SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6el1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I6V_C_RFPC1640_1
(DNA-DIRECTED RNA
POLYMERASE)		 6el1 YAXB
(Yersinia
enterocolitica) 		5 / 12 GLN O  34
LEU O  48
SER O  51
GLU O 290
ILE O  29
 None
 1.37A 1i6vC-6el1O:
undetectable		 1i6vC-6el1O:
5.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IDW_B_017B401_1
(PROTEASE)		 6el1 YAXB
(Yersinia
enterocolitica) 		5 / 11 LEU O  32
ALA O  47
ILE O 145
ALA O 283
ILE O 287
 None
 1.13A 2idwA-6el1O:
undetectable		 2idwA-6el1O:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_D_TOPD1158_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 6el1 YAXB
(Yersinia
enterocolitica) 		5 / 10 ALA O 298
LEU O 133
ILE O  17
SER O  64
PHE O  19
 None
 1.20A 2w9sD-6el1O:
undetectable		 2w9sD-6el1O:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_E_TOPE1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 6el1 YAXB
(Yersinia
enterocolitica) 		4 / 8 ILE O  17
ALA O 298
LEU O  57
PHE O  19
 None
 0.80A 2w9sE-6el1O:
undetectable		 2w9sE-6el1O:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_F_TOPF1159_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 6el1 YAXB
(Yersinia
enterocolitica) 		5 / 10 ALA O 298
LEU O 133
ILE O  17
SER O  64
PHE O  19
 None
 1.21A 2w9sF-6el1O:
undetectable		 2w9sF-6el1O:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB512_2
(PHOSPHOLIPASE A2)		 6el1 YAXB
(Yersinia
enterocolitica) 		4 / 7 VAL O 197
LYS O 201
ILE O 204
GLY O 207
 None
 0.75A 3bjwB-6el1O:
undetectable		 3bjwB-6el1O:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JQ7_B_DX2B271_1
(PTERIDINE REDUCTASE
1)		 6el1 YAXB
(Yersinia
enterocolitica) 		4 / 8 SER O  23
PHE O  19
LEU O 133
TRP O 305
 None
 1.25A 3jq7B-6el1O:
undetectable		 3jq7B-6el1O:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA5_B_06XB501_1
(CYTOCHROME P450 2B6)		 6el1 YAXB
(Yersinia
enterocolitica) 		4 / 7 ILE O 145
ILE O 285
GLU O 156
VAL O  40
 None
 0.88A 3ua5B-6el1O:
2.5		 3ua5B-6el1O:
10.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB0_B_ACTB401_0
(UNCHARACTERIZED
PROTEIN)		 6el1 YAXB
(Yersinia
enterocolitica) 		4 / 5 VAL O 294
LEU O  57
VAL O  61
PHE O  22
 None
 1.04A 4lb0B-6el1O:
undetectable		 4lb0B-6el1O:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWV_A_ACAA18_2
(SCRFP-TAG,GP41)		 6el1 YAXB
(Yersinia
enterocolitica) 		4 / 7 GLN O 160
LEU O 163
ASP O 166
LEU O 172
 None
 0.86A 5nwvA-6el1O:
undetectable		 5nwvA-6el1O:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA411_0
(UNCHARACTERIZED
PROTEIN KDOO)		 6el1 YAXB
(Yersinia
enterocolitica) 		3 / 3 LYS O 101
LEU O  91
ARG O 108
 None
 0.94A 5yw0A-6el1O:
undetectable		 5yw0A-6el1O:
undetectable