SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6elj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 6elj FAB HEAVY CHAIN
(Homo
sapiens) 		5 / 12 SER A 199
GLY A 145
THR A 146
ALA A 147
THR A 142
 None
 0.79A 4qvpH-6eljA:
undetectable
4qvpI-6eljA:
undetectable		 4qvpH-6eljA:
20.39
4qvpI-6eljA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 6elj FAB HEAVY CHAIN
(Homo
sapiens) 		5 / 12 SER A 199
GLY A 145
THR A 146
ALA A 147
THR A 142
 None
 0.79A 4qvpV-6eljA:
undetectable
4qvpW-6eljA:
undetectable		 4qvpV-6eljA:
20.39
4qvpW-6eljA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 6elj FAB HEAVY CHAIN
(Homo
sapiens) 		5 / 11 SER A 199
GLY A 145
THR A 146
ALA A 147
THR A 142
 None
 0.83A 4qvvH-6eljA:
undetectable		 4qvvH-6eljA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 6elj FAB HEAVY CHAIN
(Homo
sapiens) 		5 / 11 SER A 199
GLY A 145
THR A 146
ALA A 147
THR A 142
 None
 0.83A 4qvvV-6eljA:
undetectable		 4qvvV-6eljA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 6elj FAB HEAVY CHAIN
(Homo
sapiens) 		5 / 11 SER A 199
GLY A 145
THR A 146
ALA A 147
THR A 142
 None
 0.82A 4qvyH-6eljA:
undetectable		 4qvyH-6eljA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVY_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 6elj FAB HEAVY CHAIN
(Homo
sapiens) 		5 / 12 SER A 199
GLY A 145
THR A 146
ALA A 147
THR A 142
 None
 0.82A 4qvyV-6eljA:
undetectable
4qvyW-6eljA:
undetectable		 4qvyV-6eljA:
20.39
4qvyW-6eljA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 6elj FAB HEAVY CHAIN
(Homo
sapiens) 		5 / 11 SER A 199
GLY A 145
THR A 146
ALA A 147
THR A 142
 None
 0.82A 4qw0H-6eljA:
undetectable
4qw0I-6eljA:
undetectable		 4qw0H-6eljA:
20.39
4qw0I-6eljA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 6elj FAB HEAVY CHAIN
(Homo
sapiens) 		5 / 11 SER A 199
GLY A 145
THR A 146
ALA A 147
THR A 142
 None
 0.82A 4qw0V-6eljA:
undetectable
4qw0W-6eljA:
undetectable		 4qw0V-6eljA:
20.39
4qw0W-6eljA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 6elj FAB HEAVY CHAIN
(Homo
sapiens) 		5 / 11 SER A 199
GLY A 145
THR A 146
ALA A 147
THR A 142
 None
 0.81A 5bxnH-6eljA:
undetectable
5bxnI-6eljA:
undetectable		 5bxnH-6eljA:
21.65
5bxnI-6eljA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 6elj FAB HEAVY CHAIN
(Homo
sapiens) 		5 / 12 SER A 199
GLY A 145
THR A 146
ALA A 147
THR A 142
 None
 0.82A 5cz7V-6eljA:
undetectable
5cz7W-6eljA:
undetectable		 5cz7V-6eljA:
20.39
5cz7W-6eljA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2)		 6elj FAB HEAVY CHAIN
(Homo
sapiens) 		5 / 11 SER A 199
GLY A 145
THR A 146
ALA A 147
THR A 142
 None
 0.81A 5d0xV-6eljA:
undetectable		 5d0xV-6eljA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 6elj FAB HEAVY CHAIN
(Homo
sapiens) 		5 / 12 SER A 199
GLY A 145
THR A 146
ALA A 147
THR A 142
 None
 0.78A 5l5fH-6eljA:
undetectable
5l5fI-6eljA:
undetectable		 5l5fH-6eljA:
20.39
5l5fI-6eljA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 6elj FAB HEAVY CHAIN
(Homo
sapiens) 		5 / 12 SER A 199
GLY A 145
THR A 146
ALA A 147
THR A 142
 None
 0.78A 5l5fV-6eljA:
undetectable
5l5fW-6eljA:
undetectable		 5l5fV-6eljA:
20.39
5l5fW-6eljA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_H_BO2H301_0
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 6elj FAB HEAVY CHAIN
(Homo
sapiens) 		5 / 12 SER A 199
GLY A 145
THR A 146
ALA A 147
THR A 142
 None
 0.91A 6hwdH-6eljA:
undetectable
6hwdI-6eljA:
undetectable		 6hwdH-6eljA:
17.50
6hwdI-6eljA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_V_BO2V301_0
(PROTEASOME SUBUNIT
BETA TYPE-2)		 6elj FAB HEAVY CHAIN
(Homo
sapiens) 		5 / 11 SER A 199
GLY A 145
THR A 146
ALA A 147
THR A 142
 None
 0.91A 6hwdV-6eljA:
undetectable		 6hwdV-6eljA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 6elj FAB HEAVY CHAIN
(Homo
sapiens) 		4 / 5 ILE A  48
LEU A  64
ARG A  19
LEU A  86
 None
 0.87A 6nmpN-6eljA:
undetectable
6nmpW-6eljA:
undetectable		 6nmpN-6eljA:
17.57
6nmpW-6eljA:
15.21