA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAI_D_AZMD263_1
(CARBONIC ANHYDRASE 9)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 11 GLN A 115
HIS A 117
GLU A 134
HIS A 136
VAL A 138
TRP A 212
 None
ZN  A 301 (-3.3A)
None
ZN  A 301 (-3.2A)
None
None
 1.46A 3iaiD-6ekiA:
29.2		 3iaiD-6ekiA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAI_D_AZMD263_1
(CARBONIC ANHYDRASE 9)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 11 GLN A 115
HIS A 117
GLU A 134
VAL A 138
THR A 202
 None
ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
 1.16A 3iaiD-6ekiA:
29.2		 3iaiD-6ekiA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAI_D_AZMD263_1
(CARBONIC ANHYDRASE 9)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		10 / 11 GLN A 115
HIS A 117
HIS A 119
GLU A 123
HIS A 136
VAL A 138
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
ZN  A 301 (-3.2A)
None
None
ZN  A 301 (-4.4A)
None
None
 0.28A 3iaiD-6ekiA:
29.2		 3iaiD-6ekiA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAI_D_AZMD263_1
(CARBONIC ANHYDRASE 9)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 11 HIS A 119
GLU A 123
VAL A 148
LEU A 201
THR A 203
 ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
None
None
None
 0.88A 3iaiD-6ekiA:
29.2		 3iaiD-6ekiA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KWA_A_SPMA300_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		10 / 11 GLN A 115
HIS A 117
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
THR A 203
PRO A 205
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
None
None
 0.34A 3kwaA-6ekiA:
29.8		 3kwaA-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KWA_A_SPMA300_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		7 / 11 HIS A 117
HIS A 136
VAL A 148
LEU A 201
THR A 202
PRO A 204
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
ZN  A 301 (-4.4A)
None
None
 1.36A 3kwaA-6ekiA:
29.8		 3kwaA-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KWA_A_SPMA300_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		7 / 11 HIS A 119
HIS A 136
LEU A 201
THR A 202
THR A 203
PRO A 205
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
ZN  A 301 (-4.4A)
None
None
None
 1.44A 3kwaA-6ekiA:
29.8		 3kwaA-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXE_A_TORA262_1
(CARBONIC ANHYDRASE 1)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		7 / 12 GLN A 115
HIS A 117
HIS A 119
VAL A 148
LEU A 201
THR A 202
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
None
 0.50A 3lxeA-6ekiA:
30.1		 3lxeA-6ekiA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXE_B_TORB262_1
(CARBONIC ANHYDRASE 1)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		7 / 12 GLN A 115
HIS A 117
HIS A 119
VAL A 148
LEU A 201
THR A 202
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
None
 0.50A 3lxeB-6ekiA:
30.1		 3lxeB-6ekiA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZV_A_017A200_2
(HIV-1 PROTEASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 11 ARG A 247
ILE A 152
GLY A 150
PRO A  62
VAL A  63
ILE A  65
 None
 1.27A 3lzvB-6ekiA:
undetectable		 3lzvB-6ekiA:
24.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		10 / 11 HIS A 117
HIS A 119
GLU A 123
HIS A 136
VAL A 138
LEU A 201
THR A 202
THR A 203
PRO A 205
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
ZN  A 301 (-3.2A)
None
None
ZN  A 301 (-4.4A)
None
None
None
 0.25A 3mdzA-6ekiA:
29.4		 3mdzA-6ekiA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 11 HIS A 119
GLU A 123
VAL A 148
LEU A 201
THR A 203
PRO A 205
 ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
None
None
None
None
 0.94A 3mdzA-6ekiA:
29.4		 3mdzA-6ekiA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDZ_A_EZLA264_1
(CARBONIC ANHYDRASE 7)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		7 / 11 HIS A 119
HIS A 136
LEU A 201
THR A 202
THR A 203
PRO A 205
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
ZN  A 301 (-4.4A)
None
None
None
 1.45A 3mdzA-6ekiA:
29.4		 3mdzA-6ekiA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ML5_A_AZMA264_1
(CARBONIC ANHYDRASE 7)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		10 / 11 GLN A 115
HIS A 117
HIS A 119
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
None
 0.17A 3ml5A-6ekiA:
29.9		 3ml5A-6ekiA:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MWS_B_017B201_2
(HIV-1 PROTEASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 12 ARG A 247
ILE A 152
GLY A 150
VAL A  63
ILE A  65
 None
 1.01A 3mwsB-6ekiA:
undetectable		 3mwsB-6ekiA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_C_478C200_2
(HIV-1 PROTEASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 11 ARG A 247
ILE A 152
GLY A 150
PRO A  62
VAL A  63
ILE A  65
 None
 1.17A 3oxvD-6ekiA:
undetectable		 3oxvD-6ekiA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SEL_X_DXCX75_0
(CYTOCHROME C7)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		4 / 8 ILE A 162
LEU A 187
PHE A 116
GLY A  84
 None
 0.85A 3selX-6ekiA:
undetectable		 3selX-6ekiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ1_X_DXCX75_0
(CYTOCHROME C7)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		4 / 6 ILE A 162
LEU A 187
PHE A 116
GLY A  84
 None
 0.85A 3sj1X-6ekiA:
undetectable		 3sj1X-6ekiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V2J_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		10 / 11 GLN A 115
HIS A 117
HIS A 119
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
None
 0.23A 3v2jA-6ekiA:
30.0		 3v2jA-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V2J_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 11 HIS A 119
HIS A 136
LEU A 201
THR A 202
THR A 203
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
ZN  A 301 (-4.4A)
None
None
 1.46A 3v2jA-6ekiA:
30.0		 3v2jA-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V2J_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 11 HIS A 119
VAL A 138
LEU A 201
THR A 202
THR A 203
 ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
None
 0.87A 3v2jA-6ekiA:
30.0		 3v2jA-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V2M_A_AZMA303_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		9 / 10 GLN A 115
HIS A 117
HIS A 119
HIS A 136
VAL A 138
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
ZN  A 301 (-4.4A)
None
None
 0.20A 3v2mA-6ekiA:
30.1		 3v2mA-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V2M_A_AZMA303_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 10 HIS A 119
HIS A 136
LEU A 201
THR A 202
THR A 203
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
ZN  A 301 (-4.4A)
None
None
 1.45A 3v2mA-6ekiA:
30.1		 3v2mA-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W6H_A_AZMA303_1
(CARBONIC ANHYDRASE 1)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		7 / 8 GLN A 115
HIS A 117
HIS A 119
HIS A 136
LEU A 201
THR A 202
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
ZN  A 301 (-4.4A)
None
 0.41A 3w6hA-6ekiA:
29.9		 3w6hA-6ekiA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W6H_B_AZMB303_1
(CARBONIC ANHYDRASE 1)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		8 / 9 GLN A 115
HIS A 117
HIS A 119
GLU A 123
HIS A 136
LEU A 201
THR A 202
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
ZN  A 301 (-3.2A)
None
ZN  A 301 (-4.4A)
None
 0.42A 3w6hB-6ekiA:
29.9		 3w6hB-6ekiA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		9 / 10 GLN A 115
HIS A 117
HIS A 119
HIS A 136
VAL A 138
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
ZN  A 301 (-4.4A)
None
None
 0.46A 3zncA-6ekiA:
26.1		 3zncA-6ekiA:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZNC_A_BZ1A500_1
(CARBONIC ANHYDRASE
IV)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 10 HIS A 119
HIS A 136
LEU A 201
THR A 202
THR A 203
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
ZN  A 301 (-4.4A)
None
None
 1.47A 3zncA-6ekiA:
26.1		 3zncA-6ekiA:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQ7_A_LEUA902_0
(LEUCINE--TRNA LIGASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		4 / 7 LEU A 201
GLU A 134
HIS A 136
HIS A 117
 None
None
ZN  A 301 (-3.2A)
ZN  A 301 (-3.3A)
 1.25A 4aq7A-6ekiA:
undetectable		 4aq7A-6ekiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		10 / 10 GLN A 115
HIS A 117
HIS A 119
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
None
 0.17A 4coqA-6ekiA:
37.1		 4coqA-6ekiA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 10 HIS A 119
HIS A 117
THR A 203
THR A 202
TRP A  33
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
None
ZN  A 301 (-4.4A)
None
 1.34A 4coqA-6ekiA:
37.1		 4coqA-6ekiA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COQ_A_SANA300_1
(CARBONATE
DEHYDRATASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 10 HIS A 119
HIS A 136
LEU A 201
THR A 202
THR A 203
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
ZN  A 301 (-4.4A)
None
None
 1.49A 4coqA-6ekiA:
37.1		 4coqA-6ekiA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COQ_B_SANB300_1
(CARBONATE
DEHYDRATASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		9 / 9 HIS A 117
HIS A 119
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
THR A 203
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
None
 0.20A 4coqB-6ekiA:
36.8		 4coqB-6ekiA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COQ_B_SANB300_1
(CARBONATE
DEHYDRATASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 9 HIS A 119
HIS A 117
THR A 203
THR A 202
TRP A  33
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
None
ZN  A 301 (-4.4A)
None
 1.32A 4coqB-6ekiA:
36.8		 4coqB-6ekiA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COQ_B_SANB300_1
(CARBONATE
DEHYDRATASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 9 HIS A 119
HIS A 136
LEU A 201
THR A 202
THR A 203
