SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6eon'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CTR_A_TFPA153_1
(CALMODULIN)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 9 ILE A 174
LEU A 166
GLU A 107
ALA A 105
VAL A 112
 None
 1.09A 1ctrA-6eonA:
undetectable		 1ctrA-6eonA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_B_CCSB47_0
(GLUTATHIONE
S-TRANSFERASE)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 7 LEU A 461
THR A 409
GLY A 458
LEU A 455
 None
 0.87A 1gtiB-6eonA:
undetectable		 1gtiB-6eonA:
14.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_B_BEZB1162_0
(PEROXIREDOXIN 5)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 8 PRO A  55
GLY A 578
CYH A 579
PHE A 305
 None
 0.84A 1h4oB-6eonA:
undetectable		 1h4oB-6eonA:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_A_NOVA400_2
(DNA GYRASE SUBUNIT B)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 ASN A  72
PHE A  28
VAL A  44
 None
 0.73A 1kijA-6eonA:
undetectable		 1kijA-6eonA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OC3_A_BEZA201_0
(PEROXIREDOXIN 5)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 8 PRO A  55
GLY A 578
CYH A 579
PHE A 305
 None
 0.81A 1oc3A-6eonA:
undetectable		 1oc3A-6eonA:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM4_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 7 PHE A  79
GLU A 125
ARG A  53
VAL A 120
 None
 1.49A 1om4A-6eonA:
undetectable
1om4B-6eonA:
undetectable		 1om4A-6eonA:
19.01
1om4B-6eonA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHS_A_CLMA999_0
(PROTEIN
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE))		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 VAL A 557
ILE A 368
ILE A 371
PHE A 535
VAL A 555
 None
 0.92A 1qhsA-6eonA:
undetectable		 1qhsA-6eonA:
12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_D_NCAD349_0
(ADP-RIBOSYL CYCLASE)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 GLU A 125
ASN A  81
TRP A 308
 None
 0.87A 1r15D-6eonA:
1.4		 1r15D-6eonA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_E_NCAE359_0
(ADP-RIBOSYL CYCLASE)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 GLU A 125
ASN A  81
TRP A 308
 None
 0.93A 1r15E-6eonA:
undetectable		 1r15E-6eonA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_F_NCAF369_0
(ADP-RIBOSYL CYCLASE)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 GLU A 125
ASN A  81
TRP A 308
 None
 0.91A 1r15F-6eonA:
1.4		 1r15F-6eonA:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 7 PHE A  79
GLU A 125
ARG A  53
VAL A 120
 None
 1.46A 1zzqA-6eonA:
undetectable
1zzqB-6eonA:
undetectable		 1zzqA-6eonA:
19.01
1zzqB-6eonA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A8T_B_ADNB252_1
(U8 SNORNA-BINDING
PROTEIN X29)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 8 HIS A 668
GLY A 763
ILE A 765
ASN A 666
 None
 1.00A 2a8tB-6eonA:
undetectable		 2a8tB-6eonA:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_D_ASDD1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 7 TYR A 119
ILE A 477
GLY A 127
PHE A 313
 None
 1.01A 2vctD-6eonA:
undetectable		 2vctD-6eonA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 6 ILE A 588
MET A 547
THR A 573
LEU A 574
 None
 1.02A 3ag1N-6eonA:
undetectable
3ag1W-6eonA:
undetectable		 3ag1N-6eonA:
19.85
3ag1W-6eonA:
6.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_2
(GLUCOSYLTRANSFERASE-
SI)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 LEU A 141
TRP A 131
TYR A 147
 None
 0.93A 3aicA-6eonA:
2.6		 3aicA-6eonA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_2
(GLUCOSYLTRANSFERASE-
SI)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 LEU A 141
TRP A 131
