SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6eoe'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
4 / 6 ASN A 177
PHE A 176
ALA A 179
GLY A 100
None
1.07A 1c8lA-6eoeA:
undetectable
1c8lA-6eoeA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
4 / 6 ASN A 177
PHE A 176
ALA A 179
GLY A 100
None
1.04A 1gfzA-6eoeA:
undetectable
1gfzA-6eoeA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_B_SAMB1293_1
(GLYCINE
N-METHYLTRANSFERASE)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
4 / 5 ARG A 261
ASP A 250
ASN A 248
SER A 337
None
1.29A 1kiaB-6eoeA:
undetectable
1kiaB-6eoeA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_SAMC2293_1
(GLYCINE
N-METHYLTRANSFERASE)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
4 / 6 ARG A 261
ASP A 250
ASN A 248
SER A 337
None
1.31A 1kiaC-6eoeA:
undetectable
1kiaC-6eoeA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
4 / 6 ASN A 177
PHE A 176
ALA A 179
GLY A 100
None
1.04A 1l5qA-6eoeA:
undetectable
1l5qA-6eoeA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
4 / 6 ASN A 177
PHE A 176
ALA A 179
GLY A 100
None
1.03A 1l5qB-6eoeA:
undetectable
1l5qB-6eoeA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
4 / 6 ASN A 177
PHE A 176
ALA A 179
GLY A 100
None
1.00A 1l7xA-6eoeA:
undetectable
1l7xA-6eoeA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
4 / 6 ASN A 177
PHE A 176
ALA A 179
GLY A 100
None
1.03A 1l7xB-6eoeA:
undetectable
1l7xB-6eoeA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_B_SAMB1293_1
(GLYCINE
N-METHYLTRANSFERASE)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
4 / 5 ARG A 261
ASP A 250
ASN A 248
SER A 337
None
1.29A 1nbhB-6eoeA:
0.9
1nbhB-6eoeA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RE7_B_FOLB361_0
(DIHYDROFOLATE
REDUCTASE)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
5 / 12 ILE A 426
LEU A 509
PHE A 501
ILE A 526
ILE A 463
None
1.19A 1re7B-6eoeA:
undetectable
1re7B-6eoeA:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_B_SAMB802_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
5 / 12 ILE A 371
GLY A 254
GLY A 227
LEU A 334
LEU A 253
None
None
ADP  A 603 ( 2.9A)
None
None
1.10A 1rjdB-6eoeA:
undetectable
1rjdB-6eoeA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
5 / 12 ILE A 371
GLY A 254
GLY A 227
LEU A 334
LEU A 253
None
None
ADP  A 603 ( 2.9A)
None
None
1.09A 1rjdC-6eoeA:
undetectable
1rjdC-6eoeA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HJH_A_NCAA900_0
(NAD-DEPENDENT
HISTONE DEACETYLASE
SIR2)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
4 / 5 ILE A  76
PHE A  68
PHE A 548
ILE A 145
None
0.99A 2hjhA-6eoeA:
undetectable
2hjhA-6eoeA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6O_B_SAMB500_0
(HYPOTHETICAL PROTEIN)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
4 / 6 ASP A 224
VAL A 362
PRO A 173
THR A 171
None
None
SO4  A 602 ( 4.3A)
None
1.43A 2q6oB-6eoeA:
undetectable
2q6oB-6eoeA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BCR_A_AZZA940_1
(GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
4 / 5 ASN A 177
PHE A 176
ALA A 179
GLY A 100
None
1.09A 3bcrA-6eoeA:
undetectable
3bcrA-6eoeA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYW_A_017A201_1
(HIV-1 PROTEASE)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
5 / 12 LEU A  35
ASP A 391
