SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6eoj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
13GS_A_SASA211_1
(GLUTATHIONE
S-TRANSFERASE)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		5 / 10 TYR A 871
PRO A 870
VAL A 869
ILE A1344
GLY A 843
 None
 1.44A 13gsA-6eojA:
undetectable		 13gsA-6eojA:
10.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB8_0
(ACTINOMYCIN D)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		3 / 3 THR A1086
THR A1051
PRO A1050
 None
 0.86A 1a7yB-6eojA:
undetectable		 1a7yB-6eojA:
1.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AQB_A_RTLA185_0
(RETINOL-BINDING
PROTEIN)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		5 / 10 LEU A 873
ALA A 839
VAL A 865
LEU A 802
PHE A1348
 None
 1.27A 1aqbA-6eojA:
undetectable		 1aqbA-6eojA:
8.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA350_2
(PROTEIN (ADENOSINE
KINASE))		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		3 / 3 LEU A  48
SER A 504
ASN A 507
 None
 0.76A 1bx4A-6eojA:
undetectable		 1bx4A-6eojA:
13.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DLS_A_MTXA188_1
(DIHYDROFOLATE
REDUCTASE)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		5 / 12 ALA A 831
PHE A 884
GLN A 555
SER A 879
LEU A 929
 None
 1.21A 1dlsA-6eojA:
undetectable		 1dlsA-6eojA:
8.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4002_1
(SERUM ALBUMIN)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		4 / 6 LEU A   8
VAL A 508
VAL A 553
GLN A 555
 None
 1.07A 1e7aB-6eojA:
undetectable		 1e7aB-6eojA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IG3_B_VIBB501_1
(THIAMIN
PYROPHOSPHOKINASE)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		4 / 7 GLN A 990
LEU A 969
SER A1013
ASN A1012
 None
 0.90A 1ig3A-6eojA:
undetectable
1ig3B-6eojA:
undetectable		 1ig3A-6eojA:
11.84
1ig3B-6eojA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MCN_P_DHIP1_0
(IMMUNOGLOBULIN
LAMBDA DIMER MCG
(LIGHT CHAIN)
PEPTIDE
N-ACETYL-D-HIS-L-PRO
-NH2)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		3 / 3 PHE A 884
TYR A 922
PRO A 928
 None
 1.14A 1mcnA-6eojA:
undetectable
1mcnB-6eojA:
undetectable
1mcnP-6eojA:
undetectable		 1mcnA-6eojA:
11.18
1mcnB-6eojA:
11.18
1mcnP-6eojA:
40.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_A_SAMA293_1
(GLYCINE
N-METHYLTRANSFERASE)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		4 / 5 ARG A  41
ASP A 421
ASN A 437
TYR A  49
 None
 1.49A 1nbiA-6eojA:
2.1		 1nbiA-6eojA:
12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_B_SAMB1293_1
(GLYCINE
N-METHYLTRANSFERASE)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		4 / 5 ARG A  41
ASP A 421
ASN A 437
TYR A  49
 None
 1.49A 1nbiB-6eojA:
undetectable		 1nbiB-6eojA:
12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		4 / 8 SER A 310
ASN A 329
GLN A 376
PHE A 387
 None
 1.33A 1p6kA-6eojA:
undetectable		 1p6kA-6eojA:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_A_DEXA1999_1
(GLUCOCORTICOID
RECEPTOR)		 6eoj POLYADENYLATION
FACTOR SUBUNIT
2,POLYADENYLATION
FACTOR SUBUNIT 2
(Saccharomyces
cerevisiae) 		5 / 12 MET D 295
LEU D 276
GLN D 270
MET D 231
ILE D 257
 None
 1.21A 1p93A-6eojD:
undetectable		 1p93A-6eojD:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		4 / 8 SER A 310
ASN A 329
GLN A 376
PHE A 387
 None
 1.32A 1rs6A-6eojA:
undetectable		 1rs6A-6eojA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S1U_A_NVPA999_1
(REVERSE
TRANSCRIPTASE)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		5 / 10 ILE A1036
VAL A1015
VAL A1090
GLY A1039
TYR A1057
 None
 1.28A 1s1uA-6eojA:
undetectable		 1s1uA-6eojA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDT_B_MK1B902_1
(PROTEASE RETROPEPSIN)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		5 / 10 ARG A 506
LEU A 929
GLY A1248
GLY A1249
ILE A 554
 None
 0.81A 1sdtA-6eojA:
undetectable		 1sdtA-6eojA:
6.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDV_B_MK1B902_1
(PROTEASE RETROPEPSIN)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		5 / 10 ARG A 506
LEU A 929
GLY A1248
GLY A1249
ILE A 554
 None
 0.82A 1sdvA-6eojA:
undetectable		 1sdvA-6eojA:
6.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U72_A_MTXA188_1
(DIHYDROFOLATE
REDUCTASE)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		5 / 12 ALA A 831
PHE A 884
GLN A 555
SER A 879
LEU A 929
 None
 1.29A 1u72A-6eojA:
undetectable		 1u72A-6eojA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_A_SAMA3142_1
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 792
ASP A  45
ASN A 412
ASP A 877
 None
 1.50A 1wg8A-6eojA:
undetectable		 1wg8A-6eojA:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_A_IMNA379_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		5 / 12 TYR A 798
THR A 800
PRO A 881
ILE A 863
VAL A 785
 None
 1.43A 1z9hA-6eojA:
undetectable		 1z9hA-6eojA:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_B_IMNB381_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		5 / 12 TYR A 798
THR A 800
PRO A 881
ILE A 863
VAL A 785
 None
 1.42A 1z9hB-6eojA:
undetectable		 1z9hB-6eojA:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_C_IMNC379_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		5 / 12 TYR A 798
THR A 800
PRO A 881
ILE A 863
VAL A 785
 None
