SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6epd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD507_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 6epd 26S PROTEASOME
SUBUNIT S5A
(Rattus
norvegicus) 		4 / 7 ARG W 100
ALA W  96
ILE W 109
ILE W  52
 None
 0.99A 1oniD-6epdW:
undetectable
1oniF-6epdW:
undetectable		 1oniD-6epdW:
undetectable
1oniF-6epdW:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U1J_A_C2FA773_0
(5-METHYLTETRAHYDROPT
EROYLTRIGLUTAMATE--H
OMOCYSTEINE
METHYLTRANSFERASE)		 6epd PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-4
(Rattus
norvegicus;
Rattus
norvegicus) 		4 / 8 ARG 7  85
HIS 1 110
SER 1 146
VAL 1 154
 None
 1.31A 1u1jA-6epd7:
undetectable		 1u1jA-6epd7:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_L_TRPL81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6epd 26S PROTEASOME
SUBUNIT S5A
(Rattus
norvegicus) 		5 / 12 ALA W  93
HIS W 105
ILE W 109
GLY W 102
ALA W  96
 None
 0.99A 1utdL-6epdW:
undetectable
1utdM-6epdW:
undetectable		 1utdL-6epdW:
undetectable
1utdM-6epdW:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_O_TRPO81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6epd 26S PROTEASOME
SUBUNIT S5A
(Rattus
norvegicus) 		5 / 12 ALA W  93
HIS W 105
ILE W 109
GLY W 102
ALA W  96
 None
 1.02A 1utdO-6epdW:
undetectable
1utdP-6epdW:
undetectable		 1utdO-6epdW:
undetectable
1utdP-6epdW:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_P_TRPP81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 6epd 26S PROTEASOME
SUBUNIT S5A
(Rattus
norvegicus) 		5 / 11 ALA W  93
HIS W 105
ILE W 109
GLY W 102
ALA W  96
 None
 1.02A 1utdP-6epdW:
undetectable
1utdQ-6epdW:
undetectable		 1utdP-6epdW:
undetectable
1utdQ-6epdW:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_B_ROFB501_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 6epd PROTEASOME SUBUNIT
BETA TYPE-4
(Rattus
norvegicus) 		3 / 3 MET 7  70
ASN 7  90
GLN 7 113
 None
 1.03A 1xoqB-6epd7:
undetectable		 1xoqB-6epd7:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA702_0
(FERROCHELATASE)		 6epd 26S PROTEASOME
SUBUNIT S5A
(Rattus
norvegicus) 		4 / 7 ARG W 130
LEU W 127
VAL W 138
MET W   7
 None
 1.37A 2hrcA-6epdW:
3.1		 2hrcA-6epdW:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7B_A_BEZA1529_0
(BENZOATE-COENZYME A
LIGASE)		 6epd PROTEASOME SUBUNIT
BETA TYPE-4
(Rattus
norvegicus) 		5 / 9 ALA 7  68
ALA 7  97
GLY 7  96
GLY 7 157
ILE 7 156
 None
 1.28A 2v7bA-6epd7:
undetectable		 2v7bA-6epd7:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7B_A_BEZA1529_0
(BENZOATE-COENZYME A
LIGASE)		 6epd PROTEASOME SUBUNIT
BETA TYPE-4
(Rattus
norvegicus) 		5 / 9 ALA 7  68
ALA 7  97
GLY 7  96
GLY 7 158
ILE 7 156
 None
 1.16A 2v7bA-6epd7:
undetectable		 2v7bA-6epd7:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7B_B_BEZB1529_0
(BENZOATE-COENZYME A
LIGASE)		 6epd PROTEASOME SUBUNIT
BETA TYPE-4
(Rattus
norvegicus) 		5 / 9 ALA 7  68
ALA 7  97
GLY 7  96
