SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6eom'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EI6_D_PPFD412_1
(PHOSPHONOACETATE
HYDROLASE)		 6eom MUTT/NUDIX FAMILY
PROTEIN
(Caldithrix
abyssi) 		5 / 8 THR A 451
ASP A 416
HIS A 379
HIS A 375
HIS A 460
 None
None
ZN  A 601 (-3.2A)
None
None
 1.38A 1ei6D-6eomA:
undetectable		 1ei6D-6eomA:
10.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J36_A_LPRA801_1
(ANGIOTENSIN
CONVERTING ENZYME)		 6eom MUTT/NUDIX FAMILY
PROTEIN
(Caldithrix
abyssi) 		5 / 12 THR A 376
HIS A 379
GLU A 380
HIS A 383
GLU A 412
 None
ZN  A 601 (-3.2A)
None
ZN  A 601 (-3.2A)
ZN  A 601 (-1.6A)
 0.48A 1j36A-6eomA:
2.2		 1j36A-6eomA:
8.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J36_B_LPRB802_1
(ANGIOTENSIN
CONVERTING ENZYME)		 6eom MUTT/NUDIX FAMILY
PROTEIN
(Caldithrix
abyssi) 		5 / 12 THR A 376
HIS A 379
GLU A 380
HIS A 383
GLU A 412
 None
ZN  A 601 (-3.2A)
None
ZN  A 601 (-3.2A)
ZN  A 601 (-1.6A)
 0.48A 1j36B-6eomA:
2.3		 1j36B-6eomA:
8.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_A_SAMA801_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 6eom MUTT/NUDIX FAMILY
PROTEIN
(Caldithrix
abyssi) 		4 / 6 ASP A 221
TYR A 217
ASN A 215
GLU A 326
 None
 1.05A 1rjdA-6eomA:
undetectable		 1rjdA-6eomA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_B_SAMB802_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 6eom MUTT/NUDIX FAMILY
PROTEIN
(Caldithrix
abyssi) 		4 / 6 ASP A 221
TYR A 217
ASN A 215
GLU A 326
 None
 1.03A 1rjdB-6eomA:
undetectable		 1rjdB-6eomA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 6eom MUTT/NUDIX FAMILY
PROTEIN
(Caldithrix
abyssi) 		4 / 6 ASP A 221
TYR A 217
ASN A 215
GLU A 326
 None
 1.01A 1rjdC-6eomA:
undetectable		 1rjdC-6eomA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_C_ADNC1503_1
(CLASS B ACID
PHOSPHATASE)		 6eom MUTT/NUDIX FAMILY
PROTEIN
(Caldithrix
abyssi) 		4 / 8 ASP A 416
PHE A 444
TYR A 477
GLY A 463
 None
 0.99A 1rmtC-6eomA:
undetectable		 1rmtC-6eomA:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_A_CRNA401_1
(CREATININE
AMIDOHYDROLASE)		 6eom MUTT/NUDIX FAMILY
PROTEIN
(Caldithrix
abyssi) 		4 / 8 GLU A 412
HIS A 379
HIS A 383
GLU A 380
 ZN  A 601 (-1.6A)
ZN  A 601 (-3.2A)
ZN  A 601 (-3.2A)
None
 0.91A 1v7zA-6eomA:
undetectable		 1v7zA-6eomA:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_B_CRNB3401_1
(CREATININE
AMIDOHYDROLASE)		 6eom MUTT/NUDIX FAMILY
PROTEIN
(Caldithrix
abyssi) 		4 / 8 GLU A 412
HIS A 379
HIS A 383
GLU A 380
 ZN  A 601 (-1.6A)
ZN  A 601 (-3.2A)
ZN  A 601 (-3.2A)
None
 0.92A 1v7zB-6eomA:
undetectable		 1v7zB-6eomA:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_C_CRNC4401_1
(CREATININE
AMIDOHYDROLASE)		 6eom MUTT/NUDIX FAMILY
PROTEIN
(Caldithrix
abyssi) 		4 / 8 GLU A 412
HIS A 379
HIS A 383
GLU A 380
 ZN  A 601 (-1.6A)
ZN  A 601 (-3.2A)
ZN  A 601 (-3.2A)
None
 0.93A 1v7zC-6eomA:
undetectable		 1v7zC-6eomA:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_D_CRND5401_1
(CREATININE
AMIDOHYDROLASE)		 6eom MUTT/NUDIX FAMILY
PROTEIN
(Caldithrix
abyssi) 		4 / 8 GLU A 412
HIS A 379
