SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6es9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4G_A_ZMRA466_1
(NEURAMINIDASE)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		5 / 12 ARG A  73
GLU A 477
GLU A  70
GLU A 487
ARG A 548
 None
 1.36A 1a4gA-6es9A:
undetectable		 1a4gA-6es9A:
9.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETB_1_T441128_1
(TRANSTHYRETIN)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		4 / 6 MET A 459
LYS A 456
ALA A 454
LEU A 447
 None
 1.16A 1etb1-6es9A:
undetectable		 1etb1-6es9A:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA155_1
(CALMODULIN)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		4 / 7 GLN A 427
GLU A 237
PHE A 534
ALA A 502
 None
 1.37A 1linA-6es9A:
undetectable		 1linA-6es9A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQN_B_NDRB2001_0
(PROGESTERONE
RECEPTOR)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		5 / 12 LEU A 225
LEU A 216
GLN A 417
LEU A 211
LEU A 208
 None
 1.13A 1sqnB-6es9A:
3.1		 1sqnB-6es9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_Y_BO2Y1403_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		5 / 10 THR A  34
ALA A  33
ALA A  36
VAL A  41
ALA A  59
 None
 1.06A 2f16Y-6es9A:
undetectable
2f16Z-6es9A:
undetectable		 2f16Y-6es9A:
17.21
2f16Z-6es9A:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_A_BEZA1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		5 / 10 LEU A 100
GLY A 101
LEU A 137
LEU A  26
ILE A  72
 None
 1.11A 2f8dA-6es9A:
undetectable		 2f8dA-6es9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_B_BEZB1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		5 / 10 LEU A 100
GLY A 101
LEU A 137
LEU A  26
ILE A  72
 None
 1.11A 2f8dB-6es9A:
undetectable		 2f8dB-6es9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FK8_A_SAMA302_1
(METHOXY MYCOLIC ACID
SYNTHASE 4)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		3 / 3 SER A 474
THR A 236
GLN A 417
 None
 0.86A 2fk8A-6es9A:
undetectable		 2fk8A-6es9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_B_SC2B1294_1
(FICOLIN-2)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		5 / 9 VAL A 246
GLY A 242
SER A 240
LEU A 531
ASP A 527
 None
 1.20A 2j2pB-6es9A:
undetectable
2j2pC-6es9A:
undetectable		 2j2pB-6es9A:
17.89
2j2pC-6es9A:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFS_B_J01B600_1
(ORF12)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		5 / 11 ALA A 422
TYR A 472
GLY A 424
SER A 240
ARG A 175
 None
 1.11A 2xfsB-6es9A:
undetectable		 2xfsB-6es9A:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZW9_B_SAMB801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 2)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		5 / 12 THR A 334
GLY A 403
LEU A 331
LEU A 348
GLU A 399
 None
 0.95A 2zw9B-6es9A:
undetectable		 2zw9B-6es9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AVP_A_MV2A313_1
(PANTOTHENATE KINASE)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		4 / 7 HIS A 321
LEU A 208
TYR A 243
ILE A 244
 None
 0.99A 3avpA-6es9A:
undetectable		 3avpA-6es9A:
12.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B7E_A_ZMRA1001_1
(NEURAMINIDASE)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		5 / 12 ARG A  73
GLU A 477
GLU A  70
GLU A 487
ARG A 548
 None
 1.32A 3b7eA-6es9A:
undetectable		 3b7eA-6es9A:
10.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B7E_B_ZMRB1002_1
(NEURAMINIDASE)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		5 / 12 ARG A  73
GLU A 477
GLU A  70
GLU A 487
ARG A 548
 None
 1.32A 3b7eB-6es9A:
undetectable		 3b7eB-6es9A:
10.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D41_A_FCNA4001_1