 1.43A 1z9hC-6eojA:
undetectable		 1z9hC-6eojA:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		4 / 8 SER A 310
ASN A 329
GLN A 376
PHE A 387
 None
 1.33A 1zzqA-6eojA:
undetectable		 1zzqA-6eojA:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC8_0
(N8-ACTINOMYCIN D)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		3 / 3 THR A1086
THR A1051
PRO A1050
 None
 0.88A 209dC-6eojA:
undetectable		 209dC-6eojA:
1.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AB2_A_SNLA502_2
(MINERALOCORTICOID
RECEPTOR)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		4 / 6 LEU A  17
LEU A  30
LEU A  78
LEU A 123
 None
 0.98A 2ab2A-6eojA:
undetectable		 2ab2A-6eojA:
11.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_1
(POL POLYPROTEIN)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		5 / 12 ARG A 506
LEU A 929
GLY A1248
GLY A1249
ILE A 554
 None
 0.79A 2avvA-6eojA:
undetectable		 2avvA-6eojA:
6.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2003_1
(SERUM ALBUMIN)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		5 / 9 LEU A 392
PHE A 497
LEU A 364
ARG A 410
LEU A 422
 None
 1.29A 2bxeA-6eojA:
undetectable		 2bxeA-6eojA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYO_A_LNLA1217_1
(LIPOPROTEIN LPPX)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		4 / 4 VAL A 294
LEU A 399
ILE A 394
LEU A 392
 None
 1.00A 2byoA-6eojA:
undetectable		 2byoA-6eojA:
9.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DQY_B_CHDB2_0
(LIVER
CARBOXYLESTERASE 1)		 6eoj POLYADENYLATION
FACTOR SUBUNIT
2,POLYADENYLATION
FACTOR SUBUNIT 2
(Saccharomyces
cerevisiae) 		3 / 3 TRP D 312
LYS D 142
PRO D 271
 None
 1.21A 2dqyB-6eojD:
undetectable		 2dqyB-6eojD:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FT9_A_CHDA131_0
(FATTY ACID-BINDING
PROTEIN 2, LIVER)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		5 / 11 LEU A  78
LEU A  76
THR A 826
ASN A 824
LEU A 102
 None
 1.34A 2ft9A-6eojA:
undetectable		 2ft9A-6eojA:
6.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HYY_B_STIB600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		4 / 6 VAL A 869
VAL A 558
ILE A 883
MET A 921
 None
 1.21A 2hyyB-6eojA:
undetectable		 2hyyB-6eojA:
11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IWK_A_CUA1599_0
(NITROUS OXIDE
REDUCTASE)		 6eoj MRNA
3'-END-PROCESSING
PROTEIN YTH1
(Saccharomyces
cerevisiae) 		3 / 3 CYH B  46
CYH B  52
HIS B  56
 ZN  B 302 ( 2.3A)
ZN  B 302 ( 2.3A)
ZN  B 302 ( 3.2A)
 0.88A 2iwkA-6eojB:
undetectable		 2iwkA-6eojB:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IWK_A_CUA1599_0
(NITROUS OXIDE
REDUCTASE)		 6eoj MRNA
3'-END-PROCESSING
PROTEIN YTH1
(Saccharomyces
cerevisiae) 		3 / 3 CYH B  75
CYH B  81
HIS B  85
 ZN  B 301 ( 2.3A)
ZN  B 301 ( 2.3A)
ZN  B 301 ( 3.2A)
 0.88A 2iwkA-6eojB:
undetectable		 2iwkA-6eojB:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IWK_B_CUB1599_0
(NITROUS OXIDE
REDUCTASE)		 6eoj MRNA
3'-END-PROCESSING
PROTEIN YTH1
(Saccharomyces
cerevisiae) 		3 / 3 CYH B  46
CYH B  52
HIS B  56
 ZN  B 302 ( 2.3A)
ZN  B 302 ( 2.3A)
ZN  B 302 ( 3.2A)
 0.86A 2iwkB-6eojB:
undetectable		 2iwkB-6eojB:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IWK_B_CUB1599_0
(NITROUS OXIDE
REDUCTASE)		 6eoj MRNA
3'-END-PROCESSING
PROTEIN YTH1
(Saccharomyces
cerevisiae) 		3 / 3 CYH B  75
CYH B  81
HIS B  85
 ZN  B 301 ( 2.3A)
ZN  B 301 ( 2.3A)
ZN  B 301 ( 3.2A)
 0.85A 2iwkB-6eojB:
undetectable		 2iwkB-6eojB:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J0D_A_ERYA1498_0
(CYTOCHROME P450 3A4)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		5 / 12 PHE A1348
ARG A 849
SER A 781
ILE A 782
ALA A 839
 None
 1.17A 2j0dA-6eojA:
undetectable		 2j0dA-6eojA:
17.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_2
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		4 / 6 ARG A  41
ASN A 412
ASN A 430
LEU A 501
 None
 1.30A 2nyrA-6eojA:
undetectable		 2nyrA-6eojA:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OD9_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		3 / 3 PHE A  21
PHE A  54
PHE A  56
 None
 0.82A 2od9A-6eojA:
undetectable		 2od9A-6eojA:
11.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OPX_A_DXCA1001_0
(ALDEHYDE
DEHYDROGENASE A)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		4 / 7 LEU A 365
PHE A 390
ILE A 292
PHE A 387
 None
 0.92A 2opxA-6eojA:
undetectable		 2opxA-6eojA:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6H_A_CXXA802_1
(TRANSPORTER)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		4 / 7 ILE A 709
SER A 662
PHE A 734
PHE A 744
 None
 1.11A 2q6hA-6eojA:
undetectable		 2q6hA-6eojA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA802_1
(TRANSPORTER)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		4 / 7 ILE A 709
SER A 662
PHE A 734
PHE A 744
 None
 1.11A 2qb4A-6eojA:
undetectable		 2qb4A-6eojA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA507_0
(CHORISMATE SYNTHASE)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		3 / 3 LEU A 505
ASN A 507
ARG A  33
 None
 0.94A 2qhfA-6eojA:
undetectable		 2qhfA-6eojA:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQG_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		3 / 3 PHE A  21
PHE A  54
PHE A  56
 None
 0.82A 2qqgA-6eojA:
undetectable		 2qqgA-6eojA:
11.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VN1_A_FK5A501_2
(70 KDA
PEPTIDYLPROLYL
ISOMERASE)		 6eoj POLYADENYLATION
FACTOR SUBUNIT
2,POLYADENYLATION
FACTOR SUBUNIT 2
(Saccharomyces
cerevisiae) 		4 / 6 SER D 285
PHE D 260
ASP D 283
GLU D 297
 None
 1.28A 2vn1B-6eojD:
undetectable		 2vn1B-6eojD:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3M_A_FOLA1188_0
(DIHYDROFOLATE
REDUCTASE)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		5 / 12 ALA A 300
LEU A 277
GLN A 217
ILE A 252
LEU A 219
 None
 1.06A 2w3mA-6eojA:
undetectable		 2w3mA-6eojA:
8.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		5 / 10 ILE A 216
PHE A 142
TYR A 231
LEU A 253
LEU A 255
 None
 1.31A 2w98A-6eojA:
undetectable		 2w98A-6eojA:
13.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGO_A_PCFA1213_0
(WNT INHIBITORY
FACTOR 1)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 755
ILE A 801
ILE A 782
ILE A 741
ILE A 863
 None
 0.96A 2ygoA-6eojA:
undetectable		 2ygoA-6eojA:
8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_C_2FAC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 6eoj POLYADENYLATION
FACTOR SUBUNIT
2,POLYADENYLATION
FACTOR SUBUNIT 2
PROTEIN CFT1
(Saccharomyces
cerevisiae) 		4 / 5 LEU A 944
GLN A 931
THR A 512
HIS D  48
 None
 1.34A 2zj0C-6eojA:
undetectable		 2zj0C-6eojA:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZM_A_SAMA401_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		3 / 3 ARG A 827
ASP A1309
ASN A  35
 None
 0.83A 2zzmA-6eojA:
undetectable		 2zzmA-6eojA:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
316D_C_DVAC2_0
(8-FLUORO-ACTINOMYCIN
D)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		3 / 3 THR A1051
PRO A1050
THR A1086
 None
 0.89A 316dC-6eojA:
undetectable		 316dC-6eojA:
1.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APV_B_TP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		5 / 12 PHE A 654
VAL A 658
PHE A 734
PHE A 744
LEU A 699
 None
 1.37A 3apvB-6eojA:
undetectable		 3apvB-6eojA:
9.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CSJ_B_CBLB211_0
(GLUTATHIONE
S-TRANSFERASE P)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		5 / 9 TYR A 871
PRO A 870
VAL A 869
ILE A1344
GLY A 843
 None
 1.44A 3csjB-6eojA:
undetectable		 3csjB-6eojA:
10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_4
(HIV-1 PROTEASE)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		4 / 4 LEU A 927
ASP A 878
VAL A 508
THR A 552
 None
 1.25A 3cyxB-6eojA:
undetectable		 3cyxB-6eojA:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_D_ROFD904_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 6eoj POLYADENYLATION
FACTOR SUBUNIT
2,POLYADENYLATION
FACTOR SUBUNIT 2
(Saccharomyces
cerevisiae) 		3 / 3 ASN D 339
MET D 278
PHE D 332
 None
 0.84A 3g4lD-6eojD:
undetectable		 3g4lD-6eojD:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_A_EPAA1_2
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		5 / 12 THR A 826
LEU A1286
ILE A  60
HIS A1221
TYR A   4
 None
 1.32A 3gwxA-6eojA:
undetectable		 3gwxA-6eojA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HAV_A_SRYA403_1
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		4 / 8 ASP A 590
SER A 594
ASP A 616
TYR A 599
 None
 1.25A 3havA-6eojA:
2.3		 3havA-6eojA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I45_A_NIOA500_1
(TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN)		 6eoj MRNA
3'-END-PROCESSING
PROTEIN YTH1
PROTEIN CFT1
(Saccharomyces
cerevisiae) 		4 / 8 LEU A1162
TYR A1199
PHE B  15
LEU B  19
 None
 0.94A 3i45A-6eojA:
undetectable		 3i45A-6eojA:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K5V_A_STIA2_2
(TYROSINE-PROTEIN
KINASE ABL1)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		4 / 6 VAL A 869
VAL A 558
ILE A 883
MET A 921
 None
 1.23A 3k5vA-6eojA:
undetectable		 3k5vA-6eojA:
11.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K5V_B_STIB2_2
(TYROSINE-PROTEIN
KINASE ABL1)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		4 / 6 VAL A 869
VAL A 558
ILE A 883
MET A 921
 None
 1.25A 3k5vB-6eojA:
undetectable		 3k5vB-6eojA:
11.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSF_H_PZIH800_0
(GLUTAMATE RECEPTOR 2)		 6eoj MRNA
3'-END-PROCESSING
PROTEIN YTH1
(Saccharomyces
cerevisiae) 		4 / 8 PRO B  17
SER B  26
LEU B  27
ASP B  28
 None
 1.09A 3lsfH-6eojB:
undetectable		 3lsfH-6eojB:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MS9_B_STIB1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		4 / 7 VAL A 869
VAL A 558
ILE A 883
MET A 921
 None
 1.23A 3ms9B-6eojA:
undetectable		 3ms9B-6eojA:
11.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_A_SAMA201_0
(YAEB-LIKE PROTEIN
RPA0152)		 6eoj POLYADENYLATION
FACTOR SUBUNIT
2,POLYADENYLATION
FACTOR SUBUNIT 2
(Saccharomyces
cerevisiae) 		5 / 12 LEU D 233
PRO D 248
GLY D 251
CYH D 253
LEU D 245
 None
 1.37A 3okxA-6eojD:
undetectable		 3okxA-6eojD:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OWX_A_XRAA233_2
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		5 / 5 VAL A 672
PHE A 734
ILE A 679
PHE A 732
PHE A 744
 None
 1.46A 3owxB-6eojA:
undetectable		 3owxB-6eojA:
9.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PRS_A_RITA1001_1
(ENDOTHIAPEPSIN)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		5 / 10 ASP A 779
