SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6emr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KNY_B_KANB559_1
(KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE)		 6emr -
(-) 		4 / 8 GLU A 507
SER A 511
ASP A 514
GLU A 509
 None
 1.17A 1knyA-6emrA:
undetectable
1knyB-6emrA:
undetectable		 1knyA-6emrA:
undetectable
1knyB-6emrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_A_BEZA1001_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 6emr -
(-) 		4 / 6 VAL A 411
SER A 409
LEU A 377
PHE A 406
 None
 1.27A 2f8dA-6emrA:
undetectable		 2f8dA-6emrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MS4_A_2C0A501_1
(GAMMA-AMINOBUTYRIC
ACID TYPE B RECEPTOR
SUBUNIT 1)		 6emr -
(-) 		4 / 8 SER A 350
SER A 347
TRP A 344
GLU A 345
 None
 1.35A 4ms4A-6emrA:
undetectable		 4ms4A-6emrA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GTR_A_ESTA601_2
(ESTROGEN RECEPTOR)		 6emr -
(-) 		4 / 5 LEU A 377
PHE A 488
LEU A 363
HIS A 356
 None
 0.91A 5gtrA-6emrA:
undetectable		 5gtrA-6emrA:
undetectable