VAL A 394
GLY A 226
PRO A 173
None
ADP  A 603 (-3.6A)
None
SO4  A 602 ( 3.4A)
SO4  A 602 ( 4.3A)
0.87A 3cywA-6eoeA:
undetectable
3cywA-6eoeA:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
4 / 6 ASN A 177
PHE A 176
ALA A 179
GLY A 100
None
1.06A 3dd1A-6eoeA:
undetectable
3dd1A-6eoeA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
4 / 6 ASN A 177
PHE A 176
ALA A 179
GLY A 100
None
1.03A 3dd1B-6eoeA:
undetectable
3dd1B-6eoeA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
4 / 6 ASN A 177
PHE A 176
ALA A 179
GLY A 100
None
1.04A 3ddsA-6eoeA:
undetectable
3ddsA-6eoeA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
4 / 6 ASN A 177
PHE A 176
ALA A 179
GLY A 100
None
1.03A 3ddsB-6eoeA:
undetectable
3ddsB-6eoeA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
4 / 6 ASN A 177
PHE A 176
ALA A 179
GLY A 100
None
1.06A 3ddwA-6eoeA:
undetectable
3ddwA-6eoeA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
4 / 6 ASN A 177
PHE A 176
ALA A 179
GLY A 100
None
1.04A 3ddwB-6eoeA:
undetectable
3ddwB-6eoeA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B302_2
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
3 / 3 CYH A  41
PRO A  63
ASP A 391
None
None
ADP  A 603 (-3.6A)
0.92A 3hlwB-6eoeA:
undetectable
3hlwB-6eoeA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU5_B_478B401_2
(PROTEASE)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
5 / 12 GLY A 397
ALA A 398
GLY A 403
VAL A 404
ILE A 199
None
None
None
FLC  A 601 (-4.7A)
None
1.14A 3nu5B-6eoeA:
undetectable
3nu5B-6eoeA:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_A_DR7A100_1
(HIV-1 PROTEASE)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
5 / 12 LEU A  35
ASP A 391
VAL A 394
GLY A 226
PRO A 173
None
ADP  A 603 (-3.6A)
None
SO4  A 602 ( 3.4A)
SO4  A 602 ( 4.3A)
0.89A 3oxxA-6eoeA:
undetectable
3oxxA-6eoeA:
12.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_B_TPVB100_2
(HIV-1 PROTEASE)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
5 / 12 LEU A  35
ASP A 391
VAL A 394
GLY A 226
PRO A 173
None
ADP  A 603 (-3.6A)
None
SO4  A 602 ( 3.4A)
SO4  A 602 ( 4.3A)
0.99A 3spkB-6eoeA:
undetectable
3spkB-6eoeA:
11.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD507_1
(HEMOLYTIC LECTIN
CEL-III)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
4 / 5 ASP A 257
GLU A 256
GLY A 228
ASP A 250
None
None
SO4  A 602 (-3.4A)
None
1.34A 3w9tD-6eoeA:
undetectable
3w9tD-6eoeA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_I_ACTI504_0
(RNA POLYMERASE
3D-POL)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
3 / 3 VAL A  66
GLY A  77
LYS A  81
None
0.77A 4k50I-6eoeA:
undetectable
4k50I-6eoeA:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NC3_A_ERMA1202_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
5 / 12 ASP A  78
VAL A  66
MET A 153
ALA A  54
LEU A  35
None
1.16A 4nc3A-6eoeA:
undetectable
4nc3A-6eoeA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_A_TPVA500_1
(PROTEASE)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
5 / 12 LEU A  35
ASP A 391
VAL A 394
GLY A 226
PRO A 173
None
ADP  A 603 (-3.6A)
None
SO4  A 602 ( 3.4A)
SO4  A 602 ( 4.3A)
0.91A 4njuA-6eoeA:
undetectable
4njuA-6eoeA:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_C_TPVC500_1
(PROTEASE)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