LEU A 765
ILE A 863
THR A 803
ILE A 883
 None
 1.05A 3prsA-6eojA:
undetectable		 3prsA-6eojA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RET_A_SALA201_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		5 / 10 VAL A1090
ARG A1108
VAL A1116
ILE A1023
ILE A1099
 None
 1.42A 3retA-6eojA:
undetectable
3retB-6eojA:
undetectable		 3retA-6eojA:
5.45
3retB-6eojA:
5.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RFA_A_SAMA406_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE N)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		5 / 12 PHE A 864
GLU A 563
SER A 901
VAL A 862
ILE A 874
 None
 1.45A 3rfaA-6eojA:
undetectable		 3rfaA-6eojA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S43_A_478A401_1
(PROTEASE)		 6eoj POLYADENYLATION
FACTOR SUBUNIT
2,POLYADENYLATION
FACTOR SUBUNIT 2
(Saccharomyces
cerevisiae) 		5 / 9 ALA D 175
ILE D 180
ILE D 203
ILE D 151
ILE D 159
 None
 0.88A 3s43A-6eojD:
undetectable		 3s43A-6eojD:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S45_B_478B201_1
(PROTEASE)		 6eoj POLYADENYLATION
FACTOR SUBUNIT
2,POLYADENYLATION
FACTOR SUBUNIT 2
(Saccharomyces
cerevisiae) 		5 / 9 ALA D 175
ILE D 180
ILE D 203
ILE D 151
ILE D 159
 None
 0.95A 3s45A-6eojD:
undetectable		 3s45A-6eojD:
12.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S53_A_017A201_2
(PROTEASE)		 6eoj POLYADENYLATION
FACTOR SUBUNIT
2,POLYADENYLATION
FACTOR SUBUNIT 2
(Saccharomyces
cerevisiae) 		5 / 11 ALA D 175
ILE D 180
ILE D 203
ILE D 151
ILE D 159
 None
 0.99A 3s53B-6eojD:
undetectable		 3s53B-6eojD:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_B_SAMB500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 6eoj PROTEIN CFT1
POLYADENYLATION
FACTOR SUBUNIT
2,POLYADENYLATION
FACTOR SUBUNIT 2
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		3 / 3 HIS D  48
SER A1173
ASN A1016
 None
 0.87A 3s8pB-6eojD:
undetectable		 3s8pB-6eojD:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_A_SUEA1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		4 / 4 PHE A  90
TYR A  26
ILE A  66
LEU A  77
 None
 1.50A 3sudA-6eojA:
undetectable		 3sudA-6eojA:
10.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_B_BEZB1_0
(HEME-BINDING PROTEIN
HUTZ)		 6eoj PROTEIN CFT1
MRNA
3'-END-PROCESSING
PROTEIN YTH1
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		4 / 6 GLN A1210
PHE B  18
PRO A1201
LEU B  19
 None
 1.39A 3tgvB-6eojA:
undetectable		 3tgvB-6eojA:
7.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_D_BEZD1_0
(HEME-BINDING PROTEIN
HUTZ)		 6eoj PROTEIN CFT1
MRNA
3'-END-PROCESSING
PROTEIN YTH1
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		4 / 6 GLN A1210
PHE B  18
PRO A1201
LEU B  19
 None
 1.22A 3tgvD-6eojA:
undetectable		 3tgvD-6eojA:
7.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC606_0
(GBAA_1210 PROTEIN)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		4 / 6 GLY A 517
VAL A 540
SER A 538
THR A 515
 None
 1.11A 3tj7C-6eojA:
undetectable
3tj7D-6eojA:
undetectable		 3tj7C-6eojA:
9.60
3tj7D-6eojA:
9.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_D_ACTD605_0
(GBAA_1210 PROTEIN)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		4 / 6 VAL A 540
SER A 538
THR A 515
GLY A 517
 None
 1.13A 3tj7C-6eojA:
undetectable
3tj7D-6eojA:
undetectable		 3tj7C-6eojA:
9.60
3tj7D-6eojA:
9.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_B_SAMB401_1
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		4 / 5 HIS A 550
SER A 549
THR A 943
GLU A 401
 None
 1.43A 3tm4B-6eojA:
undetectable		 3tm4B-6eojA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_B_SALB404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 6eoj POLYADENYLATION
FACTOR SUBUNIT
2,POLYADENYLATION
FACTOR SUBUNIT 2
PROTEIN CFT1
(Saccharomyces
cerevisiae) 		5 / 7 ASN D  69
ALA D  70
PRO D  67
TYR D  43
ALA A1143
 None
 1.39A 3twpB-6eojD:
undetectable		 3twpB-6eojD:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_C_SALC404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 6eoj POLYADENYLATION
FACTOR SUBUNIT
2,POLYADENYLATION
FACTOR SUBUNIT 2
PROTEIN CFT1
(Saccharomyces
cerevisiae) 		5 / 7 ASN D  69
ALA D  70
PRO D  67
TYR D  43
ALA A1143
 None
 1.40A 3twpC-6eojD:
undetectable		 3twpC-6eojD:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_D_SALD404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 6eoj POLYADENYLATION
FACTOR SUBUNIT
2,POLYADENYLATION
FACTOR SUBUNIT 2
PROTEIN CFT1
(Saccharomyces
cerevisiae) 		5 / 5 ASN D  69
ALA D  70
PRO D  67
TYR D  43
ALA A1143
 None
 1.37A 3twpD-6eojD:
undetectable		 3twpD-6eojD:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VNS_A_DVAA602_0
(NRPS ADENYLATION
PROTEIN CYTC1)		 6eoj PROTEIN CFT1
MRNA
3'-END-PROCESSING
PROTEIN YTH1
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		4 / 7 ASP B  30
GLY A1095
PHE A1152
LYS A1032
 None
 1.15A 3vnsA-6eojB:
undetectable		 3vnsA-6eojB:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1507_0
(FERROCHELATASE,
MITOCHONDRIAL)		 6eoj PROTEIN CFT1
POLYADENYLATION
FACTOR SUBUNIT
2,POLYADENYLATION
FACTOR SUBUNIT 2
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		3 / 3 ARG A1192
LYS A 119
ARG D  46
 None
 1.41A 3w1wA-6eojA:
undetectable
3w1wB-6eojA:
undetectable		 3w1wA-6eojA:
14.53
