SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6eo2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_B_9CRB165_1
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 6eo2 TRANSCRIPTIONAL
REGULATORY PROTEIN
RCSB
(Salmonella
enterica) 		5 / 12 ILE A  19
VAL A   6
VAL A 107
ALA A 119
ILE A 103
 None
 0.99A 1epbB-6eo2A:
undetectable		 1epbB-6eo2A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9Q_A_CHDA459_0
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 6eo2 TRANSCRIPTIONAL
REGULATORY PROTEIN
RCSB
(Salmonella
enterica) 		4 / 6 ASP A  56
LEU A  86
VAL A  85
ILE A 106
 None
 0.83A 1s9qA-6eo2A:
undetectable		 1s9qA-6eo2A:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOT_A_VDNA101_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B)		 6eo2 TRANSCRIPTIONAL
REGULATORY PROTEIN
RCSB
(Salmonella
enterica) 		5 / 12 LEU A  81
ILE A  71
MET A  59
SER A  38
ILE A   7
 None
 1.28A 1xotA-6eo2A:
undetectable		 1xotA-6eo2A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXO_B_TACB1211_1
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 6eo2 TRANSCRIPTIONAL
REGULATORY PROTEIN
RCSB
(Salmonella
enterica) 		5 / 11 LEU A  81
LEU A 120
LEU A  45
ILE A  19
VAL A  31
 None
 1.22A 2uxoB-6eo2A:
2.1		 2uxoB-6eo2A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)		 6eo2 TRANSCRIPTIONAL
REGULATORY PROTEIN
RCSB
(Salmonella
enterica) 		5 / 10 LYS A  72
SER A  38
LEU A 101
ILE A  68
GLY A  67
 None
 1.35A 3ijxB-6eo2A:
undetectable
3ijxD-6eo2A:
undetectable		 3ijxB-6eo2A:
25.76
3ijxD-6eo2A:
25.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_B_HFZB800_1
(GLUTAMATE RECEPTOR 2)		 6eo2 TRANSCRIPTIONAL
REGULATORY PROTEIN
RCSB
(Salmonella
enterica) 		5 / 10 LYS A  72
SER A  38
LEU A 101
ILE A  68
GLY A  67
 None
 1.29A 3iluB-6eo2A:
undetectable
3iluE-6eo2A:
undetectable		 3iluB-6eo2A:
25.76
3iluE-6eo2A:
25.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_E_HFZE800_1
(GLUTAMATE RECEPTOR 2)		 6eo2 TRANSCRIPTIONAL
REGULATORY PROTEIN
RCSB
(Salmonella
enterica) 		5 / 11 ILE A  68
GLY A  67
LYS A  72
SER A  38
LEU A 101
 None
 1.27A 3iluB-6eo2A:
undetectable
3iluE-6eo2A:
undetectable		 3iluB-6eo2A:
25.76
3iluE-6eo2A:
25.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_C_RBFC201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 6eo2 TRANSCRIPTIONAL
REGULATORY PROTEIN
RCSB
(Salmonella
enterica) 		5 / 9 GLU A 104
LEU A  70
VAL A  98
LEU A 101
ILE A  68
 None
 1.28A 4r38C-6eo2A:
undetectable		 4r38C-6eo2A:
24.12