SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6erc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E06_A_IPBA600_0
(ODORANT-BINDING
PROTEIN)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		4 / 6 MET A 214
ASN A 173
ILE A 182
ASN A 178
 None
NA  A 609 (-3.3A)
None
None
 0.97A 1e06A-6ercA:
undetectable		 1e06A-6ercA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM9_A_9CRA201_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		3 / 3 GLN A 481
ILE A 376
HIS A 464
 None
 0.66A 1fm9A-6ercA:
undetectable		 1fm9A-6ercA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I2W_A_CFXA1300_2
(BETA-LACTAMASE)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		4 / 5 PRO A 414
LEU A 418
THR A 317
ARG A 322
 None
None
HEM  A 604 (-3.3A)
HEM  A 604 (-2.4A)
 1.13A 1i2wA-6ercA:
undetectable		 1i2wA-6ercA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I7Q_A_BEZA1501_0
(ANTHRANILATE
SYNTHASE)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		5 / 11 GLU A 236
GLY A 324
HIS A 325
LEU A 240
GLY A  96
 HEM  A 604 (-2.2A)
HEM  A 604 (-3.4A)
HEM  A 604 (-3.5A)
None
HEM  A 604 ( 3.6A)
 1.37A 1i7qA-6ercA:
undetectable		 1i7qA-6ercA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IBG_H_OBNH1_1
(IGG2B-KAPPA 40-50
FAB (HEAVY CHAIN))		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		4 / 6 HIS A 244
LEU A 240
TYR A 290
VAL A 174
 None
 1.23A 1ibgH-6ercA:
undetectable		 1ibgH-6ercA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K74_A_9CRA463_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		3 / 3 GLN A 481
ILE A 376
HIS A 464
 None
 0.63A 1k74A-6ercA:
undetectable		 1k74A-6ercA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_B_VIBB503_1
(YKOF)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		4 / 7 PHE A  46
SER A 313
ILE A 170
THR A 317
 None
None
None
HEM  A 604 (-3.3A)
 0.98A 1sbrB-6ercA:
undetectable		 1sbrB-6ercA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPT_A_SAMA400_1
(VP39)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		3 / 3 ASP A 454
ARG A 408
ASP A 452
 None
 0.91A 1vptA-6ercA:
undetectable		 1vptA-6ercA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_A_ADNA433_2
(ADENOSYLHOMOCYSTEINA
SE)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		3 / 3 THR A 293
GLU A 327
HIS A 464
 None
HEM  A 604 (-3.8A)
None
 0.72A 1xwfA-6ercA:
undetectable		 1xwfA-6ercA:
11.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_B_ADNB433_2
(ADENOSYLHOMOCYSTEINA
SE)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		3 / 3 THR A 293
GLU A 327
HIS A 464
 None
HEM  A 604 (-3.8A)
None
 0.73A 1xwfB-6ercA:
undetectable		 1xwfB-6ercA:
11.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_C_ADNC433_2
(ADENOSYLHOMOCYSTEINA
SE)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		3 / 3 THR A 293
GLU A 327
HIS A 464
 None
HEM  A 604 (-3.8A)
None
 0.72A 1xwfC-6ercA:
undetectable		 1xwfC-6ercA:
11.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_D_ADND433_2
(ADENOSYLHOMOCYSTEINA
SE)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		3 / 3 THR A 293
GLU A 327
HIS A 464
 None
HEM  A 604 (-3.8A)
None
 0.76A 1xwfD-6ercA:
undetectable		 1xwfD-6ercA:
11.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQT_A_AINA596_1
(LACTOPEROXIDASE)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		4 / 6 HIS A 101
ARG A 233
GLU A 236
PHE A 352
 None
HEM  A 604 (-3.1A)
HEM  A 604 (-2.2A)
None
 0.98A 2qqtA-6ercA:
39.5		 2qqtA-6ercA:
9.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAT_A_CLMA301_0
(XENOBIOTIC
ACETYLTRANSFERASE)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		3 / 3 GLY A  29
TYR A 169
SER A  41