5 / 12 LEU A  35
ASP A 391
VAL A 394
GLY A 226
PRO A 173
None
ADP  A 603 (-3.6A)
None
SO4  A 602 ( 3.4A)
SO4  A 602 ( 4.3A)
0.90A 4njuC-6eoeA:
undetectable
4njuC-6eoeA:
11.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAE_A_CLMA208_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
4 / 4 ALA A 395
ALA A 398
ALA A 399
ALA A 402
None
0.12A 4oaeA-6eoeA:
undetectable
4oaeA-6eoeA:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_B_SAMB601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
5 / 12 ALA A 229
GLY A 228
GLY A 227
ASP A  94
GLY A 249
SO4  A 602 (-3.5A)
SO4  A 602 (-3.4A)
ADP  A 603 ( 2.9A)
None
None
1.01A 4obwB-6eoeA:
undetectable
4obwB-6eoeA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_C_SAMC601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
5 / 12 GLY A 216
ILE A 220
ASN A 219
GLY A 210
PHE A 242
None
1.20A 4obwC-6eoeA:
undetectable
4obwC-6eoeA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_D_SAMD601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
5 / 12 GLY A 216
ILE A 220
ASN A 219
GLY A 210
PHE A 242
None
1.22A 4obwD-6eoeA:
undetectable
4obwD-6eoeA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM5_A_CE3A301_2
(BETA-LACTAMASE
CTX-M-14)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
3 / 3 CYH A  41
PRO A  63
ASP A 391
None
None
ADP  A 603 (-3.6A)
0.89A 4pm5A-6eoeA:
undetectable
4pm5A-6eoeA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB307_1
(CHITOSANASE)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
4 / 7 GLU A 201
THR A  37
GLY A  36
THR A  38
SO4  A 602 (-2.9A)
SO4  A 602 ( 3.9A)
ADP  A 603 ( 3.1A)
ADP  A 603 (-2.9A)
0.92A 4qwpB-6eoeA:
undetectable
4qwpB-6eoeA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_B_RTZB602_1
(CYTOCHROME P450 2D6)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
5 / 12 LEU A 221
GLY A 363
LEU A 225
VAL A 342
PHE A 230
None
ADP  A 603 (-3.6A)
None
None
None
1.07A 4wnwB-6eoeA:
undetectable
4wnwB-6eoeA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4G_A_IPHA903_0
(PROTEIN ARGONAUTE-2)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
4 / 6 LEU A  98
LYS A 125
PRO A 126
GLU A 143
None
1.28A 4z4gA-6eoeA:
2.7
4z4gA-6eoeA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZGF_A_BEZA210_0
(UNCHARACTERIZED
PROTEIN)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
4 / 4 VAL A  66
ALA A  67
ASN A  90
GLN A  83
None
1.42A 4zgfA-6eoeA:
undetectable
4zgfA-6eoeA:
14.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AQF_A_ADNA1382_1
(HEAT SHOCK COGNATE
71 KDA PROTEIN)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
6 / 10 GLY A 226
GLY A 254
GLU A 256
GLY A 364
SER A 365
ILE A 368
SO4  A 602 ( 3.4A)
None
None
ADP  A 603 (-3.1A)
ADP  A 603 (-3.6A)
ADP  A 603 (-4.8A)
1.42A 5aqfA-6eoeA:
47.8
5aqfA-6eoeA:
68.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AQF_A_ADNA1382_1
(HEAT SHOCK COGNATE
71 KDA PROTEIN)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
7 / 10 GLY A 226
LYS A 296
SER A 300
GLY A 364
SER A 365
ARG A 367
ILE A 368
SO4  A 602 ( 3.4A)
ADP  A 603 (-2.7A)
ADP  A 603 (-2.7A)
ADP  A 603 (-3.1A)
ADP  A 603 (-3.6A)
ADP  A 603 (-4.4A)
ADP  A 603 (-4.8A)
1.00A 5aqfA-6eoeA:
47.8
5aqfA-6eoeA:
68.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AQF_A_ADNA1382_1
(HEAT SHOCK COGNATE