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
ZN  A 301 (-4.4A)
None
None
 1.46A 4coqB-6ekiA:
36.8		 4coqB-6ekiA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4COQ_B_SANB300_1
(CARBONATE
DEHYDRATASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 9 HIS A 119
VAL A 138
LEU A 201
THR A 202
THR A 203
 ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
None
 0.87A 4coqB-6ekiA:
36.8		 4coqB-6ekiA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		9 / 10 GLN A 115
VAL A 138
LEU A 146
VAL A 148
LEU A 201
THR A 202
THR A 203
VAL A 210
TRP A 212
 None
None
None
None
None
ZN  A 301 (-4.4A)
None
None
None
 0.44A 4e3hA-6ekiA:
29.9		 4e3hA-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0C_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 11 GLN A 115
HIS A 117
GLU A 134
VAL A 138
THR A 202
 None
ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
 1.26A 4g0cA-6ekiA:
29.9		 4g0cA-6ekiA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0C_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		10 / 11 GLN A 115
HIS A 117
HIS A 119
GLU A 123
HIS A 136
VAL A 138
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
ZN  A 301 (-3.2A)
None
None
ZN  A 301 (-4.4A)
None
None
 0.23A 4g0cA-6ekiA:
29.9		 4g0cA-6ekiA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0C_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 11 HIS A 119
GLU A 123
VAL A 148
LEU A 201
THR A 203
 ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
None
None
None
 0.93A 4g0cA-6ekiA:
29.9		 4g0cA-6ekiA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G7A_A_AZMA302_1
(CARBONATE
DEHYDRATASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		7 / 11 GLN A 115
HIS A 117
GLU A 134
HIS A 136
VAL A 138
VAL A 148
TRP A 212
 None
ZN  A 301 (-3.3A)
None
ZN  A 301 (-3.2A)
None
None
None
 1.40A 4g7aA-6ekiA:
34.5		 4g7aA-6ekiA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G7A_A_AZMA302_1
(CARBONATE
DEHYDRATASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		11 / 11 GLN A 115
HIS A 117
HIS A 119
GLU A 123
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
None
 0.19A 4g7aA-6ekiA:
34.5		 4g7aA-6ekiA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G7A_A_AZMA302_1
(CARBONATE
DEHYDRATASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 11 HIS A 119
GLU A 123
VAL A 138
LEU A 201
THR A 202
THR A 203
 ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
None
None
ZN  A 301 (-4.4A)
None
 0.95A 4g7aA-6ekiA:
34.5		 4g7aA-6ekiA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G7A_B_AZMB302_1
(CARBONATE
DEHYDRATASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		7 / 11 GLN A 115
HIS A 117
GLU A 134
HIS A 136
VAL A 138
VAL A 148
TRP A 212
 None
ZN  A 301 (-3.3A)
None
ZN  A 301 (-3.2A)
None
None
None
 1.41A 4g7aB-6ekiA:
34.3		 4g7aB-6ekiA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G7A_B_AZMB302_1
(CARBONATE
DEHYDRATASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		11 / 11 GLN A 115
HIS A 117
HIS A 119
GLU A 123
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
None
 0.20A 4g7aB-6ekiA:
34.3		 4g7aB-6ekiA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G7A_B_AZMB302_1
(CARBONATE
DEHYDRATASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 11 HIS A 119
GLU A 123
VAL A 138
LEU A 201
THR A 202
THR A 203
 ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
None
None
ZN  A 301 (-4.4A)
None
 0.95A 4g7aB-6ekiA:
34.3		 4g7aB-6ekiA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HC3_A_DXCA75_0
(PPCA)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		4 / 7 ILE A 162
LEU A 187
PHE A 116
GLY A  84
 None
 0.89A 4hc3A-6ekiA:
undetectable		 4hc3A-6ekiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K0S_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		10 / 11 GLN A 115
HIS A 117
HIS A 119
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
None
 0.21A 4k0sA-6ekiA:
30.1		 4k0sA-6ekiA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K0S_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 11 HIS A 119
HIS A 136
LEU A 201
THR A 202
THR A 203
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
ZN  A 301 (-4.4A)
None
None
 1.46A 4k0sA-6ekiA:
30.1		 4k0sA-6ekiA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K0S_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 11 HIS A 119
VAL A 138
LEU A 201
THR A 202
THR A 203
 ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
None
 0.89A 4k0sA-6ekiA:
30.1		 4k0sA-6ekiA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K0Z_A_MZMA308_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		11 / 12 GLN A 115
HIS A 117
HIS A 119
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
THR A 203
PRO A 205
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
None
None
 0.30A 4k0zA-6ekiA:
30.1		 4k0zA-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K0Z_A_MZMA308_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 12 HIS A 117
HIS A 119
VAL A 148
LEU A 201
THR A 203
PRO A 205
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
None
None
None
None
 1.11A 4k0zA-6ekiA:
30.1		 4k0zA-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K0Z_A_MZMA308_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 12 HIS A 119
HIS A 117
VAL A 138
LEU A 201
THR A 203
PRO A 205
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
None
None
None
None
 1.35A 4k0zA-6ekiA:
30.1		 4k0zA-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K0Z_A_MZMA308_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 12 HIS A 119
VAL A 138
LEU A 201
THR A 202
THR A 203
PRO A 205
 ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
None
None
 0.86A 4k0zA-6ekiA:
30.1		 4k0zA-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K13_A_ETSA304_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		11 / 12 GLN A 115
HIS A 117
HIS A 119
HIS A 136
VAL A 138
LEU A 146
VAL A 148
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
None
None
ZN  A 301 (-4.4A)
None
None
 0.27A 4k13A-6ekiA:
30.1		 4k13A-6ekiA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K13_A_ETSA304_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 12 HIS A 119
HIS A 136
LEU A 201
THR A 202
THR A 203
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
ZN  A 301 (-4.4A)
None
None
 1.44A 4k13A-6ekiA:
30.1		 4k13A-6ekiA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K13_A_ETSA304_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 12 HIS A 119
LEU A 146
VAL A 138
LEU A 201
THR A 202
THR A 203
 ZN  A 301 (-3.3A)
None
None
None
ZN  A 301 (-4.4A)
None
 1.11A 4k13A-6ekiA:
30.1		 4k13A-6ekiA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LU3_A_AZMA302_1
(CARBONIC ANHYDRASE
14)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 11 GLN A 115
HIS A 117
GLU A 134
HIS A 136
VAL A 138
TRP A 212
 None
ZN  A 301 (-3.3A)
None
ZN  A 301 (-3.2A)
None
None
 1.43A 4lu3A-6ekiA:
28.9		 4lu3A-6ekiA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LU3_A_AZMA302_1
(CARBONIC ANHYDRASE
14)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 11 GLN A 115
HIS A 117
GLU A 134
VAL A 138
THR A 202
 None
ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
 1.22A 4lu3A-6ekiA:
28.9		 4lu3A-6ekiA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LU3_A_AZMA302_1
(CARBONIC ANHYDRASE
14)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		10 / 11 GLN A 115
HIS A 117
HIS A 119
GLU A 123
HIS A 136
VAL A 138
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
ZN  A 301 (-3.2A)
None
None
ZN  A 301 (-4.4A)
None
None
 0.25A 4lu3A-6ekiA:
28.9		 4lu3A-6ekiA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LU3_A_AZMA302_1
(CARBONIC ANHYDRASE
14)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 11 HIS A 119
GLU A 123
VAL A 148
LEU A 201
THR A 203
 ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
None
None
None
 0.86A 4lu3A-6ekiA:
28.9		 4lu3A-6ekiA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		11 / 12 ASN A  90
GLN A 115
HIS A 117
HIS A 119
VAL A 138
VAL A 148
LEU A 201
THR A 202
THR A 203
PRO A 205
TRP A 212
 None
None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
None
None
None
ZN  A 301 (-4.4A)
None
None
None
 0.39A 4m2rA-6ekiA:
30.0		 4m2rA-6ekiA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 12 ASN A  90
HIS A 117
VAL A 148
THR A 202
PRO A 204
TRP A 212
 None
ZN  A 301 (-3.3A)
None
ZN  A 301 (-4.4A)
None
None
 1.32A 4m2rA-6ekiA:
30.0		 4m2rA-6ekiA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 12 HIS A 119
LEU A 201
THR A 202
THR A 203
PRO A 205
TRP A 212
 ZN  A 301 (-3.3A)
None
ZN  A 301 (-4.4A)
None
None
None
 1.38A 4m2rA-6ekiA:
30.0		 4m2rA-6ekiA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 12 HIS A 119
VAL A 138
LEU A 201
THR A 202
THR A 203
PRO A 205
 ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
None
None
 0.90A 4m2rA-6ekiA:
30.0		 4m2rA-6ekiA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2R_A_BZ1A302_2
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		4 / 4 HIS A  92
GLU A 123
HIS A 136
LEU A 146
 None
ZN  A 301 ( 4.7A)
ZN  A 301 (-3.2A)
None
 0.28A 4m2rA-6ekiA:
30.0		 4m2rA-6ekiA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2U_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 12 HIS A  92
HIS A 119
VAL A 138
LEU A 201
THR A 202
THR A 203
 None
ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
None
 1.14A 4m2uA-6ekiA:
30.0		 4m2uA-6ekiA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2U_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		11 / 12 TRP A  33
HIS A  92
GLN A 115
HIS A 117
HIS A 119
VAL A 138
VAL A 148
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
None
None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
None
None
None
ZN  A 301 (-4.4A)
None
None
 0.44A 4m2uA-6ekiA:
30.0		 4m2uA-6ekiA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2U_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		8 / 12 TRP A  44
HIS A 117
HIS A 119
VAL A 138
VAL A 148
LEU A 201
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
None
None
None
None
None
 1.39A 4m2uA-6ekiA:
30.0		 4m2uA-6ekiA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		8 / 12 GLN A 115
HIS A 117
HIS A 119
VAL A 138
GLY A 144
LEU A 201
THR A 202
THR A 203
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
None
None
None
ZN  A 301 (-4.4A)
None
 1.15A 4m2vA-6ekiA:
30.0		 4m2vA-6ekiA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		9 / 12 GLN A 115
HIS A 117
HIS A 119
VAL A 138
VAL A 148
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
None
None
None
ZN  A 301 (-4.4A)
None
None
 0.22A 4m2vA-6ekiA:
30.0		 4m2vA-6ekiA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 12 HIS A 119
VAL A 138
LEU A 201
THR A 202
THR A 203
 ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
None
 0.87A 4m2vA-6ekiA:
30.0		 4m2vA-6ekiA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2V_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 12 HIS A 119
VAL A 148
GLY A 144
LEU A 201
THR A 203
 ZN  A 301 (-3.3A)
None
None
None
None
 0.99A 4m2vA-6ekiA:
30.0		 4m2vA-6ekiA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2W_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		11 / 12 GLN A 115
HIS A 117
HIS A 119
HIS A 136
VAL A 138
LEU A 146
VAL A 148
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
None
None
ZN  A 301 (-4.4A)
None
None
 0.24A 4m2wA-6ekiA:
30.0		 4m2wA-6ekiA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2W_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 12 HIS A 119
HIS A 136
LEU A 201
THR A 202
THR A 203
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
ZN  A 301 (-4.4A)
None
None
 1.45A 4m2wA-6ekiA:
30.0		 4m2wA-6ekiA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2W_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 12 HIS A 119
LEU A 146
VAL A 138
LEU A 201
THR A 202
THR A 203
 ZN  A 301 (-3.3A)
None
None
None
ZN  A 301 (-4.4A)
None
 1.16A 4m2wA-6ekiA:
30.0		 4m2wA-6ekiA:
16.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N16_A_CHDA301_0
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 8 GLN A 115
HIS A 117
HIS A 119
HIS A 136
THR A 202
THR A 203
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
ZN  A 301 (-4.4A)
None
 0.25A 4n16A-6ekiA:
30.0		 4n16A-6ekiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PXX_A_CHDA302_0
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 9 GLN A 115
HIS A 117
HIS A 119
HIS A 136
THR A 202
THR A 203
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
ZN  A 301 (-4.4A)
None
 0.25A 4pxxA-6ekiA:
30.0		 4pxxA-6ekiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1Y_A_017A106_2
(ASPARTYL PROTEASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 12 ARG A 247
ILE A 152
GLY A 150
VAL A  63
ILE A  65
 None
 0.88A 4q1yB-6ekiA:
undetectable		 4q1yB-6ekiA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWL_A_ASCA303_0
(DIOSCORIN 5)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 10 HIS A 119
VAL A 138
VAL A 148
THR A 202
TRP A 212
 ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
None
 0.33A 4twlA-6ekiA:
31.2		 4twlA-6ekiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWL_B_ASCB304_0
(DIOSCORIN 5)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 10 HIS A 119
VAL A 138
VAL A 148
THR A 202
TRP A 212
 ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
None
 0.30A 4twlB-6ekiA:
31.6		 4twlB-6ekiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UOV_A_AZMA299_1
(CARBONATE
DEHYDRATASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		7 / 11 GLN A 115
HIS A 117
GLU A 134
HIS A 136
VAL A 138
VAL A 148
TRP A 212
 None
ZN  A 301 (-3.3A)
None
ZN  A 301 (-3.2A)
None
None
None
 1.44A 4uovA-6ekiA:
36.4		 4uovA-6ekiA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UOV_A_AZMA299_1
(CARBONATE
DEHYDRATASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 11 GLN A 115
HIS A 117
GLU A 134
VAL A 138
THR A 202
 None
ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
 1.21A 4uovA-6ekiA:
36.4		 4uovA-6ekiA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UOV_A_AZMA299_1
(CARBONATE
DEHYDRATASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		11 / 11 GLN A 115
HIS A 117
HIS A 119
GLU A 123
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
None
 0.24A 4uovA-6ekiA:
36.4		 4uovA-6ekiA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UOV_A_AZMA299_1
(CARBONATE
DEHYDRATASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 11 HIS A 119
GLU A 123
VAL A 138
LEU A 201
THR A 202
THR A 203
 ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
None
None
ZN  A 301 (-4.4A)
None
 0.96A 4uovA-6ekiA:
36.4		 4uovA-6ekiA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UOV_B_AZMB299_1
(CARBONATE
DEHYDRATASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		7 / 11 GLN A 115
HIS A 117
GLU A 134
HIS A 136
VAL A 138
VAL A 148
TRP A 212
 None
ZN  A 301 (-3.3A)
None
ZN  A 301 (-3.2A)
None
None
None
 1.43A 4uovB-6ekiA:
36.6		 4uovB-6ekiA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UOV_B_AZMB299_1
(CARBONATE
DEHYDRATASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 11 GLN A 115
HIS A 117
GLU A 134
VAL A 138
THR A 202
 None
ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
 1.18A 4uovB-6ekiA:
36.6		 4uovB-6ekiA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UOV_B_AZMB299_1
(CARBONATE
DEHYDRATASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		11 / 11 GLN A 115
HIS A 117
HIS A 119
GLU A 123
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
None
 0.21A 4uovB-6ekiA:
36.6		 4uovB-6ekiA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UOV_B_AZMB299_1
(CARBONATE
DEHYDRATASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 11 HIS A 119
GLU A 123
VAL A 138
LEU A 201
THR A 202
THR A 203
 ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
None
None
ZN  A 301 (-4.4A)
None
 0.95A 4uovB-6ekiA:
36.6		 4uovB-6ekiA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UOV_C_AZMC299_1
(CARBONATE
DEHYDRATASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		7 / 11 GLN A 115
HIS A 117
GLU A 134
HIS A 136
VAL A 138
VAL A 148
TRP A 212
 None
ZN  A 301 (-3.3A)
None
ZN  A 301 (-3.2A)
None
None
None
 1.45A 4uovC-6ekiA:
36.2		 4uovC-6ekiA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UOV_C_AZMC299_1
(CARBONATE
DEHYDRATASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 11 GLN A 115
HIS A 117
GLU A 134
VAL A 138
THR A 202
 None
ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
 1.21A 4uovC-6ekiA:
36.2		 4uovC-6ekiA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UOV_C_AZMC299_1
(CARBONATE
DEHYDRATASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		11 / 11 GLN A 115
HIS A 117
HIS A 119
GLU A 123
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
None
 0.24A 4uovC-6ekiA:
36.2		 4uovC-6ekiA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UOV_C_AZMC299_1
(CARBONATE
DEHYDRATASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 11 HIS A 119
GLU A 123
VAL A 138
LEU A 201
THR A 202
THR A 203
 ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
None
None
ZN  A 301 (-4.4A)
None
 0.96A 4uovC-6ekiA:
36.2		 4uovC-6ekiA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UOV_D_AZMD299_1
(CARBONATE
DEHYDRATASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		7 / 11 GLN A 115
HIS A 117
GLU A 134
HIS A 136
VAL A 138
VAL A 148
TRP A 212
 None
ZN  A 301 (-3.3A)
None
ZN  A 301 (-3.2A)
None
None
None
 1.43A 4uovD-6ekiA:
36.4		 4uovD-6ekiA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UOV_D_AZMD299_1
(CARBONATE
DEHYDRATASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 11 GLN A 115
HIS A 117
GLU A 134
VAL A 138
THR A 202
 None
ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
 1.21A 4uovD-6ekiA:
36.4		 4uovD-6ekiA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UOV_D_AZMD299_1
(CARBONATE
DEHYDRATASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		11 / 11 GLN A 115
HIS A 117
HIS A 119
GLU A 123
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
None
 0.23A 4uovD-6ekiA:
36.4		 4uovD-6ekiA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UOV_D_AZMD299_1
(CARBONATE
DEHYDRATASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 11 HIS A 119
GLU A 123
VAL A 138
LEU A 201
THR A 202
THR A 203
 ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
None
None
ZN  A 301 (-4.4A)
None
 0.96A 4uovD-6ekiA:
36.4		 4uovD-6ekiA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UOV_E_AZME299_1
(CARBONATE
DEHYDRATASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		7 / 11 GLN A 115
HIS A 117
GLU A 134
HIS A 136
VAL A 138
VAL A 148
TRP A 212
 None
ZN  A 301 (-3.3A)
None
ZN  A 301 (-3.2A)
None
None
None
 1.45A 4uovE-6ekiA:
36.4		 4uovE-6ekiA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UOV_E_AZME299_1
(CARBONATE
DEHYDRATASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 11 GLN A 115
HIS A 117
GLU A 134
VAL A 138
THR A 202
 None
ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
 1.20A 4uovE-6ekiA:
36.4		 4uovE-6ekiA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UOV_E_AZME299_1
(CARBONATE
DEHYDRATASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		11 / 11 GLN A 115
HIS A 117
HIS A 119
GLU A 123
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
None
 0.23A 4uovE-6ekiA:
36.4		 4uovE-6ekiA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UOV_E_AZME299_1
(CARBONATE
DEHYDRATASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 11 HIS A 119
GLU A 123
VAL A 138
LEU A 201
THR A 202
THR A 203
 ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
None
None
ZN  A 301 (-4.4A)
None
 0.96A 4uovE-6ekiA:
36.4		 4uovE-6ekiA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UOV_F_AZMF299_1
(CARBONATE
DEHYDRATASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		7 / 11 GLN A 115
HIS A 117
GLU A 134
HIS A 136
VAL A 138
VAL A 148
TRP A 212
 None
ZN  A 301 (-3.3A)
None
ZN  A 301 (-3.2A)
None
None
None
 1.43A 4uovF-6ekiA:
36.6		 4uovF-6ekiA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UOV_F_AZMF299_1
(CARBONATE
DEHYDRATASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 11 GLN A 115
HIS A 117
GLU A 134
VAL A 138
THR A 202
 None
ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
 1.19A 4uovF-6ekiA:
36.6		 4uovF-6ekiA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UOV_F_AZMF299_1
(CARBONATE
DEHYDRATASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		11 / 11 GLN A 115
HIS A 117
HIS A 119
GLU A 123
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
None
 0.22A 4uovF-6ekiA:
36.6		 4uovF-6ekiA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UOV_F_AZMF299_1
(CARBONATE
DEHYDRATASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 11 HIS A 119
GLU A 123
VAL A 138
LEU A 201
THR A 202
THR A 203
 ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
None
None
ZN  A 301 (-4.4A)
None
 0.95A 4uovF-6ekiA:
36.6		 4uovF-6ekiA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5S_A_AZMA302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 11 GLN A 115
GLU A 134
HIS A 136
VAL A 138
VAL A 148
TRP A 212
 None
None
ZN  A 301 (-3.2A)
None
None
None
 1.42A 4x5sA-6ekiA:
35.4		 4x5sA-6ekiA:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5S_A_AZMA302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		11 / 11 GLN A 115
HIS A 117
HIS A 119
GLU A 123
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
None
 0.23A 4x5sA-6ekiA:
35.4		 4x5sA-6ekiA:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5S_A_AZMA302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 11 HIS A 119
GLU A 123
VAL A 138
LEU A 201
THR A 202
THR A 203
 ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
None
None
ZN  A 301 (-4.4A)
None
 0.99A 4x5sA-6ekiA:
35.4		 4x5sA-6ekiA:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5S_A_AZMA302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 11 HIS A 119
HIS A 136
LEU A 201
THR A 202
THR A 203
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
ZN  A 301 (-4.4A)
None
None
 1.50A 4x5sA-6ekiA:
35.4		 4x5sA-6ekiA:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5S_B_AZMB302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 11 GLN A 115
GLU A 134
HIS A 136
VAL A 138
VAL A 148
TRP A 212
 None
None
ZN  A 301 (-3.2A)
None
None
None
 1.42A 4x5sB-6ekiA:
35.3		 4x5sB-6ekiA:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5S_B_AZMB302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		11 / 11 GLN A 115
HIS A 117
HIS A 119
GLU A 123
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
None
 0.23A 4x5sB-6ekiA:
35.3		 4x5sB-6ekiA:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5S_B_AZMB302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 11 HIS A 119
GLU A 123
VAL A 148
LEU A 201
THR A 203
 ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
None
None
None
 0.95A 4x5sB-6ekiA:
35.3		 4x5sB-6ekiA:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5S_B_AZMB302_1
(CARBONIC ANHYDRASE
(CARBONATE
DEHYDRATASE))		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 11 HIS A 119
VAL A 138
LEU A 201
THR A 202
THR A 203
 ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
None
 0.89A 4x5sB-6ekiA:
35.3		 4x5sB-6ekiA:
24.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_A_AZMA402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		7 / 12 GLN A 115
HIS A 117
GLU A 134
HIS A 136
VAL A 138
VAL A 148
TRP A 212
 None
ZN  A 301 (-3.3A)
None
ZN  A 301 (-3.2A)
None
None
None
 1.36A 4xiwA-6ekiA:
28.9
4xiwH-6ekiA:
28.7		 4xiwA-6ekiA:
16.90
4xiwH-6ekiA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_A_AZMA402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		11 / 12 GLN A 115
HIS A 117
HIS A 119
GLU A 123
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
None
 0.26A 4xiwA-6ekiA:
28.9
4xiwH-6ekiA:
28.7		 4xiwA-6ekiA:
16.90
4xiwH-6ekiA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_A_AZMA402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 12 HIS A 119
GLU A 123
VAL A 138
LEU A 201
THR A 202
THR A 203
 ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
None
None
ZN  A 301 (-4.4A)
None
 0.99A 4xiwA-6ekiA:
28.9
4xiwH-6ekiA:
28.7		 4xiwA-6ekiA:
16.90
4xiwH-6ekiA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_B_AZMB402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 12 GLN A 115
HIS A 117
GLU A 134
HIS A 136
VAL A 138
TRP A 212
 None
ZN  A 301 (-3.3A)
None
ZN  A 301 (-3.2A)
None
None
 1.44A 4xiwB-6ekiA:
28.8
4xiwE-6ekiA:
29.0		 4xiwB-6ekiA:
16.90
4xiwE-6ekiA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_B_AZMB402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 12 GLN A 115
HIS A 117
GLU A 134
VAL A 138
THR A 202
 None
ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
 1.18A 4xiwB-6ekiA:
28.8
4xiwE-6ekiA:
29.0		 4xiwB-6ekiA:
16.90
4xiwE-6ekiA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_B_AZMB402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		10 / 12 GLN A 115
HIS A 117
HIS A 119
GLU A 123
HIS A 136
VAL A 138
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
ZN  A 301 (-3.2A)
None
None
ZN  A 301 (-4.4A)
None
None
 0.27A 4xiwB-6ekiA:
28.8
4xiwE-6ekiA:
29.0		 4xiwB-6ekiA:
16.90
4xiwE-6ekiA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_B_AZMB402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 12 HIS A 119
GLU A 123
VAL A 148
LEU A 201
THR A 203
 ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
None
None
None
 0.93A 4xiwB-6ekiA:
28.8
4xiwE-6ekiA:
29.0		 4xiwB-6ekiA:
16.90
4xiwE-6ekiA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_C_AZMC402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		7 / 11 GLN A 115
HIS A 117
GLU A 134
HIS A 136
VAL A 138
VAL A 148
TRP A 212
 None
ZN  A 301 (-3.3A)
None
ZN  A 301 (-3.2A)
None
None
None
 1.29A 4xiwC-6ekiA:
28.6		 4xiwC-6ekiA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_C_AZMC402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		11 / 11 GLN A 115
HIS A 117
HIS A 119
GLU A 123
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
None
 0.29A 4xiwC-6ekiA:
28.6		 4xiwC-6ekiA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_C_AZMC402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 11 HIS A 119
GLU A 123
VAL A 138
LEU A 201
THR A 202
THR A 203
 ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
None
None
ZN  A 301 (-4.4A)
None
 1.05A 4xiwC-6ekiA:
28.6		 4xiwC-6ekiA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_D_AZMD402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		7 / 11 GLN A 115
HIS A 117
GLU A 134
HIS A 136
VAL A 138
VAL A 148
TRP A 212
 None
ZN  A 301 (-3.3A)
None
ZN  A 301 (-3.2A)
None
None
None
 1.34A 4xiwD-6ekiA:
29.1		 4xiwD-6ekiA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_D_AZMD402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		11 / 11 GLN A 115
HIS A 117
HIS A 119
GLU A 123
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
None
 0.21A 4xiwD-6ekiA:
29.1		 4xiwD-6ekiA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_D_AZMD402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 11 HIS A 119
GLU A 123
VAL A 138
LEU A 201
THR A 202
THR A 203
 ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
None
None
ZN  A 301 (-4.4A)
None
 0.99A 4xiwD-6ekiA:
29.1		 4xiwD-6ekiA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_E_AZME402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		7 / 11 GLN A 115
HIS A 117
GLU A 134
HIS A 136
VAL A 138
VAL A 148
TRP A 212
 None
ZN  A 301 (-3.3A)
None
ZN  A 301 (-3.2A)
None
None
None
 1.37A 4xiwE-6ekiA:
29.0		 4xiwE-6ekiA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_E_AZME402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		11 / 11 GLN A 115
HIS A 117
HIS A 119
GLU A 123
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
None
 0.22A 4xiwE-6ekiA:
29.0		 4xiwE-6ekiA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_E_AZME402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 11 HIS A 119
GLU A 123
VAL A 138
LEU A 201
THR A 202
THR A 203
 ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
None
None
ZN  A 301 (-4.4A)
None
 0.97A 4xiwE-6ekiA:
29.0		 4xiwE-6ekiA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_E_AZME402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 11 HIS A 119
HIS A 136
LEU A 201
THR A 202
THR A 203
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
ZN  A 301 (-4.4A)
None
None
 1.49A 4xiwE-6ekiA:
29.0		 4xiwE-6ekiA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_F_AZMF402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		7 / 11 GLN A 115
HIS A 117
GLU A 134
HIS A 136
VAL A 138
VAL A 148
TRP A 212
 None
ZN  A 301 (-3.3A)
None
ZN  A 301 (-3.2A)
None
None
None
 1.42A 4xiwF-6ekiA:
28.8		 4xiwF-6ekiA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_F_AZMF402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		11 / 11 GLN A 115
HIS A 117
HIS A 119
GLU A 123
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
None
 0.21A 4xiwF-6ekiA:
28.8		 4xiwF-6ekiA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_F_AZMF402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 11 HIS A 119
GLU A 123
VAL A 148
LEU A 201
THR A 203
 ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
None
None
None
 0.91A 4xiwF-6ekiA:
28.8		 4xiwF-6ekiA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_F_AZMF402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 11 HIS A 119
VAL A 138
LEU A 201
THR A 202
THR A 203
 ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
None
 0.91A 4xiwF-6ekiA:
28.8		 4xiwF-6ekiA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_G_AZMG402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 12 GLN A 115
GLU A 134
VAL A 138
LEU A 146
VAL A 148
TRP A 212
 None
 1.31A 4xiwG-6ekiA:
28.8		 4xiwG-6ekiA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_G_AZMG402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		12 / 12 GLN A 115
HIS A 117
HIS A 119
GLU A 123
HIS A 136
VAL A 138
LEU A 146
VAL A 148
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
ZN  A 301 (-3.2A)
None
None
None
None
ZN  A 301 (-4.4A)
None
None
 0.37A 4xiwG-6ekiA:
28.8		 4xiwG-6ekiA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_G_AZMG402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		7 / 12 HIS A 119
GLU A 123
LEU A 146
VAL A 138
LEU A 201
THR A 202
THR A 203
 ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
None
None
None
ZN  A 301 (-4.4A)
None
 1.29A 4xiwG-6ekiA:
28.8		 4xiwG-6ekiA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_H_AZMH402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		7 / 11 GLN A 115
HIS A 117
GLU A 134
HIS A 136
VAL A 138
VAL A 148
TRP A 212
 None
ZN  A 301 (-3.3A)
None
ZN  A 301 (-3.2A)
None
None
None
 1.36A 4xiwH-6ekiA:
28.7		 4xiwH-6ekiA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_H_AZMH402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		11 / 11 GLN A 115
HIS A 117
HIS A 119
GLU A 123
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
None
 0.25A 4xiwH-6ekiA:
28.7		 4xiwH-6ekiA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XIW_H_AZMH402_1
(CARBONIC ANHYDRASE,
ALPHA TYPE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 11 HIS A 119
GLU A 123
VAL A 138
LEU A 201
THR A 202
THR A 203
 ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
None
None
ZN  A 301 (-4.4A)
None
 1.00A 4xiwH-6ekiA:
28.7		 4xiwH-6ekiA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_A_AZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		8 / 11 HIS A 117
HIS A 119
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
 0.36A 4ygfA-6ekiA:
30.5		 4ygfA-6ekiA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_A_AZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		7 / 11 LYS A  95
HIS A 117
HIS A 119
HIS A 136
LEU A 201
THR A 202
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
ZN  A 301 (-4.4A)
None
 0.62A 4ygfA-6ekiA:
30.5		 4ygfA-6ekiA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_B_AZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		9 / 11 HIS A 117
HIS A 119
GLU A 123
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
 0.33A 4ygfB-6ekiA:
30.3		 4ygfB-6ekiA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_B_AZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 11 HIS A 119
GLU A 123
VAL A 138
LEU A 201
THR A 202
 ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
None
None
ZN  A 301 (-4.4A)
 0.68A 4ygfB-6ekiA:
30.3		 4ygfB-6ekiA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_B_AZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 11 HIS A 119
HIS A 117
VAL A 138
LEU A 201
THR A 202
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
 1.41A 4ygfB-6ekiA:
30.3		 4ygfB-6ekiA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_C_AZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		9 / 11 LYS A  95
HIS A 117
HIS A 119
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
 0.52A 4ygfC-6ekiA:
22.4		 4ygfC-6ekiA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_D_AZMD303_1
(ALPHA-CARBONIC
ANHYDRASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		9 / 11 HIS A 117
HIS A 119
GLU A 123
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
 0.25A 4ygfD-6ekiA:
14.4		 4ygfD-6ekiA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_D_AZMD303_1
(ALPHA-CARBONIC
ANHYDRASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 11 HIS A 119
GLU A 123
HIS A 136
VAL A 138
LEU A 201
THR A 202
 ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
ZN  A 301 (-3.2A)
None
None
ZN  A 301 (-4.4A)
 1.02A 4ygfD-6ekiA:
14.4		 4ygfD-6ekiA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_D_AZMD303_1
(ALPHA-CARBONIC
ANHYDRASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 11 HIS A 136
HIS A 119
VAL A 148
LEU A 201
THR A 202
 ZN  A 301 (-3.2A)
ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
 1.40A 4ygfD-6ekiA:
14.4		 4ygfD-6ekiA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_E_AZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		9 / 12 HIS A 117
HIS A 119
GLU A 123
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
 0.32A 4ygfE-6ekiA:
30.7		 4ygfE-6ekiA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_E_AZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 12 HIS A 119
GLU A 123
VAL A 138
LEU A 201
THR A 202
 ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
None
None
ZN  A 301 (-4.4A)
 0.74A 4ygfE-6ekiA:
30.7		 4ygfE-6ekiA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_E_AZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 12 LYS A  95
HIS A 117
HIS A 119
GLU A 123
HIS A 136
THR A 202
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
ZN  A 301 (-3.2A)
ZN  A 301 (-4.4A)
 0.61A 4ygfE-6ekiA:
30.7		 4ygfE-6ekiA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_F_AZMF303_1
(ALPHA-CARBONIC
ANHYDRASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		8 / 9 HIS A 117
HIS A 119
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
 0.28A 4ygfF-6ekiA:
30.2		 4ygfF-6ekiA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_G_AZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		8 / 12 HIS A 117
HIS A 119
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
 0.25A 4ygfG-6ekiA:
6.9		 4ygfG-6ekiA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_G_AZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 12 HIS A 119
HIS A 136
VAL A 138
LEU A 201
THR A 202
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
ZN  A 301 (-4.4A)
 1.02A 4ygfG-6ekiA:
6.9		 4ygfG-6ekiA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_G_AZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 12 LYS A  95
HIS A 117
HIS A 119
HIS A 136
LEU A 201
THR A 202
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
ZN  A 301 (-4.4A)
 0.64A 4ygfG-6ekiA:
6.9		 4ygfG-6ekiA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_H_AZMH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		8 / 9 HIS A 117
HIS A 119
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
 0.28A 4ygfH-6ekiA:
30.2		 4ygfH-6ekiA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YGF_H_AZMH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 9 HIS A 119
HIS A 117
VAL A 138
LEU A 201
THR A 202
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
 1.37A 4ygfH-6ekiA:
30.2		 4ygfH-6ekiA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_A_MZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 12 HIS A 117
HIS A 119
VAL A 138
LEU A 201
THR A 202
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
 1.14A 4yhaA-6ekiA:
30.5		 4yhaA-6ekiA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_A_MZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		9 / 12 LYS A  95
HIS A 117
HIS A 119
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
 0.61A 4yhaA-6ekiA:
30.5		 4yhaA-6ekiA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_B_MZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		7 / 10 HIS A 117
HIS A 119
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
 0.46A 4yhaB-6ekiA:
29.6		 4yhaB-6ekiA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_B_MZMB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 10 HIS A 119
HIS A 136
VAL A 138
LEU A 201
THR A 202
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
ZN  A 301 (-4.4A)
 1.09A 4yhaB-6ekiA:
29.6		 4yhaB-6ekiA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_C_MZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		8 / 11 HIS A 117
HIS A 119
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
 0.35A 4yhaC-6ekiA:
30.6		 4yhaC-6ekiA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_C_MZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 11 HIS A 117
HIS A 119
VAL A 138
LEU A 201
THR A 203
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
None
None
None
 1.49A 4yhaC-6ekiA:
30.6		 4yhaC-6ekiA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_C_MZMC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		8 / 11 LYS A  95
HIS A 117
HIS A 119
HIS A 136
VAL A 148
LEU A 201
THR A 202
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
ZN  A 301 (-4.4A)
None
 0.60A 4yhaC-6ekiA:
30.6		 4yhaC-6ekiA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_D_MZMD302_1
(ALPHA-CARBONIC
ANHYDRASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		8 / 11 HIS A 117
HIS A 119
GLU A 123
HIS A 136
VAL A 138
LEU A 201
THR A 202
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
ZN  A 301 (-3.2A)
None
None
ZN  A 301 (-4.4A)
None
 0.39A 4yhaD-6ekiA:
29.5		 4yhaD-6ekiA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_D_MZMD302_1
(ALPHA-CARBONIC
ANHYDRASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		8 / 11 LYS A  95
HIS A 117
HIS A 119
GLU A 123
HIS A 136
LEU A 201
THR A 202
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
ZN  A 301 (-3.2A)
None
ZN  A 301 (-4.4A)
None
 0.56A 4yhaD-6ekiA:
29.5		 4yhaD-6ekiA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_E_MZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		9 / 12 HIS A 117
HIS A 119
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