(FOMA PROTEIN)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		4 / 8 GLY A 398
GLY A 397
GLY A 264
ILE A 260
 None
 0.65A 3d41A-6es9A:
undetectable		 3d41A-6es9A:
13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		4 / 7 GLY A  99
VAL A 462
ILE A  72
GLN A 106
 None
 0.90A 3fi0E-6es9A:
undetectable		 3fi0E-6es9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		3 / 3 ARG A 342
ASP A 335
ASP A 340
 None
 0.91A 3jb2A-6es9A:
2.2		 3jb2A-6es9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_D_BCZD1001_0
(NEURAMINIDASE)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		5 / 12 ARG A  73
GLU A 477
GLU A  70
GLU A 487
ARG A 548
 None
 1.43A 3k39D-6es9A:
undetectable		 3k39D-6es9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_N_BCZN1001_0
(NEURAMINIDASE)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		5 / 12 ARG A  73
GLU A 477
GLU A  70
GLU A 487
ARG A 548
 None
 1.43A 3k39N-6es9A:
undetectable		 3k39N-6es9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_O_BCZO1001_0
(NEURAMINIDASE)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		5 / 12 ARG A  73
GLU A 477
GLU A  70
GLU A 487
ARG A 548
 None
 1.43A 3k39O-6es9A:
undetectable		 3k39O-6es9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_P_BCZP1001_0
(NEURAMINIDASE)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		5 / 12 ARG A  73
GLU A 477
GLU A  70
GLU A 487
ARG A 548
 None
 1.44A 3k39P-6es9A:
undetectable		 3k39P-6es9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGL_A_RZXA257_1
(CARBOXY-TERMINAL
DOMAIN RNA
POLYMERASE II
POLYPEPTIDE A SMALL
PHOSPHATASE 1)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		4 / 7 VAL A  69
ILE A 107
SER A  28
ARG A  32
 None
None
SO4  A 602 (-2.9A)
None
 0.93A 3pglA-6es9A:
undetectable		 3pglA-6es9A:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SAN_A_ZMRA901_1
(NEURAMINIDASE)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		5 / 12 ARG A  73
GLU A 477
GLU A  70
GLU A 487
ARG A 548
 None
 1.31A 3sanA-6es9A:
undetectable		 3sanA-6es9A:
10.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SAN_B_ZMRB901_1
(NEURAMINIDASE)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		5 / 12 ARG A  73
GLU A 477
GLU A  70
GLU A 487
ARG A 548
 None
 1.32A 3sanB-6es9A:
undetectable		 3sanB-6es9A:
10.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TI5_A_ZMRA1002_1
(NEURAMINIDASE)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		5 / 12 ARG A  73
GLU A 477
GLU A  70
GLU A 487
ARG A 548
 None
 1.32A 3ti5A-6es9A:
undetectable		 3ti5A-6es9A:
10.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TI5_B_ZMRB1002_1
(NEURAMINIDASE)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		5 / 12 ARG A  73
GLU A 477
GLU A  70
GLU A 487
ARG A 548
 None
 1.32A 3ti5B-6es9A:
undetectable		 3ti5B-6es9A:
10.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_B_ZMRB1002_1
(NEURAMINIDASE)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		5 / 12 ARG A  73
GLU A 477
GLU A  70
GLU A 487
ARG A 548
 None
 1.31A 3ticB-6es9A:
undetectable		 3ticB-6es9A:
9.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_C_ZMRC1002_1
(NEURAMINIDASE)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		5 / 12 ARG A  73
GLU A 477
GLU A  70
GLU A 487
ARG A 548
 None
 1.31A 3ticC-6es9A:
undetectable		 3ticC-6es9A:
9.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TIC_D_ZMRD1002_1
(NEURAMINIDASE)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		5 / 12 ARG A  73
GLU A 477
GLU A  70
GLU A 487
ARG A 548
 None
 1.31A 3ticD-6es9A:
undetectable		 3ticD-6es9A:
9.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7N_A_ZMRA601_1