 None
 0.77A 2xatA-6ercA:
undetectable		 2xatA-6ercA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_A_ACTA1467_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		4 / 5 ARG A 516
ASP A 250
ILE A 278
GLU A 506
 None
 1.45A 2xrzA-6ercA:
undetectable
2xrzB-6ercA:
undetectable		 2xrzA-6ercA:
undetectable
2xrzB-6ercA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CV9_A_VDXA501_1
(CYTOCHROME P450-SU1)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		5 / 9 SER A  68
ARG A 408
ILE A 412
ILE A 100
GLY A 324
 None
None
None
HEM  A 604 (-3.0A)
HEM  A 604 (-3.4A)
 1.27A 3cv9A-6ercA:
undetectable		 3cv9A-6ercA:
12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGW_A_IMNA597_1
(LACTOPEROXIDASE)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		5 / 9 GLN A  97
HIS A 101
ARG A 233
GLU A 236
PHE A 352
 HEM  A 604 (-3.4A)
None
HEM  A 604 (-3.1A)
HEM  A 604 (-2.2A)
None
 0.72A 3ogwA-6ercA:
39.5		 3ogwA-6ercA:
9.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PY4_A_TYLA598_1
(LACTOPEROXIDASE)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		5 / 5 GLN A  97
HIS A 101
ARG A 233
GLU A 236
PHE A 352
 HEM  A 604 (-3.4A)
None
HEM  A 604 (-3.1A)
HEM  A 604 (-2.2A)
None
 0.83A 3py4A-6ercA:
39.7		 3py4A-6ercA:
9.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QF1_A_PZEA6951_1
(LACTOPEROXIDASE)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		3 / 3 HIS A 101
ARG A 233
GLU A 236
 None
HEM  A 604 (-3.1A)
HEM  A 604 (-2.2A)
 0.80A 3qf1A-6ercA:
39.4		 3qf1A-6ercA:
8.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL6_A_NIMA614_1
(LACTOPEROXIDASE)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		5 / 7 GLN A  97
HIS A 101
ARG A 233
GLU A 236
PHE A 352
 HEM  A 604 (-3.4A)
None
HEM  A 604 (-3.1A)
HEM  A 604 (-2.2A)
None
 0.80A 3ql6A-6ercA:
39.8		 3ql6A-6ercA:
9.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R4X_A_PZAA597_0
(LACTOPEROXIDASE)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		4 / 5 GLN A  97
HIS A 101
ARG A 233
GLU A 236
 HEM  A 604 (-3.4A)
None
HEM  A 604 (-3.1A)
HEM  A 604 (-2.2A)
 0.78A 3r4xA-6ercA:
39.8		 3r4xA-6ercA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R55_A_PZAA597_0
(LACTOPEROXIDASE)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		4 / 5 GLN A  97
HIS A 101
ARG A 233
GLU A 236
 HEM  A 604 (-3.4A)
None
HEM  A 604 (-3.1A)
HEM  A 604 (-2.2A)
 0.73A 3r55A-6ercA:
39.8		 3r55A-6ercA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RLB_B_VIBB187_1
(THIT)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		5 / 12 ILE A 433
GLU A 462
TYR A 415
VAL A 450
ASN A 416
 None
 1.16A 3rlbB-6ercA:
undetectable		 3rlbB-6ercA:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGY_A_ASCA800_0
(LACTOPEROXIDASE)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		4 / 4 HIS A 101
ARG A 233
GLU A 236
PHE A 352
 None
HEM  A 604 (-3.1A)
HEM  A 604 (-2.2A)
None
 0.76A 3tgyA-6ercA:
39.6		 3tgyA-6ercA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYE_B_YTZB902_1
(DIHYDROPTEROATE
SYNTHASE)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		3 / 3 PHE A 331
LYS A 348
SER A 350
 None
 1.25A 3tyeB-6ercA:
undetectable		 3tyeB-6ercA:
13.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BUP_B_SAMB500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		3 / 3 HIS A  87
GLU A  86
ASN A 375
 None
 1.02A 4bupB-6ercA:
undetectable		 4bupB-6ercA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7H_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		3 / 3 ARG A  25
THR A 495
TRP A 492
 None
 1.19A 4d7hA-6ercA:
undetectable		 4d7hA-6ercA:
12.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQ4_A_SALA601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		4 / 7 ARG A  25
THR A 485
ILE A 170
GLY A 167
 None
None
None
NA  A 609 (-3.8A)
 0.94A 4eq4A-6ercA:
undetectable		 4eq4A-6ercA:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQL_A_SALA602_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		4 / 7 ARG A  25
THR A 485
ILE A 170
GLY A 167
 None
None
None
NA  A 609 (-3.8A)
 0.95A 4eqlA-6ercA:
undetectable		 4eqlA-6ercA:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GN6_A_TYLA621_1
(LACTOPEROXIDASE)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		4 / 4 HIS A 101
ARG A 233
GLU A 236
PHE A 352
 None
HEM  A 604 (-3.1A)
HEM  A 604 (-2.2A)
None
 0.93A 4gn6A-6ercA:
39.6		 4gn6A-6ercA:
9.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IG5_A_MMZA616_1
(LACTOPEROXIDASE)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		5 / 5 GLN A  97
HIS A 101
ARG A 233
GLU A 236
LEU A 240
 HEM  A 604 (-3.4A)
None
HEM  A 604 (-3.1A)
HEM  A 604 (-2.2A)
None
 0.72A 4ig5A-6ercA:
39.6		 4ig5A-6ercA:
8.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IG5_B_MMZB617_1
(LACTOPEROXIDASE)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		5 / 5 GLN A  97
HIS A 101
ARG A 233
GLU A 236
LEU A 240
 HEM  A 604 (-3.4A)
None
HEM  A 604 (-3.1A)
HEM  A 604 (-2.2A)
None
 0.69A 4ig5B-6ercA:
39.7		 4ig5B-6ercA:
8.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KSZ_A_CYSA620_0
(LACTOPEROXIDASE)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		3 / 3 ARG A 233
GLU A 236
PHE A 352
 HEM  A 604 (-3.1A)
HEM  A 604 (-2.2A)
None
 0.73A 4kszA-6ercA:
39.8		 4kszA-6ercA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_A_HFGA803_0
(PROLINE--TRNA LIGASE)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		5 / 12 LEU A 186
VAL A 209
PRO A 206
SER A 242
GLY A 360
 None
 1.32A 4q15A-6ercA:
undetectable		 4q15A-6ercA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_B_HFGB803_0
(PROLINE--TRNA LIGASE)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		5 / 12 LEU A 186
VAL A 209
PRO A 206
SER A 242
GLY A 360
 None
 1.32A 4q15B-6ercA:
undetectable		 4q15B-6ercA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_A_3CJA607_1
(LACTOPEROXIDASE)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		3 / 3 GLN A  97
HIS A 101
ARG A 233
 HEM  A 604 (-3.4A)
None
HEM  A 604 (-3.1A)
 0.74A 4qyqA-6ercA:
13.4		 4qyqA-6ercA:
8.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_B_3CJB607_1
(LACTOPEROXIDASE)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		3 / 3 GLN A  97
HIS A 101
ARG A 233
 HEM  A 604 (-3.4A)
None
HEM  A 604 (-3.1A)
 0.71A 4qyqB-6ercA:
29.6		 4qyqB-6ercA:
8.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_C_3CJC607_1
(LACTOPEROXIDASE)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		5 / 6 GLN A  97
HIS A 101
ARG A 233
GLU A 236
ARG A 322
 HEM  A 604 (-3.4A)
None
HEM  A 604 (-3.1A)
HEM  A 604 (-2.2A)
HEM  A 604 (-2.4A)
 0.87A 4qyqC-6ercA:
39.0		 4qyqC-6ercA:
8.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYQ_D_3CJD607_1
(LACTOPEROXIDASE)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		4 / 4 GLN A  97
HIS A 101
ARG A 233
GLU A 236
 HEM  A 604 (-3.4A)
None
HEM  A 604 (-3.1A)
HEM  A 604 (-2.2A)
 0.63A 4qyqD-6ercA:
39.4		 4qyqD-6ercA:
8.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R82_A_ACTA205_0
(OXIDOREDUCTASE)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		4 / 5 GLY A  31
ARG A 490
GLU A  23
PHE A 491
 None
 1.25A 4r82A-6ercA:
undetectable
4r82B-6ercA:
undetectable		 4r82A-6ercA:
undetectable
4r82B-6ercA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		5 / 12 GLY A 167
GLY A  29
ASN A  32
