SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6eoq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DF7_A_MTXA501_2
(DIHYDROFOLATE
REDUCTASE)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		3 / 3 TRP A 210
ARG A 274
THR A 223
 None
 0.95A 1df7A-6eoqA:
undetectable		 1df7A-6eoqA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JZS_A_MRCA1301_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		5 / 11 GLY A 686
HIS A 424
GLU A 495
GLN A 684
ILE A 504
 None
 1.22A 1jzsA-6eoqA:
undetectable		 1jzsA-6eoqA:
8.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WSV_A_THHA3001_1
(AMINOMETHYLTRANSFERA
SE)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		3 / 3 ASP A 251
GLU A 690
TYR A 644
 None
 0.81A 1wsvA-6eoqA:
undetectable		 1wsvA-6eoqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_A_715A801_1
(DIPEPTIDYL PEPTIDASE
IV)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		8 / 12 GLU A 249
TYR A 644
VAL A 756
TYR A 762
TYR A 766
ASN A 810
VAL A 811
HIS A 840
 None
 0.52A 1x70A-6eoqA:
undetectable		 1x70A-6eoqA:
6.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_B_715B801_1
(DIPEPTIDYL PEPTIDASE
IV)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		8 / 12 GLU A 249
SER A 730
VAL A 756
TYR A 762
TYR A 766
ASN A 810
VAL A 811
HIS A 840
 None
 0.53A 1x70B-6eoqA:
undetectable		 1x70B-6eoqA:
6.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y7I_A_SALA501_1
(SALICYLIC
ACID-BINDING PROTEIN
2)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		5 / 9 GLY A 733
ALA A 752
SER A 736
LEU A 737
LEU A 800
 None
 1.38A 1y7iA-6eoqA:
12.0		 1y7iA-6eoqA:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZEA_A_DHIA6_0
(MONOCLONAL
ANTI-CHOLERA TOXIN
IGG1 KAPPA ANTIBODY,
H CHAIN
MONOCLONAL
ANTI-CHOLERA TOXIN
IGG1 KAPPA ANTIBODY,
L CHAIN
SHORT SYNTHETIC
D-AMINO ACID PEPTIDE
D2)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		3 / 3 TRP A 210
ARG A 188
PHE A 203
 None
 1.09A 1zeaH-6eoqA:
undetectable
1zeaL-6eoqA:
undetectable		 1zeaH-6eoqA:
undetectable
1zeaL-6eoqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_E_RBFE304_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		5 / 12 ILE A 726
LEU A 740
HIS A 742
GLY A 733
LEU A 819
 None
 1.21A 2a58D-6eoqA:
undetectable
2a58E-6eoqA:
2.4		 2a58D-6eoqA:
19.29
2a58E-6eoqA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOU_B_CQAB401_0
(HISTAMINE
N-METHYLTRANSFERASE)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		4 / 7 GLY A 780
PRO A 774
ASP A 772
THR A 767
 None
 1.04A 2aouB-6eoqA:
2.3		 2aouB-6eoqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_A_LEUA1894_0
(AMINOACYL-TRNA
SYNTHETASE)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		4 / 8 TYR A 762
ASP A 763
HIS A 815
HIS A 812
 None
 1.35A 2bteA-6eoqA:
undetectable		 2bteA-6eoqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_D_LEUD1893_0
(AMINOACYL-TRNA
SYNTHETASE)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		4 / 8 TYR A 762
ASP A 763
HIS A 815
HIS A 812
 None
 1.24A 2bteD-6eoqA:
undetectable		 2bteD-6eoqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYT_A_LEUA1301_0
(LEUCYL-TRNA
SYNTHETASE)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		4 / 7 TYR A 762
ASP A 763
HIS A 815
HIS A 812
 None
 1.29A 2bytA-6eoqA:
undetectable		 2bytA-6eoqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYT_D_LEUD1601_0
(LEUCYL-TRNA
SYNTHETASE)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		4 / 7 TYR A 762
ASP A 763
HIS A 815
HIS A 812
 None
 1.27A 2bytD-6eoqA:
undetectable		 2bytD-6eoqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTT_D_H4BD1006_1
(HYPOTHETICAL PROTEIN