TYR A 147
 None
 0.93A 3aicB-6eonA:
3.5		 3aicB-6eonA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_2
(GLUCOSYLTRANSFERASE-
SI)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 LEU A 141
TRP A 131
TYR A 147
 None
 0.95A 3aicE-6eonA:
4.2		 3aicE-6eonA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_2
(GLUCOSYLTRANSFERASE-
SI)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 LEU A 141
TRP A 131
TYR A 147
 None
 0.99A 3aicF-6eonA:
2.7		 3aicF-6eonA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_2
(GLUCOSYLTRANSFERASE-
SI)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 LEU A 141
TRP A 131
TYR A 147
 None
 0.93A 3aicG-6eonA:
undetectable		 3aicG-6eonA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_2
(GLUCOSYLTRANSFERASE-
SI)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 LEU A 141
TRP A 131
TYR A 147
 None
 0.98A 3aicH-6eonA:
4.4		 3aicH-6eonA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APW_B_DP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 VAL A 465
ILE A 405
LEU A 134
GLU A 396
ARG A 470
 None
 1.30A 3apwB-6eonA:
undetectable		 3apwB-6eonA:
12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA608_1
(CHITINASE A)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 6 ASN A 708
ALA A 270
HIS A 267
ASP A 266
 None
 1.17A 3aruA-6eonA:
11.8		 3aruA-6eonA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_A_VD3A701_2
(CYTOCHROME P450 2R1)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 MET A 547
VAL A 576
GLU A 602
 None
 0.78A 3c6gA-6eonA:
undetectable		 3c6gA-6eonA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 7 ARG A  53
VAL A 120
PHE A  79
GLU A 125
 None
 1.46A 3hsnA-6eonA:
undetectable
3hsnB-6eonA:
undetectable		 3hsnA-6eonA:
19.01
3hsnB-6eonA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSN_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 7 PHE A  79
GLU A 125
ARG A  53
VAL A 120
 None
 1.46A 3hsnA-6eonA:
undetectable
3hsnB-6eonA:
undetectable		 3hsnA-6eonA:
19.01
3hsnB-6eonA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 7 ARG A  53
VAL A 120
PHE A  79
GLU A 125
 None
 1.47A 3hsoA-6eonA:
undetectable
3hsoB-6eonA:
undetectable		 3hsoA-6eonA:
19.01
3hsoB-6eonA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_C_SAMC301_1
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 SER A 194
ASP A 198
ASP A 225
 None
 0.86A 3iv6C-6eonA:
undetectable		 3iv6C-6eonA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JZ0_B_CLYB900_1
(LINCOSAMIDE
NUCLEOTIDYLTRANSFERA
SE)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 8 GLU A 680
GLU A 678
PHE A 660
ILE A 748
 None
CA  A 802 (-3.4A)
None
None
 1.05A 3jz0B-6eonA:
undetectable		 3jz0B-6eonA:
17.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_C_ADNC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 5 LEU A 604
GLN A 572
THR A 573
GLU A 602
 None
 1.49A 3n58C-6eonA:
undetectable		 3n58C-6eonA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXV_D_MTXD2000_2
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 LEU A 156
ARG A 142
ASN A  81
 None
 0.72A 3qxvD-6eonA:
2.2		 3qxvD-6eonA:
10.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 7 ARG A  53
VAL A 120
PHE A  79
GLU A 125
 None
 1.46A 3ufoA-6eonA:
undetectable
3ufoB-6eonA:
undetectable		 3ufoA-6eonA:
19.01
3ufoB-6eonA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A  53
VAL A 120
PHE A  79
GLU A 125
 None
 1.35A 3ufrA-6eonA:
undetectable
3ufrB-6eonA:
undetectable		 3ufrA-6eonA:
19.01
3ufrB-6eonA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 SER A 404
GLY A 403
GLN A 400
 None
 0.55A 3v4tH-6eonA:
undetectable		 3v4tH-6eonA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_J_ACHJ301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 8 ARG A 275
LEU A 280
TYR A 323
TYR A 297
 None
None
None
GLA  A 801 (-4.5A)
 1.30A 3wipF-6eonA:
undetectable
3wipJ-6eonA:
undetectable		 3wipF-6eonA:
14.25
3wipJ-6eonA:
14.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AE1_B_NCAB1536_0
(DIPHTHERIA TOXIN)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 5 HIS A 300
GLY A 302
TYR A 323
GLU A  48
 None
 1.38A 4ae1B-6eonA:
undetectable		 4ae1B-6eonA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BUP_B_SAMB500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 HIS A 267
GLU A 273
ASN A 713
 None
 1.04A 4bupB-6eonA:
0.5		 4bupB-6eonA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1Y_A_RBFA1176_1
(PUTATIVE PROTEASE I)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 8 GLN A 572
ASN A 546
THR A 601
TRP A 550
 None
 1.41A 4d1yA-6eonA:
undetectable
4d1yB-6eonA:
undetectable		 4d1yA-6eonA:
15.50
4d1yB-6eonA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJE_A_C2FA300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 GLU A 525
ASN A 523
LEU A 406
ASP A 462
GLY A 435
 None
 1.32A 4djeA-6eonA:
7.7		 4djeA-6eonA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5E_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 7 ARG A  53
VAL A 120
PHE A  79
GLU A 125
 None
 1.48A 4k5eA-6eonA:
undetectable
4k5eB-6eonA:
undetectable		 4k5eA-6eonA:
19.01
4k5eB-6eonA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_B_PARB500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 9 PHE A 722
SER A 720
THR A 235
TYR A 325
GLY A 263
 None
None
None
GLA  A 801 (-4.7A)
None
 1.38A 4qb9B-6eonA:
0.0		 4qb9B-6eonA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RYA_A_MTLA501_1
(ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (SORBITOL))		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 GLU A 259
TYR A 323
GLU A 123
 GLA  A 801 (-2.7A)
None
GLA  A 801 (-2.8A)
 0.70A 4ryaA-6eonA:
undetectable		 4ryaA-6eonA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_K_CHDK103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 11 LEU A 452
ASN A 434
LEU A 433
ARG A 460
LEU A 461
 None
 1.14A 4wg0I-6eonA:
undetectable
4wg0J-6eonA:
undetectable
4wg0K-6eonA:
undetectable		 4wg0I-6eonA:
2.40
4wg0J-6eonA:
2.40
4wg0K-6eonA:
2.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_L_CHDL103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 7 ASN A 434
LEU A 433
ARG A 460
LEU A 461
LEU A 452
 None
 1.26A 4wg0L-6eonA:
undetectable
4wg0M-6eonA:
undetectable		 4wg0L-6eonA:
2.40
4wg0M-6eonA:
2.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YDQ_B_HFGB802_0
(PROLINE--TRNA LIGASE)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 GLU A 388
VAL A 503
THR A 409
SER A 412
GLY A 458
 None
 1.18A 4ydqB-6eonA:
undetectable		 4ydqB-6eonA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_ACTA605_0
(SERUM ALBUMIN)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 6 TYR A  77
GLY A 117
GLU A 180
ASN A 181
 GLA  A 801 (-4.5A)
None
None
GLA  A 801 (-2.9A)
 1.21A 4zbqA-6eonA:
undetectable		 4zbqA-6eonA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE2_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 5 ALA A 664
TYR A 768
PRO A 755
PHE A 751
 None
 0.97A 4ze2A-6eonA:
undetectable		 4ze2A-6eonA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_2
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 5 PHE A 512
HIS A 385
LEU A 383
PRO A 507
 None
 1.35A 5csyB-6eonA:
10.3		 5csyB-6eonA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_2
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 GLU A  48
TRP A 261
ASN A 181
 None
GLA  A 801 (-4.1A)
