SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '6etx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_H_ACTH3006_0
(BETA-CARBONIC
ANHYDRASE)		 6etx INO80 COMPLEX
SUBUNIT B
(synthetic
construct) 		4 / 6 GLN R 333
CYH R 314
VAL R 311
CYH R 330
 None
ZN  R 401 (-2.5A)
None
ZN  R 401 (-2.4A)
 1.48A 1ekjG-6etxR:
undetectable
1ekjH-6etxR:
undetectable		 1ekjG-6etxR:
undetectable
1ekjH-6etxR:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF502_2
(PHOSPHOLIPASE A2)		 6etx DNA HELICASE INO80
(Homo
sapiens) 		4 / 5 ILE G1088
SER G 829
PRO G 830
PHE G 831
 None
 0.83A 3bjwC-6etxG:
undetectable		 3bjwC-6etxG:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_H_DHIH3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		 6etx DNA HELICASE INO80
(Homo
sapiens) 		3 / 3 LEU G 916
TRP G 913
GLY G1053
 None
 0.76A 3l35A-6etxG:
undetectable
3l35H-6etxG:
undetectable		 3l35A-6etxG:
undetectable
3l35H-6etxG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L35_K_DHIK3_0
(GP41 N-PEPTIDE
HIV ENTRY INHIBITOR
PIE12)		 6etx DNA HELICASE INO80
(Homo
sapiens) 		3 / 3 LEU G 916
TRP G 913
GLY G1053
 None
 0.76A 3l35B-6etxG:
undetectable
3l35K-6etxG:
undetectable		 3l35B-6etxG:
undetectable
3l35K-6etxG:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_ACTA402_0
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 6etx DNA HELICASE INO80
(Homo
sapiens) 		3 / 3 LYS G 842
TYR G 845
ARG G 846
 None
 1.10A 4gc9A-6etxG:
undetectable		 4gc9A-6etxG:
undetectable