HIS A 383
GLU A 380
 ZN  A 601 (-1.6A)
ZN  A 601 (-3.2A)
ZN  A 601 (-3.2A)
None
 0.94A 1v7zD-6eomA:
undetectable		 1v7zD-6eomA:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_E_CRNE6401_1
(CREATININE
AMIDOHYDROLASE)		 6eom MUTT/NUDIX FAMILY
PROTEIN
(Caldithrix
abyssi) 		4 / 8 GLU A 412
HIS A 379
HIS A 383
GLU A 380
 ZN  A 601 (-1.6A)
ZN  A 601 (-3.2A)
ZN  A 601 (-3.2A)
None
 0.94A 1v7zE-6eomA:
undetectable		 1v7zE-6eomA:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_F_CRNF7401_1
(CREATININE
AMIDOHYDROLASE)		 6eom MUTT/NUDIX FAMILY
PROTEIN
(Caldithrix
abyssi) 		4 / 8 GLU A 412
HIS A 379
HIS A 383
GLU A 380
 ZN  A 601 (-1.6A)
ZN  A 601 (-3.2A)
ZN  A 601 (-3.2A)
None
 0.93A 1v7zF-6eomA:
undetectable		 1v7zF-6eomA:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_A_LPRA705_1
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 6eom MUTT/NUDIX FAMILY
PROTEIN
(Caldithrix
abyssi) 		5 / 12 ALA A 319
HIS A 379
GLU A 380
HIS A 383
GLU A 412
 None
ZN  A 601 (-3.2A)
None
ZN  A 601 (-3.2A)
ZN  A 601 (-1.6A)
 0.78A 2c6nA-6eomA:
2.0		 2c6nA-6eomA:
8.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC8_0
(ACTINOMYCIN D)		 6eom MUTT/NUDIX FAMILY
PROTEIN
(Caldithrix
abyssi) 		3 / 3 PRO A 546
THR A  42
PRO A  41
 None
 0.83A 2d55C-6eomA:
undetectable		 2d55C-6eomA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_A_097A1001_1
(ADAMTS-1)		 6eom MUTT/NUDIX FAMILY
PROTEIN
(Caldithrix
abyssi) 		5 / 9 LEU A 318
THR A 376
HIS A 379
GLU A 380
HIS A 383
 LYS  A 606 ( 4.1A)
None
ZN  A 601 (-3.2A)
None
ZN  A 601 (-3.2A)
 0.64A 2jihA-6eomA:
undetectable		 2jihA-6eomA:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_1
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 6eom MUTT/NUDIX FAMILY
PROTEIN
(Caldithrix
abyssi) 		5 / 12 THR A 231
ALA A 196
ALA A 192
ILE A 257
LEU A 554
 CL  A 602 (-4.6A)
None
None
None
None
 1.11A 2nyrA-6eomA:
undetectable		 2nyrA-6eomA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YOE_C_FL7C1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 6eom MUTT/NUDIX FAMILY
PROTEIN
(Caldithrix
abyssi) 		4 / 8 GLY A 371
ILE A 493
VAL A 486
TYR A 477
 None
 0.90A 2yoeB-6eomA:
3.4
2yoeC-6eomA:
3.5		 2yoeB-6eomA:
14.66
2yoeC-6eomA:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_C_2FAC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 6eom MUTT/NUDIX FAMILY
PROTEIN
(Caldithrix
abyssi) 		4 / 5 LEU A 318
GLN A 316
THR A 451
HIS A 460
 LYS  A 606 ( 4.1A)
NA  A 607 ( 4.9A)
None
None
 1.09A 2zj0C-6eomA:
undetectable		 2zj0C-6eomA:
11.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_A_CRNA303_1
(CREATININE
AMIDOHYDROLASE)		 6eom MUTT/NUDIX FAMILY
PROTEIN
(Caldithrix
abyssi) 		4 / 8 GLU A 412
HIS A 379
HIS A 383
GLU A 380
 ZN  A 601 (-1.6A)
ZN  A 601 (-3.2A)
ZN  A 601 (-3.2A)
None
 0.93A 3a6jA-6eomA:
undetectable		 3a6jA-6eomA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_B_CRNB304_1
(CREATININE
AMIDOHYDROLASE)		 6eom MUTT/NUDIX FAMILY
PROTEIN
(Caldithrix
abyssi) 		4 / 7 GLU A 412
HIS A 379
HIS A 383
GLU A 380
 ZN  A 601 (-1.6A)
ZN  A 601 (-3.2A)
ZN  A 601 (-3.2A)
None
 0.90A 3a6jB-6eomA:
undetectable		 3a6jB-6eomA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_C_CRNC305_1
(CREATININE
AMIDOHYDROLASE)		 6eom MUTT/NUDIX FAMILY
PROTEIN
(Caldithrix
abyssi) 		4 / 8 GLU A 412
HIS A 379
HIS A 383
GLU A 380
 ZN  A 601 (-1.6A)
ZN  A 601 (-3.2A)
ZN  A 601 (-3.2A)
None
 0.91A 3a6jC-6eomA:
undetectable		 3a6jC-6eomA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_E_CRNE306_1
(CREATININE
AMIDOHYDROLASE)		 6eom MUTT/NUDIX FAMILY
PROTEIN
(Caldithrix
abyssi) 		4 / 8 GLU A 412
HIS A 379
HIS A 383
GLU A 380
 ZN  A 601 (-1.6A)
ZN  A 601 (-3.2A)
ZN  A 601 (-3.2A)
None
 0.94A 3a6jE-6eomA:
undetectable		 3a6jE-6eomA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_F_CRNF307_1
(CREATININE
AMIDOHYDROLASE)		 6eom MUTT/NUDIX FAMILY
PROTEIN
(Caldithrix
abyssi) 		4 / 8 GLU A 412
HIS A 379
HIS A 383
GLU A 380
 ZN  A 601 (-1.6A)
ZN  A 601 (-3.2A)
ZN  A 601 (-3.2A)
None
 0.90A 3a6jF-6eomA:
undetectable		 3a6jF-6eomA:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_B_ADNB500_2
(ADENOSYLHOMOCYSTEINA
SE)		 6eom MUTT/NUDIX FAMILY
PROTEIN
(Caldithrix
abyssi) 		4 / 5 LEU A 318
GLN A 316
THR A 451
HIS A 460
 LYS  A 606 ( 4.1A)
NA  A 607 ( 4.9A)
None
None
 1.09A 3ce6B-6eomA:
undetectable		 3ce6B-6eomA:
11.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HY7_A_097A801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 6eom MUTT/NUDIX FAMILY
PROTEIN
(Caldithrix
abyssi) 		5 / 9 LEU A 318
THR A 376
HIS A 379
GLU A 380
HIS A 383
 LYS  A 606 ( 4.1A)
None
ZN  A 601 (-3.2A)
None
ZN  A 601 (-3.2A)
 0.52A 3hy7A-6eomA:
undetectable		 3hy7A-6eomA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HY7_B_097B801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 6eom MUTT/NUDIX FAMILY
PROTEIN
(Caldithrix
abyssi) 		5 / 9 LEU A 318
THR A 376
HIS A 379
GLU A 380
HIS A 383
 LYS  A 606 ( 4.1A)
None
ZN  A 601 (-3.2A)
None
ZN  A 601 (-3.2A)
 0.59A 3hy7B-6eomA:
undetectable		 3hy7B-6eomA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QOW_A_SAMA417_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE)		 6eom MUTT/NUDIX FAMILY
PROTEIN
(Caldithrix
abyssi) 		3 / 3 THR A 451
ASP A 416
GLU A 380
 None
 0.85A 3qowA-6eomA:
undetectable		 3qowA-6eomA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_2
(CARBONIC ANHYDRASE)		 6eom MUTT/NUDIX FAMILY
PROTEIN
(Caldithrix
abyssi) 		3 / 3 GLN A  76
PHE A 253
TYR A 178
 None
None
EDO  A 603 (-4.5A)
 0.85A 3ucjB-6eomA:
undetectable		 3ucjB-6eomA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_B_AZMB229_1
(CARBONIC ANHYDRASE)		 6eom MUTT/NUDIX FAMILY
PROTEIN
(Caldithrix
abyssi) 		3 / 3 GLN A  76
PHE A 253
TYR A 178
 None
None
EDO  A 603 (-4.5A)
 0.87A 3ucjA-6eomA:
undetectable		 3ucjA-6eomA:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VRI_A_1KXA301_1
(HLA CLASS I
HISTOCOMPATIBILITY
ANTIGEN, B-57 ALPHA
CHAIN
10-MER PEPTIDE)		 6eom MUTT/NUDIX FAMILY
PROTEIN
(Caldithrix
abyssi) 		5 / 10 TYR A 523
VAL A 466
TYR A 470
ILE A 448
ILE A 530
 None
 1.43A 3vriA-6eomA:
undetectable
3vriC-6eomA:
undetectable		 3vriA-6eomA:
16.83
3vriC-6eomA:
10.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 6eom MUTT/NUDIX FAMILY