(NEURAMINIDASE)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		5 / 12 ARG A  73
GLU A 477
GLU A  70
GLU A 487
ARG A 548
 None
 1.33A 4b7nA-6es9A:
undetectable		 4b7nA-6es9A:
10.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_A_ZMRA601_1
(NEURAMINIDASE)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		5 / 12 ARG A  73
GLU A 477
GLU A  70
GLU A 487
ARG A 548
 None
 1.39A 4b7qA-6es9A:
undetectable		 4b7qA-6es9A:
10.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_B_ZMRB601_1
(NEURAMINIDASE)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		5 / 12 ARG A  73
GLU A 477
GLU A  70
GLU A 487
ARG A 548
 None
 1.35A 4b7qB-6es9A:
undetectable		 4b7qB-6es9A:
10.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_C_ZMRC601_1
(NEURAMINIDASE)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		5 / 12 ARG A  73
GLU A 477
GLU A  70
GLU A 487
ARG A 548
 None
 1.32A 4b7qC-6es9A:
undetectable		 4b7qC-6es9A:
10.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_D_ZMRD601_1
(NEURAMINIDASE)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		5 / 12 ARG A  73
GLU A 477
GLU A  70
GLU A 487
ARG A 548
 None
 1.37A 4b7qD-6es9A:
undetectable		 4b7qD-6es9A:
10.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_C_ZMRC1470_1
(NEURAMINIDASE)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		5 / 12 ARG A  73
GLU A 477
GLU A  70
GLU A 487
ARG A 548
 None
 1.27A 4cpzC-6es9A:
undetectable		 4cpzC-6es9A:
8.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_D_ZMRD1471_1
(NEURAMINIDASE)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		5 / 12 ARG A  73
GLU A 477
GLU A  70
GLU A 487
ARG A 548
 None
 1.30A 4cpzD-6es9A:
undetectable		 4cpzD-6es9A:
8.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1G_A_LNLA701_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		4 / 5 ARG A 523
VAL A 246
LEU A 239
SER A 240
 None
 1.24A 4e1gA-6es9A:
0.0		 4e1gA-6es9A:
11.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_C_NCTC501_1
(CYTOCHROME P450 2A6)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		4 / 5 PHE A 534
ILE A 244
GLY A 247
THR A 236
 None
 0.97A 4ejjC-6es9A:
undetectable		 4ejjC-6es9A:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_B_SASB804_1
(SEPIAPTERIN
REDUCTASE)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		5 / 12 SER A  76
LEU A  75
ALA A 134
GLY A 105
LEU A 104
 None
 1.20A 4j7xB-6es9A:
undetectable		 4j7xB-6es9A:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA505_0
(FERROCHELATASE,
MITOCHONDRIAL)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		4 / 5 LEU A  23
PRO A  24
LEU A  26
ILE A  72
 None
 1.06A 4klrA-6es9A:
undetectable		 4klrA-6es9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWR_A_ZMRA513_1
(NEURAMINIDASE)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		5 / 12 ARG A  73
GLU A 477
GLU A  70
GLU A 487
ARG A 548
 None
 1.33A 4mwrA-6es9A:
undetectable		 4mwrA-6es9A:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWX_A_ZMRA513_1
(NEURAMINIDASE)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		5 / 12 ARG A  73
GLU A 477
GLU A  70
GLU A 487
ARG A 548
 None
 1.29A 4mwxA-6es9A:
undetectable		 4mwxA-6es9A:
9.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PXM_A_ESTA2000_1
(ESTROGEN RECEPTOR)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		5 / 12 LEU A  65
LEU A  62
ALA A  61
LEU A 126
GLY A 109
 None
 1.13A 4pxmA-6es9A:
undetectable		 4pxmA-6es9A:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_ACTA202_0
(RETINOL-BINDING
PROTEIN 2)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		4 / 6 GLU A 254
THR A 217
LEU A 216
