SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6en3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EUP_A_ASDA452_1
(CYTOCHROME P450ERYF)		 6en3 ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
F2,MULTIFUNCTIONAL-A
UTOPROCESSING
REPEATS-IN-TOXIN
(Streptococcus
pyogenes;
Vibrio
cholerae) 		4 / 8 PHE A 811
ILE A 919
LEU A 920
LEU A 917
 None
 0.77A 1eupA-6en3A:
undetectable		 1eupA-6en3A:
9.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I18_A_RBFA98_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 6en3 ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
F2,MULTIFUNCTIONAL-A
UTOPROCESSING
REPEATS-IN-TOXIN
(Streptococcus
pyogenes;
Vibrio
cholerae) 		5 / 10 LEU A 518
LEU A 565
ILE A 618
PHE A 573
ILE A 594
 None
 1.35A 1i18A-6en3A:
undetectable
1i18B-6en3A:
undetectable		 1i18A-6en3A:
19.59
1i18B-6en3A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I18_B_RBFB99_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 6en3 ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
F2,MULTIFUNCTIONAL-A
UTOPROCESSING
REPEATS-IN-TOXIN
(Streptococcus
pyogenes;
Vibrio
cholerae) 		5 / 10 PHE A 573
ILE A 594
LEU A 518
LEU A 565
ILE A 618
 None
 1.39A 1i18A-6en3A:
undetectable
1i18B-6en3A:
undetectable		 1i18A-6en3A:
19.59
1i18B-6en3A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5R_A_RBFA859_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 6en3 ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
F2,MULTIFUNCTIONAL-A
UTOPROCESSING
REPEATS-IN-TOXIN
(Streptococcus
pyogenes;
Vibrio
cholerae) 		5 / 11 ASN A 677
PHE A 666
TYR A 640
GLY A 645
TYR A 644
 None
 1.50A 1l5rA-6en3A:
undetectable		 1l5rA-6en3A:
7.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_B_THAB2_1
(LIVER
CARBOXYLESTERASE I)		 6en3 ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
F2,MULTIFUNCTIONAL-A
UTOPROCESSING
REPEATS-IN-TOXIN
(Streptococcus
pyogenes;
Vibrio
cholerae) 		5 / 11 LEU A 463
LEU A 518
LEU A 485
LEU A 487
MET A 527
 None
 1.21A 1mx1B-6en3A:
undetectable		 1mx1B-6en3A:
8.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_B_THAB2_1
(LIVER
CARBOXYLESTERASE I)		 6en3 ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
F2,MULTIFUNCTIONAL-A
UTOPROCESSING
REPEATS-IN-TOXIN
(Streptococcus
pyogenes;
Vibrio
cholerae) 		5 / 11 LEU A 518
VAL A 467
LEU A 463
LEU A 557
LEU A 523
 None
 1.16A 1mx1B-6en3A:
undetectable		 1mx1B-6en3A:
8.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_B_CHDB1130_0
(FATTY ACID-BINDING
PROTEIN)		 6en3 ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
F2,MULTIFUNCTIONAL-A
UTOPROCESSING
REPEATS-IN-TOXIN
(Vibrio
cholerae;
Streptococcus
pyogenes) 		5 / 12 LEU A 586
LEU A 562
LEU A 568
ILE A 610
ILE A 510
 None
 1.26A 1tw4B-6en3A:
undetectable		 1tw4B-6en3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XL6_B_SPMB3001_1
(INWARD RECTIFIER
POTASSIUM CHANNEL)		 6en3 ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
F2,MULTIFUNCTIONAL-A
UTOPROCESSING
REPEATS-IN-TOXIN
(Streptococcus
pyogenes;
Vibrio
cholerae) 		4 / 5 ALA A 684
TYR A 685
ALA A 680
TYR A 682
 None
 1.01A 1xl6A-6en3A:
2.2
1xl6B-6en3A:
undetectable		 1xl6A-6en3A:
10.96
1xl6B-6en3A:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXK_A_IMNA2001_1
(SERUM ALBUMIN)		 6en3 ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
F2,MULTIFUNCTIONAL-A
UTOPROCESSING
REPEATS-IN-TOXIN
(Streptococcus
pyogenes;
Vibrio
cholerae) 		4 / 8 SER A 887
PHE A 825
ALA A 829
LEU A 792
 None
 1.11A 2bxkA-6en3A:
4.1		 2bxkA-6en3A:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2LBD_A_REAA500_1
(RETINOIC ACID
RECEPTOR GAMMA)		 6en3 ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
F2,MULTIFUNCTIONAL-A
UTOPROCESSING
REPEATS-IN-TOXIN
(Streptococcus
pyogenes;
Vibrio
cholerae) 		5 / 12 LEU A 230
ARG A 181
ILE A 180
PHE A 148
GLY A 266
 None
MAN  A1305 ( 4.7A)
None
None
None
 1.21A 2lbdA-6en3A:
undetectable		 2lbdA-6en3A:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_B_9CRB502_1
(CYTOCHROME P450 2C8)		 6en3 ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
F2,MULTIFUNCTIONAL-A
UTOPROCESSING
REPEATS-IN-TOXIN
(Streptococcus
pyogenes;
Vibrio
cholerae) 		5 / 10 ILE A 336
ILE A 290
LEU A 300
VAL A 234
ILE A 277
 None
 1.25A 2nnhB-6en3A:
undetectable		 2nnhB-6en3A:
10.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZ7_A_CA4A1_1
(ANDROGEN RECEPTOR)		 6en3 ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
F2,MULTIFUNCTIONAL-A
UTOPROCESSING
REPEATS-IN-TOXIN
(Streptococcus
pyogenes;
Vibrio
cholerae) 		5 / 12 LEU A 172
ASN A 173
GLY A 176
LEU A 227
MET A 106
 None
 0.99A 2oz7A-6en3A:
undetectable		 2oz7A-6en3A:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_A_486A1000_2
(PROGESTERONE
RECEPTOR)		 6en3 ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
F2,MULTIFUNCTIONAL-A
UTOPROCESSING
REPEATS-IN-TOXIN
(Streptococcus
pyogenes;
Vibrio
cholerae) 		4 / 7 LEU A 570
ASN A 597
GLU A 576
MET A 614
 None
 1.21A 2w8yA-6en3A:
undetectable		 2w8yA-6en3A:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WA2_B_SAMB1267_1
(NON-STRUCTURAL
PROTEIN 5)		 6en3 ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
F2,MULTIFUNCTIONAL-A
UTOPROCESSING
REPEATS-IN-TOXIN
(Vibrio
cholerae;
Streptococcus
pyogenes) 		3 / 3 SER A 708
HIS A 701
ASP A 697
 None
 0.77A 2wa2B-6en3A:
undetectable		 2wa2B-6en3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WLK_B_SPMB1302_1
(ATP-SENSITIVE INWARD
RECTIFIER POTASSIUM
CHANNEL 10)		 6en3 ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
F2,MULTIFUNCTIONAL-A
UTOPROCESSING
REPEATS-IN-TOXIN
(Streptococcus
pyogenes;
Vibrio
cholerae) 		4 / 4 ALA A 684
TYR A 685
ALA A 680
TYR A 682
 None
 1.02A 2wlkA-6en3A:
2.5
2wlkB-6en3A:
2.2		 2wlkA-6en3A:
10.96
2wlkB-6en3A:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_A_DGXA1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)		 6en3 ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
F2,MULTIFUNCTIONAL-A
UTOPROCESSING
REPEATS-IN-TOXIN
(Streptococcus
pyogenes;
Vibrio
cholerae) 		3 / 3 TRP A 870
VAL A 787
ARG A 830
 None
 0.98A 3b0wA-6en3A:
undetectable		 3b0wA-6en3A:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1000_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 6en3 ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
F2,MULTIFUNCTIONAL-A
UTOPROCESSING
REPEATS-IN-TOXIN
(Streptococcus
pyogenes;
Vibrio
cholerae) 		4 / 6 GLU A  67
LYS A  70
LYS A  77
GLU A  74
 None
 1.12A 4a7tA-6en3A:
undetectable		 4a7tA-6en3A:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BVA_A_T3A1314_1
(THIOMORPHOLINE-CARBO
XYLATE DEHYDROGENASE)		 6en3 ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
F2,MULTIFUNCTIONAL-A
UTOPROCESSING
REPEATS-IN-TOXIN
(Streptococcus
pyogenes;
Vibrio
cholerae) 		5 / 12 VAL A 436
GLY A 408
VAL A 409
HIS A 411
SER A 346
 None
None
None
None
NAG  A1303 ( 4.9A)
 1.23A 4bvaA-6en3A:
undetectable		 4bvaA-6en3A:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D9H_A_ADNA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 6en3 ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
