SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6el8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A28_B_STRB2_1
(PROGESTERONE
RECEPTOR)		 6el8 FORKHEAD BOX PROTEIN
N1
(Homo
sapiens) 		5 / 12 LEU A 322
ASN A 321
LEU A 278
MET A 354
CYH A 327
 None
 1.24A 1a28B-6el8A:
undetectable		 1a28B-6el8A:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQN_A_NDRA1001_0
(PROGESTERONE
RECEPTOR)		 6el8 FORKHEAD BOX PROTEIN
N1
(Homo
sapiens) 		5 / 12 LEU A 322
ASN A 321
LEU A 278
MET A 354
CYH A 327
 None
 1.27A 1sqnA-6el8A:
undetectable		 1sqnA-6el8A:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_A_STRA1001_1
(MINERALOCORTICOID
RECEPTOR)		 6el8 FORKHEAD BOX PROTEIN
N1
(Homo
sapiens) 		5 / 12 LEU A 322
ASN A 321
LEU A 278
MET A 354
CYH A 327
 None
 1.30A 1ya3A-6el8A:
undetectable		 1ya3A-6el8A:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AA5_B_STRB302_1
(MINERALOCORTICOID
RECEPTOR)		 6el8 FORKHEAD BOX PROTEIN
N1
(Homo
sapiens) 		5 / 12 LEU A 322
ASN A 321
LEU A 278
MET A 354
CYH A 327
 None
 1.26A 2aa5B-6el8A:
undetectable		 2aa5B-6el8A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_A_SNLA1001_1
(MINERALOCORTICOID
RECEPTOR)		 6el8 FORKHEAD BOX PROTEIN
N1
(Homo
sapiens) 		5 / 12 LEU A 322
ASN A 321
LEU A 278
LEU A 346
CYH A 327
 None
 1.40A 2oaxA-6el8A:
undetectable		 2oaxA-6el8A:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_B_SNLB2001_1
(MINERALOCORTICOID
RECEPTOR)		 6el8 FORKHEAD BOX PROTEIN
N1
(Homo
sapiens) 		5 / 12 LEU A 322
ASN A 321
LEU A 278
MET A 354
CYH A 327
 None
 1.30A 2oaxB-6el8A:
undetectable		 2oaxB-6el8A:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_B_NDRB1000_0
(PROGESTERONE
RECEPTOR)		 6el8 FORKHEAD BOX PROTEIN
N1
(Homo
sapiens) 		5 / 12 LEU A 322
ASN A 321
LEU A 278
MET A 354
CYH A 327
 None
 1.26A 2w8yB-6el8A:
undetectable		 2w8yB-6el8A:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		 6el8 FORKHEAD BOX PROTEIN
N1
(Homo
sapiens) 		5 / 12 LEU A 322
ASN A 321
LEU A 278
MET A 354
CYH A 327
 None
 1.32A 3d90A-6el8A:
undetectable		 3d90A-6el8A:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKX_A_198A1002_2
(ANDROGEN RECEPTOR)		 6el8 FORKHEAD BOX PROTEIN
N1
(Homo
sapiens) 		4 / 6 LEU A 322
ASN A 321
LEU A 283
ILE A 277
 None
 1.06A 4okxA-6el8A:
undetectable		 4okxA-6el8A:
14.69