LEU A 105
THR A 139
 NA  A 609 (-3.8A)
None
None
HEM  A 604 ( 4.9A)
None
 1.08A 4uckB-6ercA:
undetectable		 4uckB-6ercA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UG5_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		3 / 3 ARG A  25
THR A 495
TRP A 492
 None
 1.20A 4ug5A-6ercA:
undetectable		 4ug5A-6ercA:
12.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGL_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		3 / 3 ARG A  25
THR A 495
TRP A 492
 None
 1.17A 4uglA-6ercA:
undetectable		 4uglA-6ercA:
12.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ4_B_ACTB403_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		3 / 3 ARG A 249
ASP A 250
ARG A 253
 None
 0.55A 4wq4B-6ercA:
undetectable		 4wq4B-6ercA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YDQ_A_HFGA802_0
(PROLINE--TRNA LIGASE)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		5 / 12 LEU A 186
VAL A 209
PRO A 206
SER A 242
GLY A 360
 None
 1.35A 4ydqA-6ercA:
undetectable		 4ydqA-6ercA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_C_ACTC401_0
(PROTON-GATED ION
CHANNEL)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		4 / 7 ILE A 369
ARG A 366
VAL A 524
ILE A 521
 None
 0.99A 4zzbC-6ercA:
undetectable
4zzbD-6ercA:
undetectable		 4zzbC-6ercA:
undetectable
4zzbD-6ercA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTI_E_LFXE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		4 / 5 SER A 350
ARG A 233
GLY A 234
GLU A 231
 None
HEM  A 604 (-3.1A)
None
None
 1.01A 5btiA-6ercA:
undetectable
5btiB-6ercA:
undetectable		 5btiA-6ercA:
10.86
5btiB-6ercA:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTI_F_LFXF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		4 / 5 SER A 350
ARG A 233
GLY A 234
GLU A 231
 None
HEM  A 604 (-3.1A)
None
None
 1.00A 5btiC-6ercA:
undetectable
5btiD-6ercA:
undetectable		 5btiC-6ercA:
10.86
5btiD-6ercA:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FF1_A_MMZA601_1
(LACTOPEROXIDASE)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		5 / 5 GLN A  97
HIS A 101
ARG A 233
GLU A 236
LEU A 240
 HEM  A 604 (-3.4A)
None
HEM  A 604 (-3.1A)
HEM  A 604 (-2.2A)
None
 0.68A 5ff1A-6ercA:
12.2		 5ff1A-6ercA:
8.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FF1_A_MMZA602_1
(LACTOPEROXIDASE)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		5 / 5 GLN A  97
HIS A 101
ARG A 233
GLU A 236
LEU A 240
 HEM  A 604 (-3.4A)
None
HEM  A 604 (-3.1A)
HEM  A 604 (-2.2A)
None
 0.68A 5ff1A-6ercA:
12.2		 5ff1A-6ercA:
8.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FF1_B_MMZB601_1
(LACTOPEROXIDASE)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		5 / 5 GLN A  97
HIS A 101
ARG A 233
GLU A 236
LEU A 240
 HEM  A 604 (-3.4A)
None
HEM  A 604 (-3.1A)
HEM  A 604 (-2.2A)
None
 0.67A 5ff1B-6ercA:
39.7		 5ff1B-6ercA:
8.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FF1_B_MMZB613_1
(LACTOPEROXIDASE)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		5 / 5 GLN A  97
HIS A 101
ARG A 233
GLU A 236
LEU A 240
 HEM  A 604 (-3.4A)
None
HEM  A 604 (-3.1A)
HEM  A 604 (-2.2A)
None
 0.67A 5ff1B-6ercA:
39.7		 5ff1B-6ercA:
8.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6C_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		3 / 3 ARG A  25
THR A 495
TRP A 492
 None
 1.19A 5g6cA-6ercA:
undetectable		 5g6cA-6ercA:
11.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HPW_A_3CJA609_1
(LACTOPEROXIDASE)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		4 / 5 GLN A  97
HIS A 101
ARG A 233
GLU A 236
 HEM  A 604 (-3.4A)
None
HEM  A 604 (-3.1A)
HEM  A 604 (-2.2A)
 0.81A 5hpwA-6ercA:
13.3		 5hpwA-6ercA:
8.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HPW_A_3CJA609_1
(LACTOPEROXIDASE)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		4 / 5 GLN A  97
HIS A 101
GLU A 236
ARG A 322
 HEM  A 604 (-3.4A)
None
HEM  A 604 (-2.2A)
HEM  A 604 (-2.4A)
 0.38A 5hpwA-6ercA:
13.3		 5hpwA-6ercA:
8.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HPW_B_3CJB609_1
(LACTOPEROXIDASE)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		4 / 4 GLN A  97
HIS A 101
ARG A 233
ARG A 322
 HEM  A 604 (-3.4A)
None
HEM  A 604 (-3.1A)
HEM  A 604 (-2.4A)
 0.71A 5hpwB-6ercA:
29.6		 5hpwB-6ercA:
8.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HPW_C_3CJC609_1
(LACTOPEROXIDASE)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		5 / 6 GLN A  97
HIS A 101
ARG A 233
GLU A 236
ARG A 322
 HEM  A 604 (-3.4A)
None
HEM  A 604 (-3.1A)
HEM  A 604 (-2.2A)
HEM  A 604 (-2.4A)
 0.87A 5hpwC-6ercA:
39.2		 5hpwC-6ercA:
8.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HPW_D_3CJD609_1
(LACTOPEROXIDASE)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		4 / 4 GLN A  97
HIS A 101
ARG A 233
GLU A 236
 HEM  A 604 (-3.4A)
None
HEM  A 604 (-3.1A)
HEM  A 604 (-2.2A)
 0.63A 5hpwD-6ercA:
39.4		 5hpwD-6ercA:
8.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGY_A_ERYA403_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		5 / 12 ILE A 170
GLY A 172
ASN A 173
ALA A 104
ILE A 243
 None
None
NA  A 609 (-3.3A)
HEM  A 604 ( 3.9A)
None
 1.24A 5igyA-6ercA:
undetectable		 5igyA-6ercA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ERYA404_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		5 / 12 ILE A 170
GLY A 172
ASN A 173
ALA A 104
ILE A 243
 None
None
NA  A 609 (-3.3A)
HEM  A 604 ( 3.9A)
None
 1.21A 5ih0A-6ercA:
undetectable		 5ih0A-6ercA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCE_A_RITA602_1
(CYTOCHROME P450 3A4)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		5 / 12 PHE A  92
PHE A 323
ILE A 478
ILE A 170
GLU A 289
 None
HEM  A 604 ( 3.9A)
None
None
None
 1.05A 5vceA-6ercA:
undetectable		 5vceA-6ercA:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WBV_A_SAMA402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		3 / 3 HIS A  87
GLU A  86
ASN A 375
 None
 1.02A 5wbvA-6ercA:
undetectable		 5wbvA-6ercA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WBV_B_SAMB402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
KMT5B)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		3 / 3 HIS A  87
GLU A  86
ASN A 375
 None
 1.02A 5wbvB-6ercA:
1.4		 5wbvB-6ercA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_A_HFGA1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		5 / 12 LEU A 186
VAL A 209
PRO A 206
SER A 242
GLY A 360
 None
 1.34A 5xiqA-6ercA:
undetectable		 5xiqA-6ercA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA411_0
(UNCHARACTERIZED
PROTEIN KDOO)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		3 / 3 LYS A 257
LEU A 254
ARG A 253
 None
 0.84A 5yw0A-6ercA:
undetectable		 5yw0A-6ercA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		4 / 8 ARG A 322
ASN A 403
GLN A 405
ASP A 409
 HEM  A 604 (-2.4A)
HEM  A 604 ( 4.4A)
None
None
 1.19A 6auuB-6ercA:
undetectable		 6auuB-6ercA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYC_A_1YNA502_2
(PROTEIN CYP51)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		4 / 7 VAL A 209
PRO A 238
PHE A 352
LEU A 241
 None
 1.15A 6aycA-6ercA:
undetectable		 6aycA-6ercA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYC_A_1YNA502_2
(PROTEIN CYP51)		 6erc PEROXINECTIN A
(Dictyostelium
discoideum) 		4 / 7 VAL A 212
PRO A 238
PHE A 352
LEU A 241
 None
 1.21A 6aycA-6ercA:
undetectable		 6aycA-6ercA:
25.00