F2,MULTIFUNCTIONAL-A
UTOPROCESSING
REPEATS-IN-TOXIN
(Streptococcus
pyogenes;
Vibrio
cholerae) 		5 / 11 ARG A 520
SER A 571
GLY A 596
SER A 595
ASP A 632
 None
 1.15A 4d9hA-6en3A:
undetectable		 4d9hA-6en3A:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAN_A_2FAA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 6en3 ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
F2,MULTIFUNCTIONAL-A
UTOPROCESSING
REPEATS-IN-TOXIN
(Streptococcus
pyogenes;
Vibrio
cholerae) 		5 / 11 ARG A 520
SER A 571
GLY A 596
SER A 595
ASP A 632
 None
 1.20A 4danA-6en3A:
undetectable		 4danA-6en3A:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAN_B_2FAB301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 6en3 ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
F2,MULTIFUNCTIONAL-A
UTOPROCESSING
REPEATS-IN-TOXIN
(Streptococcus
pyogenes;
Vibrio
cholerae) 		5 / 12 ARG A 520
SER A 571
GLY A 596
SER A 595
ASP A 632
 None
 1.15A 4danA-6en3A:
undetectable
4danB-6en3A:
undetectable		 4danA-6en3A:
17.47
4danB-6en3A:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJW_A_SRYA2001_2
(TRANSCRIPTIONAL
REGULATOR TCAR)		 6en3 ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
F2,MULTIFUNCTIONAL-A
UTOPROCESSING
REPEATS-IN-TOXIN
(Streptococcus
pyogenes;
Vibrio
cholerae) 		4 / 6 GLU A 606
ILE A 610
ASN A 607
VAL A 555
 None
 1.08A 4ejwB-6en3A:
undetectable		 4ejwB-6en3A:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA302_1
(CHITOSANASE)		 6en3 ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
F2,MULTIFUNCTIONAL-A
UTOPROCESSING
REPEATS-IN-TOXIN
(Streptococcus
pyogenes;
Vibrio
cholerae) 		4 / 5 ARG A 608
THR A 605
ASP A 600
TYR A 685
 None
 1.33A 4oltA-6en3A:
undetectable		 4oltA-6en3A:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB302_1
(CHITOSANASE)		 6en3 ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
F2,MULTIFUNCTIONAL-A
UTOPROCESSING
REPEATS-IN-TOXIN
(Streptococcus
pyogenes;
Vibrio
cholerae) 		4 / 5 ARG A 608
THR A 605
ASP A 600
TYR A 685
 None
 1.34A 4oltB-6en3A:
undetectable		 4oltB-6en3A:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA302_1
(CHITOSANASE)		 6en3 ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
F2,MULTIFUNCTIONAL-A
UTOPROCESSING
REPEATS-IN-TOXIN
(Streptococcus
pyogenes;
Vibrio
cholerae) 		4 / 5 ARG A 608
THR A 605
ASP A 600
TYR A 685
 None
 1.32A 4qwpA-6en3A:
undetectable		 4qwpA-6en3A:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB306_1
(CHITOSANASE)		 6en3 ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
F2,MULTIFUNCTIONAL-A
UTOPROCESSING
REPEATS-IN-TOXIN
(Streptococcus
pyogenes;
Vibrio
cholerae) 		4 / 5 ARG A 608
THR A 605
ASP A 600
TYR A 685
 None
 1.34A 4qwpB-6en3A:
undetectable		 4qwpB-6en3A:
15.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA303_0
(THAUMATIN-1)		 6en3 ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
F2,MULTIFUNCTIONAL-A
UTOPROCESSING
REPEATS-IN-TOXIN
(Vibrio
cholerae;
Streptococcus
pyogenes) 		4 / 7 LEU A 962
SER A 965
ILE A 976
VAL A 973
 None
 1.23A 4tvtA-6en3A:
undetectable		 4tvtA-6en3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_B_CHDB102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 6en3 ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
F2,MULTIFUNCTIONAL-A
UTOPROCESSING
REPEATS-IN-TOXIN
(Vibrio
cholerae;
Streptococcus
pyogenes) 		5 / 11 ARG A 274
LEU A 275
LEU A 109
ALA A 147
LEU A 146
 None
 0.90A 4wg0B-6en3A:
undetectable
