SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6eo5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A29_A_TFPA154_1
(CALMODULIN)		 6eo5 PPBBE-LIKE 1 D396N
(Physcomitrella
patens) 		5 / 10 GLU A 298
ALA A 285
LEU A 308
GLU A 327
GLU A 328
 None
 1.27A 1a29A-6eo5A:
0.0		 1a29A-6eo5A:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 6eo5 PPBBE-LIKE 1 D396N
(Physcomitrella
patens) 		4 / 7 MET A 289
PHE A 393
ARG A 444
ASN A 383
 None
 0.99A 1t9wA-6eo5A:
1.7		 1t9wA-6eo5A:
5.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE9_A_BEZA352_0
(D-AMINO ACID OXIDASE)		 6eo5 PPBBE-LIKE 1 D396N
(Physcomitrella
patens) 		4 / 5 TYR A 472
TYR A 471
ILE A 462
GLY A 229
 None
 1.33A 1ve9A-6eo5A:
undetectable		 1ve9A-6eo5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_B_SAMB293_0
(GLYCINE
N-METHYLTRANSFERASE)		 6eo5 PPBBE-LIKE 1 D396N
(Physcomitrella
patens) 		5 / 12 TYR A 367
ALA A 363
ASN A 460
ILE A 404
TYR A 398
 None
None
FAD  A 601 (-3.5A)
None
None
 1.34A 1xvaB-6eo5A:
undetectable		 1xvaB-6eo5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_B_SAMB293_0
(GLYCINE
N-METHYLTRANSFERASE)		 6eo5 PPBBE-LIKE 1 D396N
(Physcomitrella
patens) 		5 / 12 TYR A 367
ALA A 363
TYR A 471
ILE A 404
TYR A 398
 None
 0.82A 1xvaB-6eo5A:
undetectable		 1xvaB-6eo5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_G_BEZG2352_0
(D-AMINO-ACID OXIDASE)		 6eo5 PPBBE-LIKE 1 D396N
(Physcomitrella
patens) 		4 / 5 TYR A 472
TYR A 471
ILE A 462
GLY A 229
 None
 1.37A 2du8G-6eo5A:
undetectable		 2du8G-6eo5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_J_BEZJ3352_0
(D-AMINO-ACID OXIDASE)		 6eo5 PPBBE-LIKE 1 D396N
(Physcomitrella
patens) 		4 / 5 TYR A 472
TYR A 471
ILE A 462
GLY A 229
 None
 1.36A 2du8J-6eo5A:
undetectable		 2du8J-6eo5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IJ7_C_TPFC2471_1
(CYTOCHROME P450 121)		 6eo5 PPBBE-LIKE 1 D396N
(Physcomitrella
patens) 		4 / 8 THR A  55
VAL A  82
VAL A 126
ALA A  97
 None
 1.05A 2ij7C-6eo5A:
undetectable		 2ij7C-6eo5A:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J5M_A_ACTA1321_0
(CHLOROPEROXIDASE)		 6eo5 PPBBE-LIKE 1 D396N
(Physcomitrella
patens) 		4 / 6 PHE A 492
ILE A 104
VAL A 127
ALA A  93
 None
 0.94A 2j5mA-6eo5A:
undetectable		 2j5mA-6eo5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B235_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		 6eo5 PPBBE-LIKE 1 D396N
(Physcomitrella
patens) 		4 / 6 PHE A 241
PHE A 243
GLY A 184
GLY A 185
 None
None
None
FAD  A 601 (-3.5A)
 0.77A 2qr2A-6eo5A:
undetectable
2qr2B-6eo5A:
undetectable		 2qr2A-6eo5A:
15.02
2qr2B-6eo5A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B236_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		 6eo5 PPBBE-LIKE 1 D396N
(Physcomitrella
patens) 		4 / 5 GLY A 184
GLY A 185
PHE A 241
PHE A 243
 None
FAD  A 601 (-3.5A)
None
None
 0.75A 2qr2A-6eo5A:
undetectable
2qr2B-6eo5A:
undetectable		 2qr2A-6eo5A:
15.02
2qr2B-6eo5A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QWX_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 6eo5 PPBBE-LIKE 1 D396N
(Physcomitrella
patens) 		4 / 7 GLY A 185
GLY A 231
PHE A 241
PHE A 243
 FAD  A 601 (-3.5A)
None
None
None
 0.80A 2qwxA-6eo5A:
undetectable
2qwxB-6eo5A:
undetectable		 2qwxA-6eo5A:
15.02
2qwxB-6eo5A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX4_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 6eo5 PPBBE-LIKE 1 D396N
(Physcomitrella
patens) 		4 / 8 PHE A 241
PHE A 243
GLY A 184
GLY A 185
 None
None
None
FAD  A 601 (-3.5A)
 0.73A 2qx4A-6eo5A:
undetectable
2qx4B-6eo5A:
undetectable		 2qx4A-6eo5A:
15.02
2qx4B-6eo5A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX6_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 6eo5 PPBBE-LIKE 1 D396N
(Physcomitrella
patens) 		4 / 6 PHE A 241
PHE A 243
GLY A 184
GLY A 185
 None
None
None
FAD  A 601 (-3.5A)
 0.74A 2qx6A-6eo5A:
undetectable
2qx6B-6eo5A:
undetectable		 2qx6A-6eo5A:
15.02
2qx6B-6eo5A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ITA_D_AICD501_1
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACC)		 6eo5 PPBBE-LIKE 1 D396N
(Physcomitrella
patens) 		3 / 3 PRO A 106
PHE A 494
ALA A 232
 FAD  A 601 (-4.0A)
FAD  A 601 ( 4.5A)
FAD  A 601 (-3.3A)
 0.68A 3itaD-6eo5A:
undetectable		 3itaD-6eo5A:
14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_B_ECNB602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 6eo5 PPBBE-LIKE 1 D396N
(Physcomitrella
patens) 		5 / 9 LEU A 195
THR A 197
GLY A 231
ALA A 230
ILE A 415
 None
 1.20A 3jusB-6eo5A:
undetectable		 3jusB-6eo5A:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_H_DHIH3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		 6eo5 PPBBE-LIKE 1 D396N
(Physcomitrella
patens) 		3 / 3 LEU A 311
TRP A 275
GLY A 276
 None
 0.63A 3l35A-6eo5A:
undetectable
3l35H-6eo5A:
undetectable		 3l35A-6eo5A:
undetectable
3l35H-6eo5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_K_DHIK3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		 6eo5 PPBBE-LIKE 1 D396N
(Physcomitrella
patens) 		3 / 3 LEU A 311
TRP A 275
GLY A 276
 None
 0.59A 3l35B-6eo5A:
undetectable
3l35K-6eo5A:
undetectable		 3l35B-6eo5A:
undetectable
3l35K-6eo5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_A_SAMA201_0
(YAEB-LIKE PROTEIN
RPA0152)		 6eo5 PPBBE-LIKE 1 D396N
(Physcomitrella
patens) 		5 / 12 LEU A 118
HIS A 111
LEU A  68
ARG A  67
THR A 357
 None
FAD  A 601 (-2.6A)
None
None
None
 1.14A 3okxA-6eo5A:
undetectable		 3okxA-6eo5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGY_A_GLYA510_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 6eo5 PPBBE-LIKE 1 D396N
(Physcomitrella
patens) 		4 / 6 ILE A 462
GLU A 114
ALA A 363
ASN A  71
 None
 0.99A 3pgyA-6eo5A:
undetectable
3pgyB-6eo5A:
undetectable		 3pgyA-6eo5A:
undetectable
3pgyB-6eo5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGY_A_GLYA510_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 6eo5 PPBBE-LIKE 1 D396N
(Physcomitrella
patens) 		4 / 6 ILE A 462
GLU A 114
PHE A 361
ALA A 363
 None
 1.11A 3pgyA-6eo5A:
undetectable
3pgyB-6eo5A:
undetectable		 3pgyA-6eo5A:
undetectable
3pgyB-6eo5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCB_A_017A201_1
(PROTEASE)		 6eo5 PPBBE-LIKE 1 D396N
(Physcomitrella
patens) 		5 / 12 GLY A 184
ASP A 198
ASN A 199
ILE A 167
GLY A 187
 None
 0.97A 3ucbA-6eo5A:
undetectable		 3ucbA-6eo5A:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMA_D_ADND604_1
(PYRUVATE KINASE)		 6eo5 PPBBE-LIKE 1 D396N