3w1wB-6eojA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_B_CHDB506_0
(FERROCHELATASE,
MITOCHONDRIAL)		 6eoj PROTEIN CFT1
POLYADENYLATION
FACTOR SUBUNIT
2,POLYADENYLATION
FACTOR SUBUNIT 2
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		3 / 3 ARG D  46
ARG A1192
LYS A 119
 None
 1.42A 3w1wA-6eojD:
undetectable
3w1wB-6eojD:
undetectable		 3w1wA-6eojD:
19.71
3w1wB-6eojD:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W2T_A_LF7A801_1
(DIPEPTIDYL PEPTIDASE
4)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		5 / 12 ARG A 827
GLU A  53
TYR A 922
TYR A  40
VAL A  31
 None
 1.31A 3w2tA-6eojA:
4.7		 3w2tA-6eojA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W2T_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		5 / 12 ARG A 827
GLU A  53
TYR A 922
TYR A  40
VAL A  31
 None
 1.33A 3w2tB-6eojA:
5.8		 3w2tB-6eojA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1003_1
(HEMOLYTIC LECTIN
CEL-III)		 6eoj POLYADENYLATION
FACTOR SUBUNIT
2,POLYADENYLATION
FACTOR SUBUNIT 2
PROTEIN CFT1
(Saccharomyces
cerevisiae) 		4 / 4 ASP D  64
GLU A 987
GLY A 988
TYR D  61
 None
 1.34A 3w9tA-6eojD:
0.0		 3w9tA-6eojD:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1004_1
(HEMOLYTIC LECTIN
CEL-III)		 6eoj POLYADENYLATION
FACTOR SUBUNIT
2,POLYADENYLATION
FACTOR SUBUNIT 2
PROTEIN CFT1
(Saccharomyces
cerevisiae) 		4 / 5 ASP D  64
GLU A 987
GLY A 988
TYR D  61
 None
 1.22A 3w9tA-6eojD:
undetectable		 3w9tA-6eojD:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB502_1
(HEMOLYTIC LECTIN
CEL-III)		 6eoj POLYADENYLATION
FACTOR SUBUNIT
2,POLYADENYLATION
FACTOR SUBUNIT 2
PROTEIN CFT1
(Saccharomyces
cerevisiae) 		5 / 6 ASP D  64
GLU A 987
GLY A 988
LEU D  53
TYR D  61
 None
 1.27A 3w9tB-6eojD:
undetectable		 3w9tB-6eojD:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB507_1
(HEMOLYTIC LECTIN
CEL-III)		 6eoj POLYADENYLATION
FACTOR SUBUNIT
2,POLYADENYLATION
FACTOR SUBUNIT 2
PROTEIN CFT1
(Saccharomyces
cerevisiae) 		4 / 4 ASP D  64
GLU A 987
GLY A 988
TYR D  61
 None
 1.34A 3w9tB-6eojD:
0.0		 3w9tB-6eojD:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1002_1
(HEMOLYTIC LECTIN
CEL-III)		 6eoj POLYADENYLATION
FACTOR SUBUNIT
2,POLYADENYLATION
FACTOR SUBUNIT 2
PROTEIN CFT1
(Saccharomyces
cerevisiae) 		4 / 5 ASP D  64
GLU A 987
GLY A 988
TYR D  61
 None
 1.24A 3w9tC-6eojD:
undetectable		 3w9tC-6eojD:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD507_1
(HEMOLYTIC LECTIN
CEL-III)		 6eoj POLYADENYLATION
FACTOR SUBUNIT
2,POLYADENYLATION
FACTOR SUBUNIT 2
PROTEIN CFT1
(Saccharomyces
cerevisiae) 		4 / 5 ASP D  64
GLU A 987
GLY A 988
TYR D  61
 None
 1.34A 3w9tD-6eojD:
undetectable		 3w9tD-6eojD:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD512_1
(HEMOLYTIC LECTIN
CEL-III)		 6eoj POLYADENYLATION
FACTOR SUBUNIT
2,POLYADENYLATION
FACTOR SUBUNIT 2
PROTEIN CFT1
(Saccharomyces
cerevisiae) 		4 / 5 ASP D  64
GLU A 987
GLY A 988
TYR D  61
 None
 1.24A 3w9tD-6eojD:
undetectable		 3w9tD-6eojD:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE502_1
(HEMOLYTIC LECTIN
CEL-III)		 6eoj POLYADENYLATION
FACTOR SUBUNIT
2,POLYADENYLATION
FACTOR SUBUNIT 2
PROTEIN CFT1
(Saccharomyces
cerevisiae) 		5 / 6 ASP D  64
GLU A 987
GLY A 988
LEU D  53
TYR D  61
 None
 1.28A 3w9tE-6eojD:
undetectable		 3w9tE-6eojD:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE503_1
(HEMOLYTIC LECTIN
CEL-III)		 6eoj POLYADENYLATION
FACTOR SUBUNIT
2,POLYADENYLATION
FACTOR SUBUNIT 2
PROTEIN CFT1
(Saccharomyces
cerevisiae) 		4 / 4 ASP D  64
GLU A 987
GLY A 988
TYR D  61
 None
 1.34A 3w9tE-6eojD:
0.0		 3w9tE-6eojD:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF502_1
(HEMOLYTIC LECTIN
CEL-III)		 6eoj POLYADENYLATION
FACTOR SUBUNIT
2,POLYADENYLATION
FACTOR SUBUNIT 2
PROTEIN CFT1
(Saccharomyces
cerevisiae) 		4 / 4 ASP D  64
GLU A 987
GLY A 988
TYR D  61
 None
 1.35A 3w9tF-6eojD:
0.0		 3w9tF-6eojD:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF503_1
(HEMOLYTIC LECTIN
CEL-III)		 6eoj POLYADENYLATION
FACTOR SUBUNIT
2,POLYADENYLATION
FACTOR SUBUNIT 2
PROTEIN CFT1
(Saccharomyces
cerevisiae) 		5 / 6 ASP D  64
GLU A 987
GLY A 988
LEU D  53
TYR D  61
 None
 1.28A 3w9tF-6eojD:
undetectable		 3w9tF-6eojD:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG502_1
(HEMOLYTIC LECTIN
CEL-III)		 6eoj POLYADENYLATION
FACTOR SUBUNIT
2,POLYADENYLATION
FACTOR SUBUNIT 2
PROTEIN CFT1
(Saccharomyces
cerevisiae) 		4 / 5 ASP D  64
GLU A 987
GLY A 988
TYR D  61
 None
 1.22A 3w9tG-6eojD:
undetectable		 3w9tG-6eojD:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1478_0
(MJ0495-LIKE PROTEIN)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		4 / 7 SER A 543
GLY A1253
SER A 549
THR A 943
 None
 1.03A 4ac9C-6eojA:
undetectable		 4ac9C-6eojA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZW_A_SAMA1451_0
(WBDD)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		5 / 12 GLY A1039
ALA A1041
PHE A1054
ILE A1037
VAL A1090
 None
 1.20A 4azwA-6eojA:
undetectable		 4azwA-6eojA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGJ_A_1PQA304_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		4 / 8 GLN A 754
ILE A 742
GLY A 773
GLU A 775
 None
 1.02A 4fgjA-6eojA:
undetectable
4fgjB-6eojA:
undetectable		 4fgjA-6eojA:
11.49
4fgjB-6eojA:
11.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FZV_A_SAMA401_1
(PUTATIVE
METHYLTRANSFERASE
NSUN4)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		3 / 3 ASP A 856
ARG A 900
ASP A 793
 None
 0.83A 4fzvA-6eojA:
undetectable		 4fzvA-6eojA:
13.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I13_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		3 / 3 ASP A1252
ARG A 506
THR A  34
 None
 0.86A 4i13A-6eojA:
undetectable		 4i13A-6eojA:
8.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K17_B_OHBB701_0
(LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A)		 6eoj PROTEIN CFT1
POLYADENYLATION
FACTOR SUBUNIT
2,POLYADENYLATION
FACTOR SUBUNIT 2
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		4 / 5 GLU A1046
ARG D 379
PRO D  38
SER D  36
 None
 1.38A 4k17B-6eojA:
4.1		 4k17B-6eojA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K17_B_OHBB701_0
(LEUCINE-RICH
REPEAT-CONTAINING
PROTEIN 16A)		 6eoj PROTEIN CFT1
POLYADENYLATION
FACTOR SUBUNIT
2,POLYADENYLATION
FACTOR SUBUNIT 2
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		4 / 5 GLU A1046
ARG D 379
PRO D  38
SER D  37
 None
 1.46A 4k17B-6eojA:
4.1		 4k17B-6eojA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KEB_B_FOLB202_0
(DIHYDROFOLATE
REDUCTASE)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		6 / 12 ILE A 292
ALA A 300
LEU A 277
GLN A 217
ILE A 252
LEU A 219
 None
 1.35A 4kebB-6eojA:
undetectable		 4kebB-6eojA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KMM_A_CHDA503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 6eoj PROTEIN CFT1
POLYADENYLATION
FACTOR SUBUNIT
2,POLYADENYLATION
FACTOR SUBUNIT 2
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		4 / 7 ARG A1108
PRO A1050
SER D  32
VAL A1083
 None
 0.84A 4kmmA-6eojA:
undetectable		 4kmmA-6eojA:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOU_A_C04A206_1
(UNCHARACTERIZED
PROTEIN)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		5 / 10 TYR A1184
GLY A1180
ASN A1179
PHE A1176
LEU A1137
 None
 1.44A 4kouA-6eojA:
undetectable		 4kouA-6eojA:
8.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_A_SAMA301_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		3 / 3 SER A 416
ASP A 421
ASP A  45
 None
 0.91A 4mwzA-6eojA:
undetectable		 4mwzA-6eojA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_A_SAMA301_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		3 / 3 SER A 861
ASP A 877
ASP A  45
 None
 0.78A 4mwzA-6eojA:
undetectable		 4mwzA-6eojA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_C_ADNC401_2
(ADENOSINE KINASE)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		4 / 5 ASN A 576
LEU A 586
SER A 601
LEU A 566
 None
 1.10A 4n09C-6eojA:
undetectable		 4n09C-6eojA:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N16_A_CHDA301_0
(CARBONIC ANHYDRASE 2)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		4 / 8 ILE A 213
HIS A 282
PHE A 135
THR A 342
 None
 0.84A 4n16A-6eojA:
undetectable		 4n16A-6eojA:
10.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P3R_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		3 / 3 ASP A1252
ARG A 506
THR A  34
 None
 0.87A 4p3rA-6eojA:
undetectable		 4p3rA-6eojA:
8.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_2
(GLUCOCORTICOID
RECEPTOR)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		3 / 3 MET A1018
MET A1022
TYR A1057
 None
 1.40A 4p6xI-6eojA:
undetectable		 4p6xI-6eojA:
10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4POO_B_SAMB301_0
(PUTATIVE RNA
METHYLASE)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		5 / 12 GLY A1146
ASP A1189
ASP A1142
ILE A1124
SER A1088
 None
 1.33A 4pooB-6eojA:
undetectable		 4pooB-6eojA:
10.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5)		 6eoj POLYADENYLATION
FACTOR SUBUNIT
2,POLYADENYLATION
FACTOR SUBUNIT 2
(Saccharomyces
cerevisiae) 		4 / 7 THR D 354
ALA D 368
THR D 367
ALA D 366
 None
 0.94A 4qw0K-6eojD:
undetectable		 4qw0K-6eojD:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5)		 6eoj POLYADENYLATION
FACTOR SUBUNIT
2,POLYADENYLATION
FACTOR SUBUNIT 2
(Saccharomyces
cerevisiae) 		4 / 7 THR D 354
ALA D 368
THR D 367
ALA D 366
 None
 0.95A 4qw0Y-6eojD:
undetectable		 4qw0Y-6eojD:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		4 / 7 ARG A1096
ILE A1117
GLN A1111
ILE A1023
 None
 1.05A 4w5oA-6eojA:
undetectable		 4w5oA-6eojA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_D_LOCD502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		4 / 4 ASN A1246
SER A1173
ALA A1186
VAL A1196
 None
 1.34A 4x1kC-6eojA:
undetectable		 4x1kC-6eojA:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJ7_A_ADNA303_1
(5'/3'-NUCLEOTIDASE
SURE)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		5 / 10 GLY A  64
ASP A 126
ILE A  85
LEU A  77
LEU A 123
 None
 1.20A 4xj7A-6eojA:
undetectable
4xj7B-6eojA:
undetectable		 4xj7A-6eojA:
10.99
4xj7B-6eojA:
10.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		4 / 6 ARG A1096
ILE A1117
GLN A1111
ILE A1023
 None
 1.07A 4z4dA-6eojA:
undetectable		 4z4dA-6eojA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDY_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		5 / 12 GLY A 548
ILE A 522
GLY A 517
THR A 515
LEU A 947
 None
 1.23A 4zdyA-6eojA:
undetectable		 4zdyA-6eojA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_O_EVPO2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		4 / 6 SER A 557
GLU A 536
GLY A 806
GLY A 843
 None
 0.93A 5cdnC-6eojA:
undetectable
5cdnD-6eojA:
undetectable		 5cdnC-6eojA:
16.32
5cdnD-6eojA:
9.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_P_EVPP2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		4 / 6 SER A 557
GLU A 536
GLY A 806
GLY A 843
 None
 0.95A 5cdnT-6eojA:
undetectable
5cdnU-6eojA:
undetectable		 5cdnT-6eojA:
16.32
5cdnU-6eojA:
9.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CPR_B_SAMB402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 6eoj PROTEIN CFT1
POLYADENYLATION
FACTOR SUBUNIT
2,POLYADENYLATION
FACTOR SUBUNIT 2
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		3 / 3 HIS D  48
SER A1173
ASN A1016
 None
 0.92A 5cprB-6eojD:
undetectable		 5cprB-6eojD:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DNU_A_BEZA319_0
(SHKAI2IB)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		4 / 5 GLN A 740
ILE A 742
ILE A 704
TYR A 770
 None
 1.25A 5dnuA-6eojA:
undetectable		 5dnuA-6eojA:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DNV_A_BEZA304_0
(SHKAI2IB)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		4 / 5 GLN A 740
ILE A 742
ILE A 704
TYR A 770
 None
 1.19A 5dnvA-6eojA:
undetectable		 5dnvA-6eojA:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_1
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		6 / 12 LEU A 772
PRO A 696
ASP A 676
LEU A 669
PHE A 734
ILE A 677
 None
 1.48A 5dv4A-6eojA:
undetectable		 5dv4A-6eojA:
14.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB201_0
(HYDROXYNITRILE LYASE)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		5 / 11 VAL A1259
VAL A   3
PHE A1310
ILE A 832
ILE A1343
 None
 1.11A 5e4dB-6eojA:
undetectable		 5e4dB-6eojA:
10.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_A_VDYA201_2
(CDL2.2)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 333
ILE A 375
LEU A 299
GLY A 295
TYR A 374
 None
 1.19A 5ienA-6eojA:
1.8		 5ienA-6eojA:
7.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEO_A_VDYA206_2
(CDL2.3A)		 6eoj POLYADENYLATION
FACTOR SUBUNIT
2,POLYADENYLATION
FACTOR SUBUNIT 2
(Saccharomyces
cerevisiae) 		4 / 8 ILE D 364
LEU D 329
ILE D 345
LEU D 108
 None
 0.93A 5ieoA-6eojD:
2.5		 5ieoA-6eojD:
15.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB5_A_ADNA401_2
(ADENOSINE KINASE)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		4 / 4 ASN A 576
LEU A 586
SER A 601
LEU A 566
 None
 1.14A 5kb5A-6eojA:
undetectable		 5kb5A-6eojA:
14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4T_A_BEZA507_0
(BETA-LACTAMASE VIM-2)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		3 / 3 THR A 826
HIS A  57
ASN A1311
 None
 0.77A 5n4tA-6eojA:
undetectable		 5n4tA-6eojA:
10.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND4_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 6eoj POLYADENYLATION
FACTOR SUBUNIT
2,POLYADENYLATION
FACTOR SUBUNIT 2
PROTEIN CFT1
(Saccharomyces
cerevisiae) 		5 / 12 ASP A  62
LEU A 117
ALA A  83
PHE A 109
ARG D  74
 None
 1.10A 5nd4B-6eojA:
undetectable		 5nd4B-6eojA:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND7_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 6eoj POLYADENYLATION
FACTOR SUBUNIT
2,POLYADENYLATION
FACTOR SUBUNIT 2
PROTEIN CFT1
(Saccharomyces
cerevisiae) 		5 / 12 ASP A  62
LEU A 117
ALA A  83
PHE A 109
ARG D  74
 None
 1.03A 5nd7B-6eojA:
undetectable		 5nd7B-6eojA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NM5_B_LOCB502_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		4 / 4 ASN A1246
SER A1173
ALA A1186
VAL A1196
 None
 1.39A 5nm5A-6eojA:
undetectable		 5nm5A-6eojA:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Q1S_A_AWYA1103_0
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		4 / 6 VAL A   3
LYS A   1
ILE A1346
LYS A1265
 None
 1.42A 5q1sA-6eojA:
undetectable		 5q1sA-6eojA:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		4 / 8 THR A 635
THR A 589
GLN A 573
TRP A 575
 None
 1.42A 5tzoA-6eojA:
undetectable		 5tzoA-6eojA:
9.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UVM_B_ADNB207_1
(HISTIDINE TRIAD
(HIT) PROTEIN)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		5 / 12 VAL A 670
ILE A 668
ILE A 632
ILE A 652
VAL A 658
 None
 0.82A 5uvmB-6eojA:
undetectable		 5uvmB-6eojA:
7.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_F_CVIF301_1
(REGULATORY PROTEIN
TETR)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		4 / 8 ILE A1023
TYR A1157
VAL A1116
ASP A1058
 None
 1.02A 5vlmF-6eojA:
undetectable		 5vlmF-6eojA:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA503_1
(CYTOCHROME P450 2C9)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		6 / 12 ILE A 284
LEU A 314
LEU A 246
PRO A 247
THR A 248
LEU A 230
 None
 1.43A 5xxiA-6eojA:
undetectable		 5xxiA-6eojA:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YVN_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)		 6eoj PROTEIN CFT1
POLYADENYLATION
FACTOR SUBUNIT
2,POLYADENYLATION
FACTOR SUBUNIT 2
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		4 / 6 GLU A 987
LYS A 369
LEU A 368
LEU D  53
 None
 1.20A 5yvnA-6eojA:
undetectable		 5yvnA-6eojA:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZSF_A_6T0A910_0