GLY 7 157
ILE 7 156
 None
 1.28A 2v7bB-6epd7:
undetectable		 2v7bB-6epd7:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7B_B_BEZB1529_0
(BENZOATE-COENZYME A
LIGASE)		 6epd PROTEASOME SUBUNIT
BETA TYPE-4
(Rattus
norvegicus) 		5 / 9 ALA 7  68
ALA 7  97
GLY 7  96
GLY 7 158
ILE 7 156
 None
 1.16A 2v7bB-6epd7:
undetectable		 2v7bB-6epd7:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_A_HSMA1161_1
(ALLERGEN ARG R 1)		 6epd PROTEASOME SUBUNIT
BETA TYPE-4
(Rattus
norvegicus) 		4 / 5 VAL 7 219
TYR 7 222
VAL 7  55
ASP 7 100
 None
 1.12A 2x45A-6epd7:
undetectable		 2x45A-6epd7:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1161_1
(ALLERGEN ARG R 1)		 6epd PROTEASOME SUBUNIT
BETA TYPE-4
(Rattus
norvegicus) 		4 / 5 VAL 7 219
TYR 7 222
VAL 7  55
ASP 7 100
 None
 1.15A 2x45C-6epd7:
undetectable		 2x45C-6epd7:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZT7_A_GLYA1300_0
(GLYCYL-TRNA
SYNTHETASE)		 6epd PROTEASOME SUBUNIT
BETA TYPE-4
(Rattus
norvegicus) 		4 / 7 GLU 7 196
ARG 7 195
GLU 7 211
TYR 7 188
 None
 1.00A 2zt7A-6epd7:
undetectable		 2zt7A-6epd7:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_A_CLMA221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6epd PROTEASOME SUBUNIT
BETA TYPE-6
(Rattus
norvegicus) 		4 / 4 PHE 1  75
ALA 1 134
CYH 1  77
HIS 1  71
 None
 1.50A 3u9fB-6epd1:
0.0		 3u9fB-6epd1:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_P_CLMP221_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 6epd PROTEASOME SUBUNIT
BETA TYPE-6
(Rattus
norvegicus) 		4 / 4 PHE 1  75
ALA 1 134
CYH 1  77
HIS 1  71
 None
 1.45A 3u9fR-6epd1:
0.0		 3u9fR-6epd1:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB501_1
(HEMOLYTIC LECTIN
CEL-III)		 6epd PROTEASOME SUBUNIT
BETA TYPE-4
(Rattus
norvegicus) 		4 / 5 SER 7  98
GLY 7  99
TRP 7 135
ASP 7 170
 None
 1.35A 3w9tB-6epd7:
undetectable		 3w9tB-6epd7:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1003_1
(HEMOLYTIC LECTIN
CEL-III)		 6epd PROTEASOME SUBUNIT
BETA TYPE-4
(Rattus
norvegicus) 		4 / 5 SER 7  98
GLY 7  99
TRP 7 135
ASP 7 170
 None
 1.35A 3w9tC-6epd7:
undetectable		 3w9tC-6epd7:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD501_1
(HEMOLYTIC LECTIN
CEL-III)		 6epd PROTEASOME SUBUNIT
BETA TYPE-4
(Rattus
norvegicus) 		4 / 5 SER 7  98
GLY 7  99
TRP 7 135
ASP 7 170
 None
 1.36A 3w9tD-6epd7:
undetectable		 3w9tD-6epd7:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1478_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 6epd PROTEASOME SUBUNIT
BETA TYPE-6
(Rattus
norvegicus) 		4 / 6 ASP 1 200
THR 1  35
ILE 1  36
THR 1 231
 None
 1.00A 4acbC-6epd1:
undetectable		 4acbC-6epd1:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 6epd 26S PROTEASOME
SUBUNIT S5A
(Rattus
norvegicus) 		4 / 8 ASN W  12
GLU W 118
ILE W  84
ASP W 119
 None
 0.94A 4d33A-6epdW:
undetectable		 4d33A-6epdW:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 6epd 26S PROTEASOME
SUBUNIT S5A
(Rattus
norvegicus) 		4 / 7 ASN W  12