PROTEIN
(Caldithrix
abyssi) 		4 / 7 TYR A  46
ASN A  61
TYR A  63
GLU A  60
 None
 1.14A 4mi4A-6eomA:
undetectable
4mi4C-6eomA:
undetectable		 4mi4A-6eomA:
21.47
4mi4C-6eomA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P3Q_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 6eom MUTT/NUDIX FAMILY
PROTEIN
(Caldithrix
abyssi) 		4 / 5 ASP A 111
LEU A 113
ARG A 453
ARG A  34
 None
 1.44A 4p3qA-6eomA:
undetectable		 4p3qA-6eomA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_1
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		 6eom MUTT/NUDIX FAMILY
PROTEIN
(Caldithrix
abyssi) 		5 / 12 LEU A 351
HIS A 460
ASN A 464
LEU A 471
HIS A 375
 None
 1.35A 5dv4A-6eomA:
undetectable		 5dv4A-6eomA:
10.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMF_A_6U9A1301_1
(ION TRANSPORT
PROTEIN)		 6eom MUTT/NUDIX FAMILY
PROTEIN
(Caldithrix
abyssi) 		4 / 6 GLY A 371
GLU A 370
TYR A 432
ILE A 427
 None
 0.89A 5kmfA-6eomA:
undetectable
5kmfC-6eomA:
3.1		 5kmfA-6eomA:
16.67
5kmfC-6eomA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGK_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6eom MUTT/NUDIX FAMILY
PROTEIN
(Caldithrix
abyssi) 		3 / 3 VAL A 486
TYR A 477
GLN A 478
 None
 0.75A 5qgkA-6eomA:
undetectable		 5qgkA-6eomA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGR_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6eom MUTT/NUDIX FAMILY
PROTEIN
(Caldithrix
abyssi) 		3 / 3 VAL A 486
TYR A 477
GLN A 478
 None
 0.76A 5qgrA-6eomA:
undetectable		 5qgrA-6eomA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGT_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 6eom MUTT/NUDIX FAMILY
PROTEIN
(Caldithrix
abyssi) 		3 / 3 VAL A 486
TYR A 477
GLN A 478
 None
 0.76A 5qgtA-6eomA:
undetectable		 5qgtA-6eomA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YJ1_T_6ELT501_0
(PROTEIN CEREBLON)		 6eom MUTT/NUDIX FAMILY
PROTEIN
(Caldithrix
abyssi) 		4 / 8 HIS A 460
THR A 451
HIS A 343
PHE A 436
 None
 1.28A 5yj1k-6eomA:
undetectable
5yj1t-6eomA:
undetectable		 5yj1k-6eomA:
undetectable
5yj1t-6eomA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRZ_A_H8JA1206_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 6eom MUTT/NUDIX FAMILY
PROTEIN
(Caldithrix
abyssi) 		5 / 12 LEU A 377
PHE A 271
GLY A 430
PHE A 436
ASN A 423
 None
 1.07A 6drzA-6eomA:
2.5		 6drzA-6eomA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA807_0
(GEPHYRIN)		 6eom MUTT/NUDIX FAMILY
PROTEIN
(Caldithrix
abyssi) 		4 / 4 PRO A 283
LEU A 418
VAL A 497
ARG A 498
 None
 1.38A 6fgdA-6eomA:
undetectable		 6fgdA-6eomA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_T_PCFT101_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 1,
MITOCHONDRIAL
CYTOCHROME B-C1
COMPLEX SUBUNIT 9
CYTOCHROME B-C1
COMPLEX SUBUNIT
RIESKE,
MITOCHONDRIAL)		 6eom MUTT/NUDIX FAMILY
PROTEIN
(Caldithrix
abyssi) 		4 / 8 ASP A 221
SER A 220
TYR A 239
GLY A 309
 None
 0.83A 6giqL-6eomA:
undetectable
6giqP-6eomA:
undetectable
6giqT-6eomA:
undetectable		 6giqL-6eomA:
undetectable
6giqP-6eomA:
undetectable
6giqT-6eomA:
undetectable