SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6ep3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_A_TEIA3006_1
(XANTHINE
DEHYDROGENASE)		 6ep3 -
(-) 		5 / 12 LEU A 110
LEU A 190
ARG A 199
VAL A  91
ALA A  98
 None
None
SO4  A 306 (-3.1A)
None
None
 1.12A 1n5xA-6ep3A:
undetectable		 1n5xA-6ep3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N5X_B_TEIB4006_1
(XANTHINE
DEHYDROGENASE)		 6ep3 -
(-) 		5 / 12 LEU A 110
LEU A 190
ARG A 199
VAL A  91
ALA A  98
 None
None
SO4  A 306 (-3.1A)
None
None
 1.12A 1n5xB-6ep3A:
undetectable		 1n5xB-6ep3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_A_VD3A2001_1
(VITAMIN D
HYDROXYLASE)		 6ep3 -
(-) 		5 / 12 ASN A  65
LEU A  54
ILE A  51
ALA A  50
LEU A  36
 None
 1.08A 3a50A-6ep3A:
2.0		 3a50A-6ep3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_C_VD3C2001_1
(VITAMIN D
HYDROXYLASE)		 6ep3 -
(-) 		5 / 11 ILE A  20
ASN A  65
LEU A  54
ILE A  51
LEU A  36
 None
 1.25A 3a50C-6ep3A:
1.6		 3a50C-6ep3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_A_VDYA6178_1
(VITAMIN D
HYDROXYLASE)		 6ep3 -
(-) 		5 / 11 ILE A  20
ASN A  65
LEU A  54
ILE A  51
LEU A  36
 None
 1.20A 3a51A-6ep3A:
undetectable		 3a51A-6ep3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_D_VDYD6178_1
(VITAMIN D
HYDROXYLASE)		 6ep3 -
(-) 		5 / 12 ILE A  20
ASN A  65
LEU A  54
ILE A  51
LEU A  36
 None
 1.18A 3a51D-6ep3A:
undetectable		 3a51D-6ep3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ENH_A_FVXA602_1
(CHOLESTEROL
24-HYDROXYLASE)		 6ep3 -
(-) 		5 / 12 ILE A 202
ALA A 198
ALA A  99
GLY A 102
ALA A  94
 None
None
None
None
EDO  A 303 (-3.8A)
 0.96A 4enhA-6ep3A:
undetectable		 4enhA-6ep3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOI_A_ML1A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 6ep3 -
(-) 		4 / 8 PHE A 206
TYR A  80
PHE A 130
ILE A 152
 None
None
EDO  A 301 (-4.2A)
None
 0.95A 4qoiA-6ep3A:
undetectable
4qoiB-6ep3A:
undetectable		 4qoiA-6ep3A:
undetectable
4qoiB-6ep3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HQA_A_ACRA705_2
(ALPHA-GLUCOSIDASE)		 6ep3 -
(-) 		4 / 8 ASN A 168
GLU A  18
HIS A 162
THR A 124
 None
 1.23A 5hqaA-6ep3A:
undetectable		 5hqaA-6ep3A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA307_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 6ep3 -
(-) 		4 / 4 LEU A  70
LEU A  31
SER A  61
ALA A  68
 None
 1.13A 5uunA-6ep3A:
undetectable		 5uunA-6ep3A:
undetectable