PH0634)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		5 / 10 HIS A 526
HIS A 548
THR A 518
THR A 521
GLU A 524
 None
 1.50A 2dttD-6eoqA:
undetectable
2dttF-6eoqA:
undetectable		 2dttD-6eoqA:
20.51
2dttF-6eoqA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTT_E_H4BE1004_1
(HYPOTHETICAL PROTEIN
PH0634)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		5 / 11 HIS A 526
HIS A 548
THR A 518
THR A 521
GLU A 524
 None
 1.45A 2dttD-6eoqA:
undetectable
2dttE-6eoqA:
undetectable		 2dttD-6eoqA:
20.51
2dttE-6eoqA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_B_9CRB501_1
(CYTOCHROME P450 2C8)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		5 / 9 GLY A 646
SER A 682
ILE A 702
VAL A 643
VAL A 675
 None
 1.14A 2nnhB-6eoqA:
undetectable		 2nnhB-6eoqA:
10.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RGU_A_356A901_1
(DIPEPTIDYL PEPTIDASE
4)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		8 / 12 GLU A 249
SER A 730
TYR A 731
VAL A 756
TYR A 762
TYR A 766
VAL A 811
HIS A 840
 None
 0.58A 2rguA-6eoqA:
32.7		 2rguA-6eoqA:
6.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RGU_A_356A901_1
(DIPEPTIDYL PEPTIDASE
4)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		5 / 12 GLU A 249
TYR A 644
TYR A 731
TYR A 762
TYR A 766
 None
 0.62A 2rguA-6eoqA:
32.7		 2rguA-6eoqA:
6.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RGU_B_356B902_1
(DIPEPTIDYL PEPTIDASE
4)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		8 / 11 GLU A 249
SER A 730
TYR A 731
VAL A 756
TYR A 762
TYR A 766
VAL A 811
HIS A 840
 None
 0.50A 2rguB-6eoqA:
32.7		 2rguB-6eoqA:
6.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RGU_B_356B902_1
(DIPEPTIDYL PEPTIDASE
4)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		5 / 11 GLU A 249
TYR A 644
TYR A 731
TYR A 762
TYR A 766
 None
 0.60A 2rguB-6eoqA:
32.7		 2rguB-6eoqA:
6.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEY_A_EV1A1771_1
(CAMP AND
CAMP-INHIBITED CGMP
3', 5'-CYCLIC
PHOSPHODIESTERASE)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		5 / 12 LEU A 338
LEU A 381
VAL A 379
ILE A 352
PHE A 346
 None
 1.26A 2weyA-6eoqA:
undetectable		 2weyA-6eoqA:
14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X7H_A_PFNA1374_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		4 / 6 PRO A 236
SER A 283
GLU A 279
CYH A 225
 None
 1.27A 2x7hA-6eoqA:
2.4		 2x7hA-6eoqA:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJM_A_BJMA1_1
(DIPEPTIDYL PEPTIDASE
4)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		10 / 12 GLU A 249
TYR A 644
SER A 730
TYR A 731
VAL A 756
TYR A 762
TYR A 766
ASN A 810
VAL A 811
HIS A 840
 None
 0.52A 3bjmA-6eoqA:
31.9		 3bjmA-6eoqA:
6.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJM_A_BJMA1_1
(DIPEPTIDYL PEPTIDASE
4)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		5 / 12 GLU A 249
TYR A 644
SER A 730
TYR A 762
VAL A 811
 None
 1.10A 3bjmA-6eoqA:
31.9		 3bjmA-6eoqA:
6.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJM_B_BJMB2_1
(DIPEPTIDYL PEPTIDASE
4)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		5 / 12 GLU A 249
TYR A 644
SER A 730
TYR A 762
VAL A 811
 None
 1.10A 3bjmB-6eoqA:
31.9		 3bjmB-6eoqA:
6.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJM_B_BJMB2_1
(DIPEPTIDYL PEPTIDASE
4)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		9 / 12 GLU A 249
TYR A 644
SER A 730
VAL A 756
TYR A 762
TYR A 766
ASN A 810
VAL A 811
HIS A 840
 None
 0.51A 3bjmB-6eoqA:
31.9		 3bjmB-6eoqA:
6.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_A_T22A800_1
(DIPEPTIDYL PEPTIDASE
4)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		6 / 12 GLU A 249
SER A 730
TYR A 762
ASN A 810
VAL A 811
HIS A 840
 None
 0.84A 3g0bA-6eoqA:
9.4		 3g0bA-6eoqA:
6.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_A_T22A800_1
(DIPEPTIDYL PEPTIDASE
4)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		6 / 12 GLU A 249
TYR A 644
TYR A 731
TYR A 762
TYR A 766
ASN A 810
 None
 0.75A 3g0bA-6eoqA:
9.4		 3g0bA-6eoqA:
6.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_A_T22A800_1
(DIPEPTIDYL PEPTIDASE
4)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		8 / 12 GLU A 249
TYR A 731
VAL A 756
TYR A 762
TYR A 766
ASN A 810
VAL A 811
HIS A 840
 None
 0.51A 3g0bA-6eoqA:
9.4		 3g0bA-6eoqA:
6.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_B_T22B800_1
(DIPEPTIDYL PEPTIDASE
4)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		6 / 12 GLU A 249
SER A 730
TYR A 762
ASN A 810
VAL A 811
HIS A 840
 None
 0.85A 3g0bB-6eoqA:
33.9		 3g0bB-6eoqA:
6.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_B_T22B800_1
(DIPEPTIDYL PEPTIDASE
4)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		6 / 12 GLU A 249
TYR A 644
TYR A 731
TYR A 762
TYR A 766
ASN A 810
 None
 0.76A 3g0bB-6eoqA:
33.9		 3g0bB-6eoqA:
6.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_B_T22B800_1
(DIPEPTIDYL PEPTIDASE
4)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		8 / 12 GLU A 249
TYR A 731
VAL A 756
TYR A 762
TYR A 766
ASN A 810
VAL A 811
HIS A 840
 None
 0.53A 3g0bB-6eoqA:
33.9		 3g0bB-6eoqA:
6.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_C_T22C800_1
(DIPEPTIDYL PEPTIDASE
4)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		6 / 12 GLU A 249
SER A 730
TYR A 762
ASN A 810
VAL A 811
HIS A 840
 None
 0.87A 3g0bC-6eoqA:
34.9		 3g0bC-6eoqA:
6.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_C_T22C800_1
(DIPEPTIDYL PEPTIDASE
4)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		6 / 12 GLU A 249
TYR A 644
TYR A 731
TYR A 762
TYR A 766
ASN A 810
 None
 0.79A 3g0bC-6eoqA:
34.9		 3g0bC-6eoqA:
6.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_C_T22C800_1
(DIPEPTIDYL PEPTIDASE
4)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		8 / 12 GLU A 249
TYR A 731
VAL A 756
TYR A 762
TYR A 766
ASN A 810
VAL A 811
HIS A 840
 None
 0.53A 3g0bC-6eoqA:
34.9		 3g0bC-6eoqA:
6.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_D_T22D800_1
(DIPEPTIDYL PEPTIDASE
4)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		6 / 12 GLU A 249
SER A 730
TYR A 762
ASN A 810
VAL A 811
HIS A 840
 None
 0.85A 3g0bD-6eoqA:
33.8		 3g0bD-6eoqA:
6.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_D_T22D800_1
(DIPEPTIDYL PEPTIDASE
4)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		6 / 12 GLU A 249
TYR A 644
TYR A 731
TYR A 762
TYR A 766
ASN A 810
 None
 0.75A 3g0bD-6eoqA:
33.8		 3g0bD-6eoqA:
6.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G0B_D_T22D800_1
(DIPEPTIDYL PEPTIDASE
4)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		8 / 12 GLU A 249
TYR A 731
VAL A 756
TYR A 762
TYR A 766
ASN A 810
VAL A 811
HIS A 840
 None
 0.51A 3g0bD-6eoqA:
33.8		 3g0bD-6eoqA:
6.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_A_THHA642_1
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		3 / 3 ASN A 810
ASP A 763
ARG A 354
 None
 0.82A 3k13A-6eoqA:
undetectable		 3k13A-6eoqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_C_VIBC223_1
(THIAMINE
PYROPHOSPHOKINASE)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		4 / 8 TYR A 575
LEU A 577
LEU A 541
SER A 561
 None
 1.00A 3lm8A-6eoqA:
undetectable
3lm8C-6eoqA:
undetectable		 3lm8A-6eoqA:
19.57
3lm8C-6eoqA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MEC_A_65BA561_0
(P66 REVERSE
TRANSCRIPTASE)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		5 / 12 LEU A 385
VAL A 403