4wg0C-6en3A:
undetectable
4wg0D-6en3A:
undetectable		 4wg0B-6en3A:
undetectable
4wg0C-6en3A:
undetectable
4wg0D-6en3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_D_CHDD102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 6en3 ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
F2,MULTIFUNCTIONAL-A
UTOPROCESSING
REPEATS-IN-TOXIN
(Vibrio
cholerae;
Streptococcus
pyogenes) 		5 / 11 ARG A 274
LEU A 275
LEU A 109
ALA A 147
LEU A 146
 None
 0.91A 4wg0D-6en3A:
undetectable
4wg0E-6en3A:
undetectable
4wg0F-6en3A:
undetectable		 4wg0D-6en3A:
undetectable
4wg0E-6en3A:
undetectable
4wg0F-6en3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_E_CHDE104_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 6en3 ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
F2,MULTIFUNCTIONAL-A
UTOPROCESSING
REPEATS-IN-TOXIN
(Vibrio
cholerae;
Streptococcus
pyogenes) 		5 / 11 ALA A 147
LEU A 146
LEU A 109
ARG A 274
LEU A 275
 None
 0.92A 4wg0C-6en3A:
undetectable
4wg0D-6en3A:
undetectable
4wg0E-6en3A:
undetectable		 4wg0C-6en3A:
undetectable
4wg0D-6en3A:
undetectable
4wg0E-6en3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_G_CHDG103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 6en3 ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
F2,MULTIFUNCTIONAL-A
UTOPROCESSING
REPEATS-IN-TOXIN
(Vibrio
cholerae;
Streptococcus
pyogenes) 		5 / 11 ALA A 147
LEU A 146
LEU A 109
ARG A 274
LEU A 275
 None
 0.88A 4wg0E-6en3A:
undetectable
4wg0F-6en3A:
undetectable
4wg0G-6en3A:
undetectable		 4wg0E-6en3A:
undetectable
4wg0F-6en3A:
undetectable
4wg0G-6en3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_I_CHDI103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 6en3 ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
F2,MULTIFUNCTIONAL-A
UTOPROCESSING
REPEATS-IN-TOXIN
(Vibrio
cholerae;
Streptococcus
pyogenes) 		5 / 11 ALA A 147
LEU A 146
LEU A 109
ARG A 274
LEU A 275
 None
 0.93A 4wg0G-6en3A:
undetectable
4wg0H-6en3A:
undetectable
4wg0I-6en3A:
undetectable		 4wg0G-6en3A:
undetectable
4wg0H-6en3A:
undetectable
4wg0I-6en3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X30_A_T44A401_1
(THYROXINE-BINDING
GLOBULIN)		 6en3 ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
F2,MULTIFUNCTIONAL-A
UTOPROCESSING
REPEATS-IN-TOXIN
(Streptococcus
pyogenes;
Vibrio
cholerae) 		5 / 9 ALA A 466
LEU A 504
LEU A 487
LEU A 485
ARG A 486
 None
 1.29A 4x30A-6en3A:
undetectable		 4x30A-6en3A:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HG0_A_SAMA301_0
(PANTOTHENATE
SYNTHETASE)		 6en3 ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
F2,MULTIFUNCTIONAL-A
UTOPROCESSING
REPEATS-IN-TOXIN
(Vibrio
cholerae;
Streptococcus
pyogenes) 		5 / 12 GLY A 115
TYR A 450
VAL A 537
GLY A 344
LEU A 146
 None
 1.07A 5hg0A-6en3A:
undetectable		 5hg0A-6en3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HG0_B_SAMB301_0
(PANTOTHENATE
SYNTHETASE)		 6en3 ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
F2,MULTIFUNCTIONAL-A
UTOPROCESSING
REPEATS-IN-TOXIN
(Vibrio
cholerae;
Streptococcus
pyogenes) 		5 / 12 GLY A 115
TYR A 450
VAL A 537
GLY A 344
LEU A 146
 None
 1.05A 5hg0B-6en3A:
undetectable		 5hg0B-6en3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 6en3 ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE
F2,MULTIFUNCTIONAL-A
UTOPROCESSING
REPEATS-IN-TOXIN
(Vibrio
cholerae;
Streptococcus
pyogenes) 		4 / 8 TYR A 709
VAL A 707
ASN A 677
ILE A 676
 None
 0.98A 6hzpA-6en3A:
undetectable		 6hzpA-6en3A:
undetectable