PRO A 205
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
None
 0.40A 4yhaE-6ekiA:
30.7		 4yhaE-6ekiA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_E_MZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 12 HIS A 117
HIS A 136
LEU A 201
THR A 202
PRO A 205
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
ZN  A 301 (-4.4A)
None
None
 1.50A 4yhaE-6ekiA:
30.7		 4yhaE-6ekiA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_E_MZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		9 / 12 LYS A  95
HIS A 117
HIS A 119
HIS A 136
VAL A 138
LEU A 201
THR A 202
PRO A 205
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
ZN  A 301 (-4.4A)
None
None
 0.59A 4yhaE-6ekiA:
30.7		 4yhaE-6ekiA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_E_MZME303_1
(ALPHA-CARBONIC
ANHYDRASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 12 LYS A  95
HIS A 117
HIS A 136
LEU A 201
PRO A 204
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
None
 1.47A 4yhaE-6ekiA:
30.7		 4yhaE-6ekiA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_F_MZMF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		7 / 10 HIS A 117
HIS A 119
HIS A 136
VAL A 138
LEU A 201
THR A 202
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
ZN  A 301 (-4.4A)
None
 0.60A 4yhaF-6ekiA:
27.9		 4yhaF-6ekiA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_G_MZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		8 / 12 HIS A 117
HIS A 119
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
 0.33A 4yhaG-6ekiA:
29.9		 4yhaG-6ekiA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_G_MZMG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 12 LYS A  95
HIS A 117
HIS A 119
HIS A 136
LEU A 201
THR A 202
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
ZN  A 301 (-4.4A)
 0.63A 4yhaG-6ekiA:
29.9		 4yhaG-6ekiA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_H_MZMH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		8 / 10 HIS A 117
HIS A 119
GLU A 123
HIS A 136
VAL A 138
LEU A 201
THR A 202
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
ZN  A 301 (-3.2A)
None
None
ZN  A 301 (-4.4A)
None
 0.39A 4yhaH-6ekiA:
30.0		 4yhaH-6ekiA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C8I_A_MZMA302_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 12 GLN A 115
HIS A 117
GLU A 134
VAL A 138
VAL A 148
TRP A 212
 None
ZN  A 301 (-3.3A)
None
None
None
None
 1.28A 5c8iA-6ekiA:
30.0		 5c8iA-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C8I_A_MZMA302_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		11 / 12 GLN A 115
HIS A 117
HIS A 119
GLU A 123
VAL A 138
VAL A 148
LEU A 201
THR A 202
THR A 203
PRO A 205
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
None
None
None
ZN  A 301 (-4.4A)
None
None
None
 0.32A 5c8iA-6ekiA:
30.0		 5c8iA-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C8I_A_MZMA302_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		7 / 12 HIS A 117
HIS A 119
GLU A 123
VAL A 148
LEU A 201
THR A 203
PRO A 205
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
None
None
None
None
 1.08A 5c8iA-6ekiA:
30.0		 5c8iA-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C8I_A_MZMA302_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		7 / 12 HIS A 119
GLU A 123
VAL A 138
LEU A 201
THR A 202
THR A 203
PRO A 205
 ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
None
None
ZN  A 301 (-4.4A)
None
None
 0.94A 5c8iA-6ekiA:
30.0		 5c8iA-6ekiA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ERYA404_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 12 GLY A 199
ASN A  59
GLU A  70
ALA A 246
ILE A  65
 None
 1.00A 5ih0A-6ekiA:
undetectable		 5ih0A-6ekiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN8_A_AZMA701_1
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		10 / 10 GLN A 115
HIS A 117
HIS A 119
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
None
 0.36A 5jn8A-6ekiA:
26.6		 5jn8A-6ekiA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN8_A_AZMA701_1
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 10 HIS A 119
HIS A 117
THR A 203
THR A 202
TRP A  33
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
None
ZN  A 301 (-4.4A)
None
 1.39A 5jn8A-6ekiA:
26.6		 5jn8A-6ekiA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN8_A_AZMA701_1
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 10 HIS A 119
HIS A 117
VAL A 138
LEU A 201
THR A 202
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
 1.37A 5jn8A-6ekiA:
26.6		 5jn8A-6ekiA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN8_A_AZMA701_1
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 10 HIS A 119
VAL A 138
LEU A 201
THR A 202
THR A 203
 ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
None
 0.90A 5jn8A-6ekiA:
26.6		 5jn8A-6ekiA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN8_B_AZMB701_1
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		7 / 11 GLN A 115
HIS A 117
GLU A 134
HIS A 136
VAL A 138
VAL A 148
TRP A 212
 None
ZN  A 301 (-3.3A)
None
ZN  A 301 (-3.2A)
None
None
None
 1.47A 5jn8B-6ekiA:
27.0		 5jn8B-6ekiA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN8_B_AZMB701_1
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		11 / 11 GLN A 115
HIS A 117
HIS A 119
GLU A 123
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
None
 0.37A 5jn8B-6ekiA:
27.0		 5jn8B-6ekiA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN8_B_AZMB701_1
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 11 HIS A 119
GLU A 123
VAL A 138
LEU A 201
THR A 202
THR A 203
 ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
None
None
ZN  A 301 (-4.4A)
None
 0.98A 5jn8B-6ekiA:
27.0		 5jn8B-6ekiA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN8_C_AZMC701_1
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		9 / 9 GLN A 115
HIS A 117
HIS A 119
HIS A 136
VAL A 138
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
ZN  A 301 (-4.4A)
None
None
 0.37A 5jn8C-6ekiA:
26.5		 5jn8C-6ekiA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN8_D_AZMD701_1
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 10 GLN A 115
HIS A 117
GLU A 134
VAL A 138
THR A 202
 None
ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
 1.26A 5jn8D-6ekiA:
26.4		 5jn8D-6ekiA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN8_D_AZMD701_1
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		10 / 10 GLN A 115
HIS A 117
HIS A 119
GLU A 123
HIS A 136
VAL A 138
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
ZN  A 301 (-3.2A)
None
None
ZN  A 301 (-4.4A)
None
None
 0.32A 5jn8D-6ekiA:
26.4		 5jn8D-6ekiA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN8_D_AZMD701_1
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 10 HIS A 119
GLU A 123
VAL A 148
LEU A 201
THR A 203
 ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
None
None
None
 1.00A 5jn8D-6ekiA:
26.4		 5jn8D-6ekiA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN8_D_AZMD701_1
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 10 HIS A 136
HIS A 119
VAL A 148
LEU A 201
THR A 203
 ZN  A 301 (-3.2A)
ZN  A 301 (-3.3A)
None
None
None
 1.46A 5jn8D-6ekiA:
26.4		 5jn8D-6ekiA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		10 / 10 GLN A 115
HIS A 117
HIS A 119
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
None
 0.33A 5jn9A-6ekiA:
26.7		 5jn9A-6ekiA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 10 GLN A 115
HIS A 117
HIS A 136
LEU A 146
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
 1.45A 5jn9A-6ekiA:
26.7		 5jn9A-6ekiA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 10 HIS A 119
HIS A 117
THR A 203
THR A 202
TRP A  33
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
None
ZN  A 301 (-4.4A)
None
 1.38A 5jn9A-6ekiA:
26.7		 5jn9A-6ekiA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 10 HIS A 119
HIS A 117
VAL A 138
LEU A 201
THR A 202
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
 1.38A 5jn9A-6ekiA:
26.7		 5jn9A-6ekiA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_A_EZLA302_1
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 10 HIS A 119
VAL A 138
LEU A 201
THR A 202
THR A 203
 ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
None
 0.88A 5jn9A-6ekiA:
26.7		 5jn9A-6ekiA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		10 / 10 GLN A 115
HIS A 117
HIS A 119
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
None
 0.35A 5jn9B-6ekiA:
27.2		 5jn9B-6ekiA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 10 HIS A 119
HIS A 117
VAL A 138
LEU A 201
THR A 202
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
 1.42A 5jn9B-6ekiA:
27.2		 5jn9B-6ekiA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 10 HIS A 119
VAL A 138
LEU A 201
THR A 202
THR A 203
 ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
None
 0.94A 5jn9B-6ekiA:
27.2		 5jn9B-6ekiA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_B_EZLB302_1
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 10 HIS A 136
HIS A 119
VAL A 148
LEU A 201
THR A 203
 ZN  A 301 (-3.2A)
ZN  A 301 (-3.3A)
None
None
None
 1.46A 5jn9B-6ekiA:
27.2		 5jn9B-6ekiA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		9 / 9 GLN A 115
HIS A 117
HIS A 119
HIS A 136
VAL A 138
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
ZN  A 301 (-4.4A)
None
None
 0.30A 5jn9C-6ekiA:
26.5		 5jn9C-6ekiA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 9 GLN A 115
HIS A 117
HIS A 136
LEU A 146
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
 1.44A 5jn9C-6ekiA:
26.5		 5jn9C-6ekiA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 9 HIS A 119
HIS A 117
THR A 203
THR A 202
TRP A  33
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
None
ZN  A 301 (-4.4A)
None
 1.35A 5jn9C-6ekiA:
26.5		 5jn9C-6ekiA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_C_EZLC302_1
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 9 HIS A 119
HIS A 136
LEU A 201
THR A 202
THR A 203
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
ZN  A 301 (-4.4A)
None
None
 1.48A 5jn9C-6ekiA:
26.5		 5jn9C-6ekiA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		10 / 10 GLN A 115
HIS A 117
HIS A 119
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
None
 0.31A 5jn9D-6ekiA:
26.4		 5jn9D-6ekiA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 10 HIS A 119
HIS A 117
THR A 203
THR A 202
TRP A  33
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
None
ZN  A 301 (-4.4A)
None
 1.34A 5jn9D-6ekiA:
26.4		 5jn9D-6ekiA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 10 HIS A 119
HIS A 117
VAL A 138
LEU A 201
THR A 202
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
 1.34A 5jn9D-6ekiA:
26.4		 5jn9D-6ekiA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JN9_D_EZLD302_1
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 10 HIS A 119
VAL A 138
LEU A 201
THR A 202
THR A 203
 ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
None
 0.86A 5jn9D-6ekiA:
26.4		 5jn9D-6ekiA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNA_A_TORA302_1
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		11 / 12 ASN A  90
GLN A 115
HIS A 117
HIS A 119
GLU A 123
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
THR A 203
 None
None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
 0.52A 5jnaA-6ekiA:
26.6		 5jnaA-6ekiA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNA_A_TORA302_1
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 12 HIS A 119
GLU A 123
VAL A 148
LEU A 201
THR A 203
 ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
None
None
None
 1.01A 5jnaA-6ekiA:
26.6		 5jnaA-6ekiA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNA_A_TORA302_1
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 12 HIS A 119
VAL A 138
LEU A 201
THR A 202
THR A 203
 ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
None
 0.92A 5jnaA-6ekiA:
26.6		 5jnaA-6ekiA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNA_B_TORB302_1
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		11 / 12 ASN A  90
GLN A 115
HIS A 117
HIS A 119
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
None
 0.52A 5jnaB-6ekiA:
27.0		 5jnaB-6ekiA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNA_B_TORB302_1
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 12 HIS A 119
HIS A 117
VAL A 138
LEU A 201
THR A 202
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
 1.34A 5jnaB-6ekiA:
27.0		 5jnaB-6ekiA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNA_B_TORB302_1
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 12 HIS A 119
VAL A 138
LEU A 201
THR A 202
THR A 203
 ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
None
 0.93A 5jnaB-6ekiA:
27.0		 5jnaB-6ekiA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNA_C_TORC302_1
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		10 / 11 ASN A  90
GLN A 115
HIS A 117
HIS A 119
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
THR A 203
 None
None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
 0.51A 5jnaC-6ekiA:
26.3		 5jnaC-6ekiA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNA_C_TORC302_1
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 11 HIS A 119
VAL A 138
LEU A 201
THR A 202
THR A 203
 ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
None
 0.92A 5jnaC-6ekiA:
26.3		 5jnaC-6ekiA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNA_D_TORD302_1
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		11 / 12 ASN A  90
GLN A 115
HIS A 117
HIS A 119
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
None
 0.50A 5jnaD-6ekiA:
26.3		 5jnaD-6ekiA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNA_D_TORD302_1
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 12 HIS A 119
VAL A 138
LEU A 201
THR A 202
THR A 203
 ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
None
 0.88A 5jnaD-6ekiA:
26.3		 5jnaD-6ekiA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		7 / 11 GLN A 115
HIS A 117
GLU A 134
HIS A 136
VAL A 138
VAL A 148
TRP A 212
 None
ZN  A 301 (-3.3A)
None
ZN  A 301 (-3.2A)
None
None
None
 1.48A 5jncA-6ekiA:
26.6		 5jncA-6ekiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 11 GLN A 115
HIS A 117
GLU A 134
VAL A 138
THR A 202
 None
ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
 1.29A 5jncA-6ekiA:
26.6		 5jncA-6ekiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		11 / 11 GLN A 115
HIS A 117
HIS A 119
GLU A 123
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
None
 0.37A 5jncA-6ekiA:
26.6		 5jncA-6ekiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_6LHA302_0
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 11 HIS A 119
GLU A 123
VAL A 138
LEU A 201
THR A 202
THR A 203
 ZN  A 301 (-3.3A)
ZN  A 301 ( 4.7A)
None
None
ZN  A 301 (-4.4A)
None
 1.00A 5jncA-6ekiA:
26.6		 5jncA-6ekiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		10 / 10 GLN A 115
HIS A 117
HIS A 119
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
None
 0.32A 5jncB-6ekiA:
27.1		 5jncB-6ekiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 10 HIS A 119
HIS A 117
VAL A 138
LEU A 201
THR A 202
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
 1.36A 5jncB-6ekiA:
27.1		 5jncB-6ekiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 10 HIS A 119
VAL A 138
LEU A 201
THR A 202
THR A 203
 ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
None
 0.94A 5jncB-6ekiA:
27.1		 5jncB-6ekiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_B_6LHB302_0
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 10 HIS A 136
HIS A 119
VAL A 148
LEU A 201
THR A 203
 ZN  A 301 (-3.2A)
ZN  A 301 (-3.3A)
None
None
None
 1.44A 5jncB-6ekiA:
27.1		 5jncB-6ekiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		9 / 9 GLN A 115
HIS A 117
HIS A 119
HIS A 136
VAL A 138
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
ZN  A 301 (-4.4A)
None
None
 0.32A 5jncC-6ekiA:
26.5		 5jncC-6ekiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_C_6LHC302_0
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 9 HIS A 119
HIS A 117
THR A 203
THR A 202
TRP A  33
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
None
ZN  A 301 (-4.4A)
None
 1.39A 5jncC-6ekiA:
26.5		 5jncC-6ekiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_D_6LHD302_0
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		9 / 9 GLN A 115
HIS A 117
HIS A 119
HIS A 136
VAL A 138
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
ZN  A 301 (-4.4A)
None
None
 0.31A 5jncD-6ekiA:
26.4		 5jncD-6ekiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_D_6LHD302_0
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 9 HIS A 119
HIS A 117
THR A 203
THR A 202
TRP A  33
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
None
ZN  A 301 (-4.4A)
None
 1.37A 5jncD-6ekiA:
26.4		 5jncD-6ekiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQY_B_017B101_1
(PROTEASE E35D-DRV)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 12 ARG A 247
ILE A 152
GLY A 150
VAL A  63
ILE A  65
 None
 0.84A 5kqyA-6ekiA:
undetectable		 5kqyA-6ekiA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR1_B_017B101_1
(PROTEASE PR5-DRV)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 10 ARG A 247
ILE A 152
GLY A 150
VAL A  63
ILE A  65
 None
 0.99A 5kr1A-6ekiA:
undetectable		 5kr1A-6ekiA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KU6_A_MZMA301_1
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		10 / 10 GLN A 115
HIS A 117
HIS A 119
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
None
 0.36A 5ku6A-6ekiA:
26.6		 5ku6A-6ekiA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KU6_A_MZMA301_1
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 10 HIS A 119
HIS A 117
THR A 203
THR A 202
TRP A  33
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
None
ZN  A 301 (-4.4A)
None
 1.37A 5ku6A-6ekiA:
26.6		 5ku6A-6ekiA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KU6_A_MZMA301_1
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 10 HIS A 119
VAL A 138
LEU A 201
THR A 202
THR A 203
 ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
None
 0.91A 5ku6A-6ekiA:
26.6		 5ku6A-6ekiA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KU6_B_MZMB302_1
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		10 / 10 GLN A 115
HIS A 117
HIS A 119
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
None
 0.34A 5ku6B-6ekiA:
27.0		 5ku6B-6ekiA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KU6_B_MZMB302_1
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 10 HIS A 119
HIS A 117
VAL A 138
LEU A 201
THR A 202
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
 1.36A 5ku6B-6ekiA:
27.0		 5ku6B-6ekiA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KU6_B_MZMB302_1
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 10 HIS A 136
HIS A 119
VAL A 148
LEU A 201
THR A 203
 ZN  A 301 (-3.2A)
ZN  A 301 (-3.3A)
None
None
None
 1.47A 5ku6B-6ekiA:
27.0		 5ku6B-6ekiA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KU6_C_MZMC301_1
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		9 / 9 GLN A 115
HIS A 117
HIS A 119
HIS A 136
VAL A 138
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
ZN  A 301 (-4.4A)
None
None
 0.34A 5ku6C-6ekiA:
26.5		 5ku6C-6ekiA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KU6_D_MZMD301_1
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		9 / 9 GLN A 115
HIS A 117
HIS A 119
HIS A 136
VAL A 138
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
ZN  A 301 (-4.4A)
None
None
 0.33A 5ku6D-6ekiA:
26.4		 5ku6D-6ekiA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KU6_D_MZMD301_1
(CARBONIC ANHYDRASE 4)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 9 HIS A 119
HIS A 117
THR A 203
THR A 202
TRP A  33
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
None
ZN  A 301 (-4.4A)
None
 1.34A 5ku6D-6ekiA:
26.4		 5ku6D-6ekiA:
16.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5M78_A_SALA304_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 7 GLN A 115
HIS A 117
VAL A 138
LEU A 201
THR A 202
THR A 203
 None
ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
None
 0.28A 5m78A-6ekiA:
30.0		 5m78A-6ekiA:
32.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OGJ_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		4 / 6 HIS A 117
HIS A 119
LEU A 201
THR A 203
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
None
None
 1.23A 5ogjA-6ekiA:
30.3		 5ogjA-6ekiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OGJ_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 6 HIS A 117
HIS A 136
VAL A 148
LEU A 201
THR A 202
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
ZN  A 301 (-4.4A)
None
 0.26A 5ogjA-6ekiA:
30.3		 5ogjA-6ekiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OGJ_B_ACTB305_0
(CARBONIC ANHYDRASE
13)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		4 / 6 HIS A 117
HIS A 119
LEU A 201
THR A 203
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
None
None
 1.22A 5ogjB-6ekiA:
29.7		 5ogjB-6ekiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OGJ_B_ACTB305_0
(CARBONIC ANHYDRASE
13)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 6 HIS A 117
HIS A 136
VAL A 148
LEU A 201
THR A 202
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
ZN  A 301 (-4.4A)
None
 0.26A 5ogjB-6ekiA:
29.7		 5ogjB-6ekiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OHH_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		4 / 5 HIS A 117
HIS A 119
LEU A 201
THR A 203
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
None
None
 1.23A 5ohhA-6ekiA:
29.7		 5ohhA-6ekiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OHH_A_ACTA307_0
(CARBONIC ANHYDRASE
13)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 5 HIS A 117
HIS A 136
VAL A 148
LEU A 201
THR A 202
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
ZN  A 301 (-4.4A)
 0.26A 5ohhA-6ekiA:
29.7		 5ohhA-6ekiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OHH_B_ACTB311_0
(CARBONIC ANHYDRASE
13)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		4 / 6 HIS A 117
HIS A 119
LEU A 201
THR A 203
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
None
None
 1.23A 5ohhB-6ekiA:
30.3		 5ohhB-6ekiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OHH_B_ACTB311_0
(CARBONIC ANHYDRASE
13)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		4 / 6 HIS A 117
HIS A 136
LEU A 146
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
 1.30A 5ohhB-6ekiA:
30.3		 5ohhB-6ekiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OHH_B_ACTB311_0
(CARBONIC ANHYDRASE
13)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 6 HIS A 117
HIS A 136
VAL A 148
LEU A 201
THR A 202
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
ZN  A 301 (-4.4A)
None
 0.24A 5ohhB-6ekiA:
30.3		 5ohhB-6ekiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		9 / 10 HIS A 117
HIS A 119
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
PRO A 205
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
None
 0.40A 5tt3A-6ekiA:
30.4		 5tt3A-6ekiA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_A_EZLA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 10 HIS A 119
VAL A 138
LEU A 201
THR A 202
PRO A 205
 ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
None
 0.85A 5tt3A-6ekiA:
30.4		 5tt3A-6ekiA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_B_EZLB303_1
(ALPHA-CARBONIC
ANHYDRASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		8 / 9 HIS A 117
HIS A 119
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
 0.30A 5tt3B-6ekiA:
28.3		 5tt3B-6ekiA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_C_EZLC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		9 / 10 HIS A 117
HIS A 119
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
PRO A 205
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
None
 0.34A 5tt3C-6ekiA:
30.4		 5tt3C-6ekiA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_C_EZLC303_1
(ALPHA-CARBONIC
ANHYDRASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 10 HIS A 119
VAL A 138
LEU A 201
THR A 202
PRO A 205
 ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
None
 0.79A 5tt3C-6ekiA:
30.4		 5tt3C-6ekiA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_E_EZLE303_1
(ALPHA-CARBONIC
ANHYDRASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		8 / 9 HIS A 117
HIS A 119
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
 0.33A 5tt3E-6ekiA:
30.6		 5tt3E-6ekiA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_E_EZLE303_1
(ALPHA-CARBONIC
ANHYDRASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 9 HIS A 119
HIS A 136
VAL A 148
LEU A 201
THR A 202
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
ZN  A 301 (-4.4A)
 1.05A 5tt3E-6ekiA:
30.6		 5tt3E-6ekiA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		8 / 8 HIS A 117
HIS A 119
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
 0.42A 5tt3F-6ekiA:
29.7		 5tt3F-6ekiA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 8 HIS A 117
HIS A 119
VAL A 138
LEU A 201
THR A 203
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
None
None
None
 1.48A 5tt3F-6ekiA:
29.7		 5tt3F-6ekiA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_F_EZLF302_1
(ALPHA-CARBONIC
ANHYDRASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 8 HIS A 119
HIS A 136
VAL A 138
LEU A 201
THR A 202
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
ZN  A 301 (-4.4A)
 0.95A 5tt3F-6ekiA:
29.7		 5tt3F-6ekiA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_G_EZLG303_1
(ALPHA-CARBONIC
ANHYDRASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		8 / 9 HIS A 117
HIS A 119
HIS A 136
VAL A 138
VAL A 148
LEU A 201
THR A 202
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
None
ZN  A 301 (-4.4A)
None
 0.32A 5tt3G-6ekiA:
29.4		 5tt3G-6ekiA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		7 / 8 HIS A 117
HIS A 119
HIS A 136
VAL A 138
LEU A 201
THR A 202
TRP A 212
 ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
ZN  A 301 (-3.2A)
None
None
ZN  A 301 (-4.4A)
None
 0.46A 5tt3H-6ekiA:
29.8		 5tt3H-6ekiA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_A_HFGA1003_1
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		3 / 3 GLU A 134
TRP A 212
HIS A 117
 None
None
ZN  A 301 (-3.3A)
 1.11A 5xipA-6ekiA:
undetectable		 5xipA-6ekiA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZMQ_I_PACI1_0
(SERINE PROTEASE NS3
SERINE PROTEASE
SUBUNIT NS2B
PEPTIDE
PAC-DLY-DLY-DAR)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		3 / 3 VAL A 214
TYR A 195
GLU A 134
 None
 0.91A 5zmqD-6ekiA:
undetectable
5zmqE-6ekiA:
undetectable		 5zmqD-6ekiA:
undetectable
5zmqE-6ekiA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BBS_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		10 / 12 TRP A  33
ASN A  90
HIS A  92
GLN A 115
HIS A 117
HIS A 119
LEU A 201
THR A 202
THR A 203
TRP A 212
 None
None
None
None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
None
ZN  A 301 (-4.4A)
None
None
 0.65A 6bbsA-6ekiA:
23.8		 6bbsA-6ekiA:
32.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BC9_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		11 / 12 TRP A  33
ASN A  90
GLN A 115
HIS A 117
HIS A 119
VAL A 138
LEU A 201
THR A 202
THR A 203
PRO A 205
TRP A 212
 None
None
None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
None
None
None
 0.56A 6bc9A-6ekiA:
30.0		 6bc9A-6ekiA:
32.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BC9_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 12 TRP A  33
HIS A 117
LEU A 201
THR A 203
PRO A 205
TRP A 212
 None
ZN  A 301 (-3.3A)
None
None
None
None
 1.35A 6bc9A-6ekiA:
30.0		 6bc9A-6ekiA:
32.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BC9_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 12 TRP A  33
HIS A 119
VAL A 148
LEU A 201
THR A 203
PRO A 205
 None
ZN  A 301 (-3.3A)
None
None
None
None
 1.21A 6bc9A-6ekiA:
30.0		 6bc9A-6ekiA:
32.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BC9_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		7 / 12 TRP A  44
HIS A 117
HIS A 119
VAL A 138
LEU A 201
THR A 203
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
None
None
None
None
 1.45A 6bc9A-6ekiA:
30.0		 6bc9A-6ekiA:
32.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BC9_A_ETSA302_2
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		5 / 5 HIS A  92
GLU A 123
HIS A 136
LEU A 146
VAL A 148
 None
ZN  A 301 ( 4.7A)
ZN  A 301 (-3.2A)
None
None
 0.28A 6bc9A-6ekiA:
undetectable		 6bc9A-6ekiA:
32.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		10 / 12 GLN A 115
HIS A 117
HIS A 119
VAL A 138
VAL A 148
LEU A 201
THR A 202
THR A 203
PRO A 205
TRP A 212
 None
ZN  A 301 (-3.3A)
ZN  A 301 (-3.3A)
None
None
None
ZN  A 301 (-4.4A)
None
None
None
 0.28A 6bccA-6ekiA:
30.0		 6bccA-6ekiA:
32.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 12 HIS A 119
LEU A 201
THR A 202
THR A 203
PRO A 205
TRP A 212
 ZN  A 301 (-3.3A)
None
ZN  A 301 (-4.4A)
None
None
None
 1.39A 6bccA-6ekiA:
30.0		 6bccA-6ekiA:
32.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6BCC_A_EZLA302_1
(CARBONIC ANHYDRASE 2)		 6eki CARBONIC ANHYDRASE
(Persephonella
marina) 		6 / 12 HIS A 119
VAL A 138
LEU A 201
THR A 202
THR A 203
PRO A 205
 ZN  A 301 (-3.3A)
None
None
ZN  A 301 (-4.4A)
None
None
 0.88A 6bccA-6ekiA:
30.0		 6bccA-6ekiA:
32.14