TYR A 466
LEU A 345
PRO A 341
 None
 1.10A 3mecA-6eoqA:
undetectable		 3mecA-6eoqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QX3_A_EVPA1_1
(DNA TOPOISOMERASE
2-BETA)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		4 / 5 GLY A 501
ASP A 425
ARG A 499
GLN A 247
 None
 1.29A 3qx3A-6eoqA:
undetectable		 3qx3A-6eoqA:
8.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RXF_A_4APA9_1
(CATIONIC TRYPSIN)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		5 / 6 SER A 736
VAL A 643
TRP A 729
GLY A 753
GLY A 733
 None
 1.40A 3rxfA-6eoqA:
undetectable		 3rxfA-6eoqA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ6_A_SAMA300_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		5 / 12 LEU A 855
TYR A 851
ILE A 842
GLY A 753
ILE A 751
 None
 1.01A 3uj6A-6eoqA:
undetectable		 3uj6A-6eoqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UVV_A_T3A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		5 / 12 ILE A 741
ALA A 752
LEU A 819
LEU A 823
ILE A 802
 None
 1.09A 3uvvA-6eoqA:
undetectable		 3uvvA-6eoqA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W2T_A_LF7A801_1
(DIPEPTIDYL PEPTIDASE
4)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		6 / 12 GLU A 249
TYR A 644
SER A 730
TYR A 731
TYR A 762
VAL A 811
 None
 1.18A 3w2tA-6eoqA:
33.0		 3w2tA-6eoqA:
7.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W2T_A_LF7A801_1
(DIPEPTIDYL PEPTIDASE
4)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		10 / 12 GLU A 249
TYR A 644
SER A 730
TYR A 731
VAL A 756
TYR A 762
TYR A 766
ASN A 810
VAL A 811
HIS A 840
 None
 0.54A 3w2tA-6eoqA:
33.0		 3w2tA-6eoqA:
7.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W2T_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		10 / 12 GLU A 249
TYR A 644
SER A 730
TYR A 731
VAL A 756
TYR A 762
TYR A 766
ASN A 810
VAL A 811
HIS A 840
 None
 0.54A 3w2tB-6eoqA:
32.9		 3w2tB-6eoqA:
7.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W2T_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		5 / 12 GLU A 249
TYR A 644
SER A 730
TYR A 762
VAL A 811
 None
 1.15A 3w2tB-6eoqA:
32.9		 3w2tB-6eoqA:
7.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_A_SAMA301_1
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		3 / 3 TYR A 781
THR A 767
GLU A 775
 None
 0.79A 4df3A-6eoqA:
2.1		 4df3A-6eoqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DF3_B_SAMB301_1
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		3 / 3 TYR A 781
THR A 767
GLU A 775
 None
 0.81A 4df3B-6eoqA:
undetectable		 4df3B-6eoqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_A_715A801_1
(DIPEPTIDYL PEPTIDASE
4)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		5 / 12 GLU A 249
TYR A 644
SER A 730
TYR A 762
VAL A 811
 None
 1.11A 4ffwA-6eoqA:
24.6		 4ffwA-6eoqA:
7.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_A_715A801_1
(DIPEPTIDYL PEPTIDASE
4)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		8 / 12 GLU A 249
TYR A 644
SER A 730
VAL A 756
TYR A 762
ASN A 810
VAL A 811
HIS A 840
 None
 0.60A 4ffwA-6eoqA:
24.6		 4ffwA-6eoqA:
7.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_B_715B801_1
(DIPEPTIDYL PEPTIDASE
4)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		8 / 12 GLU A 249
TYR A 644
SER A 730
VAL A 756
TYR A 762
TYR A 766
VAL A 811
HIS A 840
 None
 0.56A 4ffwB-6eoqA:
29.5		 4ffwB-6eoqA:
7.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYK_B_IMNB300_1
(LACTOYLGLUTATHIONE
LYASE)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		5 / 12 ALA A 320
PHE A 386
LEU A 338
GLY A 255
PHE A 368
 None
 1.25A 4kykA-6eoqA:
undetectable
4kykB-6eoqA:
1.2		 4kykA-6eoqA:
19.88
4kykB-6eoqA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCL_B_SAMB301_0
