SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6eqt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EJG_D_NCTD501_1 (CYTOCHROME P450 2A13)	6eqt	CENTROMERE PROTEIN N (Homo sapiens)	4 / 6	PHE A 104 ALA A 161 THR A 163 LEU A 175	None	0.96A	4ejgD-6eqtA: undetectable	4ejgD-6eqtA: 10.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4G1B_A_ECNA403_1 (FLAVOHEMOGLOBIN)	6eqt	CENTROMERE PROTEIN N (Homo sapiens)	5 / 12	LEU A 36 THR A 22 VAL A 48 LEU A 52 ILE A 16	None	0.94A	4g1bA-6eqtA: undetectable	4g1bA-6eqtA: 12.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LAK_I_BEZI1_0 (3CL PROTEASE BEZ-TYR-TYR-ASN-ECC PEPTIDE INHIBITOR)	6eqt	CENTROMERE PROTEIN N (Homo sapiens)	3 / 3	SER A 156 TYR A 155 TYR A 154	None	0.65A	5lakA-6eqtA: undetectable 5lakI-6eqtA: undetectable	5lakA-6eqtA: undetectable 5lakI-6eqtA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LAK_J_BEZJ1_0 (3CL PROTEASE BEZ-TYR-TYR-ASN-ECC PEPTIDE INHIBITOR)	6eqt	CENTROMERE PROTEIN N (Homo sapiens)	3 / 3	SER A 156 TYR A 155 TYR A 154	None	0.69A	5lakC-6eqtA: undetectable 5lakJ-6eqtA: undetectable	5lakC-6eqtA: undetectable 5lakJ-6eqtA: undetectable

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4EJG_D_NCTD501_1","CYTOCHROME P450 2A13","6eqt","CENTROMERE PROTEIN N","Homo sapiens",4,"PHE A 104;ALA A 161;THR A 163;LEU A 175","None","0.96A","4ejgD-6eqtA:undetectable","4ejgD-6eqtA:10.50"],["4G1B_A_ECNA403_1","FLAVOHEMOGLOBIN","6eqt","CENTROMERE PROTEIN N","Homo sapiens",5,"LEU A  36;THR A  22;VAL A  48;LEU A  52;ILE A  16","None","0.94A","4g1bA-6eqtA:undetectable","4g1bA-6eqtA:12.56"],["5LAK_I_BEZI1_0","3CL PROTEASE;BEZ-TYR-TYR-ASN-ECC PEPTIDE INHIBITOR","6eqt","CENTROMERE PROTEIN N","Homo sapiens",3,"SER A 156;TYR A 155;TYR A 154","None","0.65A","5lakA-6eqtA:undetectable;5lakI-6eqtA:undetectable","5lakA-6eqtA:undetectable;5lakI-6eqtA:undetectable"],["5LAK_J_BEZJ1_0","3CL PROTEASE;BEZ-TYR-TYR-ASN-ECC PEPTIDE INHIBITOR","6eqt","CENTROMERE PROTEIN N","Homo sapiens",3,"SER A 156;TYR A 155;TYR A 154","None","0.69A","5lakC-6eqtA:undetectable;5lakJ-6eqtA:undetectable","5lakC-6eqtA:undetectable;5lakJ-6eqtA:undetectable"]]