GLN A 417
 None
 1.45A 4qztA-6es9A:
undetectable		 4qztA-6es9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHX_A_LZUA3008_1
(ALDEHYDE OXIDASE)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		4 / 8 HIS A 191
GLU A 518
SER A 522
ARG A 523
 None
 1.15A 4uhxA-6es9A:
undetectable		 4uhxA-6es9A:
4.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHX_A_RTZA3009_1
(ALDEHYDE OXIDASE)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		4 / 8 HIS A 191
GLU A 518
SER A 522
ARG A 523
 None
 1.15A 4uhxA-6es9A:
undetectable		 4uhxA-6es9A:
4.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W9N_C_CCSC1548_0
(ENOYL-[ACYL-CARRIER-
PROTEIN] REDUCTASE)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		3 / 3 ALA A 303
TRP A 310
VAL A 311
 None
 0.38A 4w9nC-6es9A:
undetectable		 4w9nC-6es9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDT_A_ACTA407_0
(FAD:PROTEIN FMN
TRANSFERASE)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		3 / 3 ASP A 340
GLY A 297
ASP A 295
 None
 0.68A 4xdtA-6es9A:
undetectable		 4xdtA-6es9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE1_A_X2NA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		5 / 12 GLY A 489
MET A 490
LEU A 407
PHE A 404
GLY A 297
 None
 1.32A 4ze1A-6es9A:
undetectable		 4ze1A-6es9A:
9.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB3_A_UEGA202_1
(YFIR)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		4 / 4 LEU A 249
ILE A 205
PRO A 201
LEU A 199
 None
 1.21A 5eb3A-6es9A:
undetectable		 5eb3A-6es9A:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGP_A_ERYA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		5 / 12 ILE A 111
PRO A 112
GLU A 487
ALA A 419
VAL A 498
 None
 1.17A 5igpA-6es9A:
undetectable		 5igpA-6es9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGY_A_ERYA403_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		4 / 6 TYR A 381
ASP A 197
ARG A 324
TYR A 243
 None
 1.22A 5igyA-6es9A:
undetectable		 5igyA-6es9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		4 / 7 LEU A 282
VAL A 327
GLU A 350
ILE A 218
 None
 1.16A 5jh7C-6es9A:
undetectable		 5jh7C-6es9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		4 / 8 THR A 165
ALA A 230
ASP A 479
SER A 228
 None
 1.07A 5l5fY-6es9A:
0.0
5l5fZ-6es9A:
undetectable		 5l5fY-6es9A:
17.45
5l5fZ-6es9A:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUO_D_PFLD402_1
(PROTON-GATED ION
CHANNEL)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		5 / 9 THR A 251
SER A 248
THR A 236
SER A 240
ILE A 244
 None
 1.34A 5muoA-6es9A:
5.7
5muoB-6es9A:
5.6
5muoC-6es9A:
undetectable
5muoD-6es9A:
undetectable
5muoE-6es9A:
5.6		 5muoA-6es9A:
24.71
5muoB-6es9A:
24.71
5muoC-6es9A:
24.71
5muoD-6es9A:
24.71
5muoE-6es9A:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		3 / 3 ARG A 333
PHE A 385
LEU A 299
 None
 0.87A 5x1bC-6es9A:
0.0		 5x1bC-6es9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_A_SALA201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		4 / 5 VAL A 524
ARG A 523
GLY A 242
TYR A 243
 None
 1.35A 5x80A-6es9A:
0.8
5x80B-6es9A:
0.9		 5x80A-6es9A:
23.90
5x80B-6es9A:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_D_SALD201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		4 / 5 GLY A 242
TYR A 243
VAL A 524
ARG A 523
 None
 1.37A 5x80C-6es9A:
0.9
5x80D-6es9A:
0.9		 5x80C-6es9A:
23.90
5x80D-6es9A:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_B_GMJB301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 6es9 ACYL-COA
DEHYDROGENASE
(Paracoccus
denitrificans) 		4 / 6 TYR A 472
GLN A 427
GLU A 172
ALA A 230
 None
 1.07A 6djzB-6es9A:
undetectable		 6djzB-6es9A:
undetectable