GLA  A 801 (-2.9A)
 1.03A 5dv4A-6eonA:
undetectable		 5dv4A-6eonA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 6 ARG A  53
VAL A 120
PHE A  79
GLU A 125
 None
 1.46A 5fvrA-6eonA:
undetectable
5fvrB-6eonA:
undetectable		 5fvrA-6eonA:
19.01
5fvrB-6eonA:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSM_A_GCSA801_1
(EXO-BETA-D-GLUCOSAMI
NIDASE)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 TYR A  77
CYH A 121
GLU A 123
GLU A 259
TYR A 297
 GLA  A 801 (-4.5A)
GLA  A 801 (-3.3A)
GLA  A 801 (-2.8A)
GLA  A 801 (-2.7A)
GLA  A 801 (-4.5A)
 0.37A 5gsmA-6eonA:
36.2		 5gsmA-6eonA:
24.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSM_B_GCSB801_1
(EXO-BETA-D-GLUCOSAMI
NIDASE)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 TYR A  77
CYH A 121
GLU A 123
GLU A 259
TYR A 297
 GLA  A 801 (-4.5A)
GLA  A 801 (-3.3A)
GLA  A 801 (-2.8A)
GLA  A 801 (-2.7A)
GLA  A 801 (-4.5A)
 0.36A 5gsmB-6eonA:
36.7		 5gsmB-6eonA:
24.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ERYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 6 ASP A 427
HIS A 426
ILE A 422
TYR A 407
 None
 1.26A 5ih0A-6eonA:
undetectable		 5ih0A-6eonA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IMS_B_ACTB713_0
(ACETOLACTATE
SYNTHASE CATALYTIC
SUBUNIT,
MITOCHONDRIAL)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		3 / 3 GLY A 171
GLN A 106
LYS A  26
 None
 0.95A 5imsB-6eonA:
undetectable		 5imsB-6eonA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM2_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 9 LEU A 163
ALA A  99
ASP A  97
VAL A 112
ILE A 174
 None
 1.11A 5om2A-6eonA:
undetectable
5om2B-6eonA:
undetectable		 5om2A-6eonA:
6.60
5om2B-6eonA:
4.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TDZ_A_ADNA905_1
(ATP-CITRATE SYNTHASE)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 6 THR A 657
ASP A 745
LEU A 742
ASP A 741
 None
 1.04A 5tdzA-6eonA:
2.1		 5tdzA-6eonA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U6N_A_SALA505_1
(UDP-GLYCOSYLTRANSFER
ASE 74F2)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 8 SER A 317
HIS A 267
PHE A 265
THR A 721
 None
None
GLA  A 801 (-4.7A)
CA  A 802 (-3.6A)
 1.31A 5u6nA-6eonA:
3.6		 5u6nA-6eonA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U6N_B_SALB504_1
(UDP-GLYCOSYLTRANSFER
ASE 74F2)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 6 SER A 317
HIS A 267
PHE A 265
THR A 721
 None
None
GLA  A 801 (-4.7A)
CA  A 802 (-3.6A)
 1.30A 5u6nB-6eonA:
2.1		 5u6nB-6eonA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB311_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 4 PHE A 544
PRO A 364
TYR A 575
TYR A  58
 None
 1.37A 5uunB-6eonA:
0.0		 5uunB-6eonA:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V4V_A_NCAA402_0
(NADPH DEHYDROGENASE
3)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 8 THR A 721
HIS A 267
ASN A 312
PHE A 473
 CA  A 802 (-3.6A)
None
None
None
 1.20A 5v4vA-6eonA:
9.7		 5v4vA-6eonA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V4V_B_NCAB402_0
(NADPH DEHYDROGENASE
3)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		4 / 8 THR A 721
HIS A 267
ASN A 312
PHE A 473
 CA  A 802 (-3.6A)
None
None
None
 1.18A 5v4vB-6eonA:
9.5		 5v4vB-6eonA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_A_HFGA1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 GLU A 388
VAL A 503
THR A 409
SER A 412
GLY A 458
 None
 1.19A 5xipA-6eonA:
undetectable		 5xipA-6eonA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_A_QPSA601_2
(-)		 6eon BETA-GALACTOSIDASE
(Bacteroides
thetaiotaomicron) 		5 / 12 GLY A 469
HIS A 307
PRO A 607
VAL A 508
GLU A 466
 None
 1.17A 6gngA-6eonA:
undetectable		 6gngA-6eonA:
22.52