SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6emz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOU_A_CQAA403_0
(HISTAMINE
N-METHYLTRANSFERASE)		 6emz INT PROTEIN
(Enterococcus
faecalis) 		4 / 8 ASP A 234
GLY A 231
ASP A 298
TYR A 300
 None
 0.94A 2aouA-6emzA:
undetectable		 2aouA-6emzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_B_ADNB438_2
(ADENOSYLHOMOCYSTEINA
SE)		 6emz INT PROTEIN
(Enterococcus
faecalis) 		3 / 3 THR A 222
GLU A 228
HIS A 248
 None
 0.82A 3g1uB-6emzA:
undetectable		 3g1uB-6emzA:
11.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_C_ADNC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 6emz INT PROTEIN
(Enterococcus
faecalis) 		4 / 5 LEU A 224
THR A 222
GLU A 228
HIS A 248
 None
 1.27A 3n58C-6emzA:
undetectable		 3n58C-6emzA:
9.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_L_CLML221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6emz INT PROTEIN
(Enterococcus
faecalis) 		5 / 12 CYH A 121
SER A 129
LEU A 118
VAL A  84
PHE A 159
 None
 1.49A 3u9fJ-6emzA:
undetectable
3u9fL-6emzA:
undetectable		 3u9fJ-6emzA:
undetectable
3u9fL-6emzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_2_BEZ2801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 6emz INT PROTEIN
(Enterococcus
faecalis) 		4 / 4 LEU A 354
ARG A 270
ILE A 367
ILE A 272
 None
 1.35A 5dzk2-6emzA:
undetectable
5dzkM-6emzA:
undetectable
5dzkN-6emzA:
undetectable		 5dzk2-6emzA:
undetectable
5dzkM-6emzA:
undetectable
5dzkN-6emzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_2_BEZ2801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 6emz INT PROTEIN
(Enterococcus
faecalis) 		4 / 4 LEU A 364
ARG A 270
ILE A 367
ILE A 272
 None
 1.35A 5dzk2-6emzA:
undetectable
5dzkM-6emzA:
undetectable
5dzkN-6emzA:
undetectable		 5dzk2-6emzA:
undetectable
5dzkM-6emzA:
undetectable
5dzkN-6emzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_V_BEZV801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 6emz INT PROTEIN
(Enterococcus
faecalis) 		4 / 4 ILE A 367
ILE A 272
ARG A 270
LEU A 354
 None
 1.26A 5dzkh-6emzA:
undetectable
5dzkn-6emzA:
undetectable
5dzkv-6emzA:
undetectable		 5dzkh-6emzA:
undetectable
5dzkn-6emzA:
undetectable
5dzkv-6emzA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJC_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 6emz INT PROTEIN
(Enterococcus
faecalis) 		4 / 7 LEU A 200
ILE A 244
THR A 222
MET A 274
 None
 1.12A 5ljcA-6emzA:
undetectable		 5ljcA-6emzA:
undetectable