GLU W 118
ILE W  84
ASP W 119
 None
 1.01A 4d33B-6epdW:
undetectable		 4d33B-6epdW:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 6epd 26S PROTEASOME
SUBUNIT S5A
(Rattus
norvegicus) 		4 / 8 ASN W  12
GLU W 118
ILE W  84
ASP W 119
 None
 0.92A 4d39A-6epdW:
undetectable		 4d39A-6epdW:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 6epd 26S PROTEASOME
SUBUNIT S5A
(Rattus
norvegicus) 		4 / 7 ASN W  12
GLU W 118
ILE W  84
ASP W 119
 None
 0.96A 4d39B-6epdW:
undetectable		 4d39B-6epdW:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_D_ACTD504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 6epd PROTEASOME SUBUNIT
BETA TYPE-6
(Rattus
norvegicus) 		3 / 3 GLY 1 216
SER 1 215
TRP 1 136
 None
 0.99A 4e7cD-6epd1:
undetectable		 4e7cD-6epd1:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOE_F_TR6F101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA2)		 6epd PROTEASOME SUBUNIT
BETA TYPE-4
(Rattus
norvegicus) 		4 / 6 SER 7 142
GLY 7  99
ASP 7 100
GLY 7 157
 None
 0.75A 4koeA-6epd7:
undetectable
4koeB-6epd7:
undetectable
4koeC-6epd7:
undetectable		 4koeA-6epd7:
9.92
4koeB-6epd7:
9.92
4koeC-6epd7:
11.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOE_H_TR6H101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA4)		 6epd PROTEASOME SUBUNIT
BETA TYPE-4
(Rattus
norvegicus) 		4 / 7 SER 7 142
GLY 7  99
ASP 7 100
GLY 7 157
 None
 0.68A 4koeA-6epd7:
undetectable
4koeB-6epd7:
undetectable
4koeD-6epd7:
undetectable		 4koeA-6epd7:
9.92
4koeB-6epd7:
9.92
4koeD-6epd7:
11.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_2
(GLUCOCORTICOID
RECEPTOR)		 6epd PROTEASOME SUBUNIT
BETA TYPE-4
PROTEASOME SUBUNIT
BETA TYPE-6
(Rattus
norvegicus) 		3 / 3 MET 1 153
MET 7  49
TYR 7 106
 None
 1.02A 4p6xI-6epd1:
undetectable		 4p6xI-6epd1:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_A_377A402_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 6epd PROTEASOME SUBUNIT
BETA TYPE-6
(Rattus
norvegicus) 		5 / 9 ALA 1 194
SER 1  51
ALA 1  38
SER 1 163
ALA 1 196
 None
 1.34A 4twdA-6epd1:
undetectable
4twdB-6epd1:
undetectable
4twdC-6epd1:
undetectable
4twdD-6epd1:
undetectable
4twdE-6epd1:
undetectable		 4twdA-6epd1:
13.13
4twdB-6epd1:
13.13
4twdC-6epd1:
13.13
4twdD-6epd1:
13.13
4twdE-6epd1:
13.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_A_377A402_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 6epd PROTEASOME SUBUNIT
BETA TYPE-6
(Rattus
norvegicus) 		5 / 9 ALA 1 196
ALA 1 194
SER 1  51
ALA 1  38
SER 1 163
 None
 1.34A 4twdA-6epd1:
undetectable
4twdB-6epd1:
undetectable
4twdC-6epd1:
undetectable
4twdD-6epd1:
undetectable
4twdE-6epd1:
undetectable		 4twdA-6epd1:
13.13
4twdB-6epd1:
13.13
4twdC-6epd1:
13.13
4twdD-6epd1:
13.13
4twdE-6epd1:
13.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z53_F_TR6F101_1
(DNA TOPOISOMERASE 4
SUBUNIT B,DNA
TOPOISOMERASE 4
SUBUNIT A
E-SITE DNA)		 6epd PROTEASOME SUBUNIT
BETA TYPE-4
(Rattus
norvegicus) 		4 / 6 GLY 7  99
