SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6elu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_1
(NON-STRUCTURAL
PROTEIN 5)		 6elu SERUM RESISTANCE
ASSOCIATED
VSG PROTEIN
(Trypanosoma
brucei) 		3 / 3 SER A  66
HIS A 129
ASP A 135
 None
 0.73A 2wa2B-6eluA:
undetectable		 2wa2B-6eluA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S43_A_478A401_1
(PROTEASE)		 6elu VSG PROTEIN
SERUM RESISTANCE
ASSOCIATED
(Trypanosoma
brucei) 		5 / 9 ALA A 120
ILE A 130
GLY A  52
ILE A  53
ILE A 115
 None
 1.00A 3s43A-6eluA:
undetectable		 3s43A-6eluA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_D_ACTD305_0
(CARBONIC ANHYDRASE 4)		 6elu SERUM RESISTANCE
ASSOCIATED
VSG PROTEIN
(Trypanosoma
brucei) 		4 / 5 ALA A 116
ALA A  54
ILE A 134
LEU A 137
 None
 0.76A 5jncD-6eluA:
undetectable		 5jncD-6eluA:
undetectable