71 KDA PROTEIN)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
10 / 10 GLY A 227
GLY A 255
GLU A 293
LYS A 296
ARG A 297
SER A 300
GLY A 364
SER A 365
ARG A 367
ILE A 368
ADP  A 603 ( 2.9A)
ADP  A 603 (-3.4A)
ADP  A 603 (-2.6A)
ADP  A 603 (-2.7A)
ADP  A 603 (-3.4A)
ADP  A 603 (-2.7A)
ADP  A 603 (-3.1A)
ADP  A 603 (-3.6A)
ADP  A 603 (-4.4A)
ADP  A 603 (-4.8A)
0.65A 5aqfA-6eoeA:
47.8
5aqfA-6eoeA:
68.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AQF_A_ADNA1382_1
(HEAT SHOCK COGNATE
71 KDA PROTEIN)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
5 / 10 GLY A 227
GLY A 255
GLY A 364
SER A 365
ILE A 371
ADP  A 603 ( 2.9A)
ADP  A 603 (-3.4A)
ADP  A 603 (-3.1A)
ADP  A 603 (-3.6A)
None
1.03A 5aqfA-6eoeA:
47.8
5aqfA-6eoeA:
68.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AQF_A_ADNA1382_1
(HEAT SHOCK COGNATE
71 KDA PROTEIN)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
6 / 10 GLY A 254
GLY A 255
LYS A 296
SER A 300
SER A 365
ILE A 368
None
ADP  A 603 (-3.4A)
ADP  A 603 (-2.7A)
ADP  A 603 (-2.7A)
ADP  A 603 (-3.6A)
ADP  A 603 (-4.8A)
1.42A 5aqfA-6eoeA:
47.8
5aqfA-6eoeA:
68.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AQF_C_ADNC1382_1
(HEAT SHOCK COGNATE
71 KDA PROTEIN)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
6 / 10 GLY A 226
GLY A 254
GLU A 256
GLY A 364
SER A 365
ILE A 368
SO4  A 602 ( 3.4A)
None
None
ADP  A 603 (-3.1A)
ADP  A 603 (-3.6A)
ADP  A 603 (-4.8A)
1.44A 5aqfC-6eoeA:
47.8
5aqfC-6eoeA:
68.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AQF_C_ADNC1382_1
(HEAT SHOCK COGNATE
71 KDA PROTEIN)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
9 / 10 GLY A 226
GLY A 255
LYS A 296
ARG A 297
SER A 300
GLY A 364
SER A 365
ARG A 367
ILE A 368
SO4  A 602 ( 3.4A)
ADP  A 603 (-3.4A)
ADP  A 603 (-2.7A)
ADP  A 603 (-3.4A)
ADP  A 603 (-2.7A)
ADP  A 603 (-3.1A)
ADP  A 603 (-3.6A)
ADP  A 603 (-4.4A)
ADP  A 603 (-4.8A)
1.08A 5aqfC-6eoeA:
47.8
5aqfC-6eoeA:
68.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AQF_C_ADNC1382_1
(HEAT SHOCK COGNATE
71 KDA PROTEIN)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
10 / 10 GLY A 227
GLY A 255
GLU A 293
LYS A 296
ARG A 297
SER A 300
GLY A 364
SER A 365
ARG A 367
ILE A 368
ADP  A 603 ( 2.9A)
ADP  A 603 (-3.4A)
ADP  A 603 (-2.6A)
ADP  A 603 (-2.7A)
ADP  A 603 (-3.4A)
ADP  A 603 (-2.7A)
ADP  A 603 (-3.1A)
ADP  A 603 (-3.6A)
ADP  A 603 (-4.4A)
ADP  A 603 (-4.8A)
0.67A 5aqfC-6eoeA:
47.8
5aqfC-6eoeA:
68.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AQF_C_ADNC1382_1
(HEAT SHOCK COGNATE
71 KDA PROTEIN)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
5 / 10 GLY A 227
GLY A 255
GLY A 364
SER A 365
ILE A 371
ADP  A 603 ( 2.9A)
ADP  A 603 (-3.4A)
ADP  A 603 (-3.1A)
ADP  A 603 (-3.6A)
None
1.02A 5aqfC-6eoeA:
47.8
5aqfC-6eoeA:
68.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AQF_C_ADNC1382_1
(HEAT SHOCK COGNATE
71 KDA PROTEIN)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
6 / 10 GLY A 254
GLY A 255
LYS A 296
SER A 300
SER A 365
ILE A 368
None
ADP  A 603 (-3.4A)
ADP  A 603 (-2.7A)
ADP  A 603 (-2.7A)
ADP  A 603 (-3.6A)
ADP  A 603 (-4.8A)
1.41A 5aqfC-6eoeA:
47.8
5aqfC-6eoeA:
68.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AQY_A_ADNA1389_1
(HEAT SHOCK 70 KDA
PROTEIN 1A)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