(TOLL-LIKE RECEPTOR 7)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		4 / 7 LEU A 253
ILE A 271
THR A 270
TYR A 250
 None
 1.00A 5zsfA-6eojA:
undetectable
5zsfB-6eojA:
undetectable		 5zsfA-6eojA:
4.83
5zsfB-6eojA:
4.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_A_SAMA401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		3 / 3 ASP A 856
ARG A 900
ASP A 793
 None
 0.65A 5zvgA-6eojA:
undetectable		 5zvgA-6eojA:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_B_SAMB401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		3 / 3 ASP A 856
ARG A 900
ASP A 793
 None
 0.70A 5zvgB-6eojA:
undetectable		 5zvgB-6eojA:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AK3_A_P2EA1201_1
(PROSTAGLANDIN E2
RECEPTOR EP3
SUBTYPE,SOLUBLE
CYTOCHROME B562)		 6eoj PROTEIN CFT1
MRNA
3'-END-PROCESSING
PROTEIN YTH1
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		4 / 4 PRO B   1
MET A1228
GLY A1248
VAL A 516
 None
 1.48A 6ak3A-6eojB:
undetectable		 6ak3A-6eojB:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AZ3_1_PAR11802_1
(RRNA ALPHA
RIBOSOMAL PROTEIN
UL4
RIBOSOMAL PROTEIN
UL15
RIBOSOMAL PROTEIN
EL15)		 6eoj MRNA
3'-END-PROCESSING
PROTEIN YTH1
PROTEIN CFT1
(Saccharomyces
cerevisiae) 		3 / 3 ARG B  31
LYS A1030
ARG B  20
 None
 1.18A 6az3C-6eojB:
undetectable
6az3L-6eojB:
undetectable
6az3M-6eojB:
undetectable		 6az3C-6eojB:
16.35
6az3L-6eojB:
17.00
6az3M-6eojB:
15.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B1E_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		5 / 12 ARG A 827
GLU A  53
TYR A 922
TYR A  40
VAL A  31
 None
 1.33A 6b1eB-6eojA:
6.0		 6b1eB-6eojA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_A_9F2A302_1
(BETA-LACTAMASE)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		5 / 9 ILE A 631
TYR A 640
THR A 635
THR A 619
ASP A 583
 None
 1.48A 6b68A-6eojA:
undetectable
6b68B-6eojA:
undetectable		 6b68A-6eojA:
5.09
6b68B-6eojA:
5.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_C_9F2C302_1
(BETA-LACTAMASE)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		5 / 10 ILE A 631
TYR A 640
THR A 635
THR A 619
ASP A 583
 None
 1.48A 6b68C-6eojA:
undetectable
6b68D-6eojA:
undetectable		 6b68C-6eojA:
5.09
6b68D-6eojA:
5.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_C_9F2C302_1
(BETA-LACTAMASE)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		5 / 9 ILE A 631
TYR A 640
THR A 635
THR A 619
ASP A 583
 None
 1.49A 6b69C-6eojA:
undetectable
6b69D-6eojA:
undetectable		 6b69C-6eojA:
5.09
6b69D-6eojA:
5.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_A_9F2A302_1
(BETA-LACTAMASE)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		5 / 9 ILE A 631
TYR A 640
THR A 635
THR A 619
ASP A 583
 None
 1.49A 6b6aA-6eojA:
undetectable
6b6aB-6eojA:
undetectable		 6b6aA-6eojA:
5.09
6b6aB-6eojA:
5.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_C_9F2C302_1
(BETA-LACTAMASE)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		5 / 9 ILE A 631
TYR A 640
THR A 635
THR A 619
ASP A 583
 None
 1.47A 6b6aC-6eojA:
undetectable
6b6aD-6eojA:
undetectable		 6b6aC-6eojA:
5.09
6b6aD-6eojA:
5.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_G_ZOLG401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 6eoj PROTEIN CFT1
POLYADENYLATION
FACTOR SUBUNIT
2,POLYADENYLATION
FACTOR SUBUNIT 2
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		4 / 7 ASP D 148
ASP D 146
GLN A1210
GLN A1148
 None
 1.13A 6g31G-6eojD:
undetectable		 6g31G-6eojD:
9.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_A_TKTA508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		4 / 8 ASP A 590
ILE A 571
ARG A 595
ASN A 910
 None
 1.09A 6hisA-6eojA:
undetectable
6hisB-6eojA:
undetectable		 6hisA-6eojA:
4.71
6hisB-6eojA:
4.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_B_TKTB508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		4 / 8 ASP A 590
ILE A 571
ARG A 595
ASN A 910
 None
 1.08A 6hisB-6eojA:
undetectable
6hisC-6eojA:
undetectable		 6hisB-6eojA:
4.71
6hisC-6eojA:
4.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_C_TKTC508_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		4 / 8 ASP A 590
ILE A 571
ARG A 595
ASN A 910
 None
 1.08A 6hisC-6eojA:
undetectable
6hisD-6eojA:
undetectable		 6hisC-6eojA:
4.71
6hisD-6eojA:
4.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_D_TKTD501_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		4 / 8 ASP A 590
ILE A 571
ARG A 595
ASN A 910
 None
 1.08A 6hisD-6eojA:
undetectable
6hisE-6eojA:
undetectable		 6hisD-6eojA:
4.71
6hisE-6eojA:
4.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HIS_E_TKTE501_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 3A)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		4 / 8 ASN A 910
ASP A 590
ILE A 571
ARG A 595
 None
 1.08A 6hisA-6eojA:
undetectable
6hisE-6eojA:
undetectable		 6hisA-6eojA:
4.71
6hisE-6eojA:
4.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_I_PCFI101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 6eoj PROTEIN CFT1
(Saccharomyces
cerevisiae) 		5 / 11 SER A1027
TYR A1157
VAL A1107
ALA A1053
VAL A1116
 None
 1.45A 6hu9A-6eojA:
undetectable
6hu9E-6eojA:
undetectable
6hu9I-6eojA:
undetectable		 6hu9A-6eojA:
14.64
6hu9E-6eojA:
7.96
6hu9I-6eojA:
4.82