SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6et0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_B_CCSB47_0
(GLUTATHIONE
S-TRANSFERASE)		 6et0 PQSB
(Pseudomonas
aeruginosa) 		4 / 7 LEU B 247
LEU B 151
GLY B   7
LEU B 148
 None
 0.86A 1gtiB-6et0B:
undetectable		 1gtiB-6et0B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W1B_A_DXCA2034_0
(ACRIFLAVIN
RESISTANCE PROTEIN B)		 6et0 PQSB
(Pseudomonas
aeruginosa) 		3 / 3 PHE B 241
SER B 130
LEU B  64
 None
 0.59A 2w1bA-6et0B:
undetectable		 2w1bA-6et0B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBZ_A_VDXA501_1
(CYTOCHROME P450-SU1)		 6et0 PQSB
(Pseudomonas
aeruginosa) 		5 / 11 SER B 262
LEU B 150
VAL B   6
ILE B   3
ALA B 249
 None
 1.13A 2zbzA-6et0B:
undetectable		 2zbzA-6et0B:
15.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_A_CHDA424_0
(FERROCHELATASE,
MITOCHONDRIAL)		 6et0 PQSB
(Pseudomonas
aeruginosa) 		4 / 8 LEU B 176
SER B 130
GLY B 239
PRO B 240
 None
 0.99A 3hcrA-6et0B:
undetectable		 3hcrA-6et0B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HM1_B_J3ZB1_1
(ESTROGEN RECEPTOR)		 6et0 PQSB
(Pseudomonas
aeruginosa) 		5 / 11 LEU B 107
GLU B 225
LEU B 148
GLY B  61
LEU B  98
 None
 1.38A 3hm1B-6et0B:
undetectable		 3hm1B-6et0B:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HM1_B_J3ZB1_1
(ESTROGEN RECEPTOR)		 6et0 PQSB
(Pseudomonas
aeruginosa) 		5 / 11 LEU B 143
LEU B 133
LEU B 176
GLY B  22
LEU B  17
 None
None
None
None
CSO  B  16 ( 3.8A)
 1.34A 3hm1B-6et0B:
undetectable		 3hm1B-6et0B:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_A_AICA375_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 6et0 PQSB
(Pseudomonas
aeruginosa) 		5 / 11 GLY B   7
LEU B 151
ASN B 121
ARG B 153
LEU B  46
 None
 1.31A 3ndvA-6et0B:
undetectable
3ndvB-6et0B:
undetectable		 3ndvA-6et0B:
13.67
3ndvB-6et0B:
13.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ONN_A_ACTA270_0
(PROTEIN SSM1)		 6et0 PQSB
(Pseudomonas
aeruginosa) 		4 / 5 LEU B 238
ARG B 126
LEU B  10
PRO B  26
 None
 1.31A 3onnA-6et0B:
undetectable		 3onnA-6et0B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_B_IMNB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 6et0 PQSB
(Pseudomonas
aeruginosa) 		5 / 11 GLY B  61
ALA B  93
ILE B  56
LEU B  88
ILE B  80
 None
 1.13A 4xumB-6et0B:
undetectable		 4xumB-6et0B:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TOA_A_ESTA601_1
(ESTROGEN RECEPTOR
BETA)		 6et0 PQSB
(Pseudomonas
aeruginosa) 		5 / 12 ALA B 278
LEU B   2
MET B   1
LEU B 275
LEU B 107
 None
 0.97A 5toaA-6et0B:
undetectable		 5toaA-6et0B:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 6et0 PQSB
(Pseudomonas
aeruginosa) 		5 / 12 LEU B  88
VAL B  42
ALA B   5
ALA B  45
GLY B   7
 None
 1.14A 5tzoB-6et0B:
undetectable		 5tzoB-6et0B:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WYQ_B_SAMB301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 6et0 PQSB
(Pseudomonas
aeruginosa) 		5 / 12 LEU B  21
GLY B 229
LEU B  17
GLY B  23
GLY B  22
 None
None
CSO  B  16 ( 3.8A)
CSO  B  16 ( 4.0A)
None
 1.00A 5wyqB-6et0B:
undetectable		 5wyqB-6et0B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8F_A_ACTA803_0
(UNCHARACTERIZED
PROTEIN)		 6et0 PQSB
(Pseudomonas
aeruginosa) 		3 / 3 GLU B 242
LEU B 243
ARG B 126
 None
 0.82A 6d8fA-6et0B:
undetectable		 6d8fA-6et0B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_B_AQ4B602_0
(CYTOCHROME P450 1A1)		 6et0 PQSB
(Pseudomonas
aeruginosa) 		5 / 12 ILE B 178
PHE B 266
LEU B 196
PHE B 263
ASP B 264
 None
 1.45A 6dwnB-6et0B:
undetectable		 6dwnB-6et0B:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_A_ACTA403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 6et0 PQSB
(Pseudomonas
aeruginosa) 		3 / 3 TYR B 119
ASP B 116
GLN B 117
 None
 0.88A 6g1pA-6et0B:
undetectable		 6g1pA-6et0B:
undetectable