6 / 10 GLY A 226
GLY A 254
GLU A 256
GLY A 364
SER A 365
ILE A 368
SO4  A 602 ( 3.4A)
None
None
ADP  A 603 (-3.1A)
ADP  A 603 (-3.6A)
ADP  A 603 (-4.8A)
1.38A 5aqyA-6eoeA:
50.5
5aqyA-6eoeA:
52.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AQY_A_ADNA1389_1
(HEAT SHOCK 70 KDA
PROTEIN 1A)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
9 / 10 GLY A 226
GLY A 255
LYS A 296
ARG A 297
SER A 300
GLY A 364
SER A 365
ARG A 367
ILE A 368
SO4  A 602 ( 3.4A)
ADP  A 603 (-3.4A)
ADP  A 603 (-2.7A)
ADP  A 603 (-3.4A)
ADP  A 603 (-2.7A)
ADP  A 603 (-3.1A)
ADP  A 603 (-3.6A)
ADP  A 603 (-4.4A)
ADP  A 603 (-4.8A)
1.02A 5aqyA-6eoeA:
50.5
5aqyA-6eoeA:
52.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AQY_A_ADNA1389_1
(HEAT SHOCK 70 KDA
PROTEIN 1A)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
10 / 10 GLY A 227
GLY A 255
GLU A 293
LYS A 296
ARG A 297
SER A 300
GLY A 364
SER A 365
ARG A 367
ILE A 368
ADP  A 603 ( 2.9A)
ADP  A 603 (-3.4A)
ADP  A 603 (-2.6A)
ADP  A 603 (-2.7A)
ADP  A 603 (-3.4A)
ADP  A 603 (-2.7A)
ADP  A 603 (-3.1A)
ADP  A 603 (-3.6A)
ADP  A 603 (-4.4A)
ADP  A 603 (-4.8A)
0.61A 5aqyA-6eoeA:
50.5
5aqyA-6eoeA:
52.82
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5AQY_A_ADNA1389_1
(HEAT SHOCK 70 KDA
PROTEIN 1A)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
6 / 10 GLY A 254
GLY A 255
LYS A 296
SER A 300
SER A 365
ILE A 368
None
ADP  A 603 (-3.4A)
ADP  A 603 (-2.7A)
ADP  A 603 (-2.7A)
ADP  A 603 (-3.6A)
ADP  A 603 (-4.8A)
1.44A 5aqyA-6eoeA:
50.5
5aqyA-6eoeA:
52.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_A_SAMA301_1
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
3 / 3 GLY A 407
ASP A 408
ASN A  47
None
0.63A 5jglA-6eoeA:
undetectable
5jglA-6eoeA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_1
(SULFOTRANSFERASE)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
4 / 4 TYR A  39
ASP A 391
ASP A 259
SER A 365
ADP  A 603 (-4.9A)
ADP  A 603 (-3.6A)
None
ADP  A 603 (-3.6A)
1.31A 5tiwA-6eoeA:
0.0
5tiwA-6eoeA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UTU_H_ADNH503_2
(ADENOSYLHOMOCYSTEINA
SE)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
4 / 5 THR A 512
GLU A 502
THR A 445
LEU A 424
None
1.31A 5utuH-6eoeA:
2.4
5utuH-6eoeA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X24_A_LSNA502_1
(CYTOCHROME P450 2C9)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
5 / 12 ALA A 204
VAL A 400
VAL A  50
GLY A  43
THR A 156
None
1.21A 5x24A-6eoeA:
undetectable
5x24A-6eoeA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BM5_A_SAMA1301_0
(METHIONINE SYNTHASE)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
5 / 11 PRO A 106
PRO A 421
PRO A 173
ALA A 174
TYR A 175
None
None
SO4  A 602 ( 4.3A)
None
None
1.33A 6bm5A-6eoeA:
undetectable
6bm5A-6eoeA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIL_B_TPVB201_0
(HIV-1 PROTEASE)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
5 / 12 LEU A  35
ASP A 391
VAL A 394
GLY A 226
PRO A 173
None
ADP  A 603 (-3.6A)
None
SO4  A 602 ( 3.4A)
SO4  A 602 ( 4.3A)
0.89A 6dilA-6eoeA:
undetectable
6dilA-6eoeA:
12.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_3
(-)
6eoe 78 KDA
GLUCOSE-REGULATED
PROTEIN

(Cricetulus
griseus)
3 / 3 ASP A 257
ASP A 231
ASN A 440
None
0.83A 6gngB-6eoeA:
undetectable
6gngB-6eoeA:
21.08