ASP 7 100
GLY 7 157
SER 7 142
 None
 0.73A 4z53A-6epd7:
undetectable
4z53B-6epd7:
undetectable		 4z53A-6epd7:
7.91
4z53B-6epd7:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z53_H_TR6H101_1
(DNA TOPOISOMERASE 4
SUBUNIT B,DNA
TOPOISOMERASE 4
SUBUNIT A
E-SITE DNA)		 6epd PROTEASOME SUBUNIT
BETA TYPE-4
(Rattus
norvegicus) 		4 / 7 GLY 7  99
ASP 7 100
GLY 7 157
SER 7 142
 None
 0.65A 4z53A-6epd7:
undetectable
4z53B-6epd7:
undetectable		 4z53A-6epd7:
7.91
4z53B-6epd7:
7.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ALB_L_TIQL1210_2
(MEDI2452 LIGHT CHAIN)		 6epd PROTEASOME SUBUNIT
BETA TYPE-6
(Rattus
norvegicus) 		4 / 8 SER 1 166
TYR 1 167
GLY 1 164
GLY 1 130
 None
 0.77A 5albL-6epd1:
undetectable		 5albL-6epd1:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ALC_L_TIQL1210_2
(ANTI-TICAGRELOR FAB
72, LIGHT CHAIN)		 6epd PROTEASOME SUBUNIT
BETA TYPE-6
(Rattus
norvegicus) 		4 / 8 SER 1 166
TYR 1 167
GLY 1 164
GLY 1 130
 None
 0.86A 5alcL-6epd1:
undetectable		 5alcL-6epd1:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_D_SAMD301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 6epd PROTEASOME SUBUNIT
BETA TYPE-6
(Rattus
norvegicus) 		5 / 12 ASP 1  50
GLY 1 201
SER 1 202
SER 1  51
GLU 1 198
 None
 1.08A 5hfjD-6epd1:
undetectable		 5hfjD-6epd1:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 6epd 26S PROTEASOME
SUBUNIT S5A
(Rattus
norvegicus) 		5 / 9 GLY W  89
ALA W  96
VAL W  92
GLU W 134
ILE W  52
 None
 1.07A 5i3cA-6epdW:
undetectable		 5i3cA-6epdW:
11.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_B_AC2B301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 6epd 26S PROTEASOME
SUBUNIT S5A
(Rattus
norvegicus) 		5 / 10 GLY W  89
ALA W  96
VAL W  92
GLU W 134
ILE W  52
 None
 1.00A 5i3cB-6epdW:
undetectable		 5i3cB-6epdW:
11.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I6X_A_8PRA705_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 6epd PROTEASOME SUBUNIT
BETA TYPE-4
(Rattus
norvegicus) 		5 / 10 ASP 7 170
ALA 7  67
ILE 7  66
TYR 7 168
GLY 7  99
 None
 1.15A 5i6xA-6epd7:
undetectable		 5i6xA-6epd7:
9.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IL1_A_SAMA601_0
(METTL3)		 6epd 26S PROTEASOME
SUBUNIT S5A
(Rattus
norvegicus) 		5 / 12 ILE W  90
LEU W 124
SER W 115
PHE W  86
GLY W  89
 None
 1.21A 5il1A-6epdW:
undetectable		 5il1A-6epdW:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 6epd PROTEASOME SUBUNIT
BETA TYPE-6
(Rattus
norvegicus) 		5 / 9 ALA 1 192
ALA 1 196
GLY 1  48
ALA 1  38
ASP 1 173
 None
 0.91A 5l5zK-6epd1:
9.7
5l5zL-6epd1:
19.4		 5l5zK-6epd1:
17.06
5l5zL-6epd1:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 6epd PROTEASOME SUBUNIT
BETA TYPE-6
(Rattus
norvegicus) 		5 / 9 ALA 1 194
ALA 1 192
GLY 1  48
ALA 1  38
ASP 1 173
 None
 1.06A 5l5zK-6epd1:
9.7
5l5zL-6epd1:
19.4		 5l5zK-6epd1:
17.06
5l5zL-6epd1:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 6epd PROTEASOME SUBUNIT
BETA TYPE-6
(Rattus