(O-METHYLTRANSFERASE
FAMILY PROTEIN)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		5 / 12 GLN A 373
LEU A 376
LYS A 314
ASN A 312
ALA A 316
 None
 1.31A 4pclB-6eoqA:
2.3		 4pclB-6eoqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RS0_A_IBPA706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		6 / 9 VAL A 513
LEU A 512
LEU A 442
GLY A 536
ALA A 535
LEU A 489
 None
 1.40A 4rs0A-6eoqA:
undetectable		 4rs0A-6eoqA:
6.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDQ_A_BEZA306_0
(GLYCOSIDE HYDROLASE
FAMILY PROTEIN)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		3 / 3 ARG A  35
ASP A  32
TRP A  31
 None
 1.07A 4xdqA-6eoqA:
undetectable		 4xdqA-6eoqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XNX_A_41XA707_1
(TRANSPORTER)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		5 / 11 PHE A 734
VAL A 643
TYR A 644
GLY A 698
GLY A 733
 None
 1.02A 4xnxA-6eoqA:
undetectable		 4xnxA-6eoqA:
8.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP4_A_COCA706_1
(DOPAMINE TRANSPORTER)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		5 / 11 PHE A 734
VAL A 643
TYR A 644
GLY A 698
GLY A 733
 None
 1.15A 4xp4A-6eoqA:
undetectable		 4xp4A-6eoqA:
7.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XPB_A_COCA702_1
(TRANSPORTER)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		5 / 10 PHE A 734
VAL A 643
TYR A 644
GLY A 698
GLY A 733
 None
 1.15A 4xpbA-6eoqA:
undetectable		 4xpbA-6eoqA:
8.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_A_ACTA305_0
(CARBONIC ANHYDRASE 4)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		4 / 4 GLN A 340
VAL A 339
GLU A 337
ILE A 387
 None
 1.19A 5jncA-6eoqA:
undetectable		 5jncA-6eoqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K50_A_ACTA1403_0
(L-THREONINE
3-DEHYDROGENASE)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		4 / 5 SER A 531
VAL A 530
GLY A 536
ALA A 535
 None
 1.02A 5k50A-6eoqA:
undetectable		 5k50A-6eoqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KLA_A_ACTA1505_0
(MATERNAL PROTEIN
PUMILIO)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		3 / 3 HIS A 637
LYS A 635
PHE A  24
 None
 1.43A 5klaA-6eoqA:
undetectable		 5klaA-6eoqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_B_SAMB303_0
(METHYLTRANSFERASE)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		5 / 12 LEU A 385
ALA A 384
GLU A 321
ILE A 275
TRP A 257
 None
 1.05A 5n5dB-6eoqA:
undetectable		 5n5dB-6eoqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_A_ACTA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		3 / 3 GLN A 340
TRP A 468
VAL A 403
 None
 1.12A 6auuA-6eoqA:
0.8		 6auuA-6eoqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B1E_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		10 / 12 GLU A 249
TYR A 644
SER A 730
TYR A 731
VAL A 756
TYR A 762
TYR A 766
ASN A 810
VAL A 811
HIS A 840
 None
 0.55A 6b1eB-6eoqA:
32.0		 6b1eB-6eoqA:
6.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B1E_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		5 / 12 GLU A 249
TYR A 644
SER A 730
TYR A 762
VAL A 811
 None
 1.16A 6b1eB-6eoqA:
32.0		 6b1eB-6eoqA:
6.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BPY_A_ACTA408_0
(THIOREDOXIN
REDUCTASE)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		3 / 3 PRO A 341
SER A 343
SER A 344
 None
 0.63A 6bpyA-6eoqA:
undetectable		 6bpyA-6eoqA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXN_A_SAMA901_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 6eoq DIPEPTIDYL PEPTIDASE
9
(Homo
sapiens) 		5 / 12 LEU A 541
SER A 502
GLN A 516
ARG A 540
ASP A 520
 None
 1.43A 6bxnA-6eoqA:
undetectable		 6bxnA-6eoqA:
undetectable