(Physcomitrella
patens) 		3 / 3 ARG A  73
GLU A 114
ASN A  71
 None
 0.80A 4imaD-6eo5A:
undetectable		 4imaD-6eo5A:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IP7_D_ADND604_1
(PYRUVATE KINASE
ISOZYMES L)		 6eo5 PPBBE-LIKE 1 D396N
(Physcomitrella
patens) 		3 / 3 ARG A  73
GLU A 114
ASN A  71
 None
 0.83A 4ip7D-6eo5A:
undetectable		 4ip7D-6eo5A:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_B_LOCB503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 6eo5 PPBBE-LIKE 1 D396N
(Physcomitrella
patens) 		3 / 3 SER A 389
ALA A 427
VAL A 426
 None
 0.57A 4o2bA-6eo5A:
undetectable		 4o2bA-6eo5A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 6eo5 PPBBE-LIKE 1 D396N
(Physcomitrella
patens) 		3 / 3 SER A 389
ALA A 427
VAL A 426
 None
 0.57A 4x1iA-6eo5A:
undetectable		 4x1iA-6eo5A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECO_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 6eo5 PPBBE-LIKE 1 D396N
(Physcomitrella
patens) 		4 / 6 THR A 242
ALA A 144
THR A 143
VAL A 245
 None
 0.89A 5ecoA-6eo5A:
undetectable		 5ecoA-6eo5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESL_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 6eo5 PPBBE-LIKE 1 D396N
(Physcomitrella
patens) 		5 / 12 GLY A 185
PHE A 492
ILE A 104
THR A 239
THR A 197
 FAD  A 601 (-3.5A)
None
None
None
None
 1.30A 5eslA-6eo5A:
undetectable		 5eslA-6eo5A:
10.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EYP_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 6eo5 PPBBE-LIKE 1 D396N
(Physcomitrella
patens) 		3 / 3 SER A 389
ALA A 427
VAL A 426
 None
 0.58A 5eypA-6eo5A:
undetectable		 5eypA-6eo5A:
12.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FA8_A_SAMA301_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE,
PUTATIVE)		 6eo5 PPBBE-LIKE 1 D396N
(Physcomitrella
patens) 		5 / 12 GLY A 187
GLY A 185
ILE A 404
ASN A 339
PHE A 188
 None
FAD  A 601 (-3.5A)
None
None
None
 1.17A 5fa8A-6eo5A:
undetectable		 5fa8A-6eo5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_A_SAMA301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 6eo5 PPBBE-LIKE 1 D396N
(Physcomitrella
patens) 		5 / 12 ALA A  69
ASP A 122
PRO A  78
GLY A 120
SER A 117
 None
None
None
None
FAD  A 601 (-2.6A)
 1.25A 5hfjA-6eo5A:
undetectable		 5hfjA-6eo5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LBT_A_6T0A304_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 6eo5 PPBBE-LIKE 1 D396N
(Physcomitrella
patens) 		5 / 10 GLY A 184
GLY A 185
PHE A 241
ILE A 177
PHE A 243
 None
FAD  A 601 (-3.5A)
None
None
None
 1.25A 5lbtA-6eo5A:
undetectable
5lbtB-6eo5A:
undetectable		 5lbtA-6eo5A:
15.07
5lbtB-6eo5A:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJB_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 6eo5 PPBBE-LIKE 1 D396N
(Physcomitrella
patens) 		5 / 12 PHE A 188
ALA A 285
PHE A 272
TYR A 288
ILE A 394
 None
 1.41A 5ljbA-6eo5A:
undetectable		 5ljbA-6eo5A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUI_B_CTCB405_0
(TETRACYCLINE
DESTRUCTASE TET(50))		 6eo5 PPBBE-LIKE 1 D396N
(Physcomitrella
patens) 		5 / 12 GLY A 184
GLY A 109
GLY A 231
VAL A 203
ILE A 200
 None
FAD  A 601 (-3.1A)
None
None
None
 0.85A 5tuiB-6eo5A:
undetectable		 5tuiB-6eo5A:
undetectable