norvegicus) 		5 / 9 ALA 1 192
ALA 1 196
GLY 1  48
ALA 1  38
ASP 1 173
 None
 0.90A 5l5zY-6epd1:
23.3
5l5zZ-6epd1:
19.5		 5l5zY-6epd1:
17.06
5l5zZ-6epd1:
14.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5Z_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-5,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 6epd PROTEASOME SUBUNIT
BETA TYPE-6
(Rattus
norvegicus) 		5 / 9 ALA 1 194
ALA 1 192
GLY 1  48
ALA 1  38
ASP 1 173
 None
 1.06A 5l5zY-6epd1:
23.3
5l5zZ-6epd1:
19.5		 5l5zY-6epd1:
17.06
5l5zZ-6epd1:
14.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF3_B_BO2B305_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 6epd PROTEASOME SUBUNIT
BETA TYPE-6
(Rattus
norvegicus) 		5 / 12 THR 1  35
THR 1  54
THR 1  55
ALA 1  83
SER 1 203
 None
 1.20A 5lf3b-6epd1:
24.6		 5lf3b-6epd1:
97.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5LF3_N_BO2N304_1
(PROTEASOME SUBUNIT
BETA TYPE-6)		 6epd PROTEASOME SUBUNIT
BETA TYPE-6
(Rattus
norvegicus) 		5 / 12 THR 1  35
THR 1  54
THR 1  55
ALA 1  83
SER 1 203
 None
 1.21A 5lf3N-6epd1:
24.7		 5lf3N-6epd1:
97.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MRA_B_DM2B204_1
(SORCIN)		 6epd PROTEASOME SUBUNIT
BETA TYPE-4
(Rattus
norvegicus) 		4 / 6 PHE 7 104
THR 7  53
ASP 7 100
GLY 7  99
 None
 1.24A 5mraA-6epd7:
1.2
5mraB-6epd7:
undetectable		 5mraA-6epd7:
18.56
5mraB-6epd7:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UAN_B_REAB503_1
(RETINOIC ACID
RECEPTOR BETA)		 6epd PROTEASOME SUBUNIT
BETA TYPE-6
(Rattus
norvegicus) 		5 / 12 PHE 1  75
ALA 1 113
ILE 1 133
ILE 1 132
VAL 1 144
 None
 1.34A 5uanB-6epd1:
undetectable		 5uanB-6epd1:
13.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXC_A_ZITA307_1
(PREDICTED
AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 6epd PROTEASOME SUBUNIT
BETA TYPE-4
(Rattus
norvegicus) 		4 / 5 ASP 7  69
GLU 7 244
ARG 7  88
THR 7 237
 None
 1.05A 5uxcA-6epd7:
undetectable		 5uxcA-6epd7:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 6epd PROTEASOME SUBUNIT
BETA TYPE-4
(Rattus
norvegicus) 		4 / 5 TYR 7 168
TYR 7 159
GLY 7 158
GLY 7 157
 None
 1.04A 5x7pA-6epd7:
undetectable		 5x7pA-6epd7:
5.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YSI_A_NCAA1001_0
(UBIQUITINATING/DEUBI
QUITINATING ENZYME
SDEA)		 6epd PROTEASOME SUBUNIT
BETA TYPE-4
(Rattus
norvegicus) 		4 / 6 ARG 7 138
GLY 7 112
SER 7 134
VAL 7 115
 None
 1.06A 5ysiA-6epd7:
undetectable		 5ysiA-6epd7:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWP_A_FVXA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 6epd PROTEASOME SUBUNIT
BETA TYPE-6
(Rattus
norvegicus) 		5 / 9 ILE 1 168
SER 1  81
SER 1 203
SER 1 202
GLY 1 201
 None
 1.29A 6awpA-6epd1:
undetectable		 6awpA-6epd1:
9.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AZ3_1_PAR11803_1
(RRNA ALPHA
RIBOSOMAL PROTEIN
EL18)		 6epd 26S PROTEASOME
SUBUNIT S5A
(Rattus
norvegicus) 		3 / 3 SER W  39
LYS W  40
SER W  43
 None
 0.84A 6az3P-6epdW:
undetectable		